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RTDTDTWDIQTSVGSTALAVAAGRALARHPANGAPIDPYAELFCRAAGGQWSDLVQGKQSDHALSSEDFG RSFANFQAARTAFFDNFFTTTSDTGVRQVVLLASGLDCRAYRLQWPAETEVYELDQPLVQQFKQETLDAH GAAPSAVRHPISVDLRQDWSTILQESGFDPSRPSAWLVEGLLFFLKSSAQDLLLETIDSLAAPGSHIAVE QRDTYPDIEFEMRRAAAADSAEPGGSPLADFLALIYNESRSEAATWLRGRGWAAERIALLDYMNTSGFEL PAYSSVGWDTLRYTNMVTAAKR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0213c | - | - | 100% (303) | hypothetical protein MAB_0213c |
| M. abscessus ATCC 19977 | MAB_4328c | - | 6e-95 | 57.62% (302) | hypothetical protein MAB_4328c |
| M. abscessus ATCC 19977 | MAB_4606c | - | 1e-57 | 45.32% (278) | hypothetical protein MAB_4606c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0289 | - | 5e-76 | 48.04% (306) | hypothetical protein Mb0289 |
| M. gilvum PYR-GCK | Mflv_0743 | - | 3e-62 | 46.45% (282) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv0281 | - | 6e-76 | 48.04% (306) | hypothetical protein Rv0281 |
| M. leprae Br4923 | MLBr_02640 | - | 7e-54 | 42.36% (288) | hypothetical protein MLBr_02640 |
| M. marinum M | MMAR_0539 | - | 3e-75 | 49.14% (291) | O-methyltransferase |
| M. avium 104 | MAV_4873 | - | 2e-77 | 48.01% (302) | methyltransferase, putative, family protein |
| M. smegmatis MC2 155 | MSMEG_0614 | - | 1e-73 | 49.30% (286) | methyltransferase |
| M. thermoresistible (build 8) | TH_4502 | - | 8e-59 | 43.51% (285) | PUTATIVE methyltransferase |
| M. ulcerans Agy99 | MUL_4402 | - | 5e-55 | 44.41% (295) | O-methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_0104 | - | 9e-59 | 44.48% (281) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0289|M.bovis_AF2122/97 ---MRTEGDSWDITTSVGSTALFVATARALEAQKSDPLVVDPYAEAFCRA
Rv0281|M.tuberculosis_H37Rv ---MRTEGDSWDITTSVGSTALFVATARALEAQKSDPLVVDPYAEAFCRA
MAV_4873|M.avium_104 ---MRSEGDTWDITTSVGSTALFVATARALEAQKPDPLAVDPYAEIFCRA
MMAR_0539|M.marinum_M ---MRSEGDSWDITTSVGSTALFVATARALEALKPDPLAVDPYAELFCRA
MSMEG_0614|M.smegmatis_MC2_155 ---MRTDNDQWDITISVGQTALFVAASRALEARKPHPLAVDHYAEVFCRA
MAB_0213c|M.abscessus_ATCC_199 ---MRTDTDTWDIQTSVGSTALAVAAGRALARHPANGAPIDPYAELFCRA
Mflv_0743|M.gilvum_PYR-GCK MSSLRTDDDTWDIASSVGATAVMVAAARAAETERHDALINDPYAKVLVEG
Mvan_0104|M.vanbaalenii_PYR-1 MSSLRTDNDTWDIASSVGATAVMVAAARAAETERPEPLIDDPYAKILVAG
TH_4502|M.thermoresistible__bu MSSLRTDDDTWDIATSVGSTAVMVAASRAAETEREDALIRDPYAKVLVAG
MLBr_02640|M.leprae_Br4923 ---MRTHDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRDPYAKLLVTN
MUL_4402|M.ulcerans_Agy99 --MPRTDNDSWTITESVGATALGVAAARAAETESENPLIEDPFARVFVDA
*:. * * * *** **: **:.** . * :*. :
