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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_2037 | serA | - | 100% (529) | PROBABLE D-3-PHOSPHOGLYCERATE DEHYDROGENASE SERA1 (PGDH) |
M. thermoresistible (build 8) | TH_3809 | - | 2e-42 | 38.85% (260) | PUTATIVE putative D-3-phosphoglycerate dehydrogenase |
M. thermoresistible (build 8) | TH_3383 | - | 2e-41 | 34.92% (295) | PUTATIVE D-isomer specific 2-hydroxyacid dehydrogenase, |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3020c | serA1 | 0.0 | 80.11% (528) | D-3-phosphoglycerate dehydrogenase |
M. gilvum PYR-GCK | Mflv_4234 | - | 0.0 | 82.39% (528) | D-3-phosphoglycerate dehydrogenase |
M. tuberculosis H37Rv | Rv2996c | serA1 | 0.0 | 80.11% (528) | D-3-phosphoglycerate dehydrogenase |
M. leprae Br4923 | MLBr_01692 | serA | 0.0 | 79.55% (528) | D-3-phosphoglycerate dehydrogenase |
M. abscessus ATCC 19977 | MAB_3304c | - | 0.0 | 78.78% (523) | D-3-phosphoglycerate dehydrogenase |
M. marinum M | MMAR_1715 | serA1 | 0.0 | 79.73% (528) | D-3-phosphoglycerate dehydrogenase SerA1 |
M. avium 104 | MAV_3847 | serA | 0.0 | 83.52% (528) | D-3-phosphoglycerate dehydrogenase |
M. smegmatis MC2 155 | MSMEG_2378 | serA | 0.0 | 82.95% (528) | D-3-phosphoglycerate dehydrogenase |
M. ulcerans Agy99 | MUL_1952 | serA1 | 0.0 | 79.73% (528) | D-3-phosphoglycerate dehydrogenase |
M. vanbaalenii PYR-1 | Mvan_2128 | - | 0.0 | 82.01% (528) | D-3-phosphoglycerate dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_4234|M.gilvum_PYR-GCK MSLPVVLIADKLAQSTVEALGDQVEVRWVDGPDREKLLAAVADADALLVR Mvan_2128|M.vanbaalenii_PYR-1 MSLPVVLIADKLAQSTVEALGDQVEVRWVDGPDREKLLAAVADADALLVR MAB_3304c|M.abscessus_ATCC_199 -----MLIADKLAPSTVEALGDGVEVRWVDGPDRPALLAAVPEADALLVR MSMEG_2378|M.smegmatis_MC2_155 MSLPVVLIADKLAESTVAALGDEVEVRWVDGPDRAKLLAAVPEADALLVR Mb3020c|M.bovis_AF2122/97 MSLPVVLIADKLAPSTVAALGDQVEVRWVDGPDRDKLLAAVPEADALLVR Rv2996c|M.tuberculosis_H37Rv MSLPVVLIADKLAPSTVAALGDQVEVRWVDGPDRDKLLAAVPEADALLVR MLBr_01692|M.leprae_Br4923 MDLPVVLIADKLAQSTVAALGDQVEVRWVDGPDRTKLLAAVPEADALLVR MMAR_1715|M.marinum_M MNLPVVLIADKLAQSTVAALGDQVEVRWVDGPDREKLLAAVPEADALLVR MUL_1952|M.ulcerans_Agy99 MNLPVVLIADKLAQSTVAALGDQVEVRWVDGPDREKLLAAVPEADALLVR MAV_3847|M.avium_104 MNLPVVLIADKLAESTVAALGDQVEVRWVDGPDREKLLAAVPEADALLVR TH_2037|M.thermoresistible__bu VSLPVVLIADKLAESTVAALGDQVEVRWVDGPDREKLLAAVADADALLVR :******* *** **** *********** *****.:******* Mflv_4234|M.gilvum_PYR-GCK SATTVDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIH Mvan_2128|M.vanbaalenii_PYR-1 SATTVDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIH MAB_3304c|M.abscessus_ATCC_199 SATTVDAEVLAAGTKLKIVARAGVGLDNVDVKAATARGVLVVNAPTSNIH MSMEG_2378|M.smegmatis_MC2_155 SATTVDAEVIAAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIH Mb3020c|M.bovis_AF2122/97 SATTVDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIH Rv2996c|M.tuberculosis_H37Rv SATTVDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIH MLBr_01692|M.leprae_Br4923 SATTVDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIH MMAR_1715|M.marinum_M SATTVDAEVLAAATKLKIVARAGVGLDNVDVDAATTRGVLVVNAPTSNIH MUL_1952|M.ulcerans_Agy99 SATTVDAEVLAAATKLKIVARAGVGLDNVDVDAATTRGVLVVNAPTSNIH MAV_3847|M.avium_104 SATTVDAEVLAAAPKLKIVARAGVGLDNVDVDAATERGVLVVNAPTSNIH TH_2037|M.thermoresistible__bu SATTVDAEVLAAAPKLKIVARAGVGLDNVDVEAATARGVLVVNAPTSNIH *********:**..*****************.*** ************** Mflv_4234|M.gilvum_PYR-GCK SAAEHALALLLSTARQIPAADATLREHTWKRSAFSGTEIFGKTVGVVGLG Mvan_2128|M.vanbaalenii_PYR-1 SAAEHALALLLAAARQIPAADATLREHSWKRSSFSGTEIFGKTVGVVGLG MAB_3304c|M.abscessus_ATCC_199 SAAEHAVTLLLATARQIPAADASLKAHTWKRSSFNGTEIFGKTVGVVGLG MSMEG_2378|M.smegmatis_MC2_155 SAAEHAIALLLATARQIPAADATLRERSWKRSSFSGTEIFGKTVGVVGLG Mb3020c|M.bovis_AF2122/97 SAAEHALALLLAASRQIPAADASLREHTWKRSSFSGTEIFGKTVGVVGLG Rv2996c|M.tuberculosis_H37Rv SAAEHALALLLAASRQIPAADASLREHTWKRSSFSGTEIFGKTVGVVGLG MLBr_01692|M.leprae_Br4923 SAAEHALALLLAASRQIAEADASLRAHIWKRSSFSGTEIFGKTVGVVGLG MMAR_1715|M.marinum_M SAAEHAMALLLAAARQIPAADASLREHTWKRSSFSGAEIFGKTVGVVGLG MUL_1952|M.ulcerans_Agy99 SAAEHAMALLLAAARQIPAADASLREHTWKRSSFSGAEIFGKTVGVVGLG MAV_3847|M.avium_104 SAAEHALALLLAAAREIPAADASLREHTWKRSSFSGTEIFGKTVGVVGLG TH_2037|M.thermoresistible__bu SAAEHAIALLLAAARQIPAADATLRQRTWKRSEFSGVEIYDKTVGVVGLG ******::***:::*:*. ***:*: : **** *.*.**:.