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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3809 | - | - | 100% (365) | putative D-3-phosphoglycerate dehydrogenase |
| M. thermoresistible (build 8) | TH_2037 | serA | 1e-42 | 38.85% (260) | PROBABLE D-3-PHOSPHOGLYCERATE DEHYDROGENASE SERA1 (PGDH) |
| M. thermoresistible (build 8) | TH_3383 | - | 1e-37 | 39.00% (259) | PUTATIVE D-isomer specific 2-hydroxyacid dehydrogenase, |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3020c | serA1 | 1e-44 | 40.38% (260) | D-3-phosphoglycerate dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4234 | - | 4e-45 | 40.38% (260) | D-3-phosphoglycerate dehydrogenase |
| M. tuberculosis H37Rv | Rv2996c | serA1 | 1e-44 | 40.38% (260) | D-3-phosphoglycerate dehydrogenase |
| M. leprae Br4923 | MLBr_01692 | serA | 3e-43 | 38.85% (260) | D-3-phosphoglycerate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3304c | - | 2e-45 | 41.60% (250) | D-3-phosphoglycerate dehydrogenase |
| M. marinum M | MMAR_1715 | serA1 | 7e-45 | 40.38% (260) | D-3-phosphoglycerate dehydrogenase SerA1 |
| M. avium 104 | MAV_3847 | serA | 8e-44 | 40.00% (260) | D-3-phosphoglycerate dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2378 | serA | 1e-43 | 38.85% (260) | D-3-phosphoglycerate dehydrogenase |
| M. ulcerans Agy99 | MUL_1952 | serA1 | 8e-45 | 40.38% (260) | D-3-phosphoglycerate dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_2128 | - | 1e-45 | 40.77% (260) | D-3-phosphoglycerate dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3020c|M.bovis_AF2122/97 ---MSLPVVLIADKLAPSTVAALG--DQVEVRWVDGPDRDKLLAAVPEAD
Rv2996c|M.tuberculosis_H37Rv ---MSLPVVLIADKLAPSTVAALG--DQVEVRWVDGPDRDKLLAAVPEAD
MLBr_01692|M.leprae_Br4923 ---MDLPVVLIADKLAQSTVAALG--DQVEVRWVDGPDRTKLLAAVPEAD
MAV_3847|M.avium_104 ---MNLPVVLIADKLAESTVAALG--DQVEVRWVDGPDREKLLAAVPEAD
MMAR_1715|M.marinum_M ---MNLPVVLIADKLAQSTVAALG--DQVEVRWVDGPDREKLLAAVPEAD
MUL_1952|M.ulcerans_Agy99 ---MNLPVVLIADKLAQSTVAALG--DQVEVRWVDGPDREKLLAAVPEAD
MSMEG_2378|M.smegmatis_MC2_155 ---MSLPVVLIADKLAESTVAALG--DEVEVRWVDGPDRAKLLAAVPEAD
Mflv_4234|M.gilvum_PYR-GCK ---MSLPVVLIADKLAQSTVEALG--DQVEVRWVDGPDREKLLAAVADAD
Mvan_2128|M.vanbaalenii_PYR-1 ---MSLPVVLIADKLAQSTVEALG--DQVEVRWVDGPDREKLLAAVADAD
MAB_3304c|M.abscessus_ATCC_199 --------MLIADKLAPSTVEALG--DGVEVRWVDGPDRPALLAAVPEAD
TH_3809|M.thermoresistible__bu VSGISRPRLVFERWTDPAAGELLGAADIELVRLDLTADPADGWAALESAH
::: :: ** * ** .* **: .*.
