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M. thermoresistible (build 8) TH_3952 (-)

annotation: MscS mechanosensitive ion channel
coordinates: 428162 - 429115
length: 318

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3952--100% (318)MscS mechanosensitive ion channel
M. thermoresistible (build 8)TH_2153-2e-4032.47% (308) POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN
M. thermoresistible (build 8)TH_2299-7e-0827.13% (129) PROBABLE CONSERVED TRANSMEMBRANE PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3131c-4e-3832.76% (293) transmembrane protein
M. gilvum PYR-GCKMflv_2744-1e-13276.62% (308) MscS mechanosensitive ion channel
M. tuberculosis H37RvRv3104c-4e-3832.76% (293) transmembrane protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1411-3e-8952.70% (315) putative mechanosensitive ion channel
M. marinum MMMAR_1528-1e-3933.33% (306) transmembrane protein
M. avium 104MAV_4005-1e-3838.29% (222) transporter, small conductance mechanosensitive ion channel
M. smegmatis MC2 155MSMEG_1315-1e-11973.06% (297) transporter, small conductance mechanosensitive ion channel
M. ulcerans Agy99MUL_2411-2e-3933.01% (306) transmembrane protein
M. vanbaalenii PYR-1Mvan_3795-1e-13078.07% (301) MscS mechanosensitive ion channel

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2744|M.gilvum_PYR-GCK          ----MDV-----SSLAFEWTDTSRHWLIEVPIRIVVYIAVALVIRYLVHR
Mvan_3795|M.vanbaalenii_PYR-1       ----MDV-----SLLAFEWTDTSRHWLIEVPIRIVAYLTVALVIRFVVHR
TH_3952|M.thermoresistible__bu      ----MDLGFTPATWVALEWTETSQHWLIEVPIRIVAYLVAALIARLVLHR
MSMEG_1315|M.smegmatis_MC2_155      ----MDV-----YNVAFEWTDTNRHWFIEVPIRITAYIVIVLIARYVLHR
MAB_1411|M.abscessus_ATCC_1997      -----------MSDLAIQLSESGRDWLIHRPVDIAIYVVLALAVRYVLHR
Mb3131c|M.bovis_AF2122/97           MTTSGTVLAT---SIAQHWHNFWRGEIGDWILNRGLRIVMLLIAAVLAAR
Rv3104c|M.tuberculosis_H37Rv        MTTSGTVLAT---SIAQHWHNFWRGEIGDWILNRGLRIVMLLIAAVLAAR
MMAR_1528|M.marinum_M               MTTNTTAFALATFSPAQYWHDFWRGQIGEWIITRGLRIVMVLIAAVLAAR
MUL_2411|M.ulcerans_Agy99           MTTNTTAFALATFSPAQYWHDFWRGQIGEWIITRGLRIVMVLIAAVLAAR
MAV_4005|M.avium_104                ---------------------------------------MVLIAAVLAAR
                                                                             *    :  *

Mflv_2744|M.gilvum_PYR-GCK          MIDRATTGRTRKNRGGG-------------------EDARPQRTPPLVRR
Mvan_3795|M.vanbaalenii_PYR-1       MIDRATTSRTRKDK-----------------------DAAGARTPPLVRK
TH_3952|M.thermoresistible__bu      MIDRATG---RMGRS----------------------DGHPHTRPLLLRP
MSMEG_1315|M.smegmatis_MC2_155      LIDRATTGRSHQERE---------------------EGKPPSRRPPLLRY
MAB_1411|M.abscessus_ATCC_1997      AIDRLVQGARRPESAEHPRRQWWAFLRRGRDLGESDRLDETARLPARTRT
Mb3131c|M.bovis_AF2122/97           FVTWLANRVTRRLDLG----------------------------------
Rv3104c|M.tuberculosis_H37Rv        FVTWLANRVTRRLDLG----------------------------------
MMAR_1528|M.marinum_M               FVTWVAKRVTQRLDLG----------------------------------
MUL_2411|M.ulcerans_Agy99           FVTWVAKRVTQRLDLG----------------------------------
MAV_4005|M.avium_104                FVNWVALQVSRQLTTG----------------------------------
                                     :   .    :                                       