********* Mflv_4234|M.gilvum_PYR-GCK RIGQLVAQRLAAFGAHITAYDPYVSHARAAQLGIELLTLDELLSRADFIS Mvan_2128|M.vanbaalenii_PYR-1 RIGQLVAQRLAAFGAHITAYDPYVSHARAAQLGIELLTLDELLGRADFIS MAB_3304c|M.abscessus_ATCC_199 RIGQLFAQRLAAFGTHIVAYDPYVSAARAAQLGIELLTLDELLGRADFIS MSMEG_2378|M.smegmatis_MC2_155 RIGQLVAQRLAAFGAHIVAYDPYVSQARAAQLGIELLPLDDLLARADFIS Mb3020c|M.bovis_AF2122/97 RIGQLVAQRIAAFGAYVVAYDPYVSPARAAQLGIELLSLDDLLARADFIS Rv2996c|M.tuberculosis_H37Rv RIGQLVAQRIAAFGAYVVAYDPYVSPARAAQLGIELLSLDDLLARADFIS MLBr_01692|M.leprae_Br4923 RIGQLVAARIAAFGAHVIAYDPYVAPARAAQLGIELMSFDDLLARADFIS MMAR_1715|M.marinum_M RIGQLVAQRVEAFGAHVVAYDPYVSPARAAQLGIELLPLDDLLARADFIS MUL_1952|M.ulcerans_Agy99 RIGQLVAQRVEAFGAHVVAYDPYVSPARAAQLGIELLPLDDLLARADFIS MAV_3847|M.avium_104 RIGQLVAQRLSAFGTHLIAYDPYVSPARAAQLGIELLSLDELLARADFIS TH_2037|M.thermoresistible__bu RIGQLVAQRLAAFGTHLIAYDPYVSPARAAQLGIELVDLDELLGRADIIS *****.* *: ***::: ******: **********: :*:**.***:** Mflv_4234|M.gilvum_PYR-GCK VHLPKTKETAGLIGTEALAKTKPGVIIVNAARGGLIDEQALADAITSGHV Mvan_2128|M.vanbaalenii_PYR-1 VHLPKTKETAGLIGKEALAKTKPGVIIVNAARGGLIDEAALADAINSGHV MAB_3304c|M.abscessus_ATCC_199 VHLPKTPETAGLIGKEALAKTKPGVIIVNAARGGLIDEAALADAIRSGHV MSMEG_2378|M.smegmatis_MC2_155 VHLPKTKETAGLLGKEALAKTKKGVIIVNAARGGLIDEQALADAITSGHV Mb3020c|M.bovis_AF2122/97 VHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHV Rv2996c|M.tuberculosis_H37Rv VHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHV MLBr_01692|M.leprae_Br4923 VHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEVALADAVRSGHV MMAR_1715|M.marinum_M VHLPKTPETAGLLGKEALAKTKPGVIIVNAARGGLIDESALAEAITSGHV MUL_1952|M.ulcerans_Agy99 VHLPKTPETAGLLGKEALAKTKPGVIIVNAARGGLIDESALAEAITSGYV MAV_3847|M.avium_104 VHLPKTPETAGLIDKDALAKTKPGVIIVNAARGGLVDEAALADAVRSGHV TH_2037|M.thermoresistible__bu VHLPKTPETAGLIGADALAKVKPGVIIVNAARGGLIDEQALADAIISGRV ****** *****:. :****.* ************:** ***:*: .* * Mflv_4234|M.gilvum_PYR-GCK RGAGLDVFSTEPCTDSPLFELPQVVVTPHLGASTVEAQDRAGTDVAASVK Mvan_2128|M.vanbaalenii_PYR-1 RGAGLDVFSTEPCTDSPLFELPQVVVTPHLGASTVEAQDRAGTDVAASVK MAB_3304c|M.abscessus_ATCC_199 RGAGLDVFSTEPCTDSPLFELDQVVVTPHLGASTSEAQDRAGTDVAASVQ MSMEG_2378|M.smegmatis_MC2_155 RGAGLDVYATEPCTDSPLFDLPQVVVTPHLGASTAEAQDRAGTDVAASVK Mb3020c|M.bovis_AF2122/97 RAAGLDVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVR Rv2996c|M.tuberculosis_H37Rv RAAGLDVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVR MLBr_01692|M.leprae_Br4923 RAAGLDVFATEPCTDSPLFELSQVVVTPHLGASTAEAQDRAGTDVAESVR MMAR_1715|M.marinum_M RGAGLDVFATEPCTDSPLFELPQVVVTPHLGASTAEAQDRAGTDVAASVK MUL_1952|M.ulcerans_Agy99 RGAGLDVFATEPCTDSPLFELPQVVVTPHLGASTAEAQDRAGTDVAASVK MAV_3847|M.avium_104 RAAGLDVFSKEPCTDSPLFELPQVVVTPHLGASTTEAQDRAGTDVAASVK TH_2037|M.thermoresistible__bu RAAGIDVFAKEPCTDSPLFDLPQVVVTPHLGASTVEAQDRAGTDVAASVK *.