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M. thermoresistible (build 8) TH_4320 (-)

annotation: -
coordinates: 1692048 - 1692980
length: 311

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4320--100% (311)-

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_4378-4e-4642.70% (267) hypothetical protein Mflv_4378
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_4780-6e-0727.89% (251) dehydrogenase
M. avium 104MAV_0875-3e-0827.71% (249) FAD binding domain-containing protein
M. smegmatis MC2 155MSMEG_2197-1e-5044.73% (275) hypothetical protein MSMEG_2197
M. ulcerans Agy99MUL_0349-2e-0627.60% (250) dehydrogenase
M. vanbaalenii PYR-1Mvan_1966-2e-4040.31% (258) hypothetical protein Mvan_1966

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4378|M.gilvum_PYR-GCK          MSVNDPEWDDEVDVVCTDTGLAALATAISATEEDGEVFLADPSR------
Mvan_1966|M.vanbaalenii_PYR-1       -MFCEPDWDDEVDVVCTDTGLAGLATAIAAVEQDGEVFLATAPSPT----
TH_4320|M.thermoresistible__bu      ----MLIWDDEVDVVCVGGGVAALAAAIAAVELGGEVYVAGPAHPP----
MSMEG_2197|M.smegmatis_MC2_155      ------MWDDELDVVCCGSGSGAFAAAIAAADADLDVEVACRPVTP----
MMAR_4780|M.marinum_M               -----MLWSQTFDVVVLGSGGAGLTAALSAAVAGATVAVFEKAPTVGGTT
MUL_0349|M.ulcerans_Agy99           ------MWSQTFDVVVLGSGGAGLTAALSAAVAGATVAVFEKAPTVGGTT
MAV_0875|M.avium_104                -----MSWDHEVDVVVLGSGGAGLTAALTAAVAGASVQVYEKAPTVGGTT
                                           *.. .***  . * ..:::*::*.  .  * :   .       

Mflv_4378|M.gilvum_PYR-GCK          --APRHGWFGLVRPDGEVDREDDETAAYLAELTADLDLTSLTR-------
Mvan_1966|M.vanbaalenii_PYR-1       --DADRGWFDHAG--------DEDTVEYLGQLTADLDVAGLRQ-------
TH_4320|M.thermoresistible__bu      --ADGPLPETLTDIWLGPDVTDAETIRYLRALSADLT-SVTLA-------
MSMEG_2197|M.smegmatis_MC2_155      --QG-----TSGSPWLGRGIEDSETREYLDELVADQDPSSRDS-------
MMAR_4780|M.marinum_M               AVSGGIAWIPAHQRSPDRDLTVDDALRYLRAQSLHSMDDALVETFVRTGA
MUL_0349|M.ulcerans_Agy99           AVSGGIAWIPAHQRSPDRDLTVDDALRYLRTQSLHSMDDALVETFVRTGA
MAV_0875|M.avium_104                AVSGGIVWIPAHNRCPDGELTAADALKYLRAQSLGSMDDELVETFVRTGP
                                                           ::  **                     

Mflv_4378|M.gilvum_PYR-GCK          -------QDAALPVRRAGAVVPVRRR-PIPAFEGRR---LRDWAARCIPS
Mvan_1966|M.vanbaalenii_PYR-1       -------LDPDLPVRLMSETTPARGR-MVPPFEGPR---LREWAAVCVPS
TH_4320|M.thermoresistible__bu      -------RDAVIPVREVVPPPPFDPRGQVEPFIGSR---LRDWAGQCLSS
MSMEG_2197|M.smegmatis_MC2_155      -------EHADIEIRAMRQLSPAAPRTPVETFHGAQ---LRDWAGQCLRS
MMAR_4780|M.marinum_M               AMLDFVEKHSGVRFEIAAGFPDYRPELPGGQPAGGRSLGPAAFEPSRLGE
MUL_0349|M.ulcerans_Agy99           AMLDFVEKHSGVRFEIAAGFPDYRPELPGGQPAGGRSLGPAAFEPSRLGE
MAV_0875|M.avium_104                AMLDFIEAHSGLHFEIATGFPDYRPELPGGRPSGGRSLSAVPFDLARLGE
                                            .. : ..          .       * :      :    : .

Mflv_4378|M.gilvum_PYR-GCK          PTGYLYTQVTDWTSTTMDCGDGELFKVLDIG--AVDVG-DDPIGAVTDWL
Mvan_1966|M.vanbaalenii_PYR-1       PSGYLYTQVTDWTSTTLDGGDGDLFKVTEIG--VMAPDPDDTVGSVHDWL
TH_4320|M.thermoresistible__bu      PYGLLHTRVSDRGMDTLHTPQAEIIEVKVVG--SWPAGPPPSGAGVAGWL
MSMEG_2197|M.smegmatis_MC2_155      PYGLLYTRLTERGGVPMETEAGEIIEANVLGSIDLPAG-AGAAAAVDGWM
MMAR_4780|M.marinum_M               WASRITSFPPDWSNVGFDAETRARLHAGVEE----SEDLCVAGTALVAGL
MUL_0349|M.ulcerans_Agy99           WASRITSFPPDWSNVGFDAETRARLHAGVEE----SEDLCVAGTALVAGL
MAV_0875|M.avium_104                WATRITSFPADWSNVGFDAETRARLHAAIDER---TGHLCVAGTALIAGL
                                        : :  .:     :.      :..              .  .:   :

Mflv_4378|M.gilvum_PYR-GCK          AGEAQDRGLHGVEVTRFEHLVFDEGVVAGAVFSTPDGPLAVRARHGILMG
Mvan_1966|M.vanbaalenii_PYR-1       SDEARDRDIFPNPVTRFERLVFEDGVVTGAVFGTESGPLTVRARHGVLIC
TH_4320|M.thermoresistible__bu      AAQAEDREIDVHRDDRLERVVFEEGEVVGVVLTTGRGPRAVRARHGVTLT
MSMEG_2197|M.smegmatis_MC2_155      RMQLRERDIPSDDDAALERIVFEEGEIVGVALATADGPRTVRVRHGIAVS
MMAR_4780|M.marinum_M               LQGLLDVGVTPRTDAAAEELVVEDGAVVGVRIAQSGRSISVRARRGVVLA
MUL_0349|M.ulcerans_Agy99           LQGLLDVGVTPRTDAAAEELVVEDGAVVGVRIAQSGRSISVRARRGVVLA
MAV_0875|M.avium_104                LKGLLDLGVTPRVNARAEELVAEDGEITGVRIASAEGRIGVRARRGVILG
                                         :  :        *.:* ::* :.*. :        **.*:*: : 

Mflv_4378|M.gilvum_PYR-GCK          PG------------TAVPAEASADSAAAGHG-VRVALVG-----------
Mvan_1966|M.vanbaalenii_PYR-1       R-------------NGIPARGASPPGFPGHAPLRVALVG-----------
TH_4320|M.thermoresistible__bu      PT------------VPVGDTPAELGLPHYQHEIRIGLVS-----------
MSMEG_2197|M.smegmatis_MC2_155      TE------------VPAAGR----RRMETAQTLRVALVG-----------
MMAR_4780|M.marinum_M               TGGFEWDPVLVRAFLRGPMHGAVSPPNNTGDGLRMAMARGAELANMGEAW
MUL_0349|M.ulcerans_Agy99           TGGFEWDPVLVRAFLRGPMHGAVSPPNNTGDGLRMAMARGAELANMGEAW
MAV_0875|M.avium_104                TGGFEWDPVLVQAFLRGPMHGAVSPPNNTGDGLRMAMAHGADLANMGEAW
                                                                    :*:.:.            

Mflv_4378|M.gilvum_PYR-GCK          --------------KEASRFGRVELLT-----------------------
Mvan_1966|M.vanbaalenii_PYR-1       --------------KEASRFGRVELLT-----------------------
TH_4320|M.thermoresistible__bu      --------------QTASRFGRLEVLTRA---------------------
MSMEG_2197|M.smegmatis_MC2_155      --------------RSASRFSRVELLT-----------------------
MMAR_4780|M.marinum_M               WVPIVQIPNDTIDGKQRSRSVRLERTRPRSIIVNPAGQRFVNEACDYNSM
MUL_0349|M.ulcerans_Agy99           WVPIVQIPNDTIDGKQRSRSVRLERTRPRSIIVNPAGQRFVNEACNYNSM
MAV_0875|M.avium_104                WVPIVQIPGDTIDGKPRSRSVRLERTRPRSIIVNAAGRRFVNEACDYNSM
                                                  :  **  *:*                          

Mflv_4378|M.gilvum_PYR-GCK          ----------ADAASD----------------------------PEA---
Mvan_1966|M.vanbaalenii_PYR-1       ----------SDSAVAQACPL----------------HSSRPAAPEVRTS
TH_4320|M.thermoresistible__bu      -----GGLPLRGHVADRRNPGPADRRAQDRRMATVTDLSRRRRKPHRYPP
MSMEG_2197|M.smegmatis_MC2_155      -------IPSAGHPDD---------------------LAQGNGAPHSHAR
MMAR_4780|M.marinum_M               AGAFHYLDPRGGYVNDHAWIVFDSAHLQRYGFLG---IEPGQPVPDWFCE
MUL_0349|M.ulcerans_Agy99           AGAFHYLDPRGGYVNDHAWIVFDSAHLQRYGFLG---IEPGQPVPDWFCE
MAV_0875|M.avium_104                AGAFHYLDPRGGYVNDRGWMVFDSVHLQRYGFLG---VEPGQPVPDWFCE
                                               .                                *.    

Mflv_4378|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1966|M.vanbaalenii_PYR-1       RS------------------------------------------------
TH_4320|M.thermoresistible__bu      AGE-----------------------------------------------
MSMEG_2197|M.smegmatis_MC2_155      RS------------------------------------------------
MMAR_4780|M.marinum_M               STDLTELATKTGIDADGLGRTIARWNHNVASGTDPDFGRGASAYDGYWGD
MUL_0349|M.ulcerans_Agy99           STDLTELATKTGIDADGLGRTIARWNHNVASGTDPDFGRGASAYDGYWGD
MAV_0875|M.avium_104                SADLAELAAKTGIDADGLTRTVENWNRYVAAGVDPDFGRGSSAYDGYWGD
                                                                                      

Mflv_4378|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1966|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4320|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2197|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_4780|M.marinum_M               DQATTLAGKTLGPIDSAPFYAVPIRVGAMGTKGGPRTDRDGRVRHVSGGS
MUL_0349|M.ulcerans_Agy99           DQATTLAGKTLGPIDSAPFYAVPIRVGAMGTKGGPRTDRDGRVRHVSGRS
MAV_0875|M.avium_104                DSATTQAGKTLGPIDTAPYYAVPVSIGAMGTKGGPRTDRDARVLHVGGEP
                                                                                      

Mflv_4378|M.gilvum_PYR-GCK          -------------------------------------------------
Mvan_1966|M.vanbaalenii_PYR-1       -------------------------------------------------
TH_4320|M.thermoresistible__bu      -------------------------------------------------
MSMEG_2197|M.smegmatis_MC2_155      -------------------------------------------------
MMAR_4780|M.marinum_M               VPGLFAAGNAMAGVTGRAYGGAGGTIGPAMVFGYRAGRAAATGESADAP
MUL_0349|M.ulcerans_Agy99           VPGLFTAGNAMAGVTGLAYGGAGGTIGPAMVFGYRAGRAVATGESADAP
MAV_0875|M.avium_104                IPGLFAAGNAMGGVTGRAYGGAGGTLGPAMVFGYRAGHAAATGKSVDLQ