For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MVVTLHPKSGLKARLSFLLVMLFVKPLLILFPIFDAGLRQLKWLDRGAQRGPDAPGIQRSRVSLANRPTD LMIPAGTTVAEADTAILYLHGGAFIACGPATHRKITGLLARQLRVPVYVLDYRQLPEVGVGSSVADAVQA YRELLQDYARVIVVGDSAGGFLSGKVIEYAHTHGLPKPVAYVGYSPLLDLDLAANPASTSRHDAYLPKGK LRKLAPKFDRGPVEFAGERRVVAVPVEAYPPTLLITAQDEFLEPDAIALAEKLSAAGVVAKVHSYSWQLH AFPAIAVSRDTAEAVVLSADFINEALSAAEQGPATEQAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0484 | - | - | 100% (319) | putative hydrolase/esterase/lipase |
| M. abscessus ATCC 19977 | MAB_4044c | - | 2e-25 | 31.67% (300) | putative hydrolase/esterase/lipase |
| M. abscessus ATCC 19977 | MAB_0846 | - | 2e-24 | 29.97% (327) | putative lipase/esterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1105 | lipU | 5e-24 | 33.33% (258) | putative lipase LIPU |
| M. gilvum PYR-GCK | Mflv_2042 | - | 1e-26 | 29.65% (317) | alpha/beta hydrolase domain-containing protein |
| M. tuberculosis H37Rv | Rv1076 | lipU | 5e-24 | 33.33% (258) | lipase LipU |
| M. leprae Br4923 | MLBr_00314 | - | 5e-27 | 31.19% (295) | putative esterase |
| M. marinum M | MMAR_4391 | lipU | 1e-24 | 29.07% (313) | lipase LipU |
| M. avium 104 | MAV_3011 | - | 2e-22 | 30.64% (235) | alpha/beta hydrolase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_5271 | - | 8e-26 | 32.53% (289) | esterase |
| M. thermoresistible (build 8) | TH_1370 | lipF | 6e-25 | 30.41% (296) | PROBABLE ESTERASE/LIPASE LIPF |
| M. ulcerans Agy99 | MUL_2832 | lipU_1 | 2e-24 | 31.65% (297) | lipase LipU_1 |
| M. vanbaalenii PYR-1 | Mvan_4675 | - | 7e-28 | 31.17% (324) | alpha/beta hydrolase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1105|M.bovis_AF2122/97 --------------------------------------------------
Rv1076|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4391|M.marinum_M ---MTAPSRVPSNPIHAIRPRDVLKARRLEARRFAISDGAPVEVVESGPS
MLBr_00314|M.leprae_Br4923 ---------------------------------MAISAGAPVEIVESGPS
MUL_2832|M.ulcerans_Agy99 MSGVTTFDKLFGPPYDAIRPRRNRRVG----RRAASGHGAHVEVVESGPS
Mflv_2042|M.gilvum_PYR-GCK ---MTAPSKVPATPHVAINAARGRKQ-----RRFPVSDGAPVEVVEDGPS
Mvan_4675|M.vanbaalenii_PYR-1 ---MTAPSKVPATPHAAIAAARAGKI-----RRFPVSDGAPVEVVEDGPS
TH_1370|M.thermoresistible__bu ---MTAPSKVPRTSPLATRAARGHYS-----RTFPVSDGTPSEYVEDGPS
MSMEG_5271|M.smegmatis_MC2_155 MVAMTAPSKVTRSPRAGIGPGGAYRT-----RKFPVSDSAPVEIVEDGTS
MAV_3011|M.avium_104 --------------------------------------MATTRRVHHRHS
MAB_0484|M.abscessus_ATCC_1997 ----------------------------------------MVVTLHPKSG
Mb1105|M.bovis_AF2122/97 -----------MAVRPVLAVGSYLPHAPWPWGVID-QAARVLLPASTTVR
Rv1076|M.tuberculosis_H37Rv -----------MAVRPVLAVGSYLPHAPWPWGVID-QAARVLLPASTTVR
MMAR_4391|M.marinum_M VAARVATLASRLTIRPVLAVGSHVPHLPWPWGLID-HAAKALVPASATVR
MLBr_00314|M.leprae_Br4923 IAARLASLTSRLTIRPILAVGSYVPQLPWPFGLID-HAARVLLPVTNAAR
MUL_2832|M.ulcerans_Agy99 IAARVVSLASRLTVRPVIAVASHFPHLPWPWSLVD-FALLPITWASGIIG
Mflv_2042|M.gilvum_PYR-GCK VAGRVLGLAAMATIKPFLTVGSYAPKLPWPWGLVD-FAARVLKPAPGTVR
Mvan_4675|M.vanbaalenii_PYR-1 IAGRLMGLAAVATVKPFLTVGSYAPKLPWPWGLLD-FAARVLKPAPGTVR
TH_1370|M.thermoresistible__bu LAGRLTALAAYLTVRPTLAIGSFAPRLPWPWGLLD-FAARAVRPVPGTVR
MSMEG_5271|M.smegmatis_MC2_155 VAGRLASLAAMLTIRPTLAIGSRVPHLPWPFGALN-FAARMLRPSPGTIK
MAV_3011|M.avium_104 PQSVAVSLASRLIVKNAVRAWALTPNLHWPLEYVDSFAGLVPRLGSAGTT
MAB_0484|M.abscessus_ATCC_1997 LKARLSFLLVMLFVKPLLILFPIFDAGLRQLKWLD-RGAQRGPDAPGIQR
:: : . :: . .
Mb1105|M.bovis_AF2122/97 AAVSLPNASAQLVRASGVLPADGTRRAVLYLHGGAFLTCGANSHGRLVEL
Rv1076|M.tuberculosis_H37Rv AAVSLPNASAQLVRASGVLPADGTRRAVLYLHGGAFLTCGANSHGRLVEL
MMAR_4391|M.marinum_M AAVSLPNAAAQLVRAPGVLPADGTRRVVLYLHGGAFLTCGANSHGRLVEL
MLBr_00314|M.leprae_Br4923 AEVNLSNTSAQLVRAAGVRPADGSGRIVLYLHGGAFLGCGANSHRRLVET
MUL_2832|M.ulcerans_Agy99 ERVSLPNASGHLVRASGVPPPDGSRRVVLYMHGGAFLKGGIHSHARLAGT
Mflv_2042|M.gilvum_PYR-GCK ATIKLPHCTAQLVRAAGVLPADGNRTVILYLHGGAFLTCGVNTHGRLVTA
Mvan_4675|M.vanbaalenii_PYR-1 ATIGLPHCNAQLVRAAGVLPADGHRSVILYLHGGAFLTCGVNTHGRLVTA
TH_1370|M.thermoresistible__bu ATIRLPHCTAQLVRAPGVLPADGRRSVVLYLHGGAFLTCGAHTHGRLVTA
MSMEG_5271|M.smegmatis_MC2_155 ATIALPNCTAQLIRADGVLPADGTRSVILYLHGGAFLACGSNTHGGMATS
MAV_3011|M.avium_104 HPVRLEHCAAEWVRAPGVS---GER-AILYLHGGAFLTCGLNTHRPMVTR
MAB_0484|M.abscessus_ATCC_1997 SRVSLANRPTDLMIPAGTTVAEADT-AILYLHGGAFIACGPATHRKITGL
: * : . : . *. . :**:*****: * :* :.
Mb1105|M.bovis_AF2122/97 LSKFADSPVLVVDYRLIPKHSIGMALDDCHDGYRWLRLLGYEPEQIVLAG
Rv1076|M.tuberculosis_H37Rv LSKFADSPVLVVDYRLIPKHSIGMALDDCHDGYRWLRLLGYEPEQIVLAG
MMAR_4391|M.marinum_M LSKFADAPVLIVNYRLMPKHSIGMALDDCHDGYRWLRLLGYDPEQIVLAG
MLBr_00314|M.leprae_Br4923 LSKLADSPILVVNYRLLPKHSIGMALDDCHDGYQWLRRLGYDPEQIVLAG
MUL_2832|M.ulcerans_Agy99 LSKFADSPLLVVNYRLVPKHTVGMALEDCHDAYLWLRLRGHAPEQIVLAG
Mflv_2042|M.gilvum_PYR-GCK LSKCADAPALVVNYRMIPKHSVGTALDDCYDAYKWLRETGYEPEQIVLAG
Mvan_4675|M.vanbaalenii_PYR-1 LSKCADAPVLVVNYRMIPKHSVGTALDDCFDGYKWLRELGYEPDQIVLAG
TH_1370|M.thermoresistible__bu LSEFADSPVLVVNYRMIPKHSVGTAIDDCYDGYQWLRAKGYEPDQIVLAG
MSMEG_5271|M.smegmatis_MC2_155 LSEYADSPVLVVDYRMVPKHSVGTAVDDCYDAYVWLRRAGYEPEQIVVAG
MAV_3011|M.avium_104 LSKAADAAVLAVAYRKLPAHQITDAIDDGLDGLRWLQDRGFDGDRVVVAG
MAB_0484|M.abscessus_ATCC_1997 LARQLRVPVYVLDYRQLPEVGVGSSVADAVQAYRELLQ---DYARVIVVG
*:. . : ** :* : :: * :. * ::::.*
Mb1105|M.bovis_AF2122/97 DSAGGYLALALAQRLQEV------GEEPAALVAISPLLQLAKEHKQAHPN
Rv1076|M.tuberculosis_H37Rv DSAGGYLALALAQRLQEV------GEEPAALVAISPLLQLAKEHKQAHPN
MMAR_4391|M.marinum_M DSAGGYLALTLAQRLQEE------GEEPAALVAISPLLQLAKEQKKAHPN
MLBr_00314|M.leprae_Br4923 DSAGGYLALALAQRLQDV------GEEPAALVAISPLLQLAKKGKQAHPN
MUL_2832|M.ulcerans_Agy99 DSAGGYLAFALAQRLRAR------GEEPAALVAISPLLQLAMRSKKAHPN
Mflv_2042|M.gilvum_PYR-GCK DSAGGYLALALAEKLQAEGINGYVGETPAAVVTMSPLFEIDNEARADHPN
Mvan_4675|M.vanbaalenii_PYR-1 DSAGGYLALSLAERLQAEGINGFVGETPAAIVTMSPLFEIDNEARADHPN
TH_1370|M.thermoresistible__bu DSAGGYLALSLAQRLLDE------GEEPAALVALSPLFEIDNESRAQHPN
MSMEG_5271|M.smegmatis_MC2_155 DSAGGYLGLALAERLLDD------GEVPAALVAMSPLYEIDNRARAEHPN
MAV_3011|M.avium_104 DSAGGYLAFMTTLLAIQN-----EVMEPAGIATVSPFTDTDPARKLKHRN
MAB_0484|M.abscessus_ATCC_1997 DSAGGFLSGKVIEYAHTHG-----LPKPVAYVGYSPLLDLDLAAN-PAST
*****:*. *.. . **: : . .
Mb1105|M.bovis_AF2122/97 IKTDAMFPARAFDALDALVASAAARNQVDGEPEELYEPLEHITPGLPRTL
Rv1076|M.tuberculosis_H37Rv IKTDAMFPARAFDALDALVASAAARNQVDGEPEELYEPLEHITPGLPRTL
MMAR_4391|M.marinum_M IKRDAMFPPKAFDALGELVASAAAKNKIDGKPEELYEPLEHIRPGLPRTL
MLBr_00314|M.leprae_Br4923 AKTDAMFPPKAFDALGRLVASSAAKNKVDDKPEELYEPLDHIAPGLPRTL
MUL_2832|M.ulcerans_Agy99 IKSDAMFPARAFDALVAIVAGAAARNETAGRREEIYEPLEHIAPGLPPTL
Mflv_2042|M.gilvum_PYR-GCK VRTDSMFPPKAFHALVELIEEAAARRMVNGAPEEVYEPLDHIEPGLPRTL
Mvan_4675|M.vanbaalenii_PYR-1 VRTDAMFPPKAFHALVELIEAAAERRMVDGKPEEVYEPLDHIEPGLPRTL
TH_1370|M.thermoresistible__bu IRTDAMFPPRAFSALIELVEEAAERRTTNGRPEEVYEPLDNIEPGLPRTL
MSMEG_5271|M.smegmatis_MC2_155 ARRDAMFPPKAFDALVEIVEAAAAR---NG--EQVYEPLDHIEPGLPRTL
MAV_3011|M.avium_104 ARKCSMFTCRAFSRFAEYLSNAQVLEGHGDS--TVASPVDADLSSLPPVT
MAB_0484|M.abscessus_ATCC_1997 SRHDAYLPKGKLRKLAPKFD--RGPVEFAGERRVVAVPVEAYPP----TL
: : :. : : . . : *:: . .
Mb1105|M.bovis_AF2122/97 IHVSGSEVLLHDAQLAAAKLAAAGVPAEVRVWPGQVHDFQVAASMLPEAI
Rv1076|M.tuberculosis_H37Rv IHVSGSEVLLHDAQLAAAKLAAAGVPAEVRVWPGQVHDFQVAASMLPEAI
MMAR_4391|M.marinum_M IHVSGSEVLLHDAQLAARKLAAVGVPAEVRVWPGQVHDFQVAGPLLPEAT
MLBr_00314|M.leprae_Br4923 IHVSGSEVLLHDAQLAATKLAAVGVPAEIRVWPGQVHVFQAAAPMVPEAT
MUL_2832|M.ulcerans_Agy99 IHVSGAEALLHDARLAAGKLAAAGVRAEVRVWPGQLHDFQVAAPMLPEAT
Mflv_2042|M.gilvum_PYR-GCK IHVSGSEVLLSDARKAARLLAASGVPVEVRIWPGQMHVFQLGAPMVPEAS
Mvan_4675|M.vanbaalenii_PYR-1 IHVSGSEVLLSDARKAARLLAAAGVPVEVRVWPGQMHVFQLGAPAVSEAN
TH_1370|M.thermoresistible__bu IHVSGSEALISDARKAARRLAAAGVPVEIRVWPGQMHVFQIAAPFVPEAK
MSMEG_5271|M.smegmatis_MC2_155 IHVSGSEVLISDARKAARMLCAAGVPVEVHVWPGQMHVFQIAGNLVPEAK
MAV_3011|M.avium_104 IHASSDELLVADAELMAKRLEASGIHCDLHLWDGQIHDFPLAADVLPEGR
MAB_0484|M.abscessus_ATCC_1997 LITAQDEFLEPDAIALAEKLSAAGVVAKVHSYSWQLHAFPAIAVSR-DTA
: .: * * ** * * * *: .:: : *:* * . :
Mb1105|M.bovis_AF2122/97 RSLRQIGEYIREATG-----------------
Rv1076|M.tuberculosis_H37Rv RSLRQIGEYIREATG-----------------
MMAR_4391|M.marinum_M RSLRQIGDYIREATG-----------------
MLBr_00314|M.leprae_Br4923 LSLRQISQYIREATASKASRDRQSL-------
MUL_2832|M.ulcerans_Agy99 YSLRQIGEYIRQATG-----------------
Mflv_2042|M.gilvum_PYR-GCK RSIKQIGEYIREATW-----------------
Mvan_4675|M.vanbaalenii_PYR-1 RSIKQIGEYIREATW-----------------
TH_1370|M.thermoresistible__bu RSLRQIGEYIREATW-----------------
MSMEG_5271|M.smegmatis_MC2_155 RSLRQIGAYIREATW-----------------
MAV_3011|M.avium_104 RAIKYLGDFVKDVTAAGTRFSNVRRLRTAAAG
MAB_0484|M.abscessus_ATCC_1997 EAVVLSADFINEALSAAEQGPATEQAG-----
:: . ::.:.