For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4614 | - | - | 100% (299) | putative Enoyl-CoA hydratase/isomerase |
| M. thermoresistible (build 8) | TH_2798 | - | 8e-22 | 33.63% (223) | PUTATIVE Enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_2728 | - | 1e-21 | 31.42% (226) | PUTATIVE Enoyl-CoA hydratase/isomerase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1507 | echA12 | 1e-21 | 32.64% (242) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4357 | - | 7e-25 | 30.93% (291) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv1935c | echA13 | 1e-21 | 29.84% (305) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_01241 | - | 4e-19 | 32.87% (216) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_2737c | - | 2e-20 | 29.49% (234) | enoyl-CoA hydratase |
| M. marinum M | MMAR_2863 | echA13 | 8e-23 | 32.95% (258) | enoyl-CoA hydratase EchA13 |
| M. avium 104 | MAV_0670 | - | 5e-22 | 32.67% (251) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_4846 | - | 4e-22 | 33.64% (220) | enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_1480 | echA12 | 4e-20 | 30.47% (233) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_4219 | - | 3e-22 | 32.30% (226) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1507|M.bovis_AF2122/97 --------MPHRCAAQVVAGYRSTVSLVLVEHPRPEIAQITLNRPERMNS
MUL_1480|M.ulcerans_Agy99 ------------------------MSLVLLEHPRPDIALVTLNRPERMNS
MAB_2737c|M.abscessus_ATCC_199 ------------------------MSFVLVDRPRPEIALVTLNRPERMNA
MLBr_01241|M.leprae_Br4923 ------MSQTDASCTIAELPYRSVTDLVVLDFPRPEVALITLNRPGRMNS
Rv1935c|M.tuberculosis_H37Rv MFVGRVGPVDRRSDGERSRRPREFEYIRYETIDDGRIAAITLDRPKQRNA
MMAR_2863|M.marinum_M MNVAGVSPVDRRSNGERAAP--DFTYVRYETIDDGRIATITLNRPKQRNA
MAV_0670|M.avium_104 MTLSEQAGAQP---GARPAE----ELVTYETLDEGRIARIWLNRPDAHNA
MSMEG_4846|M.smegmatis_MC2_155 ------------------------MYIDYGVAD--SIATITLNRPEAANA
Mvan_4219|M.vanbaalenii_PYR-1 ------------------------MYIDYDVTD--RIATITLNRPEAANA
TH_4614|M.thermoresistible__bu ----------VSADDRATGEFEVDESWVRYEVVEPHIAQITINRPDRRNA
Mflv_4357|M.gilvum_PYR-GCK ------------------MTTTDDDRVLFDVDRDTRIATITLNNPKQRNS
:* : ::.* *:
Mb1507|M.bovis_AF2122/97 MA-FDVMVPLKEALAQVSYDNSVRVVVLTGAGRGFSSGADHKSAGVVPHV
MUL_1480|M.ulcerans_Agy99 IA-FDVMVPLKEVLEEVSYDNSVRVVVLTGAGRGFSSGADHKSAGAVPNV
MAB_2737c|M.abscessus_ATCC_199 MA-FDVMLPFKQMLVDISHDNDVRAVVITGAGKGFCSGADQKSAGPIPHI
MLBr_01241|M.leprae_Br4923 MA-LDLMKSLKQVLKRITYDHSVRVVVLTGAGRGFCSGADQKFTAPVPQV
Rv1935c|M.tuberculosis_H37Rv QT-RGMLVELGAAFELAEADDTVRVVILRAAGPAFSAGHDLGSADDIRER
MMAR_2863|M.marinum_M QT-RGMLVELGAAFELAEADDTVRVVILRGEGPAFSAGHDLGSADDVRER
MAV_0670|M.avium_104 QS-RGLLVQLDEAFVRAEADDAVRVVILAARGKNFSAGHDLGSELALAER
MSMEG_4846|M.smegmatis_MC2_155 QN-PELLDELDAAWTRAAEDNEVKVIILRANGKHFSAGHDLRGGGEVPEK
Mvan_4219|M.vanbaalenii_PYR-1 QN-PELLDELDAAWTRAAEDNEVSVIVLRANGKHFSAGHDLRGGGPVPDK
TH_4614|M.thermoresistible__bu ILSPDMHVLFKAHLDRAEADDEVKVVILAAEGKDFSAGDDVRRLPVEQAG
Mflv_4357|M.gilvum_PYR-GCK YD-AAMRNLLARHLDEVAEDDDITVVLLRGAEGVFSTGADMNNAYGWYGP
: : *. : .::: . *.:* *
Mb1507|M.bovis_AF2122/97 EN----------------LTRPTYALRSMELLDDVILMLRRLHQPVIAAV
MUL_1480|M.ulcerans_Agy99 GG----------------LTRPTYALRSMELLDEVILMLRRLHQPVIAAV
MAB_2737c|M.abscessus_ATCC_199 GG----------------LTQPTIALRSMELLDEVILTLRRMHQPVIAAI
MLBr_01241|M.leprae_Br4923 EG----------------LTQPVRALRAMELLEEVILALRRLHQPVIAAI
Rv1935c|M.tuberculosis_H37Rv SPGPDQHPSYRCNGATFGGVESRN-RQEWHYYFENTKRWRNLRKITIAQV
MMAR_2863|M.marinum_M APGPDQHPTYQCNGGTYGGVESRN-RQEWHYYFENTKRWRNLRKITVAQV
MAV_0670|M.avium_104 QPGPGQHPTFRFNGATRDPIAEKTYLQEWHYFFQNTCRWRDLRKITIAQV
MSMEG_4846|M.smegmatis_MC2_155 IS------------------LEFIIQHEARRYLDYTLRWRNVPKPSIAAV
Mvan_4219|M.vanbaalenii_PYR-1 IT------------------LEFIIAHEAKRYLEYTLRWRNVPKPSIAAV
TH_4614|M.thermoresistible__bu LK-------------KGGKLPQTARMGNARRLHRHLTNWLEFPKTVIAAC
Mflv_4357|M.gilvum_PYR-GCK EDPAG------AGKPRKSRPSQRRRLTVDRKSFGFYHNLMGFPKVTVGEI
. . : :.
Mb1507|M.bovis_AF2122/97 NGPAIGGGLCLALAADIRVASSSAYFRAAG-INNGLTASELGLSYLLPRA
MUL_1480|M.ulcerans_Agy99 NGPAIGGGLCLALAADVRVAAASAYFRAAG-INNGLTASELGLSYLLPRA
MAB_2737c|M.abscessus_ATCC_199 NGAAIGGGLCLALACDVRVASQDAYFRAAG-INNGLTASELGLSYLLPRA
MLBr_01241|M.leprae_Br4923 NGPAIGGGLCLALAADVRVASTRAYFRAAG-INNGLSASELGLSYLLPRA
Rv1935c|M.tuberculosis_H37Rv HGAVLSAGLMLAWCCDLIVASEDTVFADVVGTRLGMCGVEY---FGHPWE
MMAR_2863|M.marinum_M HGTVLSAGLMLAWCCDLIVAADDTVFADVVGTRLGMCGVEY---FGHPWE
MAV_0670|M.avium_104 QGNAISAGLMLIWACDLIVAADNAKFSDVVGVRMGMPGVEY---YAHPWE
MSMEG_4846|M.smegmatis_MC2_155 QGRCISGGLLLCWPCDLILASDDALFSDPV-ALMGIGGVEY---HGHTWE
Mvan_4219|M.vanbaalenii_PYR-1 QGRCISGGLLLCWPCDLIVAADDAQFSDPV-VLMGIGGVEY---HGHTWE
TH_4614|M.thermoresistible__bu QGATLGAGMNLALAADILVVSDDMYLARPQ-ARIGFAGFST-AMPLVLLK
Mflv_4357|M.gilvum_PYR-GCK SGYALGGGFEMALMTDISVIARDTRIGMPA---TRFLGPALGSLHLFFHR
* :..*: : *: : : : : .
Mb1507|M.bovis_AF2122/97 IGSSRAFEIMLTGRDVSAEEAERIGLVSRQVPDEQLLDACYAIAARMAGF
MUL_1480|M.ulcerans_Agy99 IGSSRAFEIMLTGRDVTAEEAERIGLVSCRVPDGQLLDTCYAITARMAAF
MAB_2737c|M.abscessus_ATCC_199 IGTSRASDIMLTGRDVDADEAERIGLVSRKVASESLLEECYAIGERIAGF
MLBr_01241|M.leprae_Br4923 VGSSRAFEIMLSGRDVGAEEAEQIGLVSYRVSDDRLLDTCYSIAARMATF
Rv1935c|M.tuberculosis_H37Rv FGPRKTKELLLTGDCIGADEAHALGMVSKVFPADELATSTIEFARRIAKV
MMAR_2863|M.marinum_M FGPRKAKELLLTGDSIGADEAHALGMVSKVFPGEDLADSAIEFARRIAKL
MAV_0670|M.avium_104 FGPRKAKELLLTGDALDADEAYRLGMVSKVFPADELADKTLEFARRIAER
MSMEG_4846|M.smegmatis_MC2_155 LGPRKAKEILFTGRALTAEEAERTGMVNRVVARDELDAQTRELAEQIATM
Mvan_4219|M.vanbaalenii_PYR-1 LGPRKAKEILFTGRAMTAEEVAATGMVNRVVPRDQLDAETRTLAEQIAKM
TH_4614|M.thermoresistible__bu LGPNRGYEAMITGRKVRAAELKEWGVAASVVPADRLRDEALRYARAIAHH
Mflv_4357|M.gilvum_PYR-GCK LGPVQARRLLLTGDIIRAADVEHLGVFTETCDADAVTARARYWAEKAAKM
.*. : :::* : * : *: : *
Mb1507|M.bovis_AF2122/97 SRPGIELTKRTLWSGLDAA----SLEAHMQAEGLGQLFVRLLTAN---FE
MUL_1480|M.ulcerans_Agy99 SRPGIELTKRTLWSGLDAA----SLEGHMQAEGLGQLFVRLLTAN---FE
MAB_2737c|M.abscessus_ATCC_199 SRPGIELTKRTIWSGLDAA----SLESHMHQEGLGQLYVRLLTDN---FE
MLBr_01241|M.leprae_Br4923 SRSGTELTKRALWGGLDAA----SLDKHMQSESLAQLFIALHTSN---FE
Rv1935c|M.tuberculosis_H37Rv PTMAALLIKESVNQTVDAMGFSAALDGCFKIHQLNHAHWGEVTGGKLSYG
MMAR_2863|M.marinum_M PTMAALLIKESVNQTVDAMGFTTALDGCFKIHQLNHAHWAEVTGGKLCYG
MAV_0670|M.avium_104 PTMAALLIKDSVNAASDAMGFTEALRHAFHIHELGHAHWAAHNENRYPVG
MSMEG_4846|M.smegmatis_MC2_155 PPFALRQAKRAVNQTLDVQGFYAAIQSVFDIHQTGHGNALSVSG-----W
Mvan_4219|M.vanbaalenii_PYR-1 PPFALRQAKRAVNQTLDVQGFYAAIQSVFDVHQTGHGNALSVGG-----W
TH_4614|M.thermoresistible__bu SSDGLMVGKHALITFWNAVGMAQFGDWVPMGHSVFSNLVWRDDEFNFMKE
Mflv_4357|M.gilvum_PYR-GCK PADGVVIAKEAFRLVEQSQAYQGEEVASYLFHAYGTNLQFADGEFNFVKT
. . * :. : .
Mb1507|M.bovis_AF2122/97 EAVAARAEQRAPVFTDDT-------
MUL_1480|M.ulcerans_Agy99 EAVAARAEKRPAVFTDDK-------
MAB_2737c|M.abscessus_ATCC_199 EATAARKEKRPAEFRDKR-------
MLBr_01241|M.leprae_Br4923 EAAAPCTEKRPTVLVDARGCATSPG
Rv1935c|M.tuberculosis_H37Rv TVEYGLEDWRAAPQIRPAIKQRP--
MMAR_2863|M.marinum_M TVEYGLDDWRAAPEILPATKRRP--
MAV_0670|M.avium_104 -LPPDVEDWRNAKPTRLARRDTP--
MSMEG_4846|M.smegmatis_MC2_155 PVLVDIEEMKANIK-----------
Mvan_4219|M.vanbaalenii_PYR-1 PVLVNLEEMKANIK-----------
TH_4614|M.thermoresistible__bu RSVRGGREALAELERRYREWGFE--
Mflv_4357|M.gilvum_PYR-GCK RAQHGTKEAFRLRDEHFHVPEP---
: