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M. thermoresistible (build 8) TH_3743 (-)

annotation: oxidoreductase, short chain dehydrogenase/reductase family protein
coordinates: 3780442 - 3781365
length: 308

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3743--100% (308)oxidoreductase, short chain dehydrogenase/reductase family protein
M. thermoresistible (build 8)TH_3887-4e-6750.52% (289) PUTATIVE short chain dehydrogenase
M. thermoresistible (build 8)TH_4198-1e-4842.35% (281) PUTATIVE putative oxidoreductase, short chain

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3532cfabG1e-12575.66% (304) 3-ketoacyl-(acyl-carrier-protein) reductase
M. gilvum PYR-GCKMflv_1553fabG1e-13983.28% (299) 3-ketoacyl-(acyl-carrier-protein) reductase
M. tuberculosis H37RvRv3502cfabG1e-12575.66% (304) 3-ketoacyl-(acyl-carrier-protein) reductase
M. leprae Br4923MLBr_02565fabG5e-3139.00% (259) 3-ketoacyl-(acyl-carrier-protein) reductase
M. abscessus ATCC 19977MAB_4156c-1e-12878.79% (297) putative short chain dehydrogenase/reductase
M. marinum MMMAR_4990fabG1e-13076.57% (303) short-chain type dehydrogenase/reductase
M. avium 104MAV_0654fabG1e-12778.75% (287) 3-ketoacyl-(acyl-carrier-protein) reductase
M. smegmatis MC2 155MSMEG_5903fabG1e-14084.90% (298) 3-ketoacyl-(acyl-carrier-protein) reductase
M. ulcerans Agy99MUL_4065fabG1e-12977.55% (294) 3-ketoacyl-(acyl-carrier-protein) reductase
M. vanbaalenii PYR-1Mvan_5205fabG1e-13882.84% (303) 3-ketoacyl-(acyl-carrier-protein) reductase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1553|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5205|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5903|M.smegmatis_MC2_155      --------------------------------------------------
TH_3743|M.thermoresistible__bu      --------------------------------------------------
Mb3532c|M.bovis_AF2122/97           --------------------------------------------------
Rv3502c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4990|M.marinum_M               --------------------------------------------------
MUL_4065|M.ulcerans_Agy99           --------------------------------------------------
MAV_0654|M.avium_104                --------------------------------------------------
MAB_4156c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02565|M.leprae_Br4923          MAPKCSSDLFSQIVSSGPGSFVAKQLGVPRPETLRRYRPSDAPLCGSLLI
                                                                                      

Mflv_1553|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5205|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5903|M.smegmatis_MC2_155      --------------------------------------------------
TH_3743|M.thermoresistible__bu      --------------------------------------------------
Mb3532c|M.bovis_AF2122/97           --------------------------------------------------
Rv3502c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4990|M.marinum_M               --------------------------------------------------
MUL_4065|M.ulcerans_Agy99           --------------------------------------------------
MAV_0654|M.avium_104                --------------------------------------------------
MAB_4156c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02565|M.leprae_Br4923          GGDGRLVEPLRATLEKDYDLVSNNLGGRWTDSFGGLVFDATGITAPAELK
                                                                                      

Mflv_1553|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5205|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5903|M.smegmatis_MC2_155      --------------------------------------------------
TH_3743|M.thermoresistible__bu      --------------------------------------------------
Mb3532c|M.bovis_AF2122/97           --------------------------------------------------
Rv3502c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4990|M.marinum_M               --------------------------------------------------
MUL_4065|M.ulcerans_Agy99           --------------------------------------------------
MAV_0654|M.avium_104                --------------------------------------------------
MAB_4156c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02565|M.leprae_Br4923          GLHNFFTPLLRNLGRCARVVVIGTTPDATTSTDERIAQRALEGFSRSLGK
                                                                                      

Mflv_1553|M.gilvum_PYR-GCK          -----------------------------------------------MPD
Mvan_5205|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5903|M.smegmatis_MC2_155      -----------------------------------------MTNDSHPSD
TH_3743|M.thermoresistible__bu      --------------------------------------------------
Mb3532c|M.bovis_AF2122/97           -------------------------------------------MKLTESN
Rv3502c|M.tuberculosis_H37Rv        -------------------------------------------MKLTESN
MMAR_4990|M.marinum_M               --------------------------------------------------
MUL_4065|M.ulcerans_Agy99           --------------------------------------------------
MAV_0654|M.avium_104                --------------------------------------------------
MAB_4156c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02565|M.leprae_Br4923          ELRRGATVALVYLSPDAKPAATGLESTMRFILSAKSAYVNGQVFYVGAAD
                                                                                      