Mb3020c|M.bovis_AF2122/97 ALLVRSATTVD-----------AEVLAAAPKLKIVARAGVGLDNVDVDAA
Rv2996c|M.tuberculosis_H37Rv ALLVRSATTVD-----------AEVLAAAPKLKIVARAGVGLDNVDVDAA
MLBr_01692|M.leprae_Br4923 ALLVRSATTVD-----------AEVLAAAPKLKIVARAGVGLDNVDVDAA
MAV_3847|M.avium_104 ALLVRSATTVD-----------AEVLAAAPKLKIVARAGVGLDNVDVDAA
MMAR_1715|M.marinum_M ALLVRSATTVD-----------AEVLAAATKLKIVARAGVGLDNVDVDAA
MUL_1952|M.ulcerans_Agy99 ALLVRSATTVD-----------AEVLAAATKLKIVARAGVGLDNVDVDAA
MSMEG_2378|M.smegmatis_MC2_155 ALLVRSATTVD-----------AEVIAAAPKLKIVARAGVGLDNVDVDAA
Mflv_4234|M.gilvum_PYR-GCK ALLVRSATTVD-----------AEVLAAAPKLKIVARAGVGLDNVDVDAA
Mvan_2128|M.vanbaalenii_PYR-1 ALLVRSATTVD-----------AEVLAAAPKLKIVARAGVGLDNVDVDAA
MAB_3304c|M.abscessus_ATCC_199 ALLVRSATTVD-----------AEVLAAGTKLKIVARAGVGLDNVDVKAA
TH_3809|M.thermoresistible__bu GYQVATRTDVASMADGGQWLADRNLVRRCGLLLAVCSAGAGYDVIDVDAC
. * : * * ::: * *. **.* * :**.*.
Mb3020c|M.bovis_AF2122/97 TARGVLVVNAPTSNIHSAAEHALALLLAASRQIPAADASLRE-HTWKRSS
Rv2996c|M.tuberculosis_H37Rv TARGVLVVNAPTSNIHSAAEHALALLLAASRQIPAADASLRE-HTWKRSS
MLBr_01692|M.leprae_Br4923 TARGVLVVNAPTSNIHSAAEHALALLLAASRQIAEADASLRA-HIWKRSS
MAV_3847|M.avium_104 TERGVLVVNAPTSNIHSAAEHALALLLAAAREIPAADASLRE-HTWKRSS
MMAR_1715|M.marinum_M TTRGVLVVNAPTSNIHSAAEHAMALLLAAARQIPAADASLRE-HTWKRSS
MUL_1952|M.ulcerans_Agy99 TTRGVLVVNAPTSNIHSAAEHAMALLLAAARQIPAADASLRE-HTWKRSS
MSMEG_2378|M.smegmatis_MC2_155 TARGVLVVNAPTSNIHSAAEHAIALLLATARQIPAADATLRE-RSWKRSS
Mflv_4234|M.gilvum_PYR-GCK TARGVLVVNAPTSNIHSAAEHALALLLSTARQIPAADATLRE-HTWKRSA
Mvan_2128|M.vanbaalenii_PYR-1 TARGVLVVNAPTSNIHSAAEHALALLLAAARQIPAADATLRE-HSWKRSS
MAB_3304c|M.abscessus_ATCC_199 TARGVLVVNAPTSNIHSAAEHAVTLLLATARQIPAADASLKA-HTWKRSS
TH_3809|M.thermoresistible__bu TEAGIAVCNNSGPGAEAVAEHALGLMLDLAKRITVADRMLRRGDLGDRLV
* *: * * . .. .:.****: *:* ::.*. ** *: .*
Mb3020c|M.bovis_AF2122/97 FSGTEIFGKTVGVVGLGRIGQLVAQRIAAFGAYVVAYDPYVSPARAAQLG
Rv2996c|M.tuberculosis_H37Rv FSGTEIFGKTVGVVGLGRIGQLVAQRIAAFGAYVVAYDPYVSPARAAQLG
MLBr_01692|M.leprae_Br4923 FSGTEIFGKTVGVVGLGRIGQLVAARIAAFGAHVIAYDPYVAPARAAQLG
MAV_3847|M.avium_104 FSGTEIFGKTVGVVGLGRIGQLVAQRLSAFGTHLIAYDPYVSPARAAQLG
MMAR_1715|M.marinum_M FSGAEIFGKTVGVVGLGRIGQLVAQRVEAFGAHVVAYDPYVSPARAAQLG
MUL_1952|M.ulcerans_Agy99 FSGAEIFGKTVGVVGLGRIGQLVAQRVEAFGAHVVAYDPYVSPARAAQLG
MSMEG_2378|M.smegmatis_MC2_155 FSGTEIFGKTVGVVGLGRIGQLVAQRLAAFGAHIVAYDPYVSQARAAQLG
Mflv_4234|M.gilvum_PYR-GCK FSGTEIFGKTVGVVGLGRIGQLVAQRLAAFGAHITAYDPYVSHARAAQLG
Mvan_2128|M.vanbaalenii_PYR-1 FSGTEIFGKTVGVVGLGRIGQLVAQRLAAFGAHITAYDPYVSHARAAQLG
MAB_3304c|M.abscessus_ATCC_199 FNGTEIFGKTVGVVGLGRIGQLFAQRLAAFGTHIVAYDPYVSAARAAQLG
TH_3809|M.thermoresistible__bu LRGSQLQHKTMGIVGLGAIGRRLVQLVAPFGMKVLAFDPYVDEKTAEALG
: *::: **:*:**** **: .. : .** : *:**** * **
Mb3020c|M.bovis_AF2122/97 IELLSLDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARG
Rv2996c|M.tuberculosis_H37Rv IELLSLDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARG
MLBr_01692|M.leprae_Br4923 IELMSFDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARG
MAV_3847|M.avium_104 IELLSLDELLARADFISVHLPKTPETAGLIDKDALAKTKPGVIIVNAARG
MMAR_1715|M.marinum_M IELLPLDDLLARADFISVHLPKTPETAGLLGKEALAKTKPGVIIVNAARG
MUL_1952|M.ulcerans_Agy99 IELLPLDDLLARADFISVHLPKTPETAGLLGKEALAKTKPGVIIVNAARG
MSMEG_2378|M.smegmatis_MC2_155 IELLPLDDLLARADFISVHLPKTKETAGLLGKEALAKTKKGVIIVNAARG
Mflv_4234|M.gilvum_PYR-GCK IELLTLDELLSRADFISVHLPKTKETAGLIGTEALAKTKPGVIIVNAARG
Mvan_2128|M.vanbaalenii_PYR-1 IELLTLDELLGRADFISVHLPKTKETAGLIGKEALAKTKPGVIIVNAARG
MAB_3304c|M.abscessus_ATCC_199 IELLTLDELLGRADFISVHLPKTPETAGLIGKEALAKTKPGVIIVNAARG
TH_3809|M.thermoresistible__bu ARSVSLEELLGCSDFVQLTCPLTAETEGLIGRAQFAAMKPTAFFVTTARG
. :.:::**. :**:.: * * ** **:. :* * .::*.:***
Mb3020c|M.bovis_AF2122/97 GLVDEAALADAITGGHVRAAGLDVFATEP-CTDSPLFELAQVVVTPHLGA
Rv2996c|M.tuberculosis_H37Rv GLVDEAALADAITGGHVRAAGLDVFATEP-CTDSPLFELAQVVVTPHLGA
MLBr_01692|M.leprae_Br4923 GLVDEVALADAVRSGHVRAAGLDVFATEP-CTDSPLFELSQVVVTPHLGA
MAV_3847|M.avium_104 GLVDEAALADAVRSGHVRAAGLDVFSKEP-CTDSPLFELPQVVVTPHLGA
MMAR_1715|M.marinum_M GLIDESALAEAITSGHVRGAGLDVFATEP-CTDSPLFELPQVVVTPHLGA
MUL_1952|M.ulcerans_Agy99 GLIDESALAEAITSGYVRGAGLDVFATEP-CTDSPLFELPQVVVTPHLGA
MSMEG_2378|M.smegmatis_MC2_155 GLIDEQALADAITSGHVRGAGLDVYATEP-CTDSPLFDLPQVVVTPHLGA
Mflv_4234|M.gilvum_PYR-GCK GLIDEQALADAITSGHVRGAGLDVFSTEP-CTDSPLFELPQVVVTPHLGA
Mvan_2128|M.vanbaalenii_PYR-1 GLIDEAALADAINSGHVRGAGLDVFSTEP-CTDSPLFELPQVVVTPHLGA
MAB_3304c|M.abscessus_ATCC_199 GLIDEAALADAIRSGHVRGAGLDVFSTEP-CTDSPLFELDQVVVTPHLGA
TH_3809|M.thermoresistible__bu RVHDEAALYEALTCGEIAGAGLDVFHDEPPRADHPLLTLDNVVATPHIAG
: ** ** :*: * : .*****: ** :* **: * :**.***:..