**:**::.*********:* ************ *********** **: Mflv_4234|M.gilvum_PYR-GCK LALAGEFVPDAVNVGGGAVGEEVAPWLDLVRKLGLLVGALSAELPTNLCV Mvan_2128|M.vanbaalenii_PYR-1 LALAGEFVPDAVNVGGGAVGEEVAPWLDLVRKLGLLVGVLSSEPPVSLQV MAB_3304c|M.abscessus_ATCC_199 LALAGEFVPDAVNVGGGVVSEEVAPWLEVVRKLGVLIGAVSEQLPTSLSV MSMEG_2378|M.smegmatis_MC2_155 LALAGEFVPDAVNVGGGVVGEEVAPWLELVRKLGLLVGALADAPPVSLQV Mb3020c|M.bovis_AF2122/97 LALAGEFVPDAVNVGGGVVNEEVAPWLDLVRKLGVLAGVLSDELPVSLSV Rv2996c|M.tuberculosis_H37Rv LALAGEFVPDAVNVGGGVVNEEVAPWLDLVRKLGVLAGVLSDELPVSLSV MLBr_01692|M.leprae_Br4923 LALAGEFVPDAVNVDGGVVNEEVAPWLDLVCKLGVLVAALSDELPASLSV MMAR_1715|M.marinum_M LALAGEFVPDAVNIAGGAVNEEVAPWLDLACKLGVLAAALSDEPPVSLSV MUL_1952|M.ulcerans_Agy99 LALAGEFVPDAVNIAGGAVNEEVAPWLDLACKLGVLAAALSDEPPVSLSV MAV_3847|M.avium_104 LALAGEFVPDAVNVAGGTVNEEVAPWLDLVRKLGLLAATLSDGPPVSLSV TH_2037|M.thermoresistible__bu LALAGEFVPDAVNVGAGEVSEEVAPWVDLARKLGLLVGTLSGEPTATLQV *************: .* *.******:::. ***:* ..:: ...* * Mflv_4234|M.gilvum_PYR-GCK QVRGELASEEVEVLRLSALRGLFSAVIEDQVTFVNAPALATERGVEASID Mvan_2128|M.vanbaalenii_PYR-1 QVQGELASEEVEVLKLSALRGLFSAVIEHPVTFVNAPALASERGVEASIT MAB_3304c|M.abscessus_ATCC_199 DVRGELASEDVAVLKLSALRGLFSSVIEDQVTFVNAPSIAEERGVSAEIT MSMEG_2378|M.smegmatis_MC2_155 QVRGELASEDVEILKLSALRGLFSAVVDEQVTFVNAPALAADRGVTAEIS Mb3020c|M.bovis_AF2122/97 QVRGELAAEEVEVLRLSALRGLFSAVIEDAVTFVNAPALAAERGVTAEIC Rv2996c|M.tuberculosis_H37Rv QVRGELAAEEVEVLRLSALRGLFSAVIEDAVTFVNAPALAAERGVTAEIC MLBr_01692|M.leprae_Br4923 HVRGELASEDVEILRLSALRGLFSTVIEDAVTFVNAPALAAERGVSAEIT MMAR_1715|M.marinum_M QARGELASEDVEVLKLSALRGLFSAVVEGPVTFVNAPALAAERGVSVEIS MUL_1952|M.ulcerans_Agy99 QAGGELASEDVEVLKLSALRGLFSAVVEGPVTFVNAPALAAERGVSVEIS MAV_3847|M.avium_104 QVRGELASEDVEVLKLSALRGLFSAVVEGPVTFVNAPALAEERGVTAEIS TH_2037|M.thermoresistible__bu RVAGELASEDVEVLRLSALRGLFSTLTDQQVTYVNAPTLAAERGMQAELE . ****:*:* :*:*********:: : **:****::* :**: ..: Mflv_4234|M.gilvum_PYR-GCK TESESPNHRSVVDVRAVAADGSTVNVSGTLTGPQLVEKIVQINGRNLDLR Mvan_2128|M.vanbaalenii_PYR-1 TATESANHRSVVDVRAVAADGSTVNVAGTLTGPQLVEKIVQINGRNLELR MAB_3304c|M.abscessus_ATCC_199 