For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4290 | - | - | 100% (500) | putative pyruvate carboxylase |
| M. thermoresistible (build 8) | TH_1229 | pyc | 1e-35 | 29.01% (393) | pyruvate carboxylase |
| M. thermoresistible (build 8) | TH_0371 | - | 1e-06 | 27.19% (217) | PROBABLE 4-HYDROXY-2-OXOVALERATE ALDOLASE (HOA) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2991c | pca | 5e-37 | 29.52% (393) | pyruvate carboxylase |
| M. gilvum PYR-GCK | Mflv_4198 | - | 2e-36 | 28.89% (398) | pyruvate carboxylase |
| M. tuberculosis H37Rv | Rv2967c | pca | 5e-37 | 29.52% (393) | pyruvate carboxylase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3267c | - | 1e-34 | 27.43% (401) | pyruvate carboxylase |
| M. marinum M | MMAR_1749 | pca | 1e-35 | 28.68% (394) | pyruvate carboxylase Pca |
| M. avium 104 | MAV_0342 | pyc | 4e-34 | 28.17% (394) | pyruvate carboxylase |
| M. smegmatis MC2 155 | MSMEG_6648 | pyc | 2e-36 | 27.74% (483) | pyruvate carboxylase |
| M. ulcerans Agy99 | MUL_1992 | pca | 1e-35 | 28.68% (394) | pyruvate carboxylase |
| M. vanbaalenii PYR-1 | Mvan_2165 | - | 5e-38 | 28.97% (397) | pyruvate carboxylase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4198|M.gilvum_PYR-GCK MAG-QITKVLVANRGEIAIRAFRAAYEMGIATVAVYPYEDRNSLHRLKAD
Mvan_2165|M.vanbaalenii_PYR-1 MAG-QISKVLVANRGEIAIRAFRAAYEMGIATVAVYPYEDRNSLHRLKAD
MSMEG_6648|M.smegmatis_MC2_155 MSERAITKLLVANRGEIAIRAFRAAYELGISTVAVFAYEDRNSPHRLKAD
Mb2991c|M.bovis_AF2122/97 ----MFSKVLVANRGEIAIRAFRAAYELGVGTVAVYPYEDRNSQHRLKAD
Rv2967c|M.tuberculosis_H37Rv ----MFSKVLVANRGEIAIRAFRAAYELGVGTVAVYPYEDRNSQHRLKAD
MMAR_1749|M.marinum_M ----MISKVLVANRGEIAIRAFRAAYELGVGTVAVYAYEDRNSLHRSKAD
MUL_1992|M.ulcerans_Agy99 ----MISKVLVANRGEIAIRAFRAAYELGVGTVAVYAYEDRNSLHRTKAD
MAV_0342|M.avium_104 ----MLAKVLVANRGEIAIRAFRAAYELEMATVAVYPYEDRNSVHRLKAD
MAB_3267c|M.abscessus_ATCC_199 ----MFSKVLVANRGEIAIRAFRAAYELGAETVAVYPYEDRNSGHRLKAD
TH_4290|M.thermoresistible__bu --------------------------------------------------
Mflv_4198|M.gilvum_PYR-GCK ESYQIGDVGHPVRAYLSVDEIMRVALDAGCDAVYPGYGFLSENPELAAAC
Mvan_2165|M.vanbaalenii_PYR-1 ESYQIGEIGHPVRAYLSVAEIMRVAVEAGCDAVYPGYGFLSENPELAAAC
MSMEG_6648|M.smegmatis_MC2_155 EAYQIGETGHPVRAYLSVDEIIRVAKHSGADAIYPGYGFLSENPELAAAC
Mb2991c|M.bovis_AF2122/97 ESYQIGDIGHPVHAYLSVDEIVATARRAGADAIYPGYGFLSENPDLAAAC
Rv2967c|M.tuberculosis_H37Rv ESYQIGDIGHPVHAYLSVDEIVATARRAGADAIYPGYGFLSENPDLAAAC
MMAR_1749|M.marinum_M ESYQIGEVGHPVRAYLSVDEIVETALRAGADAIYPGYGFLSENPDLAGAC
MUL_1992|M.ulcerans_Agy99 ESYQIGEVGHPVRAYLSVDEIVETALRAGADAIYPGYGFLSENPDLAGAC
MAV_0342|M.avium_104 ESYQIGEEGHPVRAYLSVDEIVGTALACGADAIYPGYGFLSENPDLAAAC
MAB_3267c|M.abscessus_ATCC_199 EAYQIGEKGHPVRAYLSVSEVVNAARNAGADAIYPGYGFLSENPDLAAAC
TH_4290|M.thermoresistible__bu --------------------------------------------------
Mflv_4198|M.gilvum_PYR-GCK ASAGITFVGPSAHVLELTGNKARAIAAARSAGLPVLASSEPSASVEELVE
Mvan_2165|M.vanbaalenii_PYR-1 ADAGITFVGPSANVLELTGNKARAIQAARAAGLPVLTSSAPSASVDELVA
MSMEG_6648|M.smegmatis_MC2_155 HQAGIVFVGPRAHVLELTGNKFKAITAAREAGLPVLASSAPSANVAELVS
Mb2991c|M.bovis_AF2122/97 AAAGISFVGPSAEVLELAGNKSRAIAAAREAGLPVLMSSAPSASVDELLS
Rv2967c|M.tuberculosis_H37Rv AAAGISFVGPSAEVLELAGNKSRAIAAAREAGLPVLMSSAPSASVDELLS
MMAR_1749|M.marinum_M AAAGITFVGPRAELLQLTGNKSRAVTAAREAGLPVLRSSAPSASVQELVA
MUL_1992|M.ulcerans_Agy99 AAAGITFVGPRAELLQLTGNKSRAVTAAREAGLPVLRSSAPSASVQELVA
MAV_0342|M.avium_104 AAAGITFVGPSAEVLELTGDKSRAIAAARAAGLPVLASSPPSTSVQELLS
MAB_3267c|M.abscessus_ATCC_199 AEAGITFVGPPADVLELTGNKARAIAAAREAGLPVLASSEPSASVEELLA
TH_4290|M.thermoresistible__bu --------------------------------------------------
Mflv_4198|M.gilvum_PYR-GCK AART----MEFPLFVKAVSGGGGRGMRRVAEPEGLAEAVEAASREAESAF
Mvan_2165|M.vanbaalenii_PYR-1 AADG----MEFPLFVKAVSGGGGRGMRRVTDRAALAEAVEAASREAESAF
MSMEG_6648|M.smegmatis_MC2_155 AAEA----MDFPLFVKAVSGGGGRGMRRVTEPAALAESIEAASREAESAF
Mb2991c|M.bovis_AF2122/97 VAA----GMPFPLFVKAVAGGGGRGMRRVGDIAALPEAIEAASREAESAF
Rv2967c|M.tuberculosis_H37Rv VAA----GMPFPLFVKAVAGGGGRGMRRVGDIAALPEAIEAASREAESAF
MMAR_1749|M.marinum_M AAQSETTGLRFPLFVKAVAGGGGRGMRRVNDISALAEAIEAASREAESAF
MUL_1992|M.ulcerans_Agy99 AAQSETTGLRFPLFVKAVAGGGGRGMRRVNDISALAEAIEAASREAESAF
MAV_0342|M.avium_104 AAET----MTFPLFVKAVAGGGGRGMRRVTDPGALAEAIEAASREAESAF
MAB_3267c|M.abscessus_ATCC_199 AAES----MEFPVFVKAVAGGGGRGMRRVAERDQLREAIEAASREAESAF
TH_4290|M.thermoresistible__bu --------------------------------------------------
Mflv_4198|M.gilvum_PYR-GCK GDPSVYLEQAVLNPRHIEVQILADSRGNVMHLFERDCSVQRRHQKVIELA
Mvan_2165|M.vanbaalenii_PYR-1 GDPNVYLEQAVLNPRHIEVQILADTAGHVMHLFERDCSVQRRHQKVIELA
MSMEG_6648|M.smegmatis_MC2_155 GDPMVYLEQAVLNPRHIEVQVLADRTGEIIHLFERDCSMQRRHQKVIELA
Mb2991c|M.bovis_AF2122/97 GDPTVYLEQAVINPRHIEVQILADNLGDVIHLYERDCSVQRRHQKVIELA
Rv2967c|M.tuberculosis_H37Rv GDPTVYLEQAVINPRHIEVQILADNLGDVIHLYERDCSVQRRHQKVIELA
MMAR_1749|M.marinum_M GDPTVYLEQAVLNPRHIEVQILADTQGNVIHLYERDCSVQRRHQKVIELA
MUL_1992|M.ulcerans_Agy99 GDPTVYLEQAVLNPRHIEVQILADTQGNVIHLYERDCSVQRRHQKVIELA
MAV_0342|M.avium_104 GDASVFLEQAVINPRHIEVQILADTHGNVMHLYERDCSVQRRHQKVIEIA
MAB_3267c|M.abscessus_ATCC_199 GDPTVFLEQAVINPRHIEVQILADTAGNVIHLYERDCSVQRRHQKVIELA
TH_4290|M.thermoresistible__bu --------------------------------------------------
Mflv_4198|M.gilvum_PYR-GCK PAPNLPEELRQQICADAVAYAREIGYTCAGTVEFLLDERGHHVFIECNPR
Mvan_2165|M.vanbaalenii_PYR-1 PAPNLPDELRQKICDDAVAFAKEIDYSCAGTVEFLLDERGHHVFIECNPR
MSMEG_6648|M.smegmatis_MC2_155 PAPNLSDTQRQRICADAVSFARQIDYFCAGTVEFLLDERGHHVFIECNPR
Mb2991c|M.bovis_AF2122/97 PAPHLDAELRYKMCVDAVAFARHIGYSCAGTVEFLLDERGEYVFIEMNPR
Rv2967c|M.tuberculosis_H37Rv PAPHLDAELRYKMCVDAVAFARHIGYSCAGTVEFLLDERGEYVFIEMNPR
MMAR_1749|M.marinum_M PAPNLPGELRDKICADAVAFARHIGYTCAGTVEFLLDQSGEYVFIEMNPR
MUL_1992|M.ulcerans_Agy99 PAPNLPGELRDKICADAVAFARHIGYTCAGTVEFLLDQSGEYVFIEMNPR
MAV_0342|M.avium_104 PAPNLDPALRERICADAVAFARSIGYTCAGTVEFLLDERGNHVFIEMNPR
MAB_3267c|M.abscessus_ATCC_199 PAPNLPPELREKICSDAVAFARHIGYSCAGTVEFLLDERGHHVFIEMNPR
TH_4290|M.thermoresistible__bu --------------------------------------------------
Mflv_4198|M.gilvum_PYR-GCK IQVEHTVTEEITDVDLVASQIRIASGQTLADLGLSQEDLVIRGAAMQCRI
Mvan_2165|M.vanbaalenii_PYR-1 IQVEHTVTEEITDVDLVSSQLRIASGETLADLGLSQETLVIRGAALQCRI
MSMEG_6648|M.smegmatis_MC2_155 IQVEHTVTEEITDVDLVASQLRLASGETLGDLGLSQDAVRIRGTAMQCRI
Mb2991c|M.bovis_AF2122/97 VQVEHTVTEEITDVDLVASQLRIAAGETLEQLGLRQEDIAPHGAALQCRI
Rv2967c|M.tuberculosis_H37Rv VQVEHTVTEEITDVDLVASQLRIAAGETLEQLGLRQEDIAPHGAALQCRI
MMAR_1749|M.marinum_M IQVEHTVTEEITDVDLVSSQMRIAAGESLEDLGLRQETVRPHGAALQCRI
MUL_1992|M.ulcerans_Agy99 IQVEHTVTEEITDVDLVSSQMRIAAGESLEDLGLRQETVRPHGAALQCRI
MAV_0342|M.avium_104 IQVEHTVTEEITDVDLVSAQLRIASGQTLEEIGLSQDSVISRGAALQCRI
MAB_3267c|M.abscessus_ATCC_199 IQVEHTVTEEITDVDLVASQLRIASGETLDDLGLHQDSITPRGAALQCRI
TH_4290|M.thermoresistible__bu --------------------------------------------------
Mflv_4198|M.gilvum_PYR-GCK TTEDPANGFRPDTGRITAYRSPGGAGIRLDGGAVLGGEIGAHFDSMLVKL
Mvan_2165|M.vanbaalenii_PYR-1 TTEDPANGFRPDTGRITAYRSPGGAGIRLDGGAHLGAEIGAHFDSMLVKL
MSMEG_6648|M.smegmatis_MC2_155 TTEDPANGFRPDTGRVTAYRSPGGAGVRLDGGTHTGAEISAHFDSMLVKL
Mb2991c|M.bovis_AF2122/97 TTEDPANGFRPDTGRISALRTAGGAGVRLDGSTNLGAEISPYFDSMLVKL
Rv2967c|M.tuberculosis_H37Rv TTEDPANGFRPDTGRISALRTAGGAGVRLDGSTNLGAEISPYFDSMLVKL
MMAR_1749|M.marinum_M TTEDPTNGFRPDTGRISALRAPGGAGIRLDGSTNLGAEISAHFDSMLVKL
MUL_1992|M.ulcerans_Agy99 TTEDPTNGFRPDTGRISALRAPGGAGIRLDGSTNLGAEISAHFDSMLVKL
MAV_0342|M.avium_104 TTEDPANGFRPDTGRITAYRTPGGAGIRLDGGTTLGAEISAHFDSMLIKL
MAB_3267c|M.abscessus_ATCC_199 TTEDPANGFRPDTGRITAYRSPGGAGIRLDGGTTLGAEVGAHFDSMLVKL
TH_4290|M.thermoresistible__bu --------------------------------------------------
Mflv_4198|M.gilvum_PYR-GCK TCRGRDFATAAARAHRALAEFRVRGVSTNIPFLQAVIDDPDFRAGRVTTS
Mvan_2165|M.vanbaalenii_PYR-1 TCRGRDFATAVARAHRALAEFRVRGVSTNIPFLQAVIDDPDFRAGRVNTS
MSMEG_6648|M.smegmatis_MC2_155 TCRGQDFTGSAARARRALAEFRIRGVATNIGFLLAVLDDPDFRAGRVTTS
Mb2991c|M.bovis_AF2122/97 TCRGRDLPTAVSRARRAIAEFRIRGVSTNIPFLQAVLDDPDFRAGRVTTS
Rv2967c|M.tuberculosis_H37Rv TCRGRDLPTAVSRARRAIAEFRIRGVSTNIPFLQAVLDDPDFRAGRVTTS
MMAR_1749|M.marinum_M TCRGRDFSTAVNRARRAIAEFRIRGVSTNIPFLQAVLDDPDFQAGRITTA
MUL_1992|M.ulcerans_Agy99 TCRGRDLSTAVNRARRAIAEFRIRGVSTNIPFLQAVLDDPDFQAGRITTA
MAV_0342|M.avium_104 TCRGRDFPTAVRRARRAVAEFRIRGVSTNIPFLQAVLDDPDFQAGRITTS
MAB_3267c|M.abscessus_ATCC_199 TCRGRDFQTAVARARRAVAEFRIRGVATNIPFLQAVLDDPDFRAGHVTTS
TH_4290|M.thermoresistible__bu -----------------------------------------------VTS
*:
Mflv_4198|M.gilvum_PYR-GCK FIDERPGLLTSHTPADRGTKILNYLADVTVNQPHGPRPSTVYPQDKLPQI
Mvan_2165|M.vanbaalenii_PYR-1 FIDDRPYLLTSRSPADRGTKILNYLADVTVNQPHGPRPSTVYPHDKLPQI
MSMEG_6648|M.smegmatis_MC2_155 FIDERPHLLAAHTPADRGSRILNYLADVTVNKPHGERPSAVYPHDKLPAI
Mb2991c|M.bovis_AF2122/97 FIDERPQLLTARASADRGTKILNFLADVTVNNPYGSRPSTIYPDDKLPDL
Rv2967c|M.tuberculosis_H37Rv FIDERPQLLTARASADRGTKILNFLADVTVNNPYGSRPSTIYPDDKLPDL
MMAR_1749|M.marinum_M FIDERPQLLTARTSADRGTKILNYLADVTVNKPHGSRPSKVYPNDKLPQV
MUL_1992|M.ulcerans_Agy99 FIDERPQLLTARTSADRGTKILNYLADVTVNKPYGSRPSKVYPNDKLPQV
MAV_0342|M.avium_104 FIEQRPQLLTARSSADRGTKILNYLADVTVNKPHGERPSAVYPHDKLPDI
MAB_3267c|M.abscessus_ATCC_199 FIEERPQLLTARSSADRGTKILNYLADVTVNKPHGAKPSTVYPHDKLPPI
TH_4290|M.thermoresistible__bu YLDCADRAVGGR--------------------------------------
::: : .:
Mflv_4198|M.gilvum_PYR-GCK DLNTMPPRGSKHLLSEVGPEGFARWMRESKAVGVTDTTFRDAHQSLLATR
Mvan_2165|M.vanbaalenii_PYR-1 DLDAMPPRGSKHLLSEVGPEAFARWMRESKSVGVTDTTFRDAHQSLLATR
MSMEG_6648|M.smegmatis_MC2_155 DLSEPPPPGTRQRLESLGPQGFSDWLRDSPAVGVTDTTFRDAHQSLLATR
Mb2991c|M.bovis_AF2122/97 DLRAAPPAGSKQRLVKLGPEGFARWLRESAAVGVTDTTFRDAHQSLLATR
Rv2967c|M.tuberculosis_H37Rv DLRAAPPAGSKQRLVKLGPEGFARWLRESAAVGVTDTTFRDAHQSLLATR
MMAR_1749|M.marinum_M DLDAPPPAGSKQRLVELGPEGFARWLRESPAVGVTDTTFRDAHQSLLATR
MUL_1992|M.ulcerans_Agy99 DLDAPPPAGSKQRLVELGPEGFARWLRESPAVGVTDTTFRDAHQSLLATR
MAV_0342|M.avium_104 DLAASPPAGSKQRLTELGPERFAAWLRESGGVGVTDTTFRDAHQSLLATR
MAB_3267c|M.abscessus_ATCC_199 DLSVPPPDGSRQRLLALGPEGFAKALREQKAVGLTDTTFRDAHQSLLATR
TH_4290|M.thermoresistible__bu -----------------------------RTIQIIDQTLRDGPQSWWGMR
: : * *:**. ** . *
Mflv_4198|M.gilvum_PYR-GCK IRTSGMLMVAPYVARMTPQLLSIECWGGATYDVALRFLKEDPWERLAALR
Mvan_2165|M.vanbaalenii_PYR-1 IRTSGLLMVAPYIARMTPQLLSIECWGGATYDVALRFLKEDPWERLAALR
MSMEG_6648|M.smegmatis_MC2_155 VRTSGLVTVAPYIARMMPELLSIECWGGATYDVALRFLKEDPWERLAVLR
Mb2991c|M.bovis_AF2122/97 VRTSGLSRVAPYLARTMPQLLSVECWGGATYDVALRFLKEDPWERLATLR
Rv2967c|M.tuberculosis_H37Rv VRTSGLSRVAPYLARTMPQLLSVECWGGATYDVALRFLKEDPWERLATLR
MMAR_1749|M.marinum_M LRTSGLSRVAPYLARTMPQLLSVECWGGATYDVALRFLKEDPWERLATLR
MUL_1992|M.ulcerans_Agy99 LRTSGLSRVAPYLARTMPQLLSVECWGGATYDVALRFLKEDPWERLATLR
MAV_0342|M.avium_104 VRTSGLLKVAPYIARTMPQLLSVECWGGATYDVALRFLKEDPWERLTALR
MAB_3267c|M.abscessus_ATCC_199 VRTTGLLAVAPYVARLTPELLSIEAWGGATYDVALRFLKEDPWERLADLR
TH_4290|M.thermoresistible__bu MRKSMGLPIAGELDRTG--FNAIDLVGSSIFEVLVRHCKEDPWDQLISLS
:*.: :* : * : ::: *.: ::* :*. *****::* *
Mflv_4198|M.gilvum_PYR-GCK EAVPNICLQMLLRGRNTVGYTPYPESVTHAFVQEATATGIDIYRIFDALN
Mvan_2165|M.vanbaalenii_PYR-1 EAVPNICLQMLLRGRNTVGYTPYPESVTHAFVQEATATGVDIYRIFDALN
MSMEG_6648|M.smegmatis_MC2_155 EAAPNICLQMLLRGRNTVGYTPYPESVTDAFVAEATATGIDIFRIFDALN
Mb2991c|M.bovis_AF2122/97 AAMPNICLQMLLRGRNTVGYTPYPEIVTSAFVQEATATGIDIFRIFDALN
Rv2967c|M.tuberculosis_H37Rv AAMPNICLQMLLRGRNTVGYTPYPEIVTSAFVQEATATGIDIFRIFDALN
MMAR_1749|M.marinum_M AAMPNICLQMLLRGRNTVGYTPYPEVVTSSFIEEATATGIDIFRIFDALN
MUL_1992|M.ulcerans_Agy99 AAMPNICLQMLLRGRNTVGYTPYPEVVTSSFIEEATATGIDIFRIFDALN
MAV_0342|M.avium_104 EAMPNICLQMLLRGRNTVGYTPYPETVTTAFVAEATETGIDIFRIFDALN
MAB_3267c|M.abscessus_ATCC_199 EAVPNICLQMLLRGRNTVGYTPYPETVTKAFIREASATGVDIYRIFDALN
TH_4290|M.thermoresistible__bu KAMPRTRVRAGTRSNGIVTFGLTADSVMDLWVQRLCAHGIGSFWIYDGLF
* *. :: *... * : .: * :: . *:. : *:*.*
Mflv_4198|M.gilvum_PYR-GCK NVDSMRPAIDAVRETGTAVAEVAMSYTGDLSDPAENLYTLDYYLKLAEQI
Mvan_2165|M.vanbaalenii_PYR-1 NVDSMRPAIDAVRETGTAVAEVAMSYTGDLSNPEENLYTLDYYLKLAEQI
MSMEG_6648|M.smegmatis_MC2_155 NVESMRPAIDAVRATGTAVAEVAMSYTSDLSDPAENLYTLDYYLKLAEQI
Mb2991c|M.bovis_AF2122/97 NIESMRPAIDAVRETGSAIAEVAMCYTGDLTDPGEQLYTLDYYLKLAEQI
Rv2967c|M.tuberculosis_H37Rv NIESMRPAIDAVRETGSAIAEVAMCYTGDLTDPGEQLYTLDYYLKLAEQI
MMAR_1749|M.marinum_M NLESMRPAIDAVRETGSAIAEVAMCYTGDLSDPAEQLYTLDYYLRLAEQI
MUL_1992|M.ulcerans_Agy99 NLESMRPAIDAVRETGSAIAEVAMCYTGDLSDPAEQLYTLDYYLRLAEQI
MAV_0342|M.avium_104 NVDSMRPAIDAVRETGSAIAEVAMSYTGDLSDPAEKLYTLDYYLKLADQI
MAB_3267c|M.abscessus_ATCC_199 NIEAMRPAIDAVREVGTSVAEVAMCYTGDLSNPGENLYTLDYYLKLAEQI
TH_4290|M.thermoresistible__bu NIDKIGRLVKVAQAHGAEAVPCILFAD-------SPYHTDEYYAQKTREL
*:: : :...: *: . : . :* :** : : ::
Mflv_4198|M.gilvum_PYR-GCK VDAGAHVLGIKDMAGLLRPQAADTLVRALRSRF-DLPVHVHTHDTPGGQL
Mvan_2165|M.vanbaalenii_PYR-1 VDAGAHVLGIKDMAGLLRPQAAAMLVGALRSRF-DLPVHVHTHDTPGGQL
MSMEG_6648|M.smegmatis_MC2_155 VEAGAHVLAIKDMAGLLRPPAAATLVSALRSRF-DLPVHVHTHDTPGGQL
Mb2991c|M.bovis_AF2122/97 VDAGAHVLAIKDMAGLLRPPAAQRLVSALRSRF-DLPVHLHTHDTPGGQL
Rv2967c|M.tuberculosis_H37Rv VDAGAHVLAIKDMAGLLRPPAAQRLVSALRSRF-DLPVHLHTHDTPGGQL
MMAR_1749|M.marinum_M VEAGAHVLAIKDMAGLLRAPAAHQLVTALRSRF-DLPVHVHTHDTPGGQL
MUL_1992|M.ulcerans_Agy99 VEAGAHVLAIKDMAGLLRAPAAHQLVTALRSRF-DLPVHVHTHDTPGGQL
MAV_0342|M.avium_104 VEAGAHVLAIKDMAGLLRAPAAATLVSALKSRF-DLPVHVHTHDTPGGQL
MAB_3267c|M.abscessus_ATCC_199 VDAGAHVLAIKDMAGLLRPPAAATLVTALRSRF-DLPVHVHTHDTAGGQL
TH_4290|M.thermoresistible__bu VALGADGIELEDAAGLLTPERTRSLIGAIKKEAGDLPVEAHFHSNNALSP
* **. : ::* **** . : *: *::.. ****. * *.. . .
Mflv_4198|M.gilvum_PYR-GCK ATYLAAWQAGASAVDGASSPLAGTTSQPALSSIVAATAHTEFDTGLSLEA
Mvan_2165|M.vanbaalenii_PYR-1 ATYLAAWQAGASAVDGASAPLAGTTSQPALSSIVAATAHTEFDTGLSLSA
MSMEG_6648|M.smegmatis_MC2_155 ATYLAAWQAGASAVDGAAAPLAGTTSQPALSSIVAATAHTEYDTGLPLQA
Mb2991c|M.bovis_AF2122/97 ASYVAAWHAGADAVDGAAAPLAGTTSQPALSSIVAAAAHTEYDTGLSLSA
Rv2967c|M.tuberculosis_H37Rv ASYVAAWHAGADAVDGAAAPLAGTTSQPALSSIVAAAAHTEYDTGLSLSA
MMAR_1749|M.marinum_M ASYVAAWHAGADAVDGAAAPLAGTTSQPALSSIVGAAAHTEYDTGLSLAA
MUL_1992|M.ulcerans_Agy99 ASYVAAWHAGADAVDGAAAPLAGTTSQPALSSIVGAAAHTEYDTGLSLAA
MAV_0342|M.avium_104 ATYVAAWQAGADAVDGAAAPLAGTTSQPALSSIVAAAANTEYDTGLSLPA
MAB_3267c|M.abscessus_ATCC_199 ATYLAAWQAGADAVDGAAAPMAGTTSQPSLSAIVAAAAHSEYDTGVSLTS
TH_4290|M.thermoresistible__bu LNYLEAVLAGADRVHTASRPLAAGVSLPSTENTVANLRYAGFDVEIDDSR
.*: * ***. *. *: *:*. .* *: . *. : :*. :
Mflv_4198|M.gilvum_PYR-GCK VCDLEPYWEALRKVYAPFDVAAAGPTTPTGRVYHHEIPGGQLSNLRQQAI
Mvan_2165|M.vanbaalenii_PYR-1 VCDLEPYWEALRKVYAPFDVAAAGPTTPTGRVYHHEIPGGQLSNLRQQAI
MSMEG_6648|M.smegmatis_MC2_155 VCDLEPYWEALRKVYAPFESGLP---APTGRVYHHEIPGGQLSNLRQQAI
Mb2991c|M.bovis_AF2122/97 VCALEPYWEALRKVYAPFESGLPG---PTGRVYHHEIPGGQLSNLRQQAI
Rv2967c|M.tuberculosis_H37Rv VCALEPYWEALRKVYAPFESGLPG---PTGRVYHHEIPGGQLSNLRQQAI
MMAR_1749|M.marinum_M VCALEPYWEAVRKVYAPFESGLPG---PTGRVYHHEIPGGQLSNLRQQAI
MUL_1992|M.ulcerans_Agy99 VCALEPYWEAVRKVYAPFESGLPG---PTGRVYHHEIPGGQLSNLRQQAI
MAV_0342|M.avium_104 VCDLEPYWEALRKVYAPFESGLPA---PTGRVYHHEIPGGQLSNLRQQAI
MAB_3267c|M.abscessus_ATCC_199 VCDLEPYWEALRKVYAPFESGLPS---PTGRVYTHEIPGGQLSNLRQQAI
TH_4290|M.thermoresistible__bu LEVVEQHLLNVAKIEELPVGRPAEF---SLYQYRHQLPGGMAGTFKNQLK
: :* : : *: . : * *::*** ..:::*
Mflv_4198|M.gilvum_PYR-GCK ALGLGDRFEQIEASYAAADRILGRLVKVTPSSKVVGDLALALVGAGVSAD
Mvan_2165|M.vanbaalenii_PYR-1 ALGLGDRFEEIEASYAAADRILGRLVKVTPSSKVVGDLALALVGAGVSAD
MSMEG_6648|M.smegmatis_MC2_155 ALGLGDRFEEIEASYAAADRVLGRLVKVTPSSKVVGDLALALVGAGVSAE
Mb2991c|M.bovis_AF2122/97 ALGLGDRFEEIEEAYAGADRVLGRLVKVTPTSKVVGDLALALVGAGVSAD
Rv2967c|M.tuberculosis_H37Rv ALGLGDRFEEIEEAYAGADRVLGRLVKVTPTSKVVGDLALALVGAGVSAD
MMAR_1749|M.marinum_M ALGLGDRFEEVEEAYAGADRVLGRLIKVTPSSKVVGDLALALVGAGVSAD
MUL_1992|M.ulcerans_Agy99 ALGLGDRFEEVEEAYAGADRVLGRLIKVTPSSKVVGDLALALVGAGVSAD
MAV_0342|M.avium_104 ALGLGDRFEDIENAYAGADAILGHLVKVTPSSKVVGDLALALVGAGVGAQ
MAB_3267c|M.abscessus_ATCC_199 ALGLGDQFEEIEARYAAADRMLGRLVKVTPSSKVVGDLALALVGTGVSAD
TH_4290|M.thermoresistible__bu DRGMEHRFEEVLDEMALIRRELGYPVMATPFSQLVGTQAVLNV---VTGD
*: .:**:: * ** : .** *::** *: * * .:
Mflv_4198|M.gilvum_PYR-GCK EFAADPERFDIPDSVIGFLRGELGDPPGGWPEPLRSKALAGRAPAKPATE
Mvan_2165|M.vanbaalenii_PYR-1 EFTQDPGRFDIPDSVIGFLRGELGDPPGGWPEPLRSKALAGRAPAKPQAE
MSMEG_6648|M.smegmatis_MC2_155 ELGADPARYNIPDSVIGFLRGELGDPPGGWPEPLRSKALAGRPPAKPQVE
Mb2991c|M.bovis_AF2122/97 EFASDPARFGIPESVLGFLRGELGDPPGGWPEPLRTAALAGRGAARPTAQ
Rv2967c|M.tuberculosis_H37Rv EFASDPARFGIPESVLGFLRGELGDPPGGWPEPLRTAALAGRGAARPTAQ
MMAR_1749|M.marinum_M EFAAEPARFDIPDSVLGFLRGDLGDPVGGWPEPLRSAALAGRAPAKPVGQ
MUL_1992|M.ulcerans_Agy99 EFAAEPARFDIPDAVLGFLRGDLGDPVGGWPEPLRSAALAGRAPAKPVGQ
MAV_0342|M.avium_104 DFAEDPSRYDIPDSVIGFLRGELGDPPGGWPEPLRTKALQGRGPAKPEQP
MAB_3267c|M.abscessus_ATCC_199 EFASDPGRFDIPESVIGFLRGELGDPPGGWPEPFRTRALQGRGPARAEVA
TH_4290|M.thermoresistible__bu RYS------VVPDEVLLYVNGFYGEPVAPLDQDVLDKIMDS-----PKAK
:*: *: ::.* *:* . : . : . .
Mflv_4198|M.gilvum_PYR-GCK LSAEDTAALADAGATRRATLNRLLFPGPTKEFEAHREQYGDTSSLSANQF
Mvan_2165|M.vanbaalenii_PYR-1 LSAEDTEVLADAGPKRQAALNRLLFPAPTKEFEAHREIYGDTSSLSANQF
MSMEG_6648|M.smegmatis_MC2_155 LGAEDEAVLAQAGPKRQAALNRLLFPSPTKEFEQHREAYGDTSQLSANQF
Mb2991c|M.bovis_AF2122/97 LAADDEIALSSVGAKRQATLNRLLFPSPTKEFNEHREAYGDTSQLSANQF
Rv2967c|M.tuberculosis_H37Rv LAADDEIALSSVGAKRQATLNRLLFPSPTKEFNEHREAYGDTSQLSANQF
MMAR_1749|M.marinum_M LTGEDHSALAAPGPKRQATLNRLLFPAPTKEFEEHREAYGDTSQMSANQF
MUL_1992|M.ulcerans_Agy99 LTGEDHSALAAPGPKRQATLNRLLFPAPTKEFEEHREAYGDTSQMSANQF
MAV_0342|M.avium_104 LTAEDEAALAAPGARRQAALNRLLFPGPTKELEEHREQYGDTSGLSANQF
MAB_3267c|M.abscessus_ATCC_199 LTADDESQLDGDSATRRAALNRLLFPGPTKEFLAHREQYGDTSRLSANQF
TH_4290|M.thermoresistible__bu TYAEWEP--------------------PQPELDELRAKFG--KDISDDEL
.: * *: * :* . :* :::
Mflv_4198|M.gilvum_PYR-GCK FYGLRHGDEHRVTLEKGVQLLIGLEAISDADERGMRTVMCILNGQLRPVV
Mvan_2165|M.vanbaalenii_PYR-1 FYGLRHGDEHRVTLERGVELLIGLEAISDPDERGMRTVMCILNGQLRPVV
MSMEG_6648|M.smegmatis_MC2_155 FYGLRSGEEHRVQLERGVELLIGLEAISEPDERGMRTVMCILNGQLRPVL
Mb2991c|M.bovis_AF2122/97 FYGLRQGEEHRVKLERGVELLIGLEAISEPDERGMRTVMCILNGQLRPVL
Rv2967c|M.tuberculosis_H37Rv FYGLRQGEEHRVKLERGVELLIGLEAISEPDERGMRTVMCILNGQLRPVL
MMAR_1749|M.marinum_M FYGLRQGEEHRVKLERGVELLIGLEAISEPDERGMRTVMCIMNGQLRPVL
MUL_1992|M.ulcerans_Agy99 FYGLRQGEEHRVKLERGVELLIGLEAISEPDERGMRTVMCIMNGQLRPVL
MAV_0342|M.avium_104 FYGLRQGDEHRVELERGVELLIGLEAISDPDERGMRTVMCILNGQLRPVV
MAB_3267c|M.abscessus_ATCC_199 FYGLRYGEEHRVKLEKGVELLIGLEAISDADEHGMRTVMCILNGQLRPVQ
TH_4290|M.thermoresistible__bu ILRLLVP-EHDIEVMR---------------------------------A
: * ** : : :
Mflv_4198|M.gilvum_PYR-GCK VRDRSVASEVPAAEKADRNNPDHVAAPFAGVVTVNVAEGDQVETGQTIAT
Mvan_2165|M.vanbaalenii_PYR-1 VRDRSVASDIPAAEKADRTNPDHVAAPFAGVVTVNIAEGDKVDAGQTIAT
MSMEG_6648|M.smegmatis_MC2_155 VRDRSIASDIPAAEKADRSNPDHIAAPFAGVVTVNVEPGDDVTAGQTVAT
Mb2991c|M.bovis_AF2122/97 VRDRSIASAVPAAEKADRGNPGHIAAPFAGVVTVGVCVGERVGAGQTIAT
Rv2967c|M.tuberculosis_H37Rv VRDRSIASAVPAAEKADRGNPGHIAAPFAGVVTVGVCVGERVGAGQTIAT
MMAR_1749|M.marinum_M VRDRSIASAVPTAEKADRGNPGHIAAPFAGVVSVGVAVGDRVSAGQTIAT
MUL_1992|M.ulcerans_Agy99 VRDRSIASAVPTAEKADRGNPGHIAAPFAGVVSVGVAVGDRVSAGQTIAT
MAV_0342|M.avium_104 VRDRSIAIDVPAAEKADRANPDHIAAPFAGVVTVAAEVGRQVEAGQTIAT
MAB_3267c|M.abscessus_ATCC_199 VRDRSIESAVASAEKADRANADHVPAPFAGVVTLNVVSGQEVSAGETIGT
TH_4290|M.thermoresistible__bu TPPRTIDYGLTSRELAN----------IRKLISTSVGAYLHVESGGFELT
. *:: :.: * *: : ::: * :* *
Mflv_4198|M.gilvum_PYR-GCK IEAMKMEAAITAPKAGAVGRVAVSATAQVEGGDLLVVIGSAGAKVSSDGA
Mvan_2165|M.vanbaalenii_PYR-1 IEAMKMEAGITAPKSGTVARVAVSATAQVEGGDLLVVIGSAGR---SEAT
MSMEG_6648|M.smegmatis_MC2_155 IEAMKMEAAITAPKRGVVDRLAVSGTTQVESGDLLLVIR-----------
Mb2991c|M.bovis_AF2122/97 IEAMKMEAPITAPVAGTVERVAVSDTAQVEGGDLLVVVS-----------
Rv2967c|M.tuberculosis_H37Rv IEAMKMEAPITAPVAGTVERVAVSDTAQVEGGDLLVVVS-----------
MMAR_1749|M.marinum_M IEAMKMEAPITAPNDGTVERVAVSSTAQVEGGDLLVVVS-----------
MUL_1992|M.ulcerans_Agy99 IEAMKMEAPITAPNDGTVERVAVSSTAQVEGGDLLVVVS-----------
MAV_0342|M.avium_104 IEAMKMEAAVTSPKSGKVARIAVSRTAQVEGGDLLMVID-----------
MAB_3267c|M.abscessus_ATCC_199 IEAMKMEASITAPKAGTVARVALTETAQVEGGDLLVVIS-----------
TH_4290|M.thermoresistible__bu LHGDH---------------------------------------------
:.. :
Mflv_4198|M.gilvum_PYR-GCK GESS
Mvan_2165|M.vanbaalenii_PYR-1 GESS
MSMEG_6648|M.smegmatis_MC2_155 ----
Mb2991c|M.bovis_AF2122/97 ----
Rv2967c|M.tuberculosis_H37Rv ----
MMAR_1749|M.marinum_M ----
MUL_1992|M.ulcerans_Agy99 ----
MAV_0342|M.avium_104 ----
MAB_3267c|M.abscessus_ATCC_199 ----
TH_4290|M.thermoresistible__bu ----