For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4068 | - | - | 100% (821) | putative conserved hypothetical protein |
| M. thermoresistible (build 8) | TH_2700 | - | 2e-70 | 35.91% (596) | PUTATIVE putative AAA ATPase containing von Willebrand factor |
| M. thermoresistible (build 8) | TH_3772 | - | 7e-61 | 32.70% (581) | PUTATIVE putative AAA ATPase containing von Willebrand factor |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2640 | PPE42 | 3e-09 | 33.33% (132) | PPE family protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2608 | PPE42 | 3e-09 | 33.33% (132) | PPE family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0974 | - | 9e-07 | 29.41% (153) | hypothetical protein MAB_0974 |
| M. marinum M | MMAR_0371 | - | 8e-08 | 24.86% (362) | PE family protein |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0200 | - | 3e-70 | 30.22% (857) | hypothetical protein MSMEG_0200 |
| M. ulcerans Agy99 | MUL_2440 | - | 1e-05 | 33.85% (130) | PPE family protein |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2640|M.bovis_AF2122/97 MNFAVLPPEVNSARIFAGAGLGPMLAAASAWDGLAEELHAAAGSFASVTT
Rv2608|M.tuberculosis_H37Rv MNFAVLPPEVNSARIFAGAGLGPMLAAASAWDGLAEELHAAAGSFASVTT
MMAR_0371|M.marinum_M ----------------------------------MTYVFVEPETITTMAA
MUL_2440|M.ulcerans_Agy99 -----------------------MLAAAAAWDGTGQELAAAASAFSSLTS
TH_4068|M.thermoresistible__bu -----VGSQRRTRAGHYFTKATLAGGVAASVTALTLGLAAPSATAAATPA
MSMEG_0200|M.smegmatis_MC2_155 ------MAGKNRKRGQRAKKIATLSAATVTATALTAGIAPIGEANAAVVA
MAB_0974|M.abscessus_ATCC_1997 ------------------MHVGIRTVAVAAVCGLCVGAGVDARAVRPNLS
: . :
Mb2640|M.bovis_AF2122/97 GLAGDAWHG------PASLAMTRAASPYVGWLNTAAGQAAQAAGQARLAA
Rv2608|M.tuberculosis_H37Rv GLAGDAWHG------PASLAMTRAASPYVGWLNTAAGQAAQAAGQARLAA
MMAR_0371|M.marinum_M DLEGIGSTI------DAASAAAAGPTS---RLVSAAADEVSTA-----IA
MUL_2440|M.ulcerans_Agy99 DLAGAAWQG------PSAAAMASVATSYVRWLGSAASGAVQTARQVATSA
TH_4068|M.thermoresistible__bu GADAVQYVD------KSGRIIPTAVAEALAEVLRAYAEGAPPTRFPAELR
MSMEG_0200|M.smegmatis_MC2_155 REAALQADVRPFPPPDQIPDITGGLGAAGYDLAQAIGAQVMTSLMESISL
MAB_0974|M.abscessus_ATCC_1997 IAGTPTTRS--------VSSQAVSLASFSDLLAAAAPQNDAAAQMNSVGG
. : * .:
Mb2640|M.bovis_AF2122/97 SAFEATLAATVSPAMVAANRTRLASLVAANLLGQNAPAIAAAEAEYEQIW
Rv2608|M.tuberculosis_H37Rv SAFEATLAATVSPAMVAANRTRLASLVAANLLGQNAPAIAAAEAEYEQIW
MMAR_0371|M.marinum_M GLFGG--------------------------YGQQYQAVVAHAAAFHQQF
MUL_2440|M.ulcerans_Agy99 AVFEAARTATVPLELVAANRSALMSMVAANVFGLNAPAIAAIEAQYEQMW
TH_4068|M.thermoresistible__bu ALFEDLDQLG-PELLSALGSEENVGYLRSLDFGFLFEDLGLDLPDLGDLL
MSMEG_0200|M.smegmatis_MC2_155 AALAQAAGIDPQSIATGLLNEAIGSVLGGTLDQLPIDLTGVLQPLLAQVL
MAB_0974|M.abscessus_ATCC_1997 GAVSSTDLIGTVAKLLATPNITQSGVTP----GINTAAVGTVDPPSSEPV
. . . :
Mb2640|M.bovis_AF2122/97 AQDVAAMFGYH-------SAASAVATQLAPIQEGLQQQLQNVLAQLASGN
Rv2608|M.tuberculosis_H37Rv AQDVAAMFGYH-------SAASAVATQLAPIQEGLQQQLQNVLAQLASGN
MMAR_0371|M.marinum_M TQTV-AAAGLA-------YAQTEASS-VAAISNALEAFGTQAHSLLGGG-
MUL_2440|M.ulcerans_Agy99 AQNVGAMFGYH-------VGVSEALSGLAPWQEVLSGVSGRVASALEGT-
TH_4068|M.thermoresistible__bu TAIPASFPIGE-------EEEIALPLNIITTGAPFGALSLLGLNPLWAPG
MSMEG_0200|M.smegmatis_MC2_155 TPLVSEILGELPIGGALGDALIGVVAGLVVSTLALELSDLGAIDNVGALL
MAB_0974|M.abscessus_ATCC_1997 DPPTGQPTDPP------AADEPAPPTNFPGERPAFGTPSYFAQLAFAVFH
. : .
Mb2640|M.bovis_AF2122/97 LGSGNVGVGNIGNDNIGNANIGFGNRGDANIGIGNIGDRNLGIGNTGNWN
Rv2608|M.tuberculosis_H37Rv LGSGNVGVGNIGNDNIGNANIGFGNRGDANIGIGNIGDRNLGIGNTGNWN
MMAR_0371|M.marinum_M --------------------------------------------------
MUL_2440|M.ulcerans_Agy99 --------------------------------------------------
TH_4068|M.thermoresistible__bu --------------------------------------------------
MSMEG_0200|M.smegmatis_MC2_155 AALGLDLSNPLNLSGDPIPGLNLVTTGSPFTFLKLFG---------VDLG
MAB_0974|M.abscessus_ATCC_1997 VVALP---------------------------------------------
Mb2640|M.bovis_AF2122/97 IGIGITGNGQIGFGKPANPDVLVVGNGGPGVTALVMGGTDSLLSLPNIPL
Rv2608|M.tuberculosis_H37Rv IGIGITGNGQIGFGKPANPDVLVVGNGGPGVTALVMGGTDSLLPLPNIPL
MMAR_0371|M.marinum_M -----NAAASATP-----SASITTTPLTGPTVSLVMGGSGNPLPGPDY-L
MUL_2440|M.ulcerans_Agy99 -----SAAAAAALGPTALTAAGSALPAAATDVTLVIGGSGFPIPSQSY-V
TH_4068|M.thermoresistible__bu ----LPDAIARDINGTPYADIDTTLRVPPTTIVFTEEQYQQFRQQAYDLA
MSMEG_0200|M.smegmatis_MC2_155 WVPPFPNPVAEDINNTEYLKVGLAGLLENLGIELDPIDLDILDLNLLGVD
MAB_0974|M.abscessus_ATCC_1997 ----ITVPVQFFLGSAEGVPTVIAAAINDLSGLLGQIPGLSPQQPTEPQP
. :
Mb2640|M.bovis_AF2122/97 LEYAARFITPVHPG---YTATFLET---------PSQFFPFTGLNSLTYD
Rv2608|M.tuberculosis_H37Rv LEYAARFITPVHPG---YTATFLET---------PSQFFPFTGLNSLTYD
MMAR_0371|M.marinum_M ADFFN-YITPQFG---VTTSQALFT---------PEQLYPLTGEKSLPLA
MUL_2440|M.ulcerans_Agy99 DNVVNNFVTPNFPSFTVSNAISLFT---------PAESYWITGIKTMTED
TH_4068|M.thermoresistible__bu YNETYDALCPSGCSGFGETGARLAA---------QAAGSAARALVPREIT
MSMEG_0200|M.smegmatis_MC2_155 LSVLESVLDGLGLGLDLGNSGGLLGGLLGGLGLDLGLDLDALGLGTLDPN
MAB_0974|M.abscessus_ATCC_1997 QQIAQSSLPLQKLAAAETDPTTDPE---------PPAEPLPTNFPGPRPA
. :
Mb2640|M.bovis_AF2122/97 VSVAQGVTNLHTAIMAQLAAGNEVVVFGTSQSATIATFEMR---YLQSLP
Rv2608|M.tuberculosis_H37Rv VSVAQGVTNLHTAIMAQLAAGNEVVVFGTSQSATIATFEMR---YLQSLP
MMAR_0371|M.marinum_M ISVSQGVQILHNAILGQIAEGNSVVVGGYSQSAIIASLEMQ---NLAAMP
MUL_2440|M.ulcerans_Agy99 ASWAEGLTILDTAIKAQLAAGNNVVVQGYSQGAGIASLEMS---NLKAAG
TH_4068|M.thermoresistible__bu AGAEAPLALRNYRIPIVLGFGLGSLAAGMAYPQVVADLANQP--GGTGET
MSMEG_0200|M.smegmatis_MC2_155 EILNLLPDVVALRIPIVVGFQLGAFAAGAAYQQVVDELPNQPGGANYQGT
MAB_0974|M.abscessus_ATCC_1997 FGTPSYFAQLAFAVLHVLALPITVPVQAIIGKTEGVPSVIVAALNDLSSL
: :. . .
Mb2640|M.bovis_AF2122/97 AHLRPGLDELSFTLTGNPNRPDGGILTRFG-------FSIPQLGFTLSGA
Rv2608|M.tuberculosis_H37Rv AHLRPGLDELSFTLTGNPNRPDGGILTRFG-------FSIPQLGFTLSGA
MMAR_0371|M.marinum_M PGTAPTADQLGFLLLANPMNPNGGLLSRFAG------LTLPSLGVDFYGS
MUL_2440|M.ulcerans_Agy99 ---VPTG-SVSFSLIGNAMNPNGGLYERFAG------LVSPSLGKTFWGA
TH_4068|M.thermoresistible__bu AADGSSLTILPLILLRNPGRANGGIAARFGSFADLIGLNTVTPDMDVERD
MSMEG_0200|M.smegmatis_MC2_155 NPLLGSFTILPMVLIDNPGRANGGLFARAYPLFRLMGIDTVTPDTQVQSS
MAB_0974|M.abscessus_ATCC_1997 LGQVPKPSAPVTDTKTTPQDSTSQQADKAAP-------TVDSASEKPGGA
.. . . : .
Mb2640|M.bovis_AF2122/97 TP------------------ADAYPTVDYAFQYDGVNDFPKYPLNVFATA
Rv2608|M.tuberculosis_H37Rv TP------------------ADAYPTVDYAFQYDGVNDFPKYPLNVFATA
MMAR_0371|M.marinum_M TPA-----------------DTIYPTSIYTHEYDGFADFPRYPLNIVSDL
MUL_2440|M.ulcerans_Agy99 TP------------------DNYYTTDVYTLEYDGFADFPRYPPNFVSDL
TH_4068|M.thermoresistible__bu GDA-----------------VLVPVKLDATVEFDPLSDFPAWKN-PFSLA
MSMEG_0200|M.smegmatis_MC2_155 TSGDSLLNNIQLLGLTVGGANLIPIKVDATAEYLPLSDFAAWPN-PFTMT
MAB_0974|M.abscessus_ATCC_1997 TSG---------------ADAKASKIERNEHEGKTADKAAEVPKAEHETK
: . .
Mb2640|M.bovis_AF2122/97 NAIAGILFLHSGLIALPPDLASG----VVQPVS-----------------
Rv2608|M.tuberculosis_H37Rv NAIAGILFLHSGLIALPPDLASG----VVQPVS-----------------
MMAR_0371|M.marinum_M NAIAGIAFVHTDTPTINPETLPPGDLIKLDTSA-----------------
MUL_2440|M.ulcerans_Agy99 NAIMGIYYVHTQYPTLTAAQVAT----AFTLPT-----------------
TH_4068|M.thermoresistible__bu NSAAALVFPTYILRGTDIDNLDDTVGRVLEPVLGSVLGNVLSAVIGDGVG
MSMEG_0200|M.smegmatis_MC2_155 NNVAAALFPTYILRNQSIPGVITDLTGQVVGQLLG---------------
MAB_0974|M.abscessus_ATCC_1997 PGAASEETPKTDPAKEVVEPKVD---------------------------
.
Mb2640|M.bovis_AF2122/97 ------------------------------------------SPDVLTTY
Rv2608|M.tuberculosis_H37Rv ------------------------------------------SPDVLTTY
MMAR_0371|M.marinum_M ------------------------------------------DYTGNTSY
MUL_2440|M.ulcerans_Agy99 ------------------------------------------EGATMTTY
TH_4068|M.thermoresistible__bu VDVSTELLGFPVILPLNLSRDLLLDLAGDLLPDEFALDIPDEGFEALNEY
MSMEG_0200|M.smegmatis_MC2_155 ----------------------------DLADYVADPGDDPTKGPKLNIY
MAB_0974|M.abscessus_ATCC_1997 ------------------------------------------PAKVVESK
Mb2640|M.bovis_AF2122/97 ILLPSQDLPLLVPLRAIPLLG---------NPLADLIQPDLRVLVELGYD
Rv2608|M.tuberculosis_H37Rv ILLPSQDLPLLVPLRAIPLLG---------NPLADLIQPDLRVLVELGYD
MMAR_0371|M.marinum_M YLIHTERLPLLEPLRFIPVVG---------NPLADLLQPDLTTIVNLGYG
MUL_2440|M.ulcerans_Agy99 HMIPTENLPLLEPLRGVPFIG---------NTLADLVQPDLKVLVNLGYG
TH_4068|M.thermoresistible__bu LTLRSGALPLLEPFRIPVDLLNIATGGNFSNPFADAVEDALRILVNLGYT
MSMEG_0200|M.smegmatis_MC2_155 YTLDAKSLPLLEPTYLAVDVINLFTGLNLNNPIGTALSPALTTLVNLGYT
MAB_0974|M.abscessus_ATCC_1997 TDPTKAVEPKADPTKVVEPQV-----------VEPKVDPAKAVEPKTDPA
* * . :. : .
Mb2640|M.bovis_AF2122/97 R------TAHQDVPS---------PFGLFPDVDWAEVAADLQQGAVQGVN
Rv2608|M.tuberculosis_H37Rv R------TAHQDVPS---------PFGLFPDVDWAEVAADLQQGAVQGVN
MMAR_0371|M.marinum_M DPRYGYSTAPANIET---------PFGLFPEVDPKVVAQQLVIGTQQGFH
MUL_2440|M.ulcerans_Agy99 DPNYGYSTGPANVPT---------PFGLFPDVAPATVFDALVAGTQQGIS
TH_4068|M.thermoresistible__bu DVDQDNGYRRTHDQAGLNADGGGVPFGTRPDIDWARVPEDVVTALVAGIQ
MSMEG_0200|M.smegmatis_MC2_155 DVRRVETADGVEYVRDFDDSDIPTAFGSFPDVEWAKVPGDVVTQLVRGVQ
MAB_0974|M.abscessus_ATCC_1997 KAVEPKADAAAEPAK---------PESSKPESSKAEVAKPVTAKPETKAQ
. . . *: * :
Mb2640|M.bovis_AF2122/97 ---------------------DALSGLGLPPPWQ----------------
Rv2608|M.tuberculosis_H37Rv ---------------------DALSGLGLPPPWQ----------------
MMAR_0371|M.marinum_M ---------------------SAAHDLVAPQPSP----------------
MUL_2440|M.ulcerans_Agy99 ---------------------DAAADIGAWQLPS----------------
TH_4068|M.thermoresistible__bu REFLGGGIPGINDAPRRNPIADVLTALGLPASLEGLRDLGDLIDRFPGFG
MSMEG_0200|M.smegmatis_MC2_155 KAVGDG---LVNQSPVPSPLTTLLGLLGLGNALP----------------
MAB_0974|M.abscessus_ATCC_1997 P--------------------AKPESAGPVKVTR----------------
Mb2640|M.bovis_AF2122/97 ------------------PALPRLF-------------------------
Rv2608|M.tuberculosis_H37Rv ------------------PALPRLF-------------------------
MMAR_0371|M.marinum_M ------------------PTPRLFLDIPNPLASIALPPPASLVAP----T
MUL_2440|M.ulcerans_Agy99 ------------------LPDISLSGISNALGSDPWSALSNATLPTLSVS
TH_4068|M.thermoresistible__bu DIVDGVFGGGSGGFSGGLPSATSLPDTDAVRAVTLIQPAATESATPQSLP
MSMEG_0200|M.smegmatis_MC2_155 ----------SGGSVLNLPDLNGLLPTAGTTNVAARQSEPNTKFEPQAIT
MAB_0974|M.abscessus_ATCC_1997 ---------------------DSLKSTPGETGTTGGTKTTEGSKGSVTDS
:
Mb2640|M.bovis_AF2122/97 --------------------------------------------------
Rv2608|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0371|M.marinum_M SIDGFINALQTANTTVTNAFTDVLATSYAKLLPTADIINAGLTTVPSYNL
MUL_2440|M.ulcerans_Agy99 TIENAIKGVQTATTDIANTISFDATTAYATLLPTADVVNAMVTTLPAYNL
TH_4068|M.thermoresistible__bu VQETVPTGSRTVTAEKAVTPAPPAPPAQAASARTDDAADDAGDTVTPGKR
MSMEG_0200|M.smegmatis_MC2_155 ETKATDPDTTVLNLPSPQEKTTVPEPTKKVGGEVKKVVADIDEARAEIEA
MAB_0974|M.abscessus_ATCC_1997 KTPAASTDTKVHDGLKPAVGAKPDKPADKPSTEKSSSEKSGSSSEGSSHS
Mb2640|M.bovis_AF2122/97 --------------------------------------------------
Rv2608|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0371|M.marinum_M NLF--LDGIEQAVDGDPIG----------LINAIGYPIAADAALLGLAGG
MUL_2440|M.ulcerans_Agy99 KLF--LDGILQVLDGDPAG----------LIYALGAPIAADTALVTLLAG
TH_4068|M.thermoresistible__bu TRLNVITGRGDTVTESPVRGATTDNRVGDSLRDVRSPVTKTPQQSRPGRQ
MSMEG_0200|M.smegmatis_MC2_155 KVKKANERAKASAEKARERTQKAVKDAQDRVNKIADNGRKQIKAVADGVE
MAB_0974|M.abscessus_ATCC_1997 SESKSHSSEGKSHSGSKD--------------------------------
Mb2640|M.bovis_AF2122/97 --------------------------------------
Rv2608|M.tuberculosis_H37Rv --------------------------------------
MMAR_0371|M.marinum_M LEALVLLGAIVTDF------------------------
MUL_2440|M.ulcerans_Agy99 FNLYAYLYAFNKILPGVL--------------------
TH_4068|M.thermoresistible__bu ISRPAATDSGRSARSSTSSATP----------------
MSMEG_0200|M.smegmatis_MC2_155 KAVKDTKQAVKKATAKPTKKTQAGSQNNDNDKKDKDAA
MAB_0974|M.abscessus_ATCC_1997 --------------------------------------