Mflv_1553|M.gilvum_PYR-GCK          SASLRGTENDLSGRVAVVTGAAAGLGRAEAIGLAKAGATVVVNDMAAALD
Mvan_5205|M.vanbaalenii_PYR-1       -----MTHTDLSGHVAVVTGAAAGLGRAEAIGLAKAGATVVVNDIAPALD
MSMEG_5903|M.smegmatis_MC2_155      TGPDRGADLDLSGKVAVVTGAAAGLGRAEAIGLAKAGATVVVNDIAGALE
TH_3743|M.thermoresistible__bu      LTTNTPATNDLSGLVAVVTGAAAGLGRAEAIGLARAGATVVVNDIASALD
Mb3532c|M.bovis_AF2122/97           RSPRTTNTTDLSGKVAVVTGAAAGLGRAEALGLARLGATVVVNDVASALD
Rv3502c|M.tuberculosis_H37Rv        RSPRTTNTTDLSGKVAVVTGAAAGLGRAEALGLARLGATVVVNDVASALD
MMAR_4990|M.marinum_M               -MTSSTNVTDLSGRVAVVTGAAAGLGRAEAVGLARLGATVVVNDIGSALD
MUL_4065|M.ulcerans_Agy99           -------MTDLSGRVAVVTGAAAGLGRAEAVGLARLGATVVVNDIGSALD
MAV_0654|M.avium_104                ----------------MVTGAAAGLGRAEALGLARLGATVVVNDIATALD
MAB_4156c|M.abscessus_ATCC_199      --MSAIADADLSGRVAIVTGAAAGLGRAEAIGLARSGATVVVNDIAPALD
MLBr_02565|M.leprae_Br4923          STPPTNWDRPLENKVAIVTGAARGIGAAIAEVVARDGARVVAIDVESAAE
                                                    :***** *:* * *  :*: ** **. *:  * :

Mflv_1553|M.gilvum_PYR-GCK          KSDVLDEISS----AGSKGVAVAGDISQRSTADELVETADGLGG--LAIV
Mvan_5205|M.vanbaalenii_PYR-1       KSDVLDEIAA----AGSKGVAVAGDISQRSTADELVETADGLGG--LAIV
MSMEG_5903|M.smegmatis_MC2_155      GSDVLDEIAA----AGSKGVAVAGDISQRSTADELVETAEGLGG--LDIV
TH_3743|M.thermoresistible__bu      TSDVLDEIAA----AGSKGVAVAGDISQRATADELVQTADNLGG--LGIV
Mb3532c|M.bovis_AF2122/97           ASDVVDEIGAAAADAGAKAVAVAGDISQRATADELLASAVGLGG--LDIV
Rv3502c|M.tuberculosis_H37Rv        ASDVVDEIGAAAADAGAKAVAVAGDISQRATADELLASAVGLGG--LDIV
MMAR_4990|M.marinum_M               ASDVIDEISA----VGAKAIAVAGDISQRATADELIATADGLGG--LDVV
MUL_4065|M.ulcerans_Agy99           ASDVIDEISA----VGAKAIAVAGDISQRATADELIATADGLGG--LDVV
MAV_0654|M.avium_104                ASDVIDEINA----AGSKAVAVAGDISERATADELVAQADGLGG--LDIV
MAB_4156c|M.abscessus_ATCC_199      KSDVLDEIAA----AGSKGVTVAGDIGERATADELISTAESLGG--LHVV
MLBr_02565|M.leprae_Br4923          ALDETANRVG--------GTTLSLDVTADDAVDKITEHLHDYQGGHADIL
                                      *   :  .        . ::: *:    :.*::     .  *    ::

Mflv_1553|M.gilvum_PYR-GCK          VNNAGITRDRILFNMTDEEWDAVIAVHLRGHFLLTRNAATYWRSKAKEG-
Mvan_5205|M.vanbaalenii_PYR-1       VNNAGITRDRILFNMTDEEWDAVIAVHLRGHFLLTRNAATYWRSKAKQGG
MSMEG_5903|M.smegmatis_MC2_155      VNNAGITRDRILFNMSDEEWDAVIAVHLRGHFLLTRNAAAYWRSKAKAG-
TH_3743|M.thermoresistible__bu      VNNAGITRDKMLFNMSDEDWDAVIAVHLRGHFLLTRNAAAYWRAKAKES-
Mb3532c|M.bovis_AF2122/97           VNNAGITRDRMLFNMSDEEWDAVIAVHLRGHFLLTRNAAAYWRDKAKDAE
Rv3502c|M.tuberculosis_H37Rv        VNNAGITRDRMLFNMSDEEWDAVIAVHLRGHFLLTRