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MTSQHDKPLAGRVAYITGAGRGQGRAHAIRLAADGADIVAIDTCDKPSPYNDYPATTSHEFDETISAVRD LGRDIITERVDVRDLAGHQKVIQEAITRFGRLDIVVANAGIASWARLWEIEADQWRDVIDVNLTGVWNTI KAAVPAMIEAGNGGSIITVSSSAGIKAMPGCGHYVAAKFGVVGLTNSLAIELGEYGIRVNSIHPYGTNTP LAGDQSVLRMFEMYPGYLQSFSQTLVDNDRLIEPAEIAEVVAWLAGDASGVMTGAQIPVDKGYLKR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0100 | - | - | 100% (276) | putative short chain dehydrogenase/reductase |
| M. abscessus ATCC 19977 | MAB_3844c | - | 3e-89 | 56.13% (269) | putative short-chain dehydrogenase/reductase |
| M. abscessus ATCC 19977 | MAB_0072c | - | 6e-54 | 42.70% (274) | putative short chain dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0706 | fabG | 9e-86 | 55.43% (267) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_5072 | fabG | 6e-87 | 56.32% (277) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. tuberculosis H37Rv | Rv0687 | fabG | 9e-86 | 55.43% (267) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01740 | - | 2e-26 | 34.48% (203) | short chain dehydrogenase |
| M. marinum M | MMAR_1016 | - | 6e-84 | 55.43% (267) | short-chain dehydrogenase/reductase |
| M. avium 104 | MAV_4486 | - | 1e-85 | 56.18% (267) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_1410 | fabG | 4e-87 | 54.87% (277) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. thermoresistible (build 8) | TH_3434 | - | 3e-86 | 56.25% (272) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0768 | - | 5e-74 | 53.44% (247) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_1286 | fabG | 1e-85 | 54.87% (277) | 3-ketoacyl-(acyl-carrier-protein) reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0706|M.bovis_AF2122/97 -MSARGGSLHGRVAFVTGAARAQGRSHAVRLAREGADIVALDICAPVSGS
Rv0687|M.tuberculosis_H37Rv -MSARGGSLHGRVAFVTGAARAQGRSHAVRLAREGADIVALDICAPVSGS
MAV_4486|M.avium_104 -MSGQAGSLQGRVAFITGAARGQGRSHAVRLAAEGADIIACDICAPVSAS
MMAR_1016|M.marinum_M -MAAQTGSLDGRVAFVTGAARAQGRSHAVRLAREGADIIAMDICGPVSET
MUL_0768|M.ulcerans_Agy99 ----------------------------MRLAREGADIIAMDICGPVSES
Mflv_5072|M.gilvum_PYR-GCK MPMSSGTPLEGRVALITGAARGQGRAHAIRLAADGADIVALDVCKPVSES
Mvan_1286|M.vanbaalenii_PYR-1 MPMASAAPLEGRVALITGAARGQGRAHAVRLAAEGADIIAIDVCGPVSES
MSMEG_1410|M.smegmatis_MC2_155 -MATVGKTLEGRVAFVTGAARGQGRAHAVRLADEGADIIAIDVCAPVDDT
TH_3434|M.thermoresistible__bu ------------VAFITGAARGQGRAHAIRLAEEGADIIAIDVCGPVSDT
MAB_0100|M.abscessus_ATCC_1997 MTSQHDKPLAGRVAYITGAGRGQGRAHAIRLAADGADIVAIDTCDKPSPY
MLBr_01740|M.leprae_Br4923 -MVKTAQYFVGKRCFVTGAASGIGRATALRLAAYGAELYLTDRH------
:*** **:: *
Mb0706|M.bovis_AF2122/97 VTYPPATSEDLGETVRAVEAEGRKVLAR-EVDIRDDAELRRLVADGVEQF
Rv0687|M.tuberculosis_H37Rv VTYPPATSEDLGETVRAVEAEGRKVLAR-EVDIRDDAELRRLVADGVEQF
MAV_4486|M.avium_104 VTYAPASPEDLDETARLVEDQGRKALTR-VLDVRDDAALRELVADGMEQF
MMAR_1016|M.marinum_M ITYAPATAADLSETIRAVESEGRKVLAR-QADVRDSAALQQLVADGVEEF
MUL_0768|M.ulcerans_Agy99 ITYAPATAADLSETIRAVESEGRKVLAR-QADVRDSAALQQLVADGVEEF
Mflv_5072|M.gilvum_PYR-GCK VTYPMPTSEDLAETVRLVEETGRKVLAR-EVDIRDLAAQQQLVADAVEQF
Mvan_1286|M.vanbaalenii_PYR-1 ITYSMPTSEDLAETVRLVEATGRKVLAR-EVDIRDLAAQQQVVADGVEQF
MSMEG_1410|M.smegmatis_MC2_155 ITYPSATPEDLAETVAAVEATGRKVLAR-EVDIRDLAAQQQVVADGVEQF
TH_3434|M.thermoresistible__bu ITYPPATEDDLAETVRAVEATGRKVLAR-TADIRDLAAQQQIVAEGMERF
MAB_0100|M.abscessus_ATCC_1997 NDYPATTSHEFDETISAVRDLGRDIITE-RVDVRDLAGHQKVIQEAITRF
MLBr_01740|M.leprae_Br4923 -------CDGLAQTVSEARALGAQVPEYRALDISDYDEVAAFGADIHARH
: :* .. * . *: * . : ..
Mb0706|M.bovis_AF2122/97 GRLDIVVANAGVLGWGRLWELTDEQWETVIGVNLTGTWRTLRATVPAMID
Rv0687|M.tuberculosis_H37Rv GRLDIVVANAGVLGWGRLWELTDEQWETVIGVNLTGTWRTLRATVPAMID
MAV_4486|M.avium_104 GRLDVVVANAGVLSWGRVWELTDEQWDTVIGVNLTGTWRTLRATVPAMIE
MMAR_1016|M.marinum_M GRLDVVVANAGVLGWGRLWELTDEQWDTVIGVNLSGTWRTLRAAVPAMIE
MUL_0768|M.ulcerans_Agy99 GRLDVMVANAGVFGWGRLWELTDEQWDTVIGVNLSGTWRTLRAAVPAMIE
Mflv_5072|M.gilvum_PYR-GCK GRLDIVVANAGVLSWGRIWEMSEDQWDTVVDVNLNGTWRTIRAAVPAMIE
Mvan_1286|M.vanbaalenii_PYR-1 GRLDIVVANAGVLSWGRIWEMSEEQWDTVVDVNLNGTWRTVRAAVPAMIE
MSMEG_1410|M.smegmatis_MC2_155 GRLDIVVANAGVLSWGRIFEMSPEQWDTVVDVNLNGTWRTIRAAVPAMIE
TH_3434|M.thermoresistible__bu GRLDIVVANAGVLSWGRLWEMSEEQWDTVIDVNLNGTWRTIRAVVPAMIE
MAB_0100|M.abscessus_ATCC_1997 GRLDIVVANAGIASWARLWEIEADQWRDVIDVNLTGVWNTIKAAVPAMIE
MLBr_01740|M.leprae_Br4923 PSMDIVMNIAGVSVWGTVDRLTHDQWSNVVAINLMGPIHIIETFVPAILA
:*::: **: *. : .: :** *: :** * . :.: ***::
Mb0706|M.bovis_AF2122/97 AGNGGSIVVVSSSAGLKATPGNGHYAASKHALVALTNTLAIELGEFGIRV
Rv0687|M.tuberculosis_H37Rv AGNGGSIVVVSSSAGLKATPGNGHYAASKHALVALTNTLAIELGEFGIRV
MAV_4486|M.avium_104 AGNGGSIVVVSSSAGLKATPGNGHYSASKHGLTALTNTLAIELGEYGIRV
MMAR_1016|M.marinum_M AGNGGSIIVVSSSAGLKATPGNGHYAASKHGLVALTNTLAIELGEYDIRV
MUL_0768|M.ulcerans_Agy99 AGNGGSIIVVSSSAGLKATPGNGHYAASKHGLVALTNTLAIELGEYDIGV
Mflv_5072|M.gilvum_PYR-GCK AGNGGSIIIVSSSAGLKATPGNAHYAASKHGLVALTNALALEAGEFGIRV
Mvan_1286|M.vanbaalenii_PYR-1 AGNGGSIVIVSSSAGLKATPGNAHYAASKHGLVALTNALAIEAGEFGIRV
MSMEG_1410|M.smegmatis_MC2_155 AGNGGSIIIVSSSAGLKATPGNGHYAASKHGLVALTNSLALEVGEYGIRV
TH_3434|M.thermoresistible__bu AGNGGSIIIVSSSAGLKATPGNGHYAASKHGLVALTNALAIEVGEYGIRV
MAB_0100|M.abscessus_ATCC_1997 AGNGGSIITVSSSAGIKAMPGCGHYVAAKFGVVGLTNSLAIELGEYGIRV
MLBr_01740|M.leprae_Br4923 AGRGGHLVNVSSAAGLVALPWHAAYSASKYGLRGLSEVLRFDLARYRIGV
**.** :: ***:**: * * . * *:*..: .*:: * :: ..: * *
Mb0706|M.bovis_AF2122/97 NSIHPYSVDTPMIEPEAMIQTFAKHP---GYVHSFPPMPLQPKG------
Rv0687|M.tuberculosis_H37Rv NSIHPYSVDTPMIEPEAMIQTFAKHP---GYVHSFPPMPLQPKG------
MAV_4486|M.avium_104 NSIHPYSVETPMIEPEAMMEIFARHP---SFVHSFPPMPVQPNG------
MMAR_1016|M.marinum_M NSIHPYSVETPMIEPDVMMQVFGEHP---RFLHSFPPMPLQYKG------
MUL_0768|M.ulcerans_Agy99 NSIHPYSVETPMIEPDVMMQVFGEHP---RFLHSFPPMPLQYKG------
Mflv_5072|M.gilvum_PYR-GCK NSIHPYSIDTPMIEKDAMMEIFSKYP---TFLHSFAPMPFKPVARDGKPG
Mvan_1286|M.vanbaalenii_PYR-1 NSIHPYSIDTPMIEKDAMMEIFSKYP---TYLHSFAPMPFKPVAREGKPG
MSMEG_1410|M.smegmatis_MC2_155 NSIHPYSIDTPMIEPEAMAQVFAKYP---NYLHSFAPMPYQPVG-EGAEG
TH_3434|M.thermoresistible__bu NSIHPYSIDTPMIERDAMMAVFAKHP---NYLHSFAPMPLHPVNREGDGG
MAB_0100|M.abscessus_ATCC_1997 NSIHPYGTNTPLAGDQSVLRMFEMYP---GYLQSFSQTLVDNDR------
MLBr_01740|M.leprae_Br4923 SVVVPGAVRTPLVDTIEIAGVDRQDPRFSRWVDRFRGHAVSAERAAEKIL
. : * . **: : * ::. *
Mb0706|M.bovis_AF2122/97 -----------------------------FMTPDEISDVVVWLAGDGSGA
Rv0687|M.tuberculosis_H37Rv -----------------------------FMTPDEISDVVVWLAGDGSGA
MAV_4486|M.avium_104 -----------------------------FMTADEVADVVAWLAGDGSGT
MMAR_1016|M.marinum_M -----------------------------LMTSEEVSDVVVWLAGDGSGT
MUL_0768|M.ulcerans_Agy99 -----------------------------LMTSEEVSDVVVWLAGDGSGT
Mflv_5072|M.gilvum_PYR-GCK L--------------------------QEFMTVEEVSDVVAWLAGDSSAT
Mvan_1286|M.vanbaalenii_PYR-1 L--------------------------QEFMTVEEVADVVAWLAGDASST
MSMEG_1410|M.smegmatis_MC2_155 L--------------------------STFMTPEEVSDVVAWLAGDGSAT
TH_3434|M.thermoresistible__bu R--------------------------QEFMTPEEVADVVAWLAGDGSAT
MAB_0100|M.abscessus_ATCC_1997 -----------------------------LIEPAEIAEVVAWLAGDASGV
MLBr_01740|M.leprae_Br4923 AGVAKNRYLIYTSHDIRVLYGFKRLAWWPYGVVMKQVNVVFTRALRPSPA
: :** * * .
Mb0706|M.bovis_AF2122/97 LSGNQIPVDKGALKY-----------
Rv0687|M.tuberculosis_H37Rv LSGNQIPVDKGALKY-----------
MAV_4486|M.avium_104 LTGTQIPVDKGALKY-----------
MMAR_1016|M.marinum_M LSGAQIPVDKGALKY-----------
MUL_0768|M.ulcerans_Agy99 LSGAQIPVDKGALKY-----------
Mflv_5072|M.gilvum_PYR-GCK ISGSQIAVDRGTMKY-----------
Mvan_1286|M.vanbaalenii_PYR-1 ISGSQIAVDRGTMKY-----------
MSMEG_1410|M.smegmatis_MC2_155 LSGSQIAVDRGVMKY-----------
TH_3434|M.thermoresistible__bu LSGSQIAVDRGVMKY-----------
MAB_0100|M.abscessus_ATCC_1997 MTGAQIPVDKGYLKR-----------
MLBr_01740|M.leprae_Br4923 TMRCVEPIKVGVYSQPRSGEGGKSGN
.:. * .