For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_3900 (-)

annotation: conserved hypothetical protein
coordinates: 2314461 - 2315846
length: 462

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3900--100% (462)conserved hypothetical protein
M. thermoresistible (build 8)TH_3639-9e-2637.61% (226) PUTATIVE putative conserved hypothetical protein
M. thermoresistible (build 8)TH_3241-4e-2327.89% (380) PUTATIVE putative FHA domain containing protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1919-3e-3533.87% (310) hypothetical protein Mb1919
M. gilvum PYR-GCKMflv_0290-1e-12764.40% (382) hypothetical protein Mflv_0290
M. tuberculosis H37RvRv1887-4e-3533.87% (310) hypothetical protein Rv1887
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4296c-6e-7340.75% (427) hypothetical protein MAB_4296c
M. marinum MMMAR_0602-2e-7343.33% (420) hypothetical protein MMAR_0602
M. avium 104MAV_4824-2e-8346.37% (399) hypothetical protein MAV_4824
M. smegmatis MC2 155MSMEG_0679-1e-12262.31% (390) hypothetical protein MSMEG_0679
M. ulcerans Agy99MUL_1227-1e-6740.50% (400) hypothetical protein MUL_1227
M. vanbaalenii PYR-1Mvan_0590-1e-12062.57% (374) hypothetical protein Mvan_0590

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0290|M.gilvum_PYR-GCK          ---------MDIVLGVSMTPTTVRMVLVEGEKADGVTVDHDTFAVDSVEG
Mvan_0590|M.vanbaalenii_PYR-1       -----------------MTPTTVRMVLVEGEKADGVTVDHDVFHVDSADG
MSMEG_0679|M.smegmatis_MC2_155      ---------MDIVLGVSMTPTTVRMVLVEGENADGITVDHDVFDVTAVED
TH_3900|M.thermoresistible__bu      ---------VDIVLGVSMTPTTVRMVLVEGEKADGVTVDHDVFDISAVDG
MMAR_0602|M.marinum_M               MVEQVLGELLDTVLGVSVAPTAVRLVLVEGENGDGALVDEDAFDVSGDGD
MAV_4824|M.avium_104                ---------MDTVLGVSMAPTAVRMVLVEGENGDGATVDEDNFDVATSED
MUL_1227|M.ulcerans_Agy99           ---------MDIVLGVSMEPGAVRLVLVEGIDADGVTVEEDTFELDTAD-
MAB_4296c|M.abscessus_ATCC_199      ---------MDVVLGVSMTPTTARLVLVEGAGADGRIVDTDTIVVSEGEG
Mb1919|M.bovis_AF2122/97            ---------MDTVLGLSITPTTLGWVLAEGHGADGAILDRNELELHSGRN
Rv1887|M.tuberculosis_H37Rv         ---------MDTVLGLSITPTTLGWVLAEGHGADGAILDRNELELHSGRN
                                                     : * :   **.**  .**  :: : : :     

Mflv_0290|M.gilvum_PYR-GCK          SAN--AAEHVVSAVLGTRESAETGGHHLKSIGVTWSDHA--EATALRDAL
Mvan_0590|M.vanbaalenii_PYR-1       SAN--VAEHVVSAIQGTKESAETGGHHLRSIGVTWSDHT--EATALRDAL
MSMEG_0679|M.smegmatis_MC2_155      AATMSAADQVVAAILGTQESADAGGHHLKSIGVTWSDHS--DASALRDSL
TH_3900|M.thermoresistible__bu      SATPSAAEQVVAAVLGTQESAAAGGHRLISIGVAWSDHA--EAAALREAL
MMAR_0602|M.marinum_M               AATIGAAEQVISAILGTREGASEGGYQLTSTGVTWRDPA--QAAALRDVL
MAV_4824|M.avium_104                AATVTASDQVLSAILGTRQGAAEGGYQLASTGVTFTDPV--EAAALRDKL
MUL_1227|M.ulcerans_Agy99           -RSQGAPAAAVAALIGTREGAIEGGYRLMSAGVTWTDPT--DVAALRAEL
MAB_4296c|M.abscessus_ATCC_199      TTS----EQVLSAIVGTRDGMLDGGHNLVSTGVVWSDHA--EAAELRDSL
Mb1919|M.bovis_AF2122/97            AQAIHTAEQLAAEVLLAHEVAAAGDHRLRVIGVTWNAEASAQAALLVESL
Rv1887|M.tuberculosis_H37Rv         AQAIHTAEQLAAEVLLAHEVAAAGDHRLRVIGVTWNAEASAQAALLVESL
                                               : :  :::    *.:.*   **.:      :.: *   *

Mflv_0290|M.gilvum_PYR-GCK          AAHGIDDVMLVSESHAAASLAQAVGRAVDYDTTALLFVDRDTATLSVVKT
Mvan_0590|M.vanbaalenii_PYR-1       ATHGIDDVMLVSEGHAAASLAQAVGRAVGYDTTALLFVDRDTATLSVVQT
MSMEG_0679|M.smegmatis_MC2_155      TAHGIDDVMLVSEGHAAAALAQAVGRAVGYDTTALLFIDRDAATLSVVQT
TH_3900|M.thermoresistible__bu      AARGLDDVMLVSELHAAGALAQAVGRRVGYDTTALFFIERDTATMAVVQT
MMAR_0602|M.marinum_M               ARRKIENVVLVSAFLAAAALAHAVGSETNYAQTALLFIEPEAATLAVVDS
MAV_4824|M.avium_104                AAHKVENVMLVSAFLAAAALAQAVGHRTNYAHTALLYIEPDTATLAVVDS
MUL_1227|M.ulcerans_Agy99           AGHDVGSVMLVSPLLAAAALAQTVGCALDYEYIAMLFVEADSATLAVVDI
MAB_4296c|M.abscessus_ATCC_199      ASRGIDGVEFFSALHAGGALAKAASSVTGYDKSALLVIEPQTATLAVVDS
Mb1919|M.bovis_AF2122/97            TGAGFDNVVPVRRLRAIETLAQAIAPVIGYEQIAVCVLEHESATVVMVDT
Rv1887|M.tuberculosis_H37Rv         TGAGFDNVVPVRRLRAIETLAQAIAPVIGYEQIAVCVLEHESATVVMVDT
                                    :   . .*  .    *  :**:: .   .*   *:  :: ::**: :*. 

Mflv_0290|M.gilvum_PYR-GCK          DDGSVVKVLSRSLHSADAMAVLAEMAAAIDTRTQDAPPQGIFVVGSGVDI
Mvan_0590|M.vanbaalenii_PYR-1       DDGSVVKVLSRSLHSADAMAVLTEMAEAVAA--QEAPPQGMFVVGSGVDI
MSMEG_0679|M.smegmatis_MC2_155      EDGSVVKVLGSSLHSTDAMAVLSDMAAAVVA--QETPPDGMFIVGSGVDV
TH_3900|M.thermoresistible__bu      DDGSVVKVLSRDLHNADAMATLTEMALTVDG--QDSPPQGMFLIGSGVDI
MMAR_0602|M.marinum_M               ADGSVTDIHRLSLSDDDDTAVGQLTELISQAESLPTRPDAVFLVGSGIDL
MAV_4824|M.avium_104                ADGSIADVRRQPLPEDDEAAVAELASMVSNAENLETRPDAVFVVGSGIDI
MUL_1227|M.ulcerans_Agy99           GDGSIVDLHRRSLG--AESTAADLTSLVGGLATAQSVAEGVFVVGCGVDI
MAB_4296c|M.abscessus_ATCC_199      ADGSIVGLASEPLITGVTSGVLANLVNPLKG--KENAPDGVFLLGLGTDV
Mb1919|M.bovis_AF2122/97            HDGKTQIAVKHVCRGLSGLTSWLTGMFGRDA----WRPAGVVVVGSDSEV
Rv1887|M.tuberculosis_H37Rv         HDGKTQIAVKHVCRGLSGLTSWLTGMFGRDA----WRPAGVVVVGSDSEV
                                     **.                                 . .:.::* . ::

Mflv_0290|M.gilvum_PYR-GCK          SSVKDHLKHLVAVPIHAPDDAELALARGAALASASAPAFEATTVGLAYSQ
Mvan_0590|M.vanbaalenii_PYR-1       SSVKAHLEHLVSLPVSAPDDAELALARGAALASAAAPAFEATTVGLAYSQ
MSMEG_0679|M.smegmatis_MC2_155      SSVKEHLQHLVSMPVNAPEEPELALARGAALASATAPALEASTVGLAYSQ
TH_3900|M.thermoresistible__bu      SELKAHLDKLLRLPVHAPEESDLALCRGAALAAANAPTFEPSTVGLAYSQ
MMAR_0602|M.marinum_M               PLIKPTLEASTTLPVTAAEEPDTALARGAALAAASSPLFASSTAAQAWAQ
MAV_4824|M.avium_104                PLIKPALEAATTLPLTAPEEPDTALARGAALASAHAPLFASSTAALAYAQ
MUL_1227|M.ulcerans_Agy99           VALKPVLEAATSLVVSVPEEPDMALARRAALASANAPLFASSTSALAYAL
MAB_4296c|M.abscessus_ATCC_199      SDLAESLGDAIALPVNSPDQPELALARGAALASAQEPDFEASTALLGQAY
Mb1919|M.bovis_AF2122/97            SEFSWQLERVLPVPVFAQTMAQVTVARGAALAAAQSTEFTDAQLVADSVS
Rv1887|M.tuberculosis_H37Rv         SEFSWQLERVLPVPVFAQTMAQVTVARGAALAAAQSTEFTDAQLVADSVS
                                      .   *     : :     .: ::.* ****:*  . :  :        

Mflv_0290|M.gilvum_PYR-GCK          DPDG-----------------TTAG---------SVFAGLAGAQTQMAPV
Mvan_0590|M.vanbaalenii_PYR-1       DPDG-----------------TTAG---------SVYAGLAGADTQLAPV
MSMEG_0679|M.smegmatis_MC2_155      DPDG-----------------PTAG---------SAYA-LAGLDTQLAPA
TH_3900|M.thermoresistible__bu      VPDGGPTVPASVYAAGFGADAATAGGHP-----YAAYAAFAGAQTQLASI
MMAR_0602|M.marinum_M               DPGS-----------------GVLY----------SHAPYGLDAAYFDDV
MAV_4824|M.avium_104                DPGT-----------------GAINPLAVAPGYFETPADAGADGLAYSAV
MUL_1227|M.ulcerans_Agy99           DPGT-----------------GEVN-------------PRALAPSYLDVC
MAB_4296c|M.abscessus_ATCC_199      SLEG------------------PTG------------TGFAHPDAVTESA
Mb1919|M.bovis_AF2122/97            QPTV----------------------------------------------
Rv1887|M.tuberculosis_H37Rv         QPTV----------------------------------------------
                                                                                      

Mflv_0290|M.gilvum_PYR-GCK          G------GDVPVDEFAP---TEMRPVDEERKPFLLVGSALTSLFVVGVVA
Mvan_0590|M.vanbaalenii_PYR-1       G------AEDVVDEFAP---TEMRPVDEGRKPFLLVGSALTSLFVIGVAA
MSMEG_0679|M.smegmatis_MC2_155      GSDLGSLVDGGVDELDPAVFNEVAAADEERKPFLLVGSALTSVFVIGVVA
TH_3900|M.thermoresistible__bu      G--------GAAPSPVP----GEPPVDEDRKPFLLVGSALTSIFVVGVVA
MMAR_0602|M.marinum_M               S-DQLG---TGQQALAY---SAVPEEQHERRPFALLASIMGSIFIIGVGA
MAV_4824|M.avium_104                P-DDPDEFFTGTQAAAT---ELVDADYADRSSFKLVGSAVAAIFVIGVVA
MUL_1227|M.ulcerans_Agy99           ANADRGAGSLAYSALAD---DGEDAVEGRRRPLVLAGSAMLGIAAFAAGL
MAB_4296c|M.abscessus_ATCC_199      G--------EANTELREF--EDFDDQPAERKPFLLVGAPLLLVFGICSIA
Mb1919|M.bovis_AF2122/97            ---------------------------APRRSRHYAGAAAALAAAAVTFV
Rv1887|M.tuberculosis_H37Rv         ---------------------------APRRSRHYAGAAAALAAAAVTFV
                                                                 * .    .:            

Mflv_0290|M.gilvum_PYR-GCK          LVISLAISIRPTADQRPS-PAQAAIVPS---SQAPTAEPAP---------
Mvan_0590|M.vanbaalenii_PYR-1       LVVSLAISIRPTADQRPS-PAQSAIVP----SQLPAPAPAP---------
MSMEG_0679|M.smegmatis_MC2_155      LVISLAVSIRPTVDQRPA-PAQGAVVPTAPVAKAPAPAPAP---------
TH_3900|M.thermoresistible__bu      LVVSLAVSIRPTVDQRPS-PADSALAPG----VAAPVQPET---------
MMAR_0602|M.marinum_M               LAVSLAVSIRSEPGTRPD-PGQSVVTHL---PAPAHAAPAPQPQAPAPQA
MAV_4824|M.avium_104                LVVSLAIAIRPTANVRPS-PNQNVVVAP---TRPAPAAPAP---------
MUL_1227|M.ulcerans_Agy99           MVVTLTSDVRPAAATQPS-PREGVLTPA---SPAAPPKTATP--------
MAB_4296c|M.abscessus_ATCC_199      LAVSLTVTVRSTVDQGPSSPDRGVVQNPLPAEAPKQAAPPPSP-----VE
Mb1919|M.bovis_AF2122/97            ASLSLAVGIQLAPHNDTGTAKHGAHKPTPRIAKAVAPAVPP---------
Rv1887|M.tuberculosis_H37Rv         ASLSLAVGIQLAPHNDTGTAKHGAHKPTPRIAKAVAPAVPP---------
                                      ::*:  ::      .  .   .                .         

Mflv_0290|M.gilvum_PYR-GCK          ------ARQEAAQIPPPPSTAETIKPPVPVVQQAP---QQAPRTVFVEQA
Mvan_0590|M.vanbaalenii_PYR-1       ------ARQEAADVPANPPSAETIKPPIPVVQEAP---QQAPRTVYVEQA
MSMEG_0679|M.smegmatis_MC2_155      ------EAKPVQEAPPPAPPPETIKAPVPVVQEAPQ-PQAPPRTVYVEQP
TH_3900|M.thermoresistible__bu      ------VPEALXXXPPHPSPAPNVKP----LRCAG------GFSAVVART
MMAR_0602|M.marinum_M               PAPQAQAPAPQAQVPAPAPAPQA-PAPRAPAPQAP--APQAQVPAPKAPA
MAV_4824|M.avium_104                ------APAPEAPAPAPAAAPQA-PAP----------APEAPAPAPAAPA
MUL_1227|M.ulcerans_Agy99           -----VPAKAPAQVPAPGPAPAASPVP-----VAA--PPSVVQPPPVVRA
MAB_4296c|M.abscessus_ATCC_199      APAPAVSPAPVQQVVAPAPQHNPAPAPKQVAPAPVQAAPQAPAPAPEAPA
Mb1919|M.bovis_AF2122/97            ------PPTVTPPVPARAPRPAAQHEP-----------PARVTSGEALTE
Rv1887|M.tuberculosis_H37Rv         ------PPTVTPPVPARAPRPAAQHEP-----------PARVTSGEALTE
                                                   .  .                        .      

Mflv_0290|M.gilvum_PYR-GCK          PAPAPAAPAPAPAPVAPPPAPAP--IPAAPPVVAPVVLPPPVVVLPRPQW
Mvan_0590|M.vanbaalenii_PYR-1       PAPA----VPAPAPAAPPPAPA----PAAPPVVAPVVVPPPVIVLPRPQW
MSMEG_0679|M.smegmatis_MC2_155      QAPAPAPAAPPPAPEAPPPAPVAPVLPAPAPVYQPPGYIPPVVVLPR---
TH_3900|M.thermoresistible__bu      TAPG-------PFPTG----------------------------------
MMAR_0602|M.marinum_M               PVPVPVAQAPVPVPQAPAPVPVPI-------------------------P
MAV_4824|M.avium_104                PAPVQVA--PVPVPEAPAPAPA----------------------------
MUL_1227|M.ulcerans_Agy99           PRPTVVK--PPPQYIAPATQPRR---------------------------
MAB_4296c|M.abscessus_ATCC_199      PAAPAPVPEEQPAPVAPPPAVVPVPIPLFPPVWEPPRRQENPWWPDRDRP
Mb1919|M.bovis_AF2122/97            PNPPEEQ----PNASAPQQDR-----------------------------
Rv1887|M.tuberculosis_H37Rv         PNPPEEQ----PNASAPQQDR-----------------------------
                                      .        *   .                                  

Mflv_0290|M.gilvum_PYR-GCK          NPPRPAWTWPNQ--RPDVDDDSDDSPWTPQKPPR-TPSQP-PTTRPPVPQ
Mvan_0590|M.vanbaalenii_PYR-1       TPPKPAWTWPTQTVEPDEPDEPWQPPWEDDDDDKPTPTLPTQTVVPTRPQ
MSMEG_0679|M.smegmatis_MC2_155      VPSIFRPPWEPQ--RPPQQN-PWNPPWDPPKQAP-KPQWPGSGPGGWDPG
TH_3900|M.thermoresistible__bu      --------WSRR------------------------------------SA
MMAR_0602|M.marinum_M               QAPAPAPEAPVP-----------------------------------APV
MAV_4824|M.avium_104                -----APPPPPP-----------------------------------AVA
MUL_1227|M.ulcerans_Agy99           ---TPAPQAPAP-----------------------------------TPV
MAB_4296c|M.abscessus_ATCC_199      RYTPPAQTQQPP----------------------------IISIPGLPPI
Mb1919|M.bovis_AF2122/97            --------------------------------------------------
Rv1887|M.tuberculosis_H37Rv         --------------------------------------------------
                                                                                      

Mflv_0290|M.gilvum_PYR-GCK          VPQVPQIPQVPQVPQVPQWPGAGSGSGSGSGSSSGSGSSRGDSGSRGGDS
Mvan_0590|M.vanbaalenii_PYR-1       VPTVPQVPTVPQVPQQPQWPGSGSGAGSGSGSSSGSYGGSGSYGGGRGDS
MSMEG_0679|M.smegmatis_MC2_155      PGRGSDNGPGRGGGDNDWNPGRGSG-GPGRGDSGNSGWNPGSGGGRNGGG
TH_3900|M.thermoresistible__bu      AAELVSHATVRCS-------------GDGPGSAGVPGWDPDPSIKADGGR
MMAR_0602|M.marinum_M               PIPVPIQIPLPQIF--------------GPGGGGGFPGGDDDRGGRGGG-
MAV_4824|M.avium_104                PIPVPIPLPIPGLG--------------GPGFGGPPGHGGGDGGGHGGGG
MUL_1227|M.ulcerans_Agy99           QAPAPEVPPPVAVP--------------EPAPAPPVPALVVER-------
MAB_4296c|M.abscessus_ATCC_199      GGGDSDRGSHGGSRGGSGRGGWGDDGDSRGGSDSGSRGGWGDNGGSRGGW
Mb1919|M.bovis_AF2122/97            NDSQPITRVLEHIP--------------GAYGDSAPPAE-----------
Rv1887|M.tuberculosis_H37Rv         NDSQPITRVLEHIP--------------GAYGDSAPPAE-----------
                                                                                      

Mflv_0290|M.gilvum_PYR-GCK          SSGRG-SGSGVPGDINGDGCFLIFCGSGRN--------------
Mvan_0590|M.vanbaalenii_PYR-1       GSSRGGSGSGVPGDVNGDGCFLIFCAPGGGRG------------
MSMEG_0679|M.smegmatis_MC2_155      G---GHNGGGHNGGGGGGPVWPFPFGGGHH--------------
TH_3900|M.thermoresistible__bu      HRFRFAVQMTTRCGLIAHP-------------------------
MMAR_0602|M.marinum_M               -RGGRHGGGHGGG--HGRGGFNIPFIPGI---------------
MAV_4824|M.avium_104                FPGFPGGGGHGGGGFPGFGGGHGGFGHH----------------
MUL_1227|M.ulcerans_Agy99           -LVIQNDGVDLAE-------------------------------
MAB_4296c|M.abscessus_ATCC_199      GDSGSSRGGSDSGSRGGWGGNSGSHGGGSGGGSNSGFPWPFGGR
Mb1919|M.bovis_AF2122/97            --------------------------------------------
Rv1887|M.tuberculosis_H37Rv         --------------------------------------------