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M. thermoresistible (build 8) TH_4296 (-)

annotation: putative protein of unknown function DUF690
coordinates: 2783378 - 2784793
length: 472

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4296--100% (472)putative protein of unknown function DUF690
M. thermoresistible (build 8)TH_3503-9e-5532.23% (484) PUTATIVE protein of unknown function DUF690
M. thermoresistible (build 8)TH_3098-4e-2739.60% (149) PUTATIVE protein of unknown function DUF690

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3480c-1e-10747.71% (480) hypothetical protein Mb3480c
M. gilvum PYR-GCKMflv_4962-1e-11350.11% (469) hypothetical protein Mflv_4962
M. tuberculosis H37RvRv3450c-1e-10747.71% (480) hypothetical protein Rv3450c
M. leprae Br4923MLBr_01544-1e-5832.93% (495) hypothetical protein MLBr_01544
M. abscessus ATCC 19977MAB_3759c-1e-11348.25% (487) hypothetical protein MAB_3759c
M. marinum MMMAR_1099-1e-10346.74% (475) hypothetical protein MMAR_1099
M. avium 104MAV_4392-1e-10246.47% (482) hypothetical protein MAV_4392
M. smegmatis MC2 155MSMEG_1534-1e-11048.73% (472) hypothetical protein MSMEG_1534
M. ulcerans Agy99MUL_0857-1e-10446.53% (475) hypothetical protein MUL_0857
M. vanbaalenii PYR-1Mvan_1444-1e-13756.69% (471) hypothetical protein Mvan_1444

CLUSTAL 2.0.9 multiple sequence alignment


Mb3480c|M.bovis_AF2122/97           ------------MPSPATTWLHVSGYRFLLRRIECALLFGDVCAATGALR
Rv3450c|M.tuberculosis_H37Rv        ------------MPSPATTWLHVSGYRFLLRRIECALLFGDVCAATGALR
MMAR_1099|M.marinum_M               ---MDAGDSRGWPPGRPTTWLQVSAYRFLVRRLECALLRGGLDPADGRPR
MUL_0857|M.ulcerans_Agy99           ---MDAGDSRGWPPGRPTTWLQVSAYRFLVRRLECALLRGGLDPADGRPR
MAV_4392|M.avium_104                ------------MPRRPTTWLQVSAYRYLSRRLECALLGQDPAAAGMRAR
Mflv_4962|M.gilvum_PYR-GCK          -------------MGQPVTRLQISGQRFLTRRMEHALVRADARMLDDPLR
Mvan_1444|M.vanbaalenii_PYR-1       -------------MRQPTTRLQVSGHRFLMRRMEHALVRGDARMLDDPLR
MSMEG_1534|M.smegmatis_MC2_155      ------------MARQPVTRLERSGRRFLIRRTMHALVRGDARMIDDPLR
TH_4296|M.thermoresistible__bu      -------------VGQPTTRLQVSGYRFMLRRMEHALVRADVRMLDDPLR
MAB_3759c|M.abscessus_ATCC_199      ------------MARQPTTRLQVSGYRFLVRRMEHALVRRDVRMIHDPMR
MLBr_01544|M.leprae_Br4923          MAEESSGRRGSEYGLGLSTRTQVTGYQFLARRTAMALTRWRVRMEVEPGR
                                                      *  . :. ::: **   **            *

Mb3480c|M.bovis_AF2122/97           ARTTSLALGCVLAIVAAMGCAFVALLRPQSALGQAPIVMGRESGALYVRV
Rv3450c|M.tuberculosis_H37Rv        ARTTSLALGCVLAIVAAMGCAFVALLRPQSALGQAPIVMGRESGALYVRV
MMAR_1099|M.marinum_M               ASAVSLAAGCVLSVVVLVGCVISALLRPQVGLGDAQIVVGRESGALYVRV
MUL_0857|M.ulcerans_Agy99           ASAVSLAAGCVLSVVVLVGCVISALLRPQVGLGDAQIVVGRESGALYVRV
MAV_4392|M.avium_104                GQPAALAAGAVLTAAALAAATLLGLLRPHVALDGARVVLARDSGALFVRV
Mflv_4962|M.gilvum_PYR-GCK          AQSLSLVVGAVLAAIAVAVCAVIAVVRPGGTLGDARIVVVRESGAMFVRL
Mvan_1444|M.vanbaalenii_PYR-1       GQSLSMTAGAVLAVIAVTVCAVLAFIRPGGELGDAPLVVVRESGAMYVRI
MSMEG_1534|M.smegmatis_MC2_155      AQSVSFAAGCIVTVLAAVVSAVLALVRPGDTLSDAPILLARNSGALHVRI
TH_4296|M.thermoresistible__bu      AQSLALTAGAVLAAVAVAGCAVLALLRPAGRLDSAQIVMERESGALYVRI
MAB_3759c|M.abscessus_ATCC_199      SQSSSLMVGIVLATVVVAGCAILAFFRPNMPLGDQPIVMGKDTGAVYVRI
MLBr_01544|M.leprae_Br4923          RQTLAVVASVSAALLGCLGALLWSFISPSGQLNESPIIIDRDSGALYVRV
                                      . :.  .   :      . . ... *   *.   ::: :::**:.**:

Mb3480c|M.bovis_AF2122/97           DDVWHPVLNLASARLIAATNANPQPVSESELGHTKRGPLLGIPGAPQLLD
Rv3450c|M.tuberculosis_H37Rv        DDVWHPVLNLASARLIAATNANPQPVSESELGHTKRGPLLGIPGAPQLLD
MMAR_1099|M.marinum_M               GDTWHPVLNLASARLIAGTGANPKPVREAEVIRAKRGPLLGIPGAPQFVG
MUL_0857|M.ulcerans_Agy99           GDTWHPVLNLASARLIAGTGANPKPVREAEVIRVKRGPLLGIPGAPQFVG
MAV_4392|M.avium_104                GDTWHPVLNLASARLIAASAVDPLTIRQADLDGSKRGPLLGIPGAPAFLG
Mflv_4962|M.gilvum_PYR-GCK          DDVLHPVYNLASARLLLGSPEVPRVVAQRAIDHAERGARLGIPAAPEQIP
Mvan_1444|M.vanbaalenii_PYR-1       DDTMHPVFNLASARLILGTAAEPRMVTQRAVDRAEIGPQVGIPGAPGQIS
MSMEG_1534|M.smegmatis_MC2_155      GDTVHPVLNLASARLIVQNPADPVLVDDAAIDAAPRGPLVGIPGAPARIH
TH_4296|M.thermoresistible__bu      DDTWHPTPNLASARLAARTAADPQPVSATALADAERGPMVGIPGAPGSIG
MAB_3759c|M.abscessus_ATCC_199      QDTLHPALNLASARLISGNNENPKPVKDSELAKARRGPLVGIPGAPASIP
MLBr_01544|M.leprae_Br4923          GDRLYPALNLASARLITGRPDNPHAVRSSQIATLPHGPLVGIPGAPSELS
                                     *  :*. *******       *  :    :     *. :***.**  : 

Mb3480c|M.bovis_AF2122/97           QPLAGAESAWAICDSD---------NGGSTTVVVGPAEDSSAQVLTAE-Q
Rv3450c|M.tuberculosis_H37Rv        QPLAGAESAWAICDSD---------NGGSTTVVVGPAEDSSAQVLTAE-Q
MMAR_1099|M.marinum_M               QSLPVQESAWTICDTD---------RGAATTLLVGRPAQQSVRRLVAE-Q
MUL_0857|M.ulcerans_Agy99           QSLPVQESAWTICDTD---------RGAATTLLVGRPAQQSVRRLVAE-Q
MAV_4392|M.avium_104                RPLAAADTAWSLCDSDG--------AGATTTILLGRPDAASMRVLGGG-Q
Mflv_4962|M.gilvum_PYR-GCK          TPLSADEAAWSVCDDD----------RGVTTVVAGPPATEGMTADR----
Mvan_1444|M.vanbaalenii_PYR-1       PPLQAAESGWTVCDE-----------RSGTTVTAGPVAGSAMTPGA----
MSMEG_1534|M.smegmatis_MC2_155      PPLSADEITWALCEDL---------ASESTTLIAGRSGLAPLRPGR----
TH_4296|M.thermoresistible__bu      RALPPGQSTWTLCDG-----------TTTTLWVGEPVAGDRLGDRRDDPD
MAB_3759c|M.abscessus_ATCC_199      GALTGDDTIWTVCDVATPPP----SSTVTTTVIAGKVTLENGNQEMPKDR
MLBr_01544|M.leprae_Br4923          PETP-QTSSWLVCDTVATSTGIGSSSGVTVTVIDGSPDLSGHRRVLTGSD
                                             * :*:               .                    

