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M. thermoresistible (build 8) TH_3828 (-)

annotation: acyl-CoA dehydrogenase domain protein
coordinates: 4229861 - 4231267
length: 469

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_3828 - - 100% (469) acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8) TH_2926 - 9e-42 31.54% (390) PUTATIVE acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8) TH_3140 - 7e-39 31.28% (374) PUTATIVE acyl-CoA dehydrogenase domain protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3163 fadE24 0.0 78.98% (471) acyl-CoA dehydrogenase FADE24
M. gilvum PYR-GCK Mflv_4455 - 0.0 77.54% (472) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv3139 fadE24 0.0 78.98% (471) acyl-CoA dehydrogenase FADE24
M. leprae Br4923 MLBr_00661 fadE24 0.0 75.21% (468) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_3486 - 0.0 69.36% (470) acyl-CoA dehydrogenase
M. marinum M MMAR_1510 fadE24 0.0 78.46% (469) acyl-CoA dehydrogenase FadE24
M. avium 104 MAV_4018 - 0.0 79.05% (463) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_2081 - 0.0 81.80% (445) putative acyl-CoA dehydrogenase
M. ulcerans Agy99 MUL_2431 fadE24 0.0 77.19% (469) acyl-CoA dehydrogenase FadE24
M. vanbaalenii PYR-1 Mvan_1907 - 0.0 77.71% (471) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3163|M.bovis_AF2122/97            MTNTTSAANAAKPSGARTDRRGRTTGVGLAPHKRTGIDVALALLTPIVGQ
Rv3139|M.tuberculosis_H37Rv         MTNTTSAANAAKPSGARTDRRGRTTGVGLAPHKRTGIDVALALLTPIVGQ
MLBr_00661|M.leprae_Br4923          MTDT---APSAKPSSVRLKRGGLRSGVGMQPHKRTGFDVAIAMLTPLVGQ
MAV_4018|M.avium_104                MTDS---GSTKTP--ARVKRRDRQSGVGLQPHKRTGIDIAIALLTPLVGQ
MMAR_1510|M.marinum_M               MTETLP-APSAKRSRSRDDR---QTSLGMQPHKRTGIDVALAFLTPIIGQ
MUL_2431|M.ulcerans_Agy99           MTETLP-APSAKRSRSRDDR---QTSLGMQPHKRTGIDVALAFLTPIIGQ
Mflv_4455|M.gilvum_PYR-GCK          MTNTLP-----------PKRGDRESAVGLQKHRRTAIDVGMALLTPLMGQ
Mvan_1907|M.vanbaalenii_PYR-1       MTNTLP-----------SKRGGRESAVGLQTHKRSVTDIGLALITPIVGQ
MSMEG_2081|M.smegmatis_MC2_155      --------------------------MGLQKHKRTATDIGLALITPIVGQ
TH_3828|M.thermoresistible__bu      MTNTLP---STNGSTPRRKRTGPESAVGLQRHKRTATDIGLALITPLVGQ
MAB_3486|M.abscessus_ATCC_1997      MTNTLT-PRDEKKAAKSKSLAKHETGVGLQKHKRGAIDILIAVLTPIAGS
                                                              :*:  *:*   *: :*.:**: *.