Mb3020c|M.bovis_AF2122/97 STAEAQDRAGTDVAESVRLALAGEFVPDAVNVGGGVVNEEVAPWLDLVRK
Rv2996c|M.tuberculosis_H37Rv STAEAQDRAGTDVAESVRLALAGEFVPDAVNVGGGVVNEEVAPWLDLVRK
MLBr_01692|M.leprae_Br4923 STAEAQDRAGTDVAESVRLALAGEFVPDAVNVDGGVVNEEVAPWLDLVCK
MAV_3847|M.avium_104 STTEAQDRAGTDVAASVKLALAGEFVPDAVNVAGGTVNEEVAPWLDLVRK
MMAR_1715|M.marinum_M STAEAQDRAGTDVAASVKLALAGEFVPDAVNIAGGAVNEEVAPWLDLACK
MUL_1952|M.ulcerans_Agy99 STAEAQDRAGTDVAASVKLALAGEFVPDAVNIAGGAVNEEVAPWLDLACK
MSMEG_2378|M.smegmatis_MC2_155 STAEAQDRAGTDVAASVKLALAGEFVPDAVNVGGGVVGEEVAPWLELVRK
Mflv_4234|M.gilvum_PYR-GCK STVEAQDRAGTDVAASVKLALAGEFVPDAVNVGGGAVGEEVAPWLDLVRK
Mvan_2128|M.vanbaalenii_PYR-1 STVEAQDRAGTDVAASVKLALAGEFVPDAVNVGGGAVGEEVAPWLDLVRK
MAB_3304c|M.abscessus_ATCC_199 STSEAQDRAGTDVAASVQLALAGEFVPDAVNVGGGVVSEEVAPWLEVVRK
TH_3809|M.thermoresistible__bu ITAEAARDIAVATADQWQTIFAGGVPPRLLNP---------EVWPRYSAR
* ** .. .* . : :** . * :* * :
Mb3020c|M.bovis_AF2122/97 LGVLAGVLSDELPVSLSVQVRGELAAEEVEVLRLSALRGLFSAVIEDAVT
Rv2996c|M.tuberculosis_H37Rv LGVLAGVLSDELPVSLSVQVRGELAAEEVEVLRLSALRGLFSAVIEDAVT
MLBr_01692|M.leprae_Br4923 LGVLVAALSDELPASLSVHVRGELASEDVEILRLSALRGLFSTVIEDAVT
MAV_3847|M.avium_104 LGLLAATLSDGPPVSLSVQVRGELASEDVEVLKLSALRGLFSAVVEGPVT
MMAR_1715|M.marinum_M LGVLAAALSDEPPVSLSVQARGELASEDVEVLKLSALRGLFSAVVEGPVT
MUL_1952|M.ulcerans_Agy99 LGVLAAALSDEPPVSLSVQAGGELASEDVEVLKLSALRGLFSAVVEGPVT
MSMEG_2378|M.smegmatis_MC2_155 LGLLVGALADAPPVSLQVQVRGELASEDVEILKLSALRGLFSAVVDEQVT
Mflv_4234|M.gilvum_PYR-GCK LGLLVGALSAELPTNLCVQVRGELASEEVEVLRLSALRGLFSAVIEDQVT
Mvan_2128|M.vanbaalenii_PYR-1 LGLLVGVLSSEPPVSLQVQVQGELASEEVEVLKLSALRGLFSAVIEHPVT
MAB_3304c|M.abscessus_ATCC_199 LGVLIGAVSEQLPTSLSVDVRGELASEDVAVLKLSALRGLFSSVIEDQVT
TH_3809|M.thermoresistible__bu FAEIFGFAPEPVSRTREREAVGR---------------------------
:. : . . . . .. *.
Mb3020c|M.bovis_AF2122/97 FVNAPALAAERGVTAEICKASESPNHRSVVDVRAVGADGSVVTVSGTLYG
Rv2996c|M.tuberculosis_H37Rv FVNAPALAAERGVTAEICKASESPNHRSVVDVRAVGADGSVVTVSGTLYG
MLBr_01692|M.leprae_Br4923 FVNAPALAAERGVSAEITTGSESPNHRSVVDVRAVASDGSVVNIAGTLSG
MAV_3847|M.avium_104 FVNAPALAEERGVTAEISTASESPNHRSVVDVRAVSHDGTVVNVAGTLSG
MMAR_1715|M.marinum_M FVNAPALAAERGVSVEISKASESPNHRSVVDVRVVGADGSVVSVSGTLYG
MUL_1952|M.ulcerans_Agy99 FVNAPALAAERGVSVEISKASESPNHRSVVDVRVVGADGSVVSVSGTLYG
MSMEG_2378|M.smegmatis_MC2_155 FVNAPALAADRGVTAEISTATESPNHRSVVDVRAVHADGSSINVAGTLSG
Mflv_4234|M.gilvum_PYR-GCK FVNAPALATERGVEASIDTESESPNHRSVVDVRAVAADGSTVNVSGTLTG
Mvan_2128|M.vanbaalenii_PYR-1 FVNAPALASERGVEASITTATESANHRSVVDVRAVAADGSTVNVAGTLTG
MAB_3304c|M.abscessus_ATCC_199 FVNAPSIAEERGVSAEITTATESPNHRSVVDVRAVYADGSVINVAGTLSG
TH_3809|M.thermoresistible__bu --------------------------------------------------
Mb3020c|M.bovis_AF2122/97 PQLSQKIVQINGRHFDLRAQGINLIIHYVDRPGALGKIGTLLGTAGVNIQ
Rv2996c|M.tuberculosis_H37Rv PQLSQKIVQINGRHFDLRAQGINLIIHYVDRPGALGKIGTLLGTAGVNIQ
MLBr_01692|M.leprae_Br4923 PQLVQKIVQVNGRNFDLRAQGMNLVIRYVDQPGALGKIGTLLGAAGVNIQ
MAV_3847|M.avium_104 PQLVEKIVQINGRNFDLRARGINLVINYVDQPGALGKIGTLLGSAGVNIQ
MMAR_1715|M.marinum_M AQLTHKIVQINGRHFDLRAEGTNLIVNYVDQPGALGKIGTLLGAAGVNIH
MUL_1952|M.ulcerans_Agy99 AQLTHKIVQINGRHFDLRAEGTNLIVNYVDQPGALGKIGTLLGAAGVNIH
MSMEG_2378|M.smegmatis_MC2_155 PQLVEKIVQINGRNFDLRAEGHNLIVNYSDKPGALGKIGTLLGGANVNIL
Mflv_4234|M.gilvum_PYR-GCK PQLVEKIVQINGRNLDLRAEGVNVIINYHDQPGALGKIGTLLGGANVNIL
Mvan_2128|M.vanbaalenii_PYR-1 PQLVEKIVQINGRNLELRAEGVNLIINYDDQPGALGKIGTLLGGAAVNIL
MAB_3304c|M.abscessus_ATCC_199 PQLVQKIVQINGRNFDLRAEGVNLVINYADVPGALGKIGTVLGGAEVNIQ
TH_3809|M.thermoresistible__bu --------------------------------------------------
Mb3020c|M.bovis_AF2122/97 AAQLSEDAEGPGATILLRLDQDVPDDVRTAIAAAVDAYKLEVVDLS
Rv2996c|M.tuberculosis_H37Rv AAQLSEDAEGPGATILLRLDQDVPDDVRTAIAAAVDAYKLEVVDLS
MLBr_01692|M.leprae_Br4923 AAQLSEDTEGPGATILLRLDQDVPGDVRSAIVAAVSANKLEVVNLS
MAV_3847|M.avium_104 AAQLSEDAEGPGATILLRLDQDVPADVRSAIGAAVGANKLEVVDLS
MMAR_1715|M.marinum_M AAQLSEDVEGPGATVLLRLDQDVPEDVRSAIAAAVGANRLEVVDLS
MUL_1952|M.ulcerans_Agy99 AAQLSEDVEGPGATVLLRLDQDVPEDVRSAIAAAVGANRLEVVDLS
MSMEG_2378|M.smegmatis_MC2_155 AAQLSQDASGDHATVMLRVDTDVPDDVRAAIADAVGASTLEVVDLS
Mflv_4234|M.gilvum_PYR-GCK AAQLSQDADGEGATIMLRVDREVPADVLAGIGRDVNALTLEVVDLT
Mvan_2128|M.vanbaalenii_PYR-1 AAQLSQDADGIGATVMLRLDREVPGEVLAAIGRDVNAVTLEVVDLT
MAB_3304c|M.abscessus_ATCC_199 AAQLSQDASGAAATIILRIDRTAPDAVLDEIRAAVGATTLELVDLS
TH_3809|M.thermoresistible__bu ----------------------------------------------