Mb3480c|M.bovis_AF2122/97           MILVATES--GSPTYLLYGGRRAVVDLADPAVVWALRLQGRVP---HVVA
Rv3450c|M.tuberculosis_H37Rv        MILVATES--GSPTYLLYGGRRAVVDLADPAVVWALRLQGRVP---HVVA
MMAR_1099|M.marinum_M               TILVATES--GSPAYLLYDGHRAVVDLADPAVRRALRLEGRTP---YRVS
MUL_0857|M.ulcerans_Agy99           TILVATES--GSPAYLLYDGHRAVVDLADPAVRRALRLEGRTP---YRVS
MAV_4392|M.avium_104                AMLVAAAA--GSPAYLLHDGHRARVDLADAAVVRTLRLEGRAP---RLVS
Mflv_4962|M.gilvum_PYR-GCK          HVLVTPRGQSAAVTYLLHGGRRSRVDLRHPAVVRALRLDGVVP---QPVS
Mvan_1444|M.vanbaalenii_PYR-1       SVLVTPRGGSAALTYLLHGRWRSRVDLRHPAVVRALRLDGVVP---QPVS
MSMEG_1534|M.smegmatis_MC2_155      AVPVAARG--AVTTYLLFDGRKAQVDLREGAVVRALRLEDVTP---VPVS
TH_4296|M.thermoresistible__bu      AVLVRSAG--GHGTYLLHDGARAAVDLRDTAVVRALRLENVEP---QSVS
MAB_3759c|M.abscessus_ATCC_199      YALVTVNS----QMYLLYDGKRAAVDLTNPAVTRALRLEGVTP---RPIS
MLBr_01544|M.leprae_Br4923          AVVLHYGG----DAWVIRQGRRSRIDAMNRSVLLPLGLTPEQVSQARPMS
                                       :   .      :::    :: :*  . :*  .* *          ::

Mb3480c|M.bovis_AF2122/97           QSLLNAVPEAPRITAPRIRGGGR-ASVGLPGFLVGGVVRITRASG-----
Rv3450c|M.tuberculosis_H37Rv        QSLLNAVPEAPRITAPRIRGGGR-ASVGLPGFLVGGVVRITRASG-----
MMAR_1099|M.marinum_M               RSLLSAVPEVPPISALRIGHAGEPALAGKLGFSVGTVLSITAGGG-----
MUL_0857|M.ulcerans_Agy99           RSLLSAVPEVPPISVLRIGHAGEPALAGKLGFSVGTVLSITAGGG-----
MAV_4392|M.avium_104                QSLLEAVPEAAPIAVPRIPGLGG-AAPGLPGFAIGTVLRIIRADG-----
Mflv_4962|M.gilvum_PYR-GCK          MELLAALPEAPAIEPPRIPGLGAPAPGALRNRTVGTVVTVAHAGTGSPRG
Mvan_1444|M.vanbaalenii_PYR-1       PALLAAVPEAPAISPPHIPALGSPGPSTLREHPVGTVVRAS--GTDAT--
MSMEG_1534|M.smegmatis_MC2_155      PTLLDSVPEAPAVRAPVIPDVGAPGPSAVNGLPVGSVVRVSRAVPDDSAR
TH_4296|M.thermoresistible__bu      DAVLEAIPESPPLTPPGIPAAGTPGPAPLSRIPVGTVVRLARASAAGGEV
MAB_3759c|M.abscessus_ATCC_199      MNVLNAIPEVPAIAPPPIPDAGAASPITTAGVRVGSVIKMSRADS-----
MLBr_01544|M.leprae_Br4923          RALFDALPVGPDLVVPDVPNEGNPASFPGAPGPVGTVIVTPQISGP----
                                      :: ::*  . :    :   *  .        :* *:            

Mb3480c|M.bovis_AF2122/97           -------DEYYVVLEDGVQRIGQVAADLLRFGDSQGSVNVPTVAPDVIRV
Rv3450c|M.tuberculosis_H37Rv        -------DEYYVVLEDGVQRIGQVAADLLRFGDSQGSVNVPTVAPDVIRV
MMAR_1099|M.marinum_M               -------AAYYVVLAQGVQRIGQVAADLLRFSDSQGAANAIAVAPDVIRA
MUL_0857|M.ulcerans_Agy99           -------AAYYVVLAQGVQRIGQVAADLLRFSDSQGAANAIAVAPDVIRA
MAV_4392|M.avium_104                -------DEYYAVLAGGVQRIGRVAADLLRLSNPQGGADAVTVAPDALRT
Mflv_4962|M.gilvum_PYR-GCK          A------GDHFVVLADGLQRIGEVTADLIRFTDARAGAEIPAVSADIVGA
Mvan_1444|M.vanbaalenii_PYR-1       -------AEYFVVLAEGLQRIGEVAADLIRYTDRRPGAEIPTVSADAVGA
MSMEG_1534|M.smegmatis_MC2_155      G------EEFFVVLTGGLQRVDRVVADLIRFTYPQPDGEPPLLAADVIAG
TH_4296|M.thermoresistible__bu      GPESGTESDYFVVLADGVQRVGRITADLIRFTTAQPHREIATVAAEVIAA
MAB_3759c|M.abscessus_ATCC_199      -------AEYYVVLAGGVQRINEVTADLIRFSDSQGAQEIVTVAPDVIAG
MLBr_01544|M.leprae_Br4923          -------QQYSLVLADGVETVSPLVAQIMQNAGKPGNTKLITVAPSVLVK
                                             .  **  *:: :. :.*::::        .   ::.. :  

Mb3480c|M.bovis_AF2122/97           APIVNTLPVSAFPDRPPTPVDGSPGRAVTTLCVTWTPAQPG---AARVAF
Rv3450c|M.tuberculosis_H37Rv        APIVNTLPVSAFPDRPPTPVDGSPGRAVTTLCVTWTPAQPG---AARVAF
MMAR_1099|M.marinum_M               APIVETLPVTGYPDTMSEPLDAG----ATTLCLSWVSGHAS---RPDVAF
MUL_0857|M.ulcerans_Agy99           APIVETLPVTGYPDTVSEPLDAG----VTTLCLSWVSRHAS---RPDVAF
MAV_4392|M.avium_104                APVVAALPVAGFPDRAPAVSEPA-----ATICAGWGDARS-------VAF
Mflv_4962|M.gilvum_PYR-GCK          LPVVTSLPVATYPDRADVTTASV-------VCATWAPTAGGH--GSRTEL
Mvan_1444|M.vanbaalenii_PYR-1       VPVVTTLPVTTFPDRGGVTAAPV-------ICAHWNQKNGET--TSHTSV
MSMEG_1534|M.smegmatis_MC2_155      VPHVETVAIPAVP-HGLSQRTRV-------LCAAWDPR------GNQTAL
TH_4296|M.thermoresistible__bu      VPAVDHLRVATFPDRIETRSAPV-------LCVQWDGADG----SPRTSL
MAB_3759c|M.abscessus_ATCC_199      HPSLNLLAVQTFPDRAGKIVDVP---EKSVLCSSWKPGQEKTQEHASTKL
MLBr_01544|M.leprae_Br4923          MPVVNKLDLSVYPDTPLQVVDLR---ENPSTCWWWERTAGES--RSRIQV
                                     * :  : :   *                  *  *              .

Mb3480c|M.bovis_AF2122/97           LAGSGPPVPLGGVP--VTLAQADGRGPALDAVYLPPGRSAYVAARSLSGG
Rv3450c|M.tuberculosis_H37Rv        LAGSGPPVPLGGVP--VTLAQADGRGPALDAVYLPPGRSAYVAARSLSGG
MMAR_1099|M.marinum_M               LAGDGLPVPAGARA--LPLVQADGRGPALDAVYLPPGRSAYVTSRGLSGS
MUL_0857|M.ulcerans_Agy99           LAGDGLPVPAGARA--LPLVQADGRGPALDAVYLPPGRSAYVTSRGLSGS
MAV_4392|M.avium_104                LTGAAVPVPPGRAP--VTLAQADGRGPALDAVYLPPGRSAYVRA------
Mflv_4962|M.gilvum_PYR-GCK          LTGPK--LPPAPRP--IVVAPGR-------EVAVPPGRSLYVRAVGLTGG
Mvan_1444|M.vanbaalenii_PYR-1       LVADS--APRRTRP--VTLVQTDGDGPAVDAVSVPAGRSVYVRSVSLTGA
MSMEG_1534|M.smegmatis_MC2_155      LFGEA--VGGAT----LELAQSDSAGPNIDNIGVPAGRSVLVEATGLAGG
TH_4296|M.thermoresistible__bu      LLRDS--APDGAR---VVLAQADGSGPAVDAVGMPGGRYAFVRATGLTGD
MAB_3759c|M.abscessus_ATCC_199      LMGSSLPLKTDQVP--VVLAQADKEGPNLDTAYIPPARSAFVRSTGLGGD
MLBr_01544|M.leprae_Br4923          ITGSTIPINSADVKKVVSLVKADTTGREADQVYFGSNYANFVAVTGNNPA
                                    :               : :.             .       *        

Mb3480c|M.bovis_AF2122/97           GT--GTRYLVTDTGVRFAIHD-DDVAHDLGLPTAAIPAPWPVLATLPSGP
Rv3450c|M.tuberculosis_H37Rv        GT--GTRYLVTDTGVRFAIHD-DDVAHDLGLPTAAIPAPWPVLATLPSGP
MMAR_1099|M.marinum_M               GAPLGRRYLVTDAGVRYLIRD-EDTARHLGLLTP-TAAPWPMLATLPEGP
MUL_0857|M.ulcerans_Agy99           GAPLGRRYLVTDAGVRYLIHD-EDTARHLGLLTP-TAAPWPMLATLPEGP
MAV_4392|M.avium_104                GANAGTRYLITDTGVRFAVPD-DDAAADLGLGQP-SPAPWPLLTLLPAGP
Mflv_4962|M.gilvum_PYR-GCK          DHSGGLLFLVTDAAIMFGIRD-ADAAAALGLVGAGVPAPWPVLATVPRGP
Mvan_1444|M.vanbaalenii_PYR-1       GHGTGSLFLVTDAGVLFGVRD-DESAAALGLTAPAVPAPWPVLATLPRGP
MSMEG_1534|M.smegmatis_MC2_155      ---RGPLYLLTDHGVLHGIQD-ADAARHLGLTGPAVPAPWAMLAMLPRGP
TH_4296|M.thermoresistible__bu      GGIAGSLFLLTDSGVVFGVHD-EEAAQWLGLPADARPAPWPMLARLPRGP
MAB_3759c|M.abscessus_ATCC_199      TGRAESLYLILDTGVRFGIGN-LEAAKALGLNVEPVPAPWPIVGLLPPGP
MLBr_01544|M.leprae_Br4923          AQTTESLWWVTRTGARFGVEDTKDVRDALGLNGTPNLAPWVALRLLSQGP
                                           : :   .  . : :  :    ***      ***  :  :. **

Mb3480c|M.bovis_AF2122/97           ELSRANASVARDTVAPGP-------------------------
Rv3450c|M.tuberculosis_H37Rv        ELSRANASVARDTVAPGP-------------------------
MMAR_1099|M.marinum_M               ELSGANASVAYDVVAVDPPVPAPGPATECPGGQCRQQPHQADR
MUL_0857|M.ulcerans_Agy99           ELSGASASVAYDVVAVDPPVPAPGPATECPGGQCPQQPHQADR
MAV_4392|M.avium_104                ELSRPNASVARDTVAGAP-------------------------
Mflv_4962|M.gilvum_PYR-GCK          ELSRDAATGR---------------------------------
Mvan_1444|M.vanbaalenii_PYR-1       ELGRDDASVLRDGTGAP--------------------------
MSMEG_1534|M.smegmatis_MC2_155      ELSSAAASVARDALPSTS-------------------------
TH_4296|M.thermoresistible__bu      ELGAQAASVSRDGAPPA--------------------------
MAB_3759c|M.abscessus_ATCC_199      RLSKEDALVVHDGMPPDKTGLAINPSTSATQAPS---------
MLBr_01544|M.leprae_Br4923          TLSRADALMEHDTLPMDMTPAELVVPK----------------
                                     *.   *