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M. thermoresistible (build 8) TH_4211 (-)

annotation: DNA polymerase I
coordinates: 1222145 - 1224871
length: 909

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4211--100% (909)DNA polymerase I
M. thermoresistible (build 8)TH_4209-5e-3339.81% (216) PUTATIVE 5'-3' exonuclease

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1655polA0.083.74% (904) DNA polymerase I
M. gilvum PYR-GCKMflv_3564-0.086.67% (908) DNA polymerase I
M. tuberculosis H37RvRv1629polA0.083.74% (904) DNA polymerase I
M. leprae Br4923MLBr_01381polA0.080.71% (897) DNA polymerase I
M. abscessus ATCC 19977MAB_2615c-0.080.56% (900) DNA polymerase I
M. marinum MMMAR_2432polA0.084.73% (897) DNA polymerase I PolA
M. avium 104MAV_3155-0.086.70% (902) DNA polymerase I
M. smegmatis MC2 155MSMEG_3839-0.088.44% (908) DNA polymerase I
M. ulcerans Agy99MUL_1611polA0.084.17% (897) DNA polymerase I
M. vanbaalenii PYR-1Mvan_3361-0.087.57% (909) DNA polymerase I

CLUSTAL 2.0.9 multiple sequence alignment


TH_4211|M.thermoresistible__bu      ----VSPAKTTEQ-PAPAEQTSEQPTLLLLDGNSLAFRAFYALPAENFKT
MSMEG_3839|M.smegmatis_MC2_155      ----MSPAKTATK-KTPAKAADDTPTLMLLDGNSLAFRAFYALPAENFKT
Mflv_3564|M.gilvum_PYR-GCK          ----MSPAKTASK-KAATPAADDTPTLMLLDGNSLAFRAFYALPAENFKT
Mvan_3361|M.vanbaalenii_PYR-1       ----MSPAKTASETKAGKPDTSEKPTLMLLDGNSLAFRAFYALPAENFKT
MAV_3155|M.avium_104                MPATKAATKTATKTAAGAGEEQNRPTLMLLDGNSLAFRAFYALPAENFKT
MMAR_2432|M.marinum_M               --------------MSVATEQSTKPTLMLLDGNSLAFRAFYALPAENFKT
MUL_1611|M.ulcerans_Agy99           --------------MSVATEQSTKPTLMLLDGNSLAFRAFYALPAENFKT
Mb1655|M.bovis_AF2122/97            ----------MVTTASAPSEDRAKPTLMLLDGNSLAFRAFYALPAENFKT
Rv1629|M.tuberculosis_H37Rv         ----------MVTTASAPSEDRAKPTLMLLDGNSLAFRAFYALPAENFKT
MLBr_01381|M.leprae_Br4923          ---------MSAAMTAEVCEDHTKPMLMLLDGNSLAFRAFYALPTENFKT
MAB_2615c|M.abscessus_ATCC_199      ------------MTAPATKTGTKQPTLLLLDGNSLAFRAFYALPAENFKT
                                                   .        * *:****************:*****

TH_4211|M.thermoresistible__bu      KSGLTTNAVYGFTAMLINLLRDENPTHVAAAFDVSRQTFRLDKYPEYKAG
MSMEG_3839|M.smegmatis_MC2_155      QSGLTTNAVYGFTAMLINLLRDEQPTHIAAAFDVSRQTFRKDKYPEYKEG
Mflv_3564|M.gilvum_PYR-GCK          QGGLTTNAVYGFTAMLINLIRDEQPSHIAAAFDVSRQTFRKEKYPEYKEG
Mvan_3361|M.vanbaalenii_PYR-1       KSGLTTNAVYGFTAMLINLLRDEQPTHIAAAFDVSRQTFRKDKYPEYKEG
MAV_3155|M.avium_104                RGGLTTNAVYGFTAMLINLLRDEAPTHIAAAFDVSRQTFRSDRYPEYKAN
MMAR_2432|M.marinum_M               RGGLTTNAVYGFTAMLINLLRDEAPTHIAAAFDVSRQTFRSERYPEYKAN
MUL_1611|M.ulcerans_Agy99           RGGLTTNAVYGFTAMLINLLRDEAPTHIAAAFDVSRQTFRSERYPEYKAN
Mb1655|M.bovis_AF2122/97            RGGLTTNAVYGFTAMLINLLRDEAPTHIAAAFDVSRQTFRLQRYPEYKAN
Rv1629|M.tuberculosis_H37Rv         RGGLTTNAVYGFTAMLINLLRDEAPTHIAAAFDVSRQTFRLQRYPEYKAN
MLBr_01381|M.leprae_Br4923          RGGLTTNAVYGFTAMLINLLREEAPTHIAAAFDVSRKTFRSECYAGYKAN
MAB_2615c|M.abscessus_ATCC_199      QSGLTTNAVYGFTSMLINLLRDEAPTHVAAAFDVSRKTFRSDRYPEYKAT
                                    :.***********:*****:*:* *:*:********:*** : *. **  

TH_4211|M.thermoresistible__bu      RAATPDEFRGQIEITKEVLAALGITVLAEPGYEADDIIATLATQAEAEGF
MSMEG_3839|M.smegmatis_MC2_155      RSATPDEFRGQIDITKEVLGALGITVLAEPGFEADDIIATLATQAEQEGY
Mflv_3564|M.gilvum_PYR-GCK          RSATPDEFRGQIDITKEVLGALGITVLAEAGFEADDIIATLATQAEGEGH
Mvan_3361|M.vanbaalenii_PYR-1       RSATPDEFRGQIDITKEVLGALGITVLAEPGFEADDIIATLATQAENEGH
MAV_3155|M.avium_104                RSATPDEFHGQIDITKEVLAALGITVLAEPGFEADDLIATLATQAENEGY
MMAR_2432|M.marinum_M               RSSTPDEFHGQIDITKEVLNALGITVLAAPGFEADDIIATLATQAEGEGY
MUL_1611|M.ulcerans_Agy99           RSSTPDEFHGQIDITKEVLNALGITVLAAPGFEADDIIATLATQAEGEGY
Mb1655|M.bovis_AF2122/97            RSSTPDEFAGQIDITKEVLGALGITVLSEPGFEADDLIATLATQAENEGY
Rv1629|M.tuberculosis_H37Rv         RSSTPDEFAGQIDITKEVLGALGITVLSEPGFEADDLIATLATQAENEGY
MLBr_01381|M.leprae_Br4923          RSSIPAEFHGQIDITKEVLGALGITVFAEAGFEADDLIATLATQAENEGY
MAB_2615c|M.abscessus_ATCC_199      RSATPDEFRGQIDITKEVLQALGITVLAEEGFEADDIIATLATQGQAEGF
                                    *:: * ** ***:****** ******::  *:****:*******.: **.

TH_4211|M.thermoresistible__bu      RVLIVTGDRDSLQLVTDNVTVLYPRKGVSELTRFTPEAVYEKYGLTPEQY
MSMEG_3839|M.smegmatis_MC2_155      RVLVVTGDRDSLQLVSDQVTVLYPRKGVSELTRFTPDAVVEKYGLTPQQY
Mflv_3564|M.gilvum_PYR-GCK          RVLVVTGDRDALQLVSDDVTVLYPRKGVSELTRFTPEAVQEKYGLTPAQY
Mvan_3361|M.vanbaalenii_PYR-1       RVLVVTGDRDSLQLVSDDVTVLYPRKGVSELTRFTPEAVQEKYGLTPAQY
MAV_3155|M.avium_104                RVLVVTGDRDSLQLVSDNVTVLYPRKGVSELTRFTPEAVVEKYGLTPQQY
MMAR_2432|M.marinum_M               RVLVVTGDRDSLQLVSDDVTVLYPRKGVSELTRFTPEAVVEKYGLTPVQY
MUL_1611|M.ulcerans_Agy99           RVLVVTGDRDSLQLVSDDVTVLYPRKGVSELTRFTPEAVVEKYGLTPVQY
Mb1655|M.bovis_AF2122/97            RVLVVTGDRDALQLVSDDVTVLYPRKGVSELTRFTPEAVVEKYGLTPRQY
Rv1629|M.tuberculosis_H37Rv         RVLVVTGDRDALQLVSDDVTVLYPRKGVSELTRFTPEAVVEKYGLTPRQY
MLBr_01381|M.leprae_Br4923          RVLVVTGDRDALQLVSNDVTVLYPRKGVSELTRFTPEAVIEKYGVTPAQY
MAB_2615c|M.abscessus_ATCC_199      KVFVVTGDRDSLQLVNEDVTVLYPRKGVSDLTRFTPEAVVEKYGLTPSQY
                                    :*::******:****.::***********:******:** ****:** **

TH_4211|M.thermoresistible__bu      PDYAALRGDPSDNLPGIPGVGEKTAAKWIREYGSLQGLVDNVDAVRGKVG
MSMEG_3839|M.smegmatis_MC2_155      PDFAALRGDPSDNLPGIPGVGEKTATKWIVEYGSLQALVDNVDAVKGKVG
Mflv_3564|M.gilvum_PYR-GCK          PDFAALRGDPSDNLPGIPGVGEKTATKWIAEYGSLQGLVDNVDKVKGKVG
Mvan_3361|M.vanbaalenii_PYR-1       PDFAALRGDPSDNLPGIPGVGEKTATKWIAEYGSLQSLVDNVDKVKGKVG
MAV_3155|M.avium_104                PDFAALRGDPSDNLPGIPGVGEKTASKWIAEYGSLQALVDNVDSVRGKVG
MMAR_2432|M.marinum_M               PDFAALRGDPSDNLPGIPGVGEKTASKWIVEYGSLQGLVDQVDSVRGKVG
MUL_1611|M.ulcerans_Agy99           PDFAALRGDPSDNLPGIPGVGEKTASKWIVEYGSLQGLVDQVDSVRGKVG
Mb1655|M.bovis_AF2122/97            PDFAALRGDPSDNLPGIPGVGEKTAAKWIAEYGSLRSLVDNVDAVRGKVG
Rv1629|M.tuberculosis_H37Rv         PDFAALRGDPSDNLPGIPGVGEKTAAKWIAEYGSLRSLVDNVDAVRGKVG
MLBr_01381|M.leprae_Br4923          PDLAALRGDPSDNLPGIPGVGEKTAAKWIVDYGSLQGLVDNVESVRGKVG
MAB_2615c|M.abscessus_ATCC_199      PDFAALRGDPSDNLPGIPGVGEKTASKWILEYGSLQELVDKADTVRGKVG
                                    ** **********************:*** :****: ***:.: *:****

TH_4211|M.thermoresistible__bu      DALRANLSSVVLNRELTDLVRDVPLAHTPETLRMQPWDRDQIHRLFDDLE
MSMEG_3839|M.smegmatis_MC2_155      DALRANLSSVILNRELTDLIRDVPLPQTPDTLRMQPWNRDQIHRLFDDLE
Mflv_3564|M.gilvum_PYR-GCK          DALRAHLSSVVLNRELTELVKDVPLAQTPDTLRMQPWDRDHIHRLFDDLE
Mvan_3361|M.vanbaalenii_PYR-1       DALRAHLSSVVLNRELTDLVKDVPLAHTPDTLRMQPWDRDQIHRLFDDLE
MAV_3155|M.avium_104                DALREHLASVIRNRELTDLIKDVPLAQTPDTLRLQPWDRDQIHRLFDDLE
MMAR_2432|M.marinum_M               DSLRANLASVVRNRELTDLVRDVPLAQTPEALRLQPWDRDQIHRLFDDLE
MUL_1611|M.ulcerans_Agy99           DSLRANLASVVRNRELTDLVRDVPLAQTPEVLLLQPWDRDQIHRLFDDLE
Mb1655|M.bovis_AF2122/97            DALRANLASVVRNRELTDLVRDVPLAQTPDTLRLQPWDRDHIHRLFDDLE
Rv1629|M.tuberculosis_H37Rv         DALRANLASVVRNRELTDLVRDVPLAQTPDTLRLQPWDRDHIHRLFDDLE
MLBr_01381|M.leprae_Br4923          EALRTHLASVVRNRELTELVKDVPLVQTSDTLRLQPWDRDRIHRLFDNLE
MAB_2615c|M.abscessus_ATCC_199      DSLRANLASVILNRELTDLVRTVPLPYVPAQLALAPWDRDQIHRLFDDLE
                                    ::** :*:**: *****:*:: ***  ..  * : **:**:******:**

TH_4211|M.thermoresistible__bu      FRVLRDRLFETLSSADP---EVEHGFDVRGRALEPGELAAWLAEHS-LGN
MSMEG_3839|M.smegmatis_MC2_155      FRVLRDRLFETLVAVEP---EVEHGFDVRGRALEPGELAAWLSEHS-LGS
Mflv_3564|M.gilvum_PYR-GCK          FRVLRDRLFDTLASADP---EVEEGFDVQGEALQAGTLAPWLAENS-DGR
Mvan_3361|M.vanbaalenii_PYR-1       FRVLRDRLFDTLASADP---EVEEGFEVRGEALEAGTLAAWLAEHS-NGQ
MAV_3155|M.avium_104                FRVLRDRLFETLAAVEP---EVDEGFDVRGGALEAGELAVWLAEHS-SGK
MMAR_2432|M.marinum_M               FRVLRDRLFDTLAAVEP---EVDQGFDVRGGAVSPGAVAQWLAEHVVDGR
MUL_1611|M.ulcerans_Agy99           FRVLRDRLFDTLAAVEP---EVDQGFDVRGGAVSPGAVAQWLAEHVVDGR
Mb1655|M.bovis_AF2122/97            FRVLRDRLFDTLAAAGG--PEVDEGFDVRGGALAPGTVRQWLAEHAGDGR
Rv1629|M.tuberculosis_H37Rv         FRVLRDRLFDTLAAAGG--PEVDEGFDVRGGALAPGTVRQWLAEHAGDGR
MLBr_01381|M.leprae_Br4923          FRVLRDRLFEALAAAGERVPEVDEGFDVRGGLLESGTVGRWLAKHADDGR
MAB_2615c|M.abscessus_ATCC_199      FRVLRDRLFETLEAVEP---EVDEGFQLAGQALEPGTVAAWLAEHTGDGR
                                    *********::* :.     **:.**:: *  : .* :  **:::   * 

TH_4211|M.thermoresistible__bu      RFGLAVVGTHRTFDSDATALAIVAADGEGRYIDTATLHPDDEAALASWLA
MSMEG_3839|M.smegmatis_MC2_155      RFGVAVVGTHKAYDADATALAIVAADGDGRYIDTSTLTPEDEAALASWLA
Mflv_3564|M.gilvum_PYR-GCK          RFGLAVVGNHLAFDSDATALTIVASGGEGRYIDTTGLDPDDEKALASWLA
Mvan_3361|M.vanbaalenii_PYR-1       RFGVAVVGNHLAFDSDATAVALVASDGDGRYIDTTRLDPEDEKALASWLA
MAV_3155|M.avium_104                RFGLAVAGTHLAYDADCTALAIVSADGEGRYIDTSALDPDDEAALASWLA
MMAR_2432|M.marinum_M               RCGLTVVGTHLPHGGDATALAIAAADGEGGYIDTATLTPDDDAALGEWLA
MUL_1611|M.ulcerans_Agy99           RCGLTVVGTHLPHGGDATALAIAAADGEGGYIDTATLTPDDDAALGEWLA
Mb1655|M.bovis_AF2122/97            RAGLTVVGTHLPHGGDATAMAVAAADGEGAYLDTATLTPDDDAALAAWLA
Rv1629|M.tuberculosis_H37Rv         RAGLTVVGTHLPHGGDATAMAVAAADGEGAYLDTATLTPDDDAALAAWLA
MLBr_01381|M.leprae_Br4923          RSGLAIVGTHLPHGGDATALAVAAADGNGGYIDTAMLTPDDDDALAAWLA
MAB_2615c|M.abscessus_ATCC_199      RSGLAVVGTYTPYDGDATAVAIASADGDGAYIDTTTVTPDDEAALAEWLA
                                    * *:::.*.: ....*.**:::.::.*:* *:**: : *:*: **. ***

TH_4211|M.thermoresistible__bu      DPGPPKALHEAKQAMHDLAGRGWRLNGVTSDTALAAYLVRPGQRSFALDD
MSMEG_3839|M.smegmatis_MC2_155      DPGPPKALHEAKLAMHDLAGRGWTLRGVTSDTALAAYLVRPGQRSFTLDD
Mflv_3564|M.gilvum_PYR-GCK          DPHVPKALHEAKLAIHDLQGRGWTLAGVTSDTALAAYLVRPGQRSFALDD
Mvan_3361|M.vanbaalenii_PYR-1       DPDAPKALHEAKLAMHDLQGRGWTLAGVTSDTALAAYLVRPGQRSFALDD
MAV_3155|M.avium_104                DPGPPKALHEAKLAMHDLAGRGWTLAGVTSDTALAAYLVRPGQRSFSLDD
MMAR_2432|M.marinum_M               DPAKPKALHEAKLAIHDLRGRGWTLNGVTSDTALAAYLVRPGQRSFTLDD
MUL_1611|M.ulcerans_Agy99           DPAKPKALHEAKLAIHDLRGRGWTLNGVTSDTALAAYLVRPGQRSFTLDD
Mb1655|M.bovis_AF2122/97            DPAKPKALHEAKAAVHDLAGRGWTLEGVTSDTALAAYLVRPGQRSFTLDD
Rv1629|M.tuberculosis_H37Rv         DPAKPKALHEAKAAVHDLAGRGWTLEGVTSDTALAAYLVRPGQRSFTLDD
MLBr_01381|M.leprae_Br4923          DPDNPKALHEAKLAMHDLAGRGWTLGGITSDTALAAYLVRPGQRSFTLDD
MAB_2615c|M.abscessus_ATCC_199      DAARPKALHEAKQAIHALAGRGWELGGVTSDTALAAYLVRPGQRSFALDD
                                    *.  ******** *:* * **** * *:******************:***

TH_4211|M.thermoresistible__bu      LTLRYLRRELRAEEPEQQQLSLLDESDGVDEQAVQTLLLRACAVMDLADA
MSMEG_3839|M.smegmatis_MC2_155      LAVRYLHRELRAETPEQQQLSLLDDSDGVDEQAVQTVILRACAVLDLADA
Mflv_3564|M.gilvum_PYR-GCK          LSLRYLKRELRADNPEQQQLSLLDDSDGVDDQAVQTLLLRASAVVDLADA
Mvan_3361|M.vanbaalenii_PYR-1       LSLRYLKRELRADNPEQQQLSLLDDSDAVDDQAVQTLLLRAGAVVDLADA
MAV_3155|M.avium_104                LALRYLRRELRAENPQQQQLSLLDDTDGTDDQAVQTLILRAVAVLDLADA
MMAR_2432|M.marinum_M               LSLRYLRRELRAETPEQQQLSLLD-DDDTDVAAAQTAILRARAVIDLADA
MUL_1611|M.ulcerans_Agy99           LSLRYLRRELRAETPEQQQLSLLD-DDDTDVAAAQTAILRARAVIDLADA
Mb1655|M.bovis_AF2122/97            LSLRYLRRELRAETPQQQQLSLLD-DDDTDAETIQTTILRARAVIDLADA
Rv1629|M.tuberculosis_H37Rv         LSLRYLRRELRAETPQQQQLSLLD-DDDTDAETIQTTILRARAVIDLADA
MLBr_01381|M.leprae_Br4923          LSLRYLRRELRAETPEQEQFSLLDNVDEVDKQAIQTLILRARAVVDLAAA
MAB_2615c|M.abscessus_ATCC_199      LSLRYLRRELRAEDDGEQQLSLLDEDGAGDAKAAQAQMLRARAVIDLADA
                                    *::***:*****:   ::*:****  .  *  : *: :*** **:*** *

TH_4211|M.thermoresistible__bu      LDEELARIDSLSLLERMELPVQRVLFEMETAGIAVDLDRLGELQSEFAGQ
MSMEG_3839|M.smegmatis_MC2_155      LDQELARIDSLSLLSRMELPVQRTLAEMEHAGIAVDLGMLEQLQSEFADQ
Mflv_3564|M.gilvum_PYR-GCK          LDEELARIDSSALLGNMELPVQRVLAELETAGIAVDLEMLSGLQSEFADQ
Mvan_3361|M.vanbaalenii_PYR-1       LDEELARIDSSALLGSMELPVQRVLAQLETVGIAVDLAMLSELQSEFAGQ
MAV_3155|M.avium_104                LDEELARINSTSLLSGMELPVQRVLAGMEKAGIAVDLDLLSELQSDFAHQ
MMAR_2432|M.marinum_M               LDAELDRIDSTGLLADMELPVQHVLAEMETAGIAVDLTMLGGLQSHFADQ
MUL_1611|M.ulcerans_Agy99           LDAELDRIDSTGLLTDMELPVQHLLAEMETAGIAVDLTMLGGLQRHFADQ
Mb1655|M.bovis_AF2122/97            LDAELARIDSTALLGEMELPVQRVLAKMESAGIAVDLPMLTELQSQFGDQ
Rv1629|M.tuberculosis_H37Rv         LDAELARIDSTALLGEMELPVQRVLAKMESAGIAVDLPMLTELQSQFGDQ
MLBr_01381|M.leprae_Br4923          LDAELDLIDSTSLLGEMELPVQQVLADMEKAGIAADLRLLTELQSQFGDQ
MAB_2615c|M.abscessus_ATCC_199      LDVELERIESAGLLTDMELPVQRVLAGLESVGIAVDTDHLSSLQNQFASG
                                    ** **  *:* .**  ******: *  :* .***.*   *  ** .*.  

TH_4211|M.thermoresistible__bu      IRDAAEAAYAVIGKQINLGSPKQLQGVLFDELGMPKTKRTKTGYTTDADA
MSMEG_3839|M.smegmatis_MC2_155      IRDAAEAAYSVIGKQINLGSPKQLQAVLFDELEMPKTKKTKTGYTTDADA
Mflv_3564|M.gilvum_PYR-GCK          IRDAAEAAYAVIGKQINLGSPKQLQVVLFDELEMPKTKRTKTGYTTDADA
Mvan_3361|M.vanbaalenii_PYR-1       IRDAAEAAYAVIGKQINLGSPKQLQVVLFDELEMPKTKRTKTGYTTDADA
MAV_3155|M.avium_104                IRDAAEAAYAVIGKQINLGSPKQLQAVLFDELQMPKTKRTKTGYTTDADA
MMAR_2432|M.marinum_M               IRDAAEAAYAVIGKQINLGSPKQLQVVLFDELGMPKTKRTKTGYTTDADA
MUL_1611|M.ulcerans_Agy99           IRDAAEAAYAVIGKQINLGSPKQLQVVLFDELRMPKTKRTKTGYTTDADA
Mb1655|M.bovis_AF2122/97            IRDAAEAAYGVIGKQINLGSPKQLQVVLFDELGMPKTKRTKTGYTTDADA
Rv1629|M.tuberculosis_H37Rv         IRDAAEAAYGVIGKQINLGSPKQLQVVLFDELGMPKTKRTKTGYTTDADA
MLBr_01381|M.leprae_Br4923          IRDAAEAAYAVIGKQINLSSPKQLQVVLFEELGMPKTKRTKTGYTTDADA
MAB_2615c|M.abscessus_ATCC_199      IREAADAAYAVIGKQINLGSPKQLQVVLFDELGMPKTKKTKTGYTTDADA
                                    **:**:***.********.****** ***:** *****:***********

TH_4211|M.thermoresistible__bu      LQSLFEKTGHPFLQHLLAHRDATRLKVTVDGLLNSVAADGRIHTTFNQTI
MSMEG_3839|M.smegmatis_MC2_155      LQSLFEKTGHPFLQHLLAHRDATRLKVTVDGLLNSVASDGRIHTTFNQTI
Mflv_3564|M.gilvum_PYR-GCK          LQSLFDKTGHPFLQHLLAHRDATRLKVTVDGLLNAVASDGRIHTTFNQTI
Mvan_3361|M.vanbaalenii_PYR-1       LQSLFDKTGHPFLQHLLAHRDATRLKVTVDGLLNSVAADGRIHTTFNQTI
MAV_3155|M.avium_104                LQSLFDKTGHPFLQHLLAHRDATRLKVTVDGLLNSVASDGRIHTTFNQTI
MMAR_2432|M.marinum_M               LQSLFDKTGHPFLQHLLAHRDVTRLKVTVDGLLNSVADDGRIHTTFNQTI
MUL_1611|M.ulcerans_Agy99           LQSLFDKTGHPFLQHLLAHRDVTRLKVTVDGLLNSVADDGRIHTTFNQTI
Mb1655|M.bovis_AF2122/97            LQSLFDKTGHPFLQHLLAHRDVTRLKVTVDGLLQAVAADGRIHTTFNQTI
Rv1629|M.tuberculosis_H37Rv         LQSLFDKTGHPFLQHLLAHRDVTRLKVTVDGLLQAVAADGRIHTTFNQTI
MLBr_01381|M.leprae_Br4923          LQSLFCKTEHPFLQHLLTHRDVTRLKVTVDGLLNAVAADGRIHTTFNQTI
MAB_2615c|M.abscessus_ATCC_199      LQTLFDKTGHPFLEHLLTHRDVTRLKVTVDGLLKSVAADGRIHTTFNQTI
                                    **:** ** ****:***:***.***********::** ************

TH_4211|M.thermoresistible__bu      AATGRLSSTEPNLQNIPIRTEAGRMIRDAFVVG---DGYAELMTADYSQI
MSMEG_3839|M.smegmatis_MC2_155      AATGRLSSTEPNLQNIPIRTEAGRRIRDAFVVG---EGYAELMTADYSQI
Mflv_3564|M.gilvum_PYR-GCK          AATGRLSSTEPNLQNIPIRTEAGRRIRDAFVVG---DGYGELMTADYSQI
Mvan_3361|M.vanbaalenii_PYR-1       AATGRLSSTEPNLQNIPIRTEAGRRIRDGFVVG---EGYADLMTADYSQI
MAV_3155|M.avium_104                AATGRLSSTEPNLQNIPIRTEAGRRIRDAFVVG---DGYAELMTADYSQI
MMAR_2432|M.marinum_M               AATGRLSSTEPNLQNIPIRTDAGRQIRDAFVVG---DGYSELMTADYSQI
MUL_1611|M.ulcerans_Agy99           AATGRLSSTEPNLQNIPIRTDAGRQIRDAFVVG---DGYSELMTADYSQI
Mb1655|M.bovis_AF2122/97            AATGRLSSTEPNLQNIPIRTDAGRRIRDAFVVG---DGYAELMTADYSQI
Rv1629|M.tuberculosis_H37Rv         AATGRLSSTEPNLQNIPIRTDAGRRIRDAFVVG---DGYAELMTADYSQI
MLBr_01381|M.leprae_Br4923          ATTGRLSSTEPNLQNIPIRTNAGRQIRDAFVVGSENNGYTELMTADYSQI
MAB_2615c|M.abscessus_ATCC_199      AATGRLSSTEPNLQNIPVRTEAGREIRDGFVVG---AGYRELMTVDYSQI
                                    *:***************:**:*** ***.****    ** :***.*****

TH_4211|M.thermoresistible__bu      EMRIMAHLSGDEGLIEAFRTGEDLHSFVASRAFSVPIEEVTPELRRRVKA
MSMEG_3839|M.smegmatis_MC2_155      EMRIMAHLSRDAGLIEAFNTGEDLHSFVASRAFSVPIDEVTPELRRRVKA
Mflv_3564|M.gilvum_PYR-GCK          EMRIMAHLSRDEGLIEAFNTGEDLHSFVASRAFSVPIDEVTAELRRRVKA
Mvan_3361|M.vanbaalenii_PYR-1       EMRIMAHLSKDAGLIEAFNTGEDLHSFVASRAFSVPLDEVTPELRRRVKA
MAV_3155|M.avium_104                EMRIMAHLSQDAGLIEAFNTGEDLHSFVASRAFGVPIEEVTGELRRRVKA
MMAR_2432|M.marinum_M               EMRIMAHLSRDEGLIEAFNTGEDLHSFVASRAFGVPIDEVTGELRRRVKA
MUL_1611|M.ulcerans_Agy99           EMRIMAHLSRDEGLIEAFNTGEDLHSFVASRAFGVPIDEVTGELRRRVKA
Mb1655|M.bovis_AF2122/97            EMRIMAHLSGDEGLIEAFNTGEDLHSFVASRAFGVPIDEVTGELRRRVKA
Rv1629|M.tuberculosis_H37Rv         EMRIMAHLSGDEGLIEAFNTGEDLHSFVASRAFGVPIDEVTGELRRRVKA
MLBr_01381|M.leprae_Br4923          EMRIMAHLSRDEGLIEAFHTGEDLHSFVASRAFGIPIEDITPELRRRVKA
MAB_2615c|M.abscessus_ATCC_199      EMRIMAHLSADEGLIEAFNTGEDLHSFVAARAFGVPIDEVTAELRRRVKA
                                    ********* * ******.**********:***.:*::::* ********

TH_4211|M.thermoresistible__bu      MSYGLAYGLSAYGLAQQLKISTEEAKVQMEQYFARFGKVRDYLQSVVEQA
MSMEG_3839|M.smegmatis_MC2_155      MSYGLAYGLSAYGLAQQLKISTEEAKVQMEQYFDRFGGVRDYLRDVVDQA
Mflv_3564|M.gilvum_PYR-GCK          MSYGLAYGLSAYGLSQQLKISTEEAKEQMEQYFARFGGVRDYLRDVVDQA
Mvan_3361|M.vanbaalenii_PYR-1       MSYGLAYGLSAYGLSQQLKISTEEAKEQMEQYFARFGGVRDYLRDVVDQA
MAV_3155|M.avium_104                MSYGLAYGLSAYGLSQQLKISTEEAKEQMDAYFARFGGVRDYLHAVVEQA
MMAR_2432|M.marinum_M               MSYGLAYGLSAYGLSSQLKISTEDAKVQMDQYFSRFGGVRDYLMAVVEQA
MUL_1611|M.ulcerans_Agy99           MSYGLAYGLSAYGLSSQLKISTEDAKVQMDQYFSRFGGVRDYLMAVVEQA
Mb1655|M.bovis_AF2122/97            MSYGLAYGLSAYGLSQQLKISTEEANEQMDAYFARFGGVRDYLRAVVERA
Rv1629|M.tuberculosis_H37Rv         MSYGLAYGLSAYGLSQQLKISTEEANEQMDAYFARFGGVRDYLRAVVERA
MLBr_01381|M.leprae_Br4923          MSYGLAYGLSAYGLATQLKISTEEAKLQMEQYFARFGGVRDYLMDVVEQA
MAB_2615c|M.abscessus_ATCC_199      MSYGLAYGLSAYGLATQLKISNDEAKEQMDQYFSRFGGVRDYLRAVVDQA
                                    **************: *****.::*: **: ** *** *****  **::*

TH_4211|M.thermoresistible__bu      RKDGYTSTVLGRRRYLPELDSSNRQVREAAERAALNAPIQGSAADIIKVA
MSMEG_3839|M.smegmatis_MC2_155      RKDGYTSTVLGRRRYLPELDSSNRQVREAAERAALNAPIQGSAADIIKVA
Mflv_3564|M.gilvum_PYR-GCK          RKDGYTSTVFGRRRYLPELDSSNRQVREAAERAALNAPIQGSAADIIKVA
Mvan_3361|M.vanbaalenii_PYR-1       RKDGYTSTVFGRRRYLPELDSSNRQVREAAERAALNAPIQGSAADIIKVA
MAV_3155|M.avium_104                RKDGYTSTVLGRRRYLPELDSSNRQVREAAERAALNAPIQGSAADIIKVA
MMAR_2432|M.marinum_M               RKDGYTSTVLGRRRYLPELDSSNRQVREAAERAALNAPIQGSAADIIKVA
MUL_1611|M.ulcerans_Agy99           RKDGYTSTVLGRRRHLPELDSSNRQVREAAERAALNAPIQGSAADIIKVA
Mb1655|M.bovis_AF2122/97            RKDGYTSTVLGRRRYLPELDSSNRQVREAAERAALNAPIQGSAADIIKVA
Rv1629|M.tuberculosis_H37Rv         RKDGYTSTVLGRRRYLPELDSSNRQVREAAERAALNAPIQGSAADIIKVA
MLBr_01381|M.leprae_Br4923          RKDGYTSTVLGRRRYLPELDSSNRQIREAAERAALNAPIQGSAADIIKVA
MAB_2615c|M.abscessus_ATCC_199      RKDGYTSTVLGRRRYLPDLDSGDRLRREAAERAALNAPIQGSAADIIKVA
                                    *********:****:**:***.:*  ************************

TH_4211|M.thermoresistible__bu      MINVDEAIKAAGLKSRMLLQVHDELLFEVAPGERDTLEQLVREQMGGAYP
MSMEG_3839|M.smegmatis_MC2_155      MINVDQAIKDAGLRSRILLQVHDELLFEVSEGEQGELEQLVREHMGNAYP
Mflv_3564|M.gilvum_PYR-GCK          MINVDQAIKDAGLKSRTLLQVHDELLFEVADGERDTLDALVREHMGSAYA
Mvan_3361|M.vanbaalenii_PYR-1       MINVDQAIKEAGLSSRMLLQVHDELLFEVADGERDALDALVREHMGSAYR
MAV_3155|M.avium_104                MIEVDKAIKEAGLQSRILLQVHDELLFEVAAGEREQLEALARDKMGGAYP
MMAR_2432|M.marinum_M               MIEVDKALKEHALKSRMLLQVHDELLFEVAAGEREQIEALVRDKMGSAYP
MUL_1611|M.ulcerans_Agy99           MIEVDKALKEHALKSRMLLQVHDELLFEVAAGEREQIEALVRDKMGSAYP
Mb1655|M.bovis_AF2122/97            MIQVDKALNEAQLASRMLLQVHDELLFEIAPGERERVEALVRDKMGGAYP
Rv1629|M.tuberculosis_H37Rv         MIQVDKALNEAQLASRMLLQVHDELLFEIAPGERERVEALVRDKMGGAYP
MLBr_01381|M.leprae_Br4923          MIAVDKSLKQAKLASRMLLQVHDELLFEVAIGEREQIEAMVREQMGSAYP
MAB_2615c|M.abscessus_ATCC_199      MITTDKALRDKGLRSRMLLQVHDELLFEVAEGERESLEALVRKTMGSAYP
                                    ** .*:::.   * ** ***********:: **:  :: :.*. **.** 

TH_4211|M.thermoresistible__bu      LDVPLEVSVGFGRSWDAAAH
MSMEG_3839|M.smegmatis_MC2_155      LDVPLEVSVGYGRSWDAAAH
Mflv_3564|M.gilvum_PYR-GCK          LDVPLEVSVGFGRSWDAAAH
Mvan_3361|M.vanbaalenii_PYR-1       LDVPLEVSVGYGRSWDSAAH
MAV_3155|M.avium_104                LDVPLEVSVGYGRSWDAAAH
MMAR_2432|M.marinum_M               LDVPLEVSVGFGRSWDSAAH
MUL_1611|M.ulcerans_Agy99           LDVPLEVSVGFGRSWDSAAH
Mb1655|M.bovis_AF2122/97            LDVPLEVSVGYGRSWDAAAH
Rv1629|M.tuberculosis_H37Rv         LDVPLEVSVGYGRSWDAAAH
MLBr_01381|M.leprae_Br4923          LDVPLEVSVGFGRSWGAAAH
MAB_2615c|M.abscessus_ATCC_199      LDVPLEVSVGYGRSWDAAAH
                                    **********:****.:***