Mb3163|M.bovis_AF2122/97            EFLDKYRLRDPLNRSLRYGVKTMFATAGAATRQFQRVQGLRGG-PTRLKS
Rv3139|M.tuberculosis_H37Rv         EFLDKYRLRDPLNRSLRYGVKTMFATAGAATRQFQRVQGLRGG-PTRLKS
MLBr_00661|M.leprae_Br4923          DFLDKYHLRYPLNRALRYGVKATFSTAAATSRQFKRVQNLRGG-ATRLQP
MAV_4018|M.avium_104                EFLDKYHLRDPLNRGLRYGTKTIFSTGAATSRQFKRVQNLRGG-PTRLKS
MMAR_1510|M.marinum_M               EFLDKYNLRDPLNRGLRYGVKTMFSTSGKANRQFQRVQNLRGGGPVRLKS
MUL_2431|M.ulcerans_Agy99           EFLDKYTLRDPLNRGLRYGVKTMFSTSGKANRQFQRVQNLRGGGPVRLKS
Mflv_4455|M.gilvum_PYR-GCK          EFLDKYNLRDPLNRGLKYGVKHGFSAAGAATRQFKRVQGIGKP-ATRLTE
Mvan_1907|M.vanbaalenii_PYR-1       EFLDRYNLREPLNRGIRYGVKHAFSAAGASTRQFKRIQGLGKP-ATRLEA
MSMEG_2081|M.smegmatis_MC2_155      EWLDRYGLRDPLNRGLKYGVKQVFSTAGATTRQFKRIQGIGKA-PTRLKA
TH_3828|M.thermoresistible__bu      EFLDKYNLRDPLNRALRYGVKTAFSTAGAATRQFKRVQGLRGE-PTRLKP
MAB_3486|M.abscessus_ATCC_1997      ELLDKYNLRGAFNKGIFESTKGLFTTLGVANRTFKKVTGSKGG-PKRLDK
                                    : **:* ** .:*:.:  ..*  *:: . :.* *::: .     . **  

Mb3163|M.bovis_AF2122/97            S---GRDYFDLTPDDDQKLIIETVDEFAEEVLRPAAHDADDAATYPSDLT
Rv3139|M.tuberculosis_H37Rv         S---GRDYFDLTPDDDQKLIIETVDEFAEEVLRPAAHDADDAATYPSDLT
MLBr_00661|M.leprae_Br4923          S---GRNYFDLTPDDNQKLIVETIDEFSAEILRPAAHDADEAAAYPPDLI
MAV_4018|M.avium_104                S---GKDYFDLTPDDEQKMIVETLDEFAAEVLRPAAHDADEAATYPRDLI
MMAR_1510|M.marinum_M               S---GKDYFDLTPDDDQKMIVETVQEFAAEILRPAAHDADEAISYPADLI
MUL_2431|M.ulcerans_Agy99           S---GKDYFDLTPDDDQKMIVETVQEFAAEILRPAAHDADEAISYPADLI
Mflv_4455|M.gilvum_PYR-GCK          NRPKGSDYFDLTPDDDQKMIVQTVEEFAEEILRPAAHDADDAATYPPDLI
Mvan_1907|M.vanbaalenii_PYR-1       HRPQGSDYFDLTPDEDQKMIVETVEEFAEEILRPAAYDADDAASYPPDLI
MSMEG_2081|M.smegmatis_MC2_155      S---GADLFDLTPDDDQKMIVETVNEFAAEILRPAAEEADEAATYPPDLI
TH_3828|M.thermoresistible__bu      S---GSDYFDLTPDDEQQMIVDTVSEFAKEVLRPAAREADDAARFPADLM
MAB_3486|M.abscessus_ATCC_1997      A---NADYFDLNPEDEQKMIADTVKEFAVEVIRPAAYESDKNKTYPADLL
                                        . : ***.*:::*::* :*:.**: *::**** ::*.   :* ** 