Mflv_2744|M.gilvum_PYR-GCK          LRDRVPSSTTSEQIIARRQQRAQTIGSVLKSTVSIVLLVWVVLAVLNVVG
Mvan_3795|M.vanbaalenii_PYR-1       LRDRVPSSASSEQVIARRQQRAQTIGSVLKSTVSIVLLVWVVLAVLNVLG
TH_3952|M.thermoresistible__bu      LRDRKSSGATSQKIAERRQQRAKTIGSVLKSTVSIVLIIWVSLAILSVLG
MSMEG_1315|M.smegmatis_MC2_155      LRERAPAAASSSQTAKRRQQRAQTIGSVLKSTVSIVLLGWMVLGVLSVLG
MAB_1411|M.abscessus_ATCC_1997      LRGRAQDPARDARRRKRRAQRAQTLGSVLKSAVSFLVLVWVILQSLAILG
Mb3131c|M.bovis_AF2122/97           ------FTESDALVRSEATKHRQAVASVISWVSIVLIYVVVVYEVIDVLP
Rv3104c|M.tuberculosis_H37Rv        ------FTESDALVRSEATKHRQAVASVISWVSIVLIYVVVVYEVIDVLP
MMAR_1528|M.marinum_M               ------FTESDALVRSEVSKHRQAVASVISWVSIVLIYVIVLYEIVDILP
MUL_2411|M.ulcerans_Agy99           ------FTESDALVRSEVSKHRQAVASVISWVSIVVIYVIVLYEIVDILP
MAV_4005|M.avium_104                ------FVESDALVRSEASKHRQAVASVISWVSVVIIGIWVMLQIASILQ
                                              .     .  :: :::.**:. .  .::   :      :: 

Mflv_2744|M.gilvum_PYR-GCK          VNIAPFIASAGVVGLAIGFGAQNLVRDFVTGVFMLLEDQYGVGDTVDLG-
Mvan_3795|M.vanbaalenii_PYR-1       VNIAPFIASAGVVGLAIGFGAQNLVRDFVTGVFMLLEDQYGVGDTVDLG-
TH_3952|M.thermoresistible__bu      VNIAPFIASAGVVGLAIGFGAQNLVRDFVTGVFMLLEDQYGVGDIVDLG-
MSMEG_1315|M.smegmatis_MC2_155      VNIAPLIASAGVAGVAIGFGAQNLVRDFVTGMFMLLEDQYGVGDTVDLG-
MAB_1411|M.abscessus_ATCC_1997      VNVAPFIASAGIVGVALGFGAQNLVRDFITGIFMLFEDQYGVGDVVDVG-
Mb3131c|M.bovis_AF2122/97           VPVGALVGPAAVLGAALGFGAQRLVQDLLAGFFIIVEKQYGFGDLVELSM
Rv3104c|M.tuberculosis_H37Rv        VPVGALVGPAAVLGAALGFGAQRLVQDLLAGFFIIVEKQYGFGDLVELSM
MMAR_1528|M.marinum_M               FPVGSLVGPAAVLGAALGFGAQRLVQDLLAGFFIIVEKQYGFGDLVELSM
MUL_2411|M.ulcerans_Agy99           FPVGSLVGPAAVLGAALGFGAQRLVQDLLAGFFIIVEKQYGFGDLVELSM
MAV_4005|M.avium_104                FSVGGLVAPATVVGAALGFGAQQLVKDLLSGFFILAERQYGFGDLVTLTV
                                    . :. ::..* : * *:*****.**:*:::*.*:: * ***.** * :  

Mflv_2744|M.gilvum_PYR-GCK          -----EAVGEVESVGLRITTVRDIDGTLWYVRNGEIARVGNMSQEYAVAR
Mvan_3795|M.vanbaalenii_PYR-1       -----EAVGEVESVGLRITTVRDIDGTLWYVRNGEIARVGNMSQEYAVAR
TH_3952|M.thermoresistible__bu      -----EVVGQVETVGLRITTVRDIDGTLWYVRNGEILRVGNMSQEYAVAR
MSMEG_1315|M.smegmatis_MC2_155      -----AAVGQVESVGLRITTLRDIDGTLWYVRNGEIARVGNMSQDYAVAR
MAB_1411|M.abscessus_ATCC_1997      -----DAVGTVESVGLRITTVRDLQGTLWYVRNGGIARVGNFSQDYAVAF
Mb3131c|M.bovis_AF2122/97           VGSPENAAGTVEDVTLRVTKLRSSEGEVFTVPNGNIVKSVNLSKDWARAV
Rv3104c|M.tuberculosis_H37Rv        VGSPENAAGTVEDVTLRVTKLRSSEGEVFTVPNGNIVKSVNLSKDWARAV
MMAR_1528|M.marinum_M               VGSPENAAGTVEEVTLRVTKLRSSDGEVYTVPNGNIVKSINLSKDWARAV
MUL_2411|M.ulcerans_Agy99           VGSPENAAGTVEEVTLRVTKLRSSDGEVYTVPNGNIVKSINLSKDWARAV
MAV_4005|M.avium_104                VAATE-ASGTVENVTLRVTRLRSPDGEVLTIPNGQIVKVVNLSKDWARAV
                                          . * ** * **:* :*. :* :  : ** * :  *:*:::* * 

Mflv_2744|M.gilvum_PYR-GCK          IEVPVALSADIERAEQVAVEAAEAAVAEKSLAGKVLGEPEMLGVQELSPD
Mvan_3795|M.vanbaalenii_PYR-1       IEVPVALTADVDRAEQVAHEAAQEAVADPALAGKVIGEPEMLGVQELSPD
TH_3952|M.thermoresistible__bu      VEVPVALTVDVDRAEQVAVEAAERALADESLADKVLGKPEMLGIQELSPD
MSMEG_1315|M.smegmatis_MC2_155      VEVPVAVTTDLNRAEEIALQAAEEALADPKVSDKTLGEPEMLGVQDFSAD
MAB_1411|M.abscessus_ATCC_1997      LQIPLSYSADVDLACTIALEAAREAVAEEALRDDVIGAPEMLGIDGITAD
Mb3131c|M.bovis_AF2122/97           VDIPVPTSADLGRVNEVLHQECEHARHDSLLGELLLDEPTVMGVERIEVD
Rv3104c|M.tuberculosis_H37Rv        VDIPVPTSADLGRVNEVLHQECEHARHDSLLGELLLDEPTVMGVERIEVD
MMAR_1528|M.marinum_M               IDIPVPTGADLNRVNEVLHRECQHAREDAILGDLLLDEPTVMGVEKLEMD
MUL_2411|M.ulcerans_Agy99           IDIPVPTGADLNRVNEVLHRECQHAREDAILGDLLLDEPTVMGVEKLEMD
MAV_4005|M.avium_104                VDIPVSTSADLNRVNEVLHQECDRAMDNPVLGQLLLDSPTVMGVESIEVD
                                    :::*:.  .*:  .  :  . .  *  :  :    :. * ::*:: :  *

Mflv_2744|M.gilvum_PYR-GCK          LIKLRMTVKVRPNAQWAVQRRLRRAILQAYDEHGIALPYPNGRVHAVGE-
Mvan_3795|M.vanbaalenii_PYR-1       LIKLRMTVKVRPNAQWAVQRKLRRAILRAYDEHGIDLPYPGGRMQVAAAS
TH_3952|M.thermoresistible__bu      LLTLRMTVKTRPNEQWAVQRRLRREILRAYDEHGIDLPYPRGRIHAVVGE
MSMEG_1315|M.smegmatis_MC2_155      HVTLRMTVKTRPNAQWSVQRRLRREILRAYDEHEIYAPNA----------
MAB_1411|M.abscessus_ATCC_1997      AISLRLTVAVRANAQWAVERELRRRILIAFDENGIRPLYLDGLSSGTVET
Mb3131c|M.bovis_AF2122/97           TVTLRLVARTLPGKQFEAGRQLRVLVIRALTRAGIVTAADARAAV-----
Rv3104c|M.tuberculosis_H37Rv        TVTLRLVARTLPGKQFEAGRQLRVLVIRALTRAGIVTAADARAAV-----
MMAR_1528|M.marinum_M               TVTLRLVARTLPGKQFAAGRQLRVLVIRALTGAGIITPADAQAAVGVMAH
MUL_2411|M.ulcerans_Agy99           TVTLRLVARTLPGKQFAAGRQLRVLVIRALTGAGIITPADAQAAVGVMAH
MAV_4005|M.avium_104                TVTLRLVARTLPGKQFEVGRQLRVLVIRALARAGIVTAADARVGLVEDAS
                                     :.**:.. . .. *: . *.**  :: *     *               

Mflv_2744|M.gilvum_PYR-GCK          ----------------------
Mvan_3795|M.vanbaalenii_PYR-1       E---------------------
TH_3952|M.thermoresistible__bu      SR--------------------
MSMEG_1315|M.smegmatis_MC2_155      ----------------------
MAB_1411|M.abscessus_ATCC_1997      LEKASR----------------
Mb3131c|M.bovis_AF2122/97           -------AESP---EQ------
Rv3104c|M.tuberculosis_H37Rv        -------AESP---EQ------
MMAR_1528|M.marinum_M               PATVSGAADAPAGAEQQR----
MUL_2411|M.ulcerans_Agy99           PATVSGAADAPAGAEQQR----
MAV_4005|M.avium_104                VPAAQAAEQQSDDDVQGAVQKR