Mb0289|M.bovis_AF2122/97 VGGS--WADVLD----GKLPDHKLKSTDFGEHFVNFQGARTKYFDEYFRR
Rv0281|M.tuberculosis_H37Rv VGGS--WADVLD----GKLPDHKLKSTDFGEHFVNFQGARTKYFDEYFRR
MAV_4873|M.avium_104 VGGS--AADVLD----GKDPDHQLKTDDFGVHFVNFQGARTKYFDEYFRR
MMAR_0539|M.marinum_M VGGS--WADVLD----GNAADHELQSDDFGKHFVNFQGARTKYFDAYFRR
MSMEG_0614|M.smegmatis_MC2_155 AGGD--WVAAVE----GTDPEHPLQT-EFGVDFVNFQGARTKYFDDYFRR
MAB_0213c|M.abscessus_ATCC_199 AGGQ--WSDLVQ----GKQSDHALSSEDFGRSFANFQAARTAFFDNFFTT
Mflv_0743|M.gilvum_PYR-GCK AGAG-AWRFIADEDLVAKASESDTEVGALFEHMKNYQAVRTHFFDAFFSA
Mvan_0104|M.vanbaalenii_PYR-1 AGNG-AWQYIADDGFVAKVTESDPEIGPLFEHMKNYQAVRTHFFDAFFAA
TH_4502|M.thermoresistible__bu AGTG-VWELILDDDFTAKIEAADPETAAIFDHMGNYQAVRTHFFDTYFAR
MLBr_02640|M.leprae_Br4923 TGAGALWEAMLDPSMVAKVEAIDAEAAAMVEHMRSYQAVRTNFFDTYFNN
MUL_4402|M.ulcerans_Agy99 AGDG-MWSMFANPALLAGAPEIESQVGARVRQMIDFMATRTAFFDEFFLG
.* : . . : .: ..** :** :*
Mb0289|M.bovis_AF2122/97 AAAAGARQVVILAAGLDSRAYRLPWPDGTTVFELDRPQVLDFKREVLASH
Rv0281|M.tuberculosis_H37Rv AAAAGARQVVILAAGLDSRAYRLPWPDGTTVFELDRPQVLDFKREVLASH
MAV_4873|M.avium_104 AADAGVRQVVILAAGLDSRAYRLDWPAATTIFELDQPQVLDFKREVLAGV
MMAR_0539|M.marinum_M AVEAGVRQVVVLAAGLDSRAYRLSWPDGTTIFELDRPQVLDFKREVLGGH
MSMEG_0614|M.smegmatis_MC2_155 VADAGVRQVVLLAAGLDSRAYRLPWADGTVVYELDVPKVLEFKREVLRRH
MAB_0213c|M.abscessus_ATCC_199 TSDTGVRQVVLLASGLDCRAYRLQWPAETEVYELDQPLVQQFKQETLDAH
Mflv_0743|M.gilvum_PYR-GCK AVDAGVRQIVILASGLDSRAFRLPWPAGTVVYEIDQPLVLDYKSSTLAAH
Mvan_0104|M.vanbaalenii_PYR-1 AVDAGIRQIVILASGLDSRAFRLPWPAGTTVFEIDQPLVLAYKSSTLASH
TH_4502|M.thermoresistible__bu AAEAGIRQVVILASGLDSRAYRLPWPDGTVVYEIDQPKVLEYKSATLAAH
MLBr_02640|M.leprae_Br4923 AVIDGIRQFVILASGLDSRAYRLDWPTGTTVYEIDQPKVLAYKSTTLAEH
MUL_4402|M.ulcerans_Agy99 AADAGVRQVVILASGLDSRAWRLPWPDGTVVYELDQPRVLEFKSATLRQH
. * **.*:**:***.**:** *. * ::*:* * * :* .*
Mb0289|M.bovis_AF2122/97 GAQPRALRREIAVDLRDDWPQALRDSGFDAAAPSAWIAEGLLIYLPATAQ
Rv0281|M.tuberculosis_H37Rv GAQPRALRREIAVDLRDDWPQALRDSGFDAAAPSAWIAEGLLIYLPATAQ
MAV_4873|M.avium_104 DAHPRAERREIAVDLREDWPQALRDSGFDPDKPSAWIAEGLLIYLPASAQ
MMAR_0539|M.marinum_M GVRPRTERREIAVDLRDDWPQALRDSGFDAEAPSAWIAEGLLIYLPAAAQ
MSMEG_0614|M.smegmatis_MC2_155 GATPTAERREVPVDLRDDWPAALRANGFDASQPSAWIAEGLLIYLPADAQ
MAB_0213c|M.abscessus_ATCC_199 GAAPSAVRHPISVDLRQDWSTILQESGFDPSRPSAWLVEGLLFFLKSSAQ
Mflv_0743|M.gilvum_PYR-GCK GVAPTAERREVPIDLRQDWPAALVATGFDPARPTAWLAEGLLMYLPADAQ
Mvan_0104|M.vanbaalenii_PYR-1 GVQPTADRREVPIDLRQDWPTALTHAGFDADQPTAWLAEGLLMYLPADAQ
TH_4502|M.thermoresistible__bu GVQPAADRREVAVDLRHDWPKALRAKGFDPQQRTAWLAEGLLMYLPADAQ
MLBr_02640|M.leprae_Br4923 GVTPTADRREVPIDLRQDWPPALRSAGFDPSARTAWLAEGLLMYLPATAQ
MUL_4402|M.ulcerans_Agy99 GARPTAQLMNIPIDLRQDWPAALLDSGFDASKPTAWSAEGLVRYLPARAQ
.. * : :.:***.**. * ***. :** .***: :* : **
Mb0289|M.bovis_AF2122/97 ERLFTGIDALAGRRSHVAVED-GAPMGPDEYAAKVEEERAAIAEGA----
Rv0281|M.tuberculosis_H37Rv ERLFTGIDALAGRRSHVAVED-GAPMGPDEYAAKVEEERAAIAEGA----
MAV_4873|M.avium_104 EQLFTGIDALAGHGSHVAVEE-GAPMTPEDFEAAVAAERAANEQG-----
MMAR_0539|M.marinum_M EQLFTGIDSLACLGSHVAVED-GAPLPDAEFAAKLEEERAAVAAG-----
MSMEG_0614|M.smegmatis_MC2_155 ELLFAGIDALSAPGSFVAIEE-SAPMPMDVFEVKRAEALAS---G-----
MAB_0213c|M.abscessus_ATCC_199 DLLLETIDSLAAPGSHIAVEQ-RDTYPDIEFEMRRAAAADSAEPGGS---
Mflv_0743|M.gilvum_PYR-GCK DRLFAQITELSAPGSQVAAES--MGVHAPDRRERMRERFASIASQID--I
Mvan_0104|M.vanbaalenii_PYR-1 DRLFAQITELSAPGSRVAAES--MGIHAQDRRERMRERFASITAQFD--V
TH_4502|M.thermoresistible__bu DRLFENITALSAPGSRLAVET--AAEEPVDRREQMRARMERIASQFG--L
MLBr_02640|M.leprae_Br4923 DGLFTEIGGLSAVGSRIAVET--SPLHGDEWREQMQLRFRRVSDALG--F
MUL_4402|M.ulcerans_Agy99 DLLFERIDTLSPAGSWLATNVPQGGFLDPDLVRRQHEEMQRMRAAAGRLV
: *: * *: * :* :
Mb0289|M.bovis_AF2122/97 -EEHPFFQLVYNE-RCAPAAEWFGERGWTAVATLLNDYLEAVGRPVP---
Rv0281|M.tuberculosis_H37Rv -EEHPFFQLVYNE-RCAPAAEWFGERGWTAVATLLNDYLEAVGRPVP---
MAV_4873|M.avium_104 -EQRMFFQLVYNE-QCAPAAEWFGSRGWTAVPTPLADYLRQVGRPVP---
MMAR_0539|M.marinum_M -GERPFFQLLYNE-RCAPAADWFSEHGWTALGTPLNNYLREVGRPVP---
MSMEG_0614|M.smegmatis_MC2_155 -DPNSFFALVFNE-QCAPGEQWFSERGWTASTTTLNECLHEVGRPAP---
MAB_0213c|M.abscessus_ATCC_199 -PLADFLALIYNE-SRSEAATWLRGRGWAAERIALLDYMNTSGFELP---
Mflv_0743|M.gilvum_PYR-GCK EP-MDITELTYEDPDRAEVAEWLAAHGWTAQAVPSQDAMRRLDRYV----
Mvan_0104|M.vanbaalenii_PYR-1 EP-MDITELTYEDPDRADVAQWLTAHGWRAEAVPSQDEMRRLHRLV----
TH_4502|M.thermoresistible__bu EKALDVAQLMYDDPDRADVPEWLTGHGWRTEWVSAPDEMRRLDRFVAAAM
MLBr_02640|M.leprae_Br4923 EQAVDVQELIYHDENRAVVADWLNRHGWRATAQSAPDEMRRVGRWG----
MUL_4402|M.ulcerans_Agy99 EIQMPAVEDLWYAEERTPVADWLGEHGWRASATTSAELLTRYGRPV----
: : *: :** : : :
Mb0289|M.bovis_AF2122/97 ----GPESEAGPMFARNTLVSAARV--
Rv0281|M.tuberculosis_H37Rv ----GPESEAGPMFARNTLVSAARV--
MAV_4873|M.avium_104 ----GPDTEAGPMIARNTLVSAVRA--
MMAR_0539|M.marinum_M ----GPGSEVAAMFARNTLMSATKP--
MSMEG_0614|M.smegmatis_MC2_155 ----APDSEAAQMTGSISLMWARKG--
MAB_0213c|M.abscessus_ATCC_199 ----AYSSVGWDTLRYTNMVTAAKR--
Mflv_0743|M.gilvum_PYR-GCK ------EVADSDGQSFSTFTTGTKL--
Mvan_0104|M.vanbaalenii_PYR-1 ------EIADGDDQSFSTFTTAVKR--
TH_4502|M.thermoresistible__bu PPGDDADAADLDDTAFSKFVTAERPS-
MLBr_02640|M.leprae_Br4923 ---DGVPMAD-DKDAFAEFVTAHRL--
MUL_4402|M.ulcerans_Agy99 ------PDDAEGPVPPTLFVSAHRPAA
: . :