Mb3163|M.bovis_AF2122/97            AKAAELGITAINIPEDFDGIAEHRSSVTNVLVAEALAYGDMGLALPILAP
Rv3139|M.tuberculosis_H37Rv         AKAAELGITAINIPEDFDGIAEHRSSVTNVLVAEALAYGDMGLALPILAP
MLBr_00661|M.leprae_Br4923          AKAAKLGITTINIPEYFDGIAERRSSVTNVLVAEALAYGDMGLTLPILAP
MAV_4018|M.avium_104                AKAAELGITAINIPEDFDGIAAHRSSVTNVLVAEALAYGDMGLALPLLAP
MMAR_1510|M.marinum_M               AKAAELGITAINIPEDFDGIAEQRSTVTNALVAEALAYGDMGLALPILAP
MUL_2431|M.ulcerans_Agy99           AKAAELGITAINIPEDFDGIAEQRSTVTNALVAEALAYGDMGLALSILAP
Mflv_4455|M.gilvum_PYR-GCK          AKAAELGITAINIPEDFDGIAEHRSTVTNALVAEALAYGDMGLALPILAP
Mvan_1907|M.vanbaalenii_PYR-1       AKAAELGITAINVPEDFDGIAEHRTTVTGALVAEALAYGDMGLALPILAP
MSMEG_2081|M.smegmatis_MC2_155      AKAAELGITAVNVPEDFEGIAEHRSTVTNALVAEALAYGDMGLALPILAP
TH_3828|M.thermoresistible__bu      GKAAELGITALNIPENFDGIAAHRSTVTSALVAEALAYGDMGLALPILAP
MAB_3486|M.abscessus_ATCC_1997      GKVAELGVTAINIPEDFDGIASQRSTVTNSLVAEALSYGDMGLALPILAP
                                    .*.*:**:*::*:** *:*** :*::**. ******:******:*.:***

Mb3163|M.bovis_AF2122/97            GGVASALTHWGSADQQATYLKEFAGENVPQACVAITEPQPLFDPTRLKTT
Rv3139|M.tuberculosis_H37Rv         GGVASALTHWGSADQQATYLKEFAGENVPQACVAITEPQPLFDPTRLKTT
MLBr_00661|M.leprae_Br4923          GGVAATLTYWGSADQQATYLKEFTGENVPQACVAIAEPQPLFDPTRLKTI
MAV_4018|M.avium_104                GGVASALTHWGSAEQQATYLPEFAGENVPQACVAIAEPQPLFDPTRLKTS
MMAR_1510|M.marinum_M               GGVASALTHWGSADQQATYLSEFAGENVPQACVAIAEPQPLFDPTRLKTT
MUL_2431|M.ulcerans_Agy99           GGVASALTHWGSADQQATYLSEFAGDNVPQACVAITEPQPLFDPTRLKTT
Mflv_4455|M.gilvum_PYR-GCK          GGVASALTHWGSADQQATYLREFAGESVPQACLAIAEPHPLFDPTALRTT
Mvan_1907|M.vanbaalenii_PYR-1       GGVASALTHWGSADQQATYLKEFSGDNVPQACVAIAEPHPLFDPTALKTT
MSMEG_2081|M.smegmatis_MC2_155      GGVASALTHWGSADQQATYLKEYAGDNVPQSSVVIAEPHALFDPTELKTT
TH_3828|M.thermoresistible__bu      GGVAAALTHWGSADQQATYLPEYAGENVPQSAVVIAEPQPLFDPTMLKTT
MAB_3486|M.abscessus_ATCC_1997      SGVASALTNWGSADQQATYLKEFAGENVPQASVVIAEPQALFDPFSLKTT
                                    .***::** ****:****** *::*:.***:.:.*:**:.****  *:* 

Mb3163|M.bovis_AF2122/97            AVRTPSGYRLDGVKSLIPAAADAELFIVGAQLGGKPALFIVESAASGLTV
Rv3139|M.tuberculosis_H37Rv         AVRTPSGYRLDGVKSLIPAAADAELFIVGAQLGGKPALFIVESAASGLTV
MLBr_00661|M.leprae_Br4923          AVRTPSGYRLDGVKSLVPAAASAELFIIGAQLNGKPALFIVESSTKGLTV
MAV_4018|M.avium_104                AVRTPSGYRLDGVKSLVPAAADAELFIVGAQLDGKPALFIVESSTKGLTV
MMAR_1510|M.marinum_M               AVRTPSGYRLDGVKSLVPAAADAELFIVAAQLDGKPALFIVESSAAGLTV
MUL_2431|M.ulcerans_Agy99           AVRTPSGYRLDGVKSLVPAAADAELFIVAAQLDGKPALFIVESSAAGLIV
Mflv_4455|M.gilvum_PYR-GCK          AVRTPSGYRLDGVKSLVPAAADAELFIIAAALGGKPALFLVEASTPGLTV
Mvan_1907|M.vanbaalenii_PYR-1       AVRTPSGYRLDGVKSLVPAAADAEVFIIAAQLNGKPALFIVEASTKGLTV
MSMEG_2081|M.smegmatis_MC2_155      AVRTPSGYRLSGVKSLVPAAADAELFIVAAQFNGKPALFIVEASSKGLSV
TH_3828|M.thermoresistible__bu      AVRTPSGYRLHGVKSLVPAAADAELFIVGAQLSGRPTLFIVESDTAGLSV
MAB_3486|M.abscessus_ATCC_1997      ATRTPSGFRLNGTKSLVPAAAQAELFIVAANYNGRPTLFIVESGTEGITV
                                    *.*****:** *.***:****.**:**:.*  .*:*:**:**: : *: *