TATESPNHRSVVDVRAVYADGSVINVAGTLSGPQLVQKIVQINGRNFDLR MSMEG_2378|M.smegmatis_MC2_155 TATESPNHRSVVDVRAVHADGSSINVAGTLSGPQLVEKIVQINGRNFDLR Mb3020c|M.bovis_AF2122/97 KASESPNHRSVVDVRAVGADGSVVTVSGTLYGPQLSQKIVQINGRHFDLR Rv2996c|M.tuberculosis_H37Rv KASESPNHRSVVDVRAVGADGSVVTVSGTLYGPQLSQKIVQINGRHFDLR MLBr_01692|M.leprae_Br4923 TGSESPNHRSVVDVRAVASDGSVVNIAGTLSGPQLVQKIVQVNGRNFDLR MMAR_1715|M.marinum_M KASESPNHRSVVDVRVVGADGSVVSVSGTLYGAQLTHKIVQINGRHFDLR MUL_1952|M.ulcerans_Agy99 KASESPNHRSVVDVRVVGADGSVVSVSGTLYGAQLTHKIVQINGRHFDLR MAV_3847|M.avium_104 TASESPNHRSVVDVRAVSHDGTVVNVAGTLSGPQLVEKIVQINGRNFDLR TH_2037|M.thermoresistible__bu KVSESPNYRSVVDVRAVSTDGTVTNVAGTLSGPQQVEKIVQINGRNFDLR . :**.*:*******.* **: .::*** *.* .****:***:::** Mflv_4234|M.gilvum_PYR-GCK AEGVNVIINYHDQPGALGKIGTLLGGANVNILAAQLSQDADGEGATIMLR Mvan_2128|M.vanbaalenii_PYR-1 AEGVNLIINYDDQPGALGKIGTLLGGAAVNILAAQLSQDADGIGATVMLR MAB_3304c|M.abscessus_ATCC_199 AEGVNLVINYADVPGALGKIGTVLGGAEVNIQAAQLSQDASGAAATIILR MSMEG_2378|M.smegmatis_MC2_155 AEGHNLIVNYSDKPGALGKIGTLLGGANVNILAAQLSQDASGDHATVMLR Mb3020c|M.bovis_AF2122/97 AQGINLIIHYVDRPGALGKIGTLLGTAGVNIQAAQLSEDAEGPGATILLR Rv2996c|M.tuberculosis_H37Rv AQGINLIIHYVDRPGALGKIGTLLGTAGVNIQAAQLSEDAEGPGATILLR MLBr_01692|M.leprae_Br4923 AQGMNLVIRYVDQPGALGKIGTLLGAAGVNIQAAQLSEDTEGPGATILLR MMAR_1715|M.marinum_M AEGTNLIVNYVDQPGALGKIGTLLGAAGVNIHAAQLSEDVEGPGATVLLR MUL_1952|M.ulcerans_Agy99 AEGTNLIVNYVDQPGALGKIGTLLGAAGVNIHAAQLSEDVEGPGATVLLR MAV_3847|M.avium_104 ARGINLVINYVDQPGALGKIGTLLGSAGVNIQAAQLSEDAEGPGATILLR TH_2037|M.thermoresistible__bu AEGVNLVMHYVDRPGALGKIGTLLGAADVNILAAQLSQDISGDGATLMLR *.* *:::.* * *********:** * *** *****:* .* **::** Mflv_4234|M.gilvum_PYR-GCK VDREVPADVLAGIGRDVNALTLEVVDLT Mvan_2128|M.vanbaalenii_PYR-1 LDREVPGEVLAAIGRDVNAVTLEVVDLT MAB_3304c|M.abscessus_ATCC_199 IDRTAPDAVLDEIRAAVGATTLELVDLS MSMEG_2378|M.smegmatis_MC2_155 VDTDVPDDVRAAIADAVGASTLEVVDLS Mb3020c|M.bovis_AF2122/97 LDQDVPDDVRTAIAAAVDAYKLEVVDLS Rv2996c|M.tuberculosis_H37Rv LDQDVPDDVRTAIAAAVDAYKLEVVDLS MLBr_01692|M.leprae_Br4923 LDQDVPGDVRSAIVAAVSANKLEVVNLS MMAR_1715|M.marinum_M LDQDVPEDVRSAIAAAVGANRLEVVDLS MUL_1952|M.ulcerans_Agy99 LDQDVPEDVRSAIAAAVGANRLEVVDLS MAV_3847|M.avium_104 LDQDVPADVRSAIGAAVGANKLEVVDLS TH_2037|M.thermoresistible__bu VNRDVPADVRDAIGAAVGASTLEVVDLS :: .* * * *.* **:*:*: