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LFCEPDWDDEVDVVCTDTGLAGLATAIAAVEQDGEVFLATAPSPTDADRGWFDHAGDEDTVEYLGQLTAD LDVAGLRQLDPDLPVRLMSETTPARGRMVPPFEGPRLREWAAVCVPSPSGYLYTQVTDWTSTTLDGGDGD LFKVTEIGVMAPDPDDTVGSVHDWLSDEARDRDIFPNPVTRFERLVFEDGVVTGAVFGTESGPLTVRARH GVLICRNGIPARGASPPGFPGHAPLRVALVGKEASRFGRVELLTSDSAVAQACPLHSSRPAAPEVRTSRS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1966 | - | - | 100% (280) | hypothetical protein Mvan_1966 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4378 | - | 9e-80 | 58.49% (265) | hypothetical protein Mflv_4378 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4780 | - | 8e-06 | 29.02% (193) | dehydrogenase |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_2197 | - | 1e-39 | 37.74% (257) | hypothetical protein MSMEG_2197 |
| M. thermoresistible (build 8) | TH_4320 | - | 1e-40 | 40.31% (258) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0349 | - | 5e-06 | 29.02% (193) | dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1966|M.vanbaalenii_PYR-1 -MFCEPDWDDEVDVVCTDTGLAGLATAIAAVEQDGEVFLATAPSPT----
Mflv_4378|M.gilvum_PYR-GCK MSVNDPEWDDEVDVVCTDTGLAALATAISATEEDGEVFLADPSR------
MSMEG_2197|M.smegmatis_MC2_155 ------MWDDELDVVCCGSGSGAFAAAIAAADADLDVEVACRPVTP----
TH_4320|M.thermoresistible__bu ----MLIWDDEVDVVCVGGGVAALAAAIAAVELGGEVYVAGPAHPP----
MMAR_4780|M.marinum_M -----MLWSQTFDVVVLGSGGAGLTAALSAAVAGATVAVFEKAPTVGGTT
MUL_0349|M.ulcerans_Agy99 ------MWSQTFDVVVLGSGGAGLTAALSAAVAGATVAVFEKAPTVGGTT
*.: .*** . * ..:::*::*. . * : .
Mvan_1966|M.vanbaalenii_PYR-1 --DADRGWFDHAG--------DEDTVEYLGQLTADLDVAGLRQ-------
Mflv_4378|M.gilvum_PYR-GCK --APRHGWFGLVRPDGEVDREDDETAAYLAELTADLDLTSLTR-------
MSMEG_2197|M.smegmatis_MC2_155 --QG-----TSGSPWLGRGIEDSETREYLDELVADQDPSSRDS-------
TH_4320|M.thermoresistible__bu --ADGPLPETLTDIWLGPDVTDAETIRYLRALSADLT-SVTLA-------
MMAR_4780|M.marinum_M AVSGGIAWIPAHQRSPDRDLTVDDALRYLRAQSLHSMDDALVETFVRTGA
MUL_0349|M.ulcerans_Agy99 AVSGGIAWIPAHQRSPDRDLTVDDALRYLRTQSLHSMDDALVETFVRTGA
:: ** .
Mvan_1966|M.vanbaalenii_PYR-1 -------LDPDLPVRLMSETTPARGR-MVPPFEGPRLREWAAVCVPSPSG
Mflv_4378|M.gilvum_PYR-GCK -------QDAALPVRRAGAVVPVRRR-PIPAFEGRRLRDWAARCIPSPTG
MSMEG_2197|M.smegmatis_MC2_155 -------EHADIEIRAMRQLSPAAPRTPVETFHGAQLRDWAGQCLRSPYG
TH_4320|M.thermoresistible__bu -------RDAVIPVREVVPPPPFDPRGQVEPFIGSRLRDWAGQCLSSPYG
MMAR_4780|M.marinum_M AMLDFVEKHSGVRFEIAAGFPDYRPELPGGQPAGGRS-LGPAAFEPSRLG
MUL_0349|M.ulcerans_Agy99 AMLDFVEKHSGVRFEIAAGFPDYRPELPGGQPAGGRS-LGPAAFEPSRLG
.. : .. . * : .. * *
Mvan_1966|M.vanbaalenii_PYR-1 YLYTQVTDWTSTTLDGGDGDLFKVTEIG--VMAPDPDDTVGSVHDWLSDE
Mflv_4378|M.gilvum_PYR-GCK YLYTQVTDWTSTTMDCGDGELFKVLDIG--AVDVG-DDPIGAVTDWLAGE
MSMEG_2197|M.smegmatis_MC2_155 LLYTRLTERGGVPMETEAGEIIEANVLGSIDLPAG-AGAAAAVDGWMRMQ
TH_4320|M.thermoresistible__bu LLHTRVSDRGMDTLHTPQAEIIEVKVVG--SWPAGPPPSGAGVAGWLAAQ
MMAR_4780|M.marinum_M EWASRITSFPPDWSNVGFDAETRARLHAGVEESEDLCVAGTALVAGLLQG
MUL_0349|M.ulcerans_Agy99 EWASRITSFPPDWSNVGFDAETRARLHAGVEESEDLCVAGTALVAGLLQG
::::. . .. . . . .: :
Mvan_1966|M.vanbaalenii_PYR-1 ARDRDIFPNPVTRFERLVFEDGVVTGAVFGTESGPLTVRARHGVLICR--
Mflv_4378|M.gilvum_PYR-GCK AQDRGLHGVEVTRFEHLVFDEGVVAGAVFSTPDGPLAVRARHGILMGPG-
MSMEG_2197|M.smegmatis_MC2_155 LRERDIPSDDDAALERIVFEEGEIVGVALATADGPRTVRVRHGIAVSTE-
TH_4320|M.thermoresistible__bu AEDREIDVHRDDRLERVVFEEGEVVGVVLTTGRGPRAVRARHGVTLTPT-
MMAR_4780|M.marinum_M LLDVGVTPRTDAAAEELVVEDGAVVGVRIAQSGRSISVRARRGVVLATGG
MUL_0349|M.ulcerans_Agy99 LLDVGVTPRTDAAAEELVVEDGAVVGVRIAQSGRSISVRARRGVVLATGG
: : *.:*.::* :.*. : . :**.*:*: :
Mvan_1966|M.vanbaalenii_PYR-1 -----------NGIPARGASPPGFPGHAPLRVALVG--------------
Mflv_4378|M.gilvum_PYR-GCK -----------TAVPAEASADSAAAGHG-VRVALVG--------------
MSMEG_2197|M.smegmatis_MC2_155 -----------VPAAGR----RRMETAQTLRVALVG--------------
TH_4320|M.thermoresistible__bu -----------VPVGDTPAELGLPHYQHEIRIGLVS--------------
MMAR_4780|M.marinum_M FEWDPVLVRAFLRGPMHGAVSPPNNTGDGLRMAMARGAELANMGEAWWVP
MUL_0349|M.ulcerans_Agy99 FEWDPVLVRAFLRGPMHGAVSPPNNTGDGLRMAMARGAELANMGEAWWVP
:*:.:.
Mvan_1966|M.vanbaalenii_PYR-1 -----------KEASRFGRVELLT--------------------------
Mflv_4378|M.gilvum_PYR-GCK -----------KEASRFGRVELLT--------------------------
MSMEG_2197|M.smegmatis_MC2_155 -----------RSASRFSRVELLT--------------------------
TH_4320|M.thermoresistible__bu -----------QTASRFGRLEVLTRA------------------------
MMAR_4780|M.marinum_M IVQIPNDTIDGKQRSRSVRLERTRPRSIIVNPAGQRFVNEACDYNSMAGA
MUL_0349|M.ulcerans_Agy99 IVQIPNDTIDGKQRSRSVRLERTRPRSIIVNPAGQRFVNEACNYNSMAGA
: ** *:*
Mvan_1966|M.vanbaalenii_PYR-1 -------SDSAVAQACPL----------------HSSRPAAPEVRTSRS-
Mflv_4378|M.gilvum_PYR-GCK -------ADAASD----------------------------PEA------
MSMEG_2197|M.smegmatis_MC2_155 ----IPSAGHPDD---------------------LAQGNGAPHSHARRS-
TH_4320|M.thermoresistible__bu --GGLPLRGHVADRRNPGPADRRAQDRRMATVTDLSRRRRKPHRYPPAGE
MMAR_4780|M.marinum_M FHYLDPRGGYVNDHAWIVFDSAHLQRYGFLG---IEPGQPVPDWFCESTD
MUL_0349|M.ulcerans_Agy99 FHYLDPRGGYVNDHAWIVFDSAHLQRYGFLG---IEPGQPVPDWFCESTD
. *.
Mvan_1966|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4378|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2197|M.smegmatis_MC2_155 --------------------------------------------------
TH_4320|M.thermoresistible__bu --------------------------------------------------
MMAR_4780|M.marinum_M LTELATKTGIDADGLGRTIARWNHNVASGTDPDFGRGASAYDGYWGDDQA
MUL_0349|M.ulcerans_Agy99 LTELATKTGIDADGLGRTIARWNHNVASGTDPDFGRGASAYDGYWGDDQA
Mvan_1966|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4378|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2197|M.smegmatis_MC2_155 --------------------------------------------------
TH_4320|M.thermoresistible__bu --------------------------------------------------
MMAR_4780|M.marinum_M TTLAGKTLGPIDSAPFYAVPIRVGAMGTKGGPRTDRDGRVRHVSGGSVPG
MUL_0349|M.ulcerans_Agy99 TTLAGKTLGPIDSAPFYAVPIRVGAMGTKGGPRTDRDGRVRHVSGRSVPG
Mvan_1966|M.vanbaalenii_PYR-1 ----------------------------------------------
Mflv_4378|M.gilvum_PYR-GCK ----------------------------------------------
MSMEG_2197|M.smegmatis_MC2_155 ----------------------------------------------
TH_4320|M.thermoresistible__bu ----------------------------------------------
MMAR_4780|M.marinum_M LFAAGNAMAGVTGRAYGGAGGTIGPAMVFGYRAGRAAATGESADAP
MUL_0349|M.ulcerans_Agy99 LFTAGNAMAGVTGLAYGGAGGTIGPAMVFGYRAGRAVATGESADAP