Mb3163|M.bovis_AF2122/97            KADPSMGIRGAALGQVELCGVSVPLNARLGEDEASDND----YSEALALA
Rv3139|M.tuberculosis_H37Rv         KADPSMGIRGAALGQVELCGVSVPLNARLGEDEASDND----YSEALALA
MLBr_00661|M.leprae_Br4923          KADPSMGIRAAALGQVELCGVSAPLDARLGEDDATDND----YSEAIALA
MAV_4018|M.avium_104                KADPSMGIRAAELGHVELSGVTVPLGARLGEDEATDDD----YSEAIALS
MMAR_1510|M.marinum_M               KADPSMGIRAAALGQIELSKVSVPLSARLGEDQATDAD----YSEAIALA
MUL_2431|M.ulcerans_Agy99           KADPSMGIRAAALGQIELSKVSVPLRARLGEDQATDAD----YSEAIALA
Mflv_4455|M.gilvum_PYR-GCK          TADPSMGIRAAALGRVELAKVTVPLSARLGEEDASAADTAQIYSDAIALS
Mvan_1907|M.vanbaalenii_PYR-1       TPDPSMGIRAAALGRVELDKVTVPLSARLGEEDATDAD----YSEAIALS
MSMEG_2081|M.smegmatis_MC2_155      KADRSMGLRAAALGQIELDNVTVPLSARLGEDGATDQD----YSEAIALA
TH_3828|M.thermoresistible__bu      KADPSMGLRPAALGRLQLDNVTVPLSARLGEDVSEQEHDQN-YSEAVALA
MAB_3486|M.abscessus_ATCC_1997      EEDPSMGIRGAALGRLNLNNVAVPAANILGEEEGSDTALAN-YSEAVALA
                                      * ***:* * **:::*  *:.*    ***: .        **:*:**:

Mb3163|M.bovis_AF2122/97            RLGWAALAVGTSHAVLDYVVPYVKQRQAFGEPIAHRQAVAFMCANIAIEL
Rv3139|M.tuberculosis_H37Rv         RLGWAALAVGTSHAVLDYVVPYVKQRQAFGEPIAHRQAVAFMCANIAIEL
MLBr_00661|M.leprae_Br4923          RLGWAALAVGTSHAVLDYVMPYVKEREAFGEPIARRQAVAFMCANIAIEL
MAV_4018|M.avium_104                RLGWAALTVGTSHAVLDYVVPYVKEREAFGEPIARRQAVAFMCANIAIEL
MMAR_1510|M.marinum_M               RLGWAALAVGTSHAVLDYVIPYVKEREAFGEPIARRQAVAFMCANIAIEL
MUL_2431|M.ulcerans_Agy99           RLGWAALAVGTSHAVLDYVIPYVKERKAFGEPIARRQAVAFMCANIAIEL
Mflv_4455|M.gilvum_PYR-GCK          RLGWAALAVGTSHAVLDYVIPYVKEREAFGEPIARRQSVAFMCANIAIEL
Mvan_1907|M.vanbaalenii_PYR-1       RLGWAALAVGTSHAVLDYVIPYVKERTAFGEPIAHRQSVAFMCANIAIEL
MSMEG_2081|M.smegmatis_MC2_155      RLGWAALAVGTSHAVLDYVVPYVKERHAFGEPIAHRQSVAFMCANIAIEL
TH_3828|M.thermoresistible__bu      RLGWAALAVGTSHAVLDYVVPYVKERHAFGEPIAHRQAVAFMTADIAIEL
MAB_3486|M.abscessus_ATCC_1997      RLGWASLAVGTGQAVLDYVIPYVKQREAFGEPIARRQAVAFMCANIAIEL
                                    *****:*:***.:******:****:* *******:**:**** *:*****

Mb3163|M.bovis_AF2122/97            DGLRLITWRGASRAEQGLPFAREAALAKRLGSDKGMQIGLDGVQLLGGHG
Rv3139|M.tuberculosis_H37Rv         DGLRLITWRGASRAEQGLPFAREAALAKRLGSDKGMQIGLDGVQLLGGHG
MLBr_00661|M.leprae_Br4923          DGLRLITWRGASRAEQGLSFAREAALAKRLGSDKAMQIGLDGVQLLGGHG
MAV_4018|M.avium_104                DGLRLITWRGAARAEQGLPFAREAALAKRLGADKGMQIGSDGVQLLGGHG
MMAR_1510|M.marinum_M               DGLRLITWRGASRAEQGLPFAREAALAKRLGSDKGMQIGLDGVQLLGGHG
MUL_2431|M.ulcerans_Agy99           DGLRLITWRGASRAEQGLSFAREAALAKRLGSDKGMQIGLDGVQLLGGHG
Mflv_4455|M.gilvum_PYR-GCK          DGLRLITWRGASRAEQGLSFAREAALAKKLGADKGMQIGLDGVQLLGGHG
Mvan_1907|M.vanbaalenii_PYR-1       DGLRLITWRGAARADQGMSFAREAALAKKLGSDKAMQIGLDGVQLLGGHG
MSMEG_2081|M.smegmatis_MC2_155      DGLRLITWRGAARAEQGLPFAREAALARKLGADKGMQIGLDGVQLLGGHG
TH_3828|M.thermoresistible__bu      DGLRLITWRGASRAEQGMPFIREAALAKRFATDKGMRIGLDGVQLLGGHG
MAB_3486|M.abscessus_ATCC_1997      DGLRLVTLRGASRAEQGLPFVREAALARKLATDKGMQIGLDGVQLLGGHG
                                    *****:* ***:**:**:.* ******:::.:**.*:** **********

Mb3163|M.bovis_AF2122/97            YTKEHPVERWYRDLRAIGVAEGVVVI
Rv3139|M.tuberculosis_H37Rv         YTKEHPVERWYRDLRAIGVAEGVVVI
MLBr_00661|M.leprae_Br4923          FIKEHPVERWYRDLRAIGVAEGVVVI
MAV_4018|M.avium_104                YTNEHPVERWYRDLRAIGVAEGVVVI
MMAR_1510|M.marinum_M               YTKEHPVERWYRDLRAIGVAEGVVVI
MUL_2431|M.ulcerans_Agy99           YTKEHPVERWYRDLRAIGVAEGVVVI
Mflv_4455|M.gilvum_PYR-GCK          YTKEHPVERWYRDLRAIGVAEGVVVL
Mvan_1907|M.vanbaalenii_PYR-1       YTKEHPVERWYRDLRALGVAEGVVVL
MSMEG_2081|M.smegmatis_MC2_155      YTKEHPVERWYRDLRAIGIAEGVVVI
TH_3828|M.thermoresistible__bu      YTKEHPVERWYRDLRAIGVAEGVVVL
MAB_3486|M.abscessus_ATCC_1997      FTKEHPVERWYRNLRAIGVAEGVVVL
                                    : :*********:***:*:******:

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_3828	-	-	100% (469)	acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)	TH_2926	-	9e-42	31.54% (390)	PUTATIVE acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)	TH_3140	-	7e-39	31.28% (374)	PUTATIVE acyl-CoA dehydrogenase domain protein