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M. thermoresistible (build 8) TH_4557 (-)

annotation: acyl-CoA dehydrogenase domain protein
coordinates: 2880860 - 2881519
length: 220

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_4557 - - 100% (220) acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8) TH_3980 - 2e-31 39.52% (210) PUTATIVE acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8) TH_4038 - 7e-27 37.02% (208) PUTATIVE putative acyl-CoA dehydrogenase domain protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3593 fadE32 4e-21 35.29% (153) acyl-CoA dehydrogenase FADE32
M. gilvum PYR-GCK Mflv_4380 - 6e-89 74.19% (217) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv3563 fadE32 2e-20 35.29% (153) acyl-CoA dehydrogenase FADE32
M. leprae Br4923 MLBr_00737 fadE25 7e-15 26.88% (186) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_2496 - 3e-67 59.53% (215) acyl-CoA dehydrogenase
M. marinum M MMAR_3738 fadE18_2 4e-31 40.31% (191) acyl-CoA dehydrogenase FadE18_2
M. avium 104 MAV_1765 - 5e-29 38.74% (191) pimeloyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_2190 - 3e-91 75.58% (217) acyl-CoA dehydrogenase domain-containing protein
M. ulcerans Agy99 MUL_3682 fadE18_2 1e-30 39.79% (191) acyl-CoA dehydrogenase FadE18_2
M. vanbaalenii PYR-1 Mvan_1964 - 2e-90 75.58% (217) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3593|M.bovis_AF2122/97            --------MTMEFALNEQQRDFAASIDAALGAADLPGVVRAWAAGDVAPG
Rv3563|M.tuberculosis_H37Rv         --------MTMEFALNEQQRDFAASIDAALGAADLPGVVRAWAAGDVAPG
TH_4557|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2190|M.smegmatis_MC2_155      ----------MDFNLTKEQELLRDGLTKFLSSRYDLQTSRAAAKLGEGWQ
Mflv_4380|M.gilvum_PYR-GCK          ----------MDFTLNDEQELLRGGLTRFLATRYDLEKSRTAAKTGAGWQ
Mvan_1964|M.vanbaalenii_PYR-1       ----------MDFKLNDEQELLRSGLTRFLATRYDLEKSRAAAKTGLGWQ
MAB_2496|M.abscessus_ATCC_1997      ----------MDFSLTDEQQLLKHSISDFLSNRYALNTSRRAARSDIRWQ
MMAR_3738|M.marinum_M               ----------MDFQYSDEQTLLRDTTRDLLSRSYDAESRNKIIDTDLGWS
MUL_3682|M.ulcerans_Agy99           ----------MDFQYSDEQTLLRDTTRDLLSRSYDAESRNKIIDTDLGWS
MAV_1765|M.avium_104                ----------MDFQLSDEQALLRDTTRDLLSRSYDPESRNKVIGSELGWS
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAAD--VDQRARFP
                                                                                      

Mb3593|M.bovis_AF2122/97            RKVWQQLANLG-VTALGVAEKFDGLGASPVDLVVALERLGRWCVPGPVTE
Rv3563|M.tuberculosis_H37Rv         RKVWQQLANLG-VTALGVAEKFDGLGASPVDLVVALERLGRWCVPGPVTE
TH_4557|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2190|M.smegmatis_MC2_155      PDIWRGFAEELGILGATLPEESGGIGGGAVEAMVIAEALGHALVIEPFVD
Mflv_4380|M.gilvum_PYR-GCK          PEIWRAFAEELGILGAALPEENGGIGGGPVEMMLIAEALGHALVIEPYVD
Mvan_1964|M.vanbaalenii_PYR-1       PEIWRAFAEELGILGAALPEENGGIGGGPVEMMLIAEALGHALVVEPYVD
MAB_2496|M.abscessus_ATCC_1997      PQVWKSFAEELGILAAPLPEDRGGLGGGAEEVLVICEVLGRHLVVEPFIG
MMAR_3738|M.marinum_M               RDVWSQLADTG-ILGLGFEPAE----AGQIEIMLVMTEVGRRLAPEPIVH
MUL_3682|M.ulcerans_Agy99           RDVWSQLADTG-ILGLGFEPAE----AGQIEIMLVMTEVGRRLAPEPIVH
MAV_1765|M.avium_104                REVWSQLADTG-ILGLGFDPDE----SGQIEIMVVLTEIGRRLAPEPVLH
MLBr_00737|M.leprae_Br4923          EEALAALNASG-FNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIP
                                                                                      

Mb3593|M.bovis_AF2122/97            SIAVAP--ILLAH---DDRAERSHGLASGELIATVAMPPRVPRAVDADTA
Rv3563|M.tuberculosis_H37Rv         SIAVAP--ILLAH---DDQAERSHGLASGELIATVAMPPRVPRAVDADTA
TH_4557|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2190|M.smegmatis_MC2_155      TVVVAG--GLLQRAGGDAAQNVLEDLVGGAAVVAVAATEPTSGDNWYSVE
Mflv_4380|M.gilvum_PYR-GCK          TAVVAA--GLLRRAGGEIADALLEEIVAGSAIVSLAATEPTSGDFWQDVR
Mvan_1964|M.vanbaalenii_PYR-1       TAVVAA--GLLLRAGGDTATALLEEIVAGTAIVSLAATEPTSGEFWQDVT
MAB_2496|M.abscessus_ATCC_1997      TVVLGG--GLLRRSNAEVAGDLIGGIASGDVVTGFAALEPTSGQSFHSVQ
MMAR_3738|M.marinum_M               AALAPG--AIIAELGNDAQLQLLDEVAAGGRLLAFAHLEPGQRSPAATVS
MUL_3682|M.ulcerans_Agy99           AALAPG--AIIAELGNDAQLQLLDEVAAGGRLLAFAHLEPGQRSPAATVS
MAV_1765|M.avium_104                AALGPG--ALIAELGSAAQKELLDEVAAGQRLLAFAHLEPGQRKPTAEVG
MLBr_00737|M.leprae_Br4923          AVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMR
                                                                                      

Mb3593|M.bovis_AF2122/97            GLVLLAGD------------------------------------------
Rv3563|M.tuberculosis_H37Rv         GLVLLAGD------------------------------------------
TH_4557|M.thermoresistible__bu      -----------------------LASHLLVTARTSGNQRDAEGISLFLV-
MSMEG_2190|M.smegmatis_MC2_155      TTARRDGDEWVLDGSKIVVVNALFATHLLVTARTSGDTTDKDGISLFLV-
Mflv_4380|M.gilvum_PYR-GCK          TTAVRDGDEWVLSGEKIVSSATPLAGHVLVTARTTGERADTAGISLFLL-
Mvan_1964|M.vanbaalenii_PYR-1       TSATRDGDSWVLRGQKIVSASTPLASHVLVTARTSGERADAEGISLFLV-
MAB_2496|M.abscessus_ATCC_1997      TTARRDGPDWVLDGEKIVVSDAPLATHVIVSARTSGEVADTSGLTLFVVP
MMAR_3738|M.marinum_M               TRAVQQGDSWLLSGTKNPVLAGDCADTLVVSAALP-----DGGVGLFLV-
MUL_3682|M.ulcerans_Agy99           TRAVRQGDSWLLIGTKNPVLAGDCADTLVVSAALP-----DGGVGLFLV-
MAV_1765|M.avium_104                TKAARQGDPWTLSGQKNPVLAGDCADTLVVSAALP-----DGGTGLFLV-
MLBr_00737|M.leprae_Br4923          TRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDK-GANGISAFIVH
                                                                                      

Mb3593|M.bovis_AF2122/97            ---GSVTEGTPGDCHRSVDPSR--------RLYEVAASGQAWRAPKDVVA
Rv3563|M.tuberculosis_H37Rv         ---GSVTEGTPGDCHRSVDPSR--------RLYEVAASGQAWRAPKDVVA
TH_4557|M.thermoresistible__bu      -DMGAGHPGLALNSYRTIDDRRAADITLEGVRLPADALLGAAGQAWASLE
MSMEG_2190|M.smegmatis_MC2_155      -ETASAGSGFTAHHYRTVDDRRASDLEFDGLRLPASALLGPEGQAGPSLE
Mflv_4380|M.gilvum_PYR-GCK          -DIASAPSGVEVHHYRTVDDRRASDIVLDGVRLPATALLGAEGDAWPSLA
Mvan_1964|M.vanbaalenii_PYR-1       -ELGSAATDIELHHYRTVDDRRASDIVFDGLRLPSTALLGAEGGAWPSIA
MAB_2496|M.abscessus_ATCC_1997      FDPAAPAQGIEAHHYRTIDDHHASDLVISGLRVPDSARISEVDQAWPLIE
MMAR_3738|M.marinum_M               -DAGPEGGGVDKHPYPTFDSQRGAQIDLD---QAPAAPLGDAVDASAAIR
MUL_3682|M.ulcerans_Agy99           -NAGPEGGGVDKHPYPTFDSQRGAQINLD---QAPAAPLGDAVDASAAIR
MAV_1765|M.avium_104                -DAG----AVTRHPYRTFDGQRGAQIDLD---ATPAEPLGEATDASGGIE
MLBr_00737|M.leprae_Br4923          KDDEGFSIGPKEKKLG-IKGSPTTELYFDKCRIPGDRIIGEPGTGFKTAL
                                                .    ..                               

Mb3593|M.bovis_AF2122/97            RAYEFGALATAAQLVGAGQALLEAAVNYAKQRTQFGRAIGSYQAIKHKLA
Rv3563|M.tuberculosis_H37Rv         RAYEFGALATAAQLVGAGQALLEAAVNYAKQRTQFGRAIGSYQAIKHKLA
TH_4557|M.thermoresistible__bu      QARDEGATAICAEAVGGMRKVLDDTVEYSKQRHQFGQPIGSFQVLQHRMV
MSMEG_2190|M.smegmatis_MC2_155      LARDEGAAAVCAEAVGGMRKVLADTVEYCKQRQQFGQPIGSFQALQHRMV
Mflv_4380|M.gilvum_PYR-GCK          RARDEGAAAISAEAVGCMRKVLADTVEYCKQRQQFGQPIGSFQVLQHRMV
Mvan_1964|M.vanbaalenii_PYR-1       LARDEGAAAICAEAVGCMRKVLADTVEYCKQRQQFGQSIGSFQVLQHRMV
MAB_2496|M.abscessus_ATCC_1997      AALDEATAATVAEAVGMLRKVLADTVEYTKQRQQFGVAISNFQALQHRMV
MMAR_3738|M.marinum_M               NAITRIQSAMCAEAVGAMEEALRLTTDYLKTRKQFGVTLNKFQALTQRAA
MUL_3682|M.ulcerans_Agy99           NAIIRIQSAMCAEAVGAMEEALRLTTDYLKTRKQFGVTLSKFQALTQRAA
MAV_1765|M.avium_104                AAIIRIQSALCSEALGAMEESLRLTTDYLKTRKQFGVTLNKFQALTQRAA
MLBr_00737|M.leprae_Br4923          ATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLA
                                     :      :  :: :*  .  *  :  * * * *** .:..:* :    .

Mb3593|M.bovis_AF2122/97            DVHIAIELACPLVYGAAVSLEPR------DVSAAKAAASEAALLAARSAL
Rv3563|M.tuberculosis_H37Rv         DVHIAIELACPLVYGAAVSLEPR------DVSAAKAAASEAALLAARWAL
TH_4557|M.thermoresistible__bu      DMHMELQQAIAAVYLAVLNLTADAATRARAVSAAKATVGRAARFIGQNAV
MSMEG_2190|M.smegmatis_MC2_155      DMHMEVEQASAAMYLAVLNLDSDAVTRAKAVSAAKATVGRAARFVGQNAV
Mflv_4380|M.gilvum_PYR-GCK          DMYMEVEQAAAAALLATLKLDEDETTRARAVSAAKATVGRAAQFVGQQAV
Mvan_1964|M.vanbaalenii_PYR-1       DMYMEVEQSAAAVLLAVLKLDSDDVTRARAVSAAKATVGRAAQFVGQQAV
MAB_2496|M.abscessus_ATCC_1997      DMHIEVEQSVAASYLASLNLDG--PRRARAVSAAKATIARAARLVGQEAV
MMAR_3738|M.marinum_M               DMYVSLELARSMNFYAAMSIADG-NLDPLIASRSKLQIGRSGRHIAQESI
MUL_3682|M.ulcerans_Agy99           DMYVSLELARSMNFYAAMSIADG-NLDPLIASRSKLQIGRSGRHIAQESI
MAV_1765|M.avium_104                DMYVSLELARSMSLYAAMSIADG-NIDPVIASRAKLQIGRSGRHIAQESI
MLBr_00737|M.leprae_Br4923          DMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTDAV
                                    *: : :: :      *               : :*   .  .      ::

Mb3593|M.bovis_AF2122/97            QTHGAIGFTCEHDLSLWLLRVQALHSAWGTPQEHRRRVLEAL--------
Rv3563|M.tuberculosis_H37Rv         QTHGAIGFTCEHDLSLWLLRVQALHSAWGTPQEHRRRVLEAL--------
TH_4557|M.thermoresistible__bu      QLHGGMGMTEELAIGHYFKRLTAMQYEFGSTDHHLTRY--AQLTRS----
MSMEG_2190|M.smegmatis_MC2_155      QLHGGMGMTEELAIGHYFKRLTALQYEYGSTAAHVSRY--AELTRP----
Mflv_4380|M.gilvum_PYR-GCK          QLHGGMGMTEELAIGHYFKRLTALQFEFGSTDHHITRY--GRLTTP----
Mvan_1964|M.vanbaalenii_PYR-1       QLHGGMGMTEELAIGHYFKRLTALQFEFGSTDHHVTRY--ARLTNR----
MAB_2496|M.abscessus_ATCC_1997      QLHGGMGMTEELAIGHYFKRLTVIESEFGNRDFHTARYGIARSTQG----
MMAR_3738|M.marinum_M               QLHGGIGVTAEYPVGHYAARLTAIDHTLGSTQDQLRVLIDHIADYDLVRL
MUL_3682|M.ulcerans_Agy99           QLHGGIGVTAEYPVGHYAARLTAIDHTLGSTQDQLRVLIDHIADYDLVRL
MAV_1765|M.avium_104                QMHGGIGVTAEYPISHYAARLTAIEHTLGTSGEHLHNLIDHLGDYDLVRL
MLBr_00737|M.leprae_Br4923          QLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR------
                                    * .*. * * :  :  :       .   *.   :

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_4557	-	-	100% (220)	acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)	TH_3980	-	2e-31	39.52% (210)	PUTATIVE acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)	TH_4038	-	7e-27	37.02% (208)	PUTATIVE putative acyl-CoA dehydrogenase domain protein