For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_3835 (-)

annotation: alpha/beta hydrolase fold domain protein
coordinates: 2576696 - 2577988
length: 431

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3835--100% (431)alpha/beta hydrolase fold domain protein
M. thermoresistible (build 8)TH_1904-e-10250.12% (411) peptidase, S9A/B/C families
M. thermoresistible (build 8)TH_2755-8e-6637.90% (409) PUTATIVE Alpha/beta hydrolase fold-3 domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2305lipM0.076.90% (420) esterase LipM
M. gilvum PYR-GCKMflv_0436-1e-10450.37% (405) alpha/beta hydrolase domain-containing protein
M. tuberculosis H37RvRv2284lipM0.076.90% (420) esterase LipM
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2814-7e-1334.58% (107) lipase LipH
M. marinum MMMAR_3429lipM0.077.72% (413) membrane-bound esterase LipM
M. avium 104MAV_2146-0.077.43% (412) alpha/beta hydrolase domain-containing protein
M. smegmatis MC2 155MSMEG_0302-1e-10250.37% (407) peptidase, S9A/B/C families
M. ulcerans Agy99MUL_2704lipM0.077.48% (413) membrane-bound esterase LipM
M. vanbaalenii PYR-1Mvan_0231-1e-10350.86% (409) alpha/beta hydrolase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0436|M.gilvum_PYR-GCK          ---------MPKPRPLLRAAAELLNAANGVQPLARDGYPTIPVFAFGWPT
Mvan_0231|M.vanbaalenii_PYR-1       ---------MPKRRPLLRAVAELLNAANGLRPLARDGYLTIPVFAFGWPT
MSMEG_0302|M.smegmatis_MC2_155      ---------MAK--PLLTASAEVLNAVNAVKPFGRKGYSTVVAFAFGWPT
MMAR_3429|M.marinum_M               MGRAQIIHIIRQFGALGVAAVTAVSTLNAYKPLARKGFLSIWSWMFGLVV
MUL_2704|M.ulcerans_Agy99           MGRAQIIHIIRQFGALGVAAVTAVSTLNAYKPLARKGFLSIWSWTFGLVV
MAV_2146|M.avium_104                MRKARIVHLIRQIGSLTASAVTAASTLNAYRPLARKGYPSLYAWMFGLVV
Mb2305|M.bovis_AF2122/97            MGAPRLIHVIRQIGALVVAAVTAAATINAYRPLARNGFASLWSWFIGLVV
Rv2284|M.tuberculosis_H37Rv         MGAPRLIHVIRQIGALVVAAVTAAATINAYRPLARNGFASLWSWFIGLVV
TH_3835|M.thermoresistible__bu      -MRDRIVHLARQIAAILAALLSLASTVNGYRPLFSKGYPSIFAWGFGLVV
MAB_2814|M.abscessus_ATCC_1997      -----------------------MTATAGIDPIIVK-------------I
                                                             :  .  *:  .              

Mflv_0436|M.gilvum_PYR-GCK          SELSPLYMAGSMADAVRRGIRGDFRGPRGRIALGLTAVAWALLYLIHRRN
Mvan_0231|M.vanbaalenii_PYR-1       SEVSPLYMAGSMLDAIRRGVRGDFRGARGRIALLLTAAAWALLYLIHRRN
MSMEG_0302|M.smegmatis_MC2_155      SENGPLITTVSALDALRRAVRGDYRTTPGRISLLLKAVAWALLYIVHRRN
MMAR_3429|M.marinum_M               TEF-PLQTMASQVGGLLLTAQRLTRPVR-AISWLVAGISALGLLNFNRAG
MUL_2704|M.ulcerans_Agy99           TEF-PLQTMASQVGGLLLTAQRLTRPVR-AISWLVAGISALGLLNFNRAG
MAV_2146|M.avium_104                TEL-PLQTMLSQLGGLALTARRLTRPVR-IIAWLVAGLSALGLLNLSRAG
Mb2305|M.bovis_AF2122/97            TEF-PLPTLASQLGGLVLTAQRLTRPVR-AVSWLVAAFSALGLLNLSRAG
Rv2284|M.tuberculosis_H37Rv         TEF-PLPTLASQLGGLVLTAQRLTRPVR-AVSWLVAAFSALGLLNLSRAG
TH_3835|M.thermoresistible__bu      SEF-PLQTLASQVGGLALTSRGLTRRVR-IFAWSAAAVSALGLLNFNRAG
MAB_2814|M.abscessus_ATCC_1997      LEAVPIQLVSPDGPQASRDAYRAIATAR----------------------
                                     *  *:    .                                       

Mflv_0436|M.gilvum_PYR-GCK          VASQPHFEEPLRDVLG-----DDYQEIAEKAKSSRRRYFGVFPNEVIRRR
Mvan_0231|M.vanbaalenii_PYR-1       VAAQPYFEDPLREALG-----ENYQRIAEAAKSSRRRRVGVFPPDLVRRR
MSMEG_0302|M.smegmatis_MC2_155      RTSRRFFEEPLRSALG-----ADY-AVARRAR----RPGGVIRTSWARHR
MMAR_3429|M.marinum_M               HRADITLKDALDSGLGTDRRAGSAGLWHRPAGPGTAKAPGPLRMLRIYRD
MUL_2704|M.ulcerans_Agy99           HRADITLKDALDSGLGTDRRAGSAGLWHRPAGPGTAKAPGPLRMLRIYRD
MAV_2146|M.avium_104                HRANVPLTDALDSELGADRLTESADLWRRPTGAGTAKTPGLLRMLRIYRD
Mb2305|M.bovis_AF2122/97            RQADAQLTAALDSGLGPDRRTASAGLWRRPAGGGTAKTPGPLRMLRIYRD
Rv2284|M.tuberculosis_H37Rv         RQADAQLTAALDSGLGPDRRTASAGLWRRPAGGGTAKTPGPLRMLRIYRD
TH_3835|M.thermoresistible__bu      HRADRTLTAALDNGLGLHRRTDSEGLWRRPAGGGTAKTPGAVRMLRIYRD
MAB_2814|M.abscessus_ATCC_1997      ------------------------PPWIEVANIEDRTIPGPAGEIPVRIY
                                                                . :        *          

Mflv_0436|M.gilvum_PYR-GCK          YVEKAGTVQYGPLR-VNRADIWRRPDLPRDGKAPVLLQVPGGAWAIGMRK
Mvan_0231|M.vanbaalenii_PYR-1       YVESV--VQYGPLR-VNRADIWRRADLPRDGKAPVLLQVPGGAWAIGMRR
MSMEG_0302|M.smegmatis_MC2_155      YATTT--VRYGPHR-ANLADIWMRPDLPRDGKAPVLLQVPGGAWMIGMRR
MMAR_3429|M.marinum_M               YAHDS-NISYGEYGSANHLDIWRRPDLDLSAKAPVLFQIPGGAWTTGNKR
MUL_2704|M.ulcerans_Agy99           YAHDS-NISYGEYGSANHLDIWRRPDLDLSAKAPVLFQIPGGAWTTGNKR
MAV_2146|M.avium_104                YAHDS-NISYGEFGSANHLDIWRRPDLDLTGRAPVLFQIPGGAWTTGNKR
Mb2305|M.bovis_AF2122/97            YAHDG-DISYGEYGRANHLDIWRRPDLDLTGTAPVLFQIPGGAWTTGNKR
Rv2284|M.tuberculosis_H37Rv         YAHDG-DISYGEYGRANHLDIWRRPDLDLTGTAPVLFQIPGGAWTTGNKR
TH_3835|M.thermoresistible__bu      YAHDG-DISYGPYGSANHLDIWRRPDLDRNGKAPVLFQIPGGAWTTGNKR
MAB_2814|M.abscessus_ATCC_1997      SPAEG-------------------------GVRPVFVLIHGGGWVIGDLD
                                                                  .  **:. : **.*  *   

Mflv_0436|M.gilvum_PYR-GCK          PQSYPLMSHLADHGWICVSIDYRVSPRNTWPDHIVDVKRALAWIKEHIAE
Mvan_0231|M.vanbaalenii_PYR-1       PQAYPLLSHLADHGWICVSIDYRVSPRNTWPDHIVDVKRALAWIKEHIAE
MSMEG_0302|M.smegmatis_MC2_155      PQSYPLMSHLAEQGWICVSIGYRISPKHSWPDHIVDVKQALAWVKANIAD
MMAR_3429|M.marinum_M               GQAHPLMSHLAELGWVCVAINYRHSPRNTWPDHIIDVKRALAWVKAHIAE
MUL_2704|M.ulcerans_Agy99           GQAHPLMSHLAELGWVCVAINYRHSPRNTWPDHIIDVKRALASVKAHIAE
MAV_2146|M.avium_104                GQAHPLMSHLAELGWICVAINYRHSPRNTWPDHIVDVKRALAWVKQHIAG
Mb2305|M.bovis_AF2122/97            GQAHPLMSHLAELGWICVAINYRHSPRNTWPDHIIDVKRALAWVKAHISE
Rv2284|M.tuberculosis_H37Rv         GQAHPLMSHLAELGWICVAINYRHSPRNTWPDHIIDVKRALAWVKAHISE
TH_3835|M.thermoresistible__bu      GQAHPLMSHLAELGWICVAINYRHSPRNTWPDHIIDVKRALAWVKEHIAD
MAB_2814|M.abscessus_ATCC_1997      THDAVARAAAVQADAVVVSVDYRLAPEHPYPAAVEDCWAALQWVHEHAAE
                                     :     :  .: . : *::.** :*.:.:*  : *   **  :: : : 

Mflv_0436|M.gilvum_PYR-GCK          YGGDPDFVAITGGSAGGHLSSLAALTADDPQFQPGFEDADTSVVAAVPVY
Mvan_0231|M.vanbaalenii_PYR-1       YGGDPDFVAITGGSAGGHLSALAALTADDPQFQPGFEDADTSVAAAVPIY
MSMEG_0302|M.smegmatis_MC2_155      FGGDPESVCITGGSAGGHLTALAALTPNDPKWQPGFEDADTSVVAAVPVY
MMAR_3429|M.marinum_M               YGGDPDFIAITGGSAGGHLSSLAALTPNDPQFQPGFEEADTRVQAAVPFY
MUL_2704|M.ulcerans_Agy99           YGGDPDFIAITGGSAGGHLSSLAALTPNDPQFQPGFEEADTRVQAAVPFY
MAV_2146|M.avium_104                YGGDPDFIAITGGSAGGHLSSLAALTPNDPKYQPGFEDADTRVQAAVPFY
Mb2305|M.bovis_AF2122/97            YGGDPDFIAITGGSAGGHLSSLAALTPNDPRFQPGFEEADTRVQAAVPFY
Rv2284|M.tuberculosis_H37Rv         YGGDPDFIAITGGSAGGHLSSLAALTPNDPRFQPGFEEADTRVQAAVPFY
TH_3835|M.thermoresistible__bu      YGGDPDFLAITGGSAGGHLSSLAALTPNDPRFQPGFEDADTRVQAAVPFY
MAB_2814|M.abscessus_ATCC_1997      IGGDPGRLAVGGDSAGGNLSAVMAQLARDNGIDLAFQVLWYPATTFDTTL
                                     ****  :.: *.****:*::: *  . *   : .*:     . :  .  

Mflv_0436|M.gilvum_PYR-GCK          GRYDWVSAQGSGRREFLAFLQKFVVKKPVTRNRQVYVDASPTHRLRADAP
Mvan_0231|M.vanbaalenii_PYR-1       GRYDWVSGRGSGRREFIAFLQEFVVKKPISGNRQLYVDASPRYRLRADAP
MSMEG_0302|M.smegmatis_MC2_155      GRYDWYSTTGPGRTEFMEILERLIVKRPLDGNAELYRDASPIMLVRPDAP
MMAR_3429|M.marinum_M               GVYDFTRFDDAMHPMMPGLLVRSVVKQRPSANLQPFITASPVNHVSADAP
MUL_2704|M.ulcerans_Agy99           GVYDFTRFDDAMHPMMPGLLVRSVVKQRPSANLQPFITASPVNHVSADAP
MAV_2146|M.avium_104                GIYDFTRFDDSLHPMMPGLLIKSIIKQRPSTHLETFAAASPITHVNPDAP
Mb2305|M.bovis_AF2122/97            GVYDFTRLQDAMHPMMLPLLERMVVKQPRTANMQSYLDASPVTHISADAP
Rv2284|M.tuberculosis_H37Rv         GVYDFTRLQDAMHPMMLPLLERMVVKQPRTANMQSYLDASPVTHISADAP
TH_3835|M.thermoresistible__bu      GVYDFTRFDDAMHPSMPELLERWVIKQPHSSNRETYASASPVNHISADAP
MAB_2814|M.abscessus_ATCC_1997      PSMVENAEAPVLDFKTVGALSKWYLGDTNPATAGPTLVPARAENFEGLAP
                                                       * .  :             .:    .   **

Mflv_0436|M.gilvum_PYR-GCK          PFFILHGQDDSIIPVPEGREFAEALKEVSTSPVVYAEIPYAQHAFDFYYG
Mvan_0231|M.vanbaalenii_PYR-1       PFFILHGRDDSIIPVPEGRAFAEALRNVSTSPVVYAEIPHAQHAFDFYYG
MSMEG_0302|M.smegmatis_MC2_155      PFFVLHGTNDSLIPVVEGRDFVAALREVSNSPVVYAEIPHAQHAFDFF-G
MMAR_3429|M.marinum_M               PFFVLHGRNDSLVPVEQARAFVTALQGVSTQPVAYAELPFTQHAFDIF-G
MUL_2704|M.ulcerans_Agy99           PFFVLHGRNDSLVPVEQARAFVTALQGVSTQPVAYAELPSTQHAFDIF-G
MAV_2146|M.avium_104                PFFVLHGRNDSLAYVEQARAFVERLRQVSTQPVVYAELPFTQHAFDIF-G
Mb2305|M.bovis_AF2122/97            PFFVLHGRNDSLVPVQQARGFVDQLRQVSKQPVVYAELPFTQHAFDLL-G
Rv2284|M.tuberculosis_H37Rv         PFFVLHGRNDSLVPVQQARGFVDQLRQVSKQPVVYAELPFTQHAFDLL-G
TH_3835|M.thermoresistible__bu      PFFVLHGRNDSLVPVEQGRDFVRRLREVSTQPVVYAELPLAQHAFDIF-G
MAB_2814|M.abscessus_ATCC_1997      -AFIGTAQFDPLR--DDGAKYAELLRDAG-VPVQLHNAPTLIHGYLGY--
                                      *:  .  *.:    :.  :.  *: ..  **   : *   *.:     

Mflv_0436|M.gilvum_PYR-GCK          SPRAHYTAQAIETFLSWVMATRRSESADRPTSPVRAS
Mvan_0231|M.vanbaalenii_PYR-1       SPRAHYTAQAVEEFLSWVQGER---MLARKAG-----
MSMEG_0302|M.smegmatis_MC2_155      SPHGHFTADAVEKFLNWVLAKR---GVAQNR------
MMAR_3429|M.marinum_M               SARAAHAAIAVEQFLAETYVRQQR-------------
MUL_2704|M.ulcerans_Agy99           SARAAHAAIAVEQFLAETYVRQQR-------------
MAV_2146|M.avium_104                SVRAAHTAVAVEQFLAEVYSARDRLPDQLIARSR---
Mb2305|M.bovis_AF2122/97            SARAAHTAIAVEQFLAEVYATQHAGSEPGPAVAIP--
Rv2284|M.tuberculosis_H37Rv         SARAAHTAIAVEQFLAEVYATQHAGSEPGPAVAIP--
TH_3835|M.thermoresistible__bu      SARAAHTAVAVEQFLAEIYANTVLGEGPRAQPAPR--
MAB_2814|M.abscessus_ATCC_1997      --ADIVPSATEERDLSLAALKQALHG-----------
                                          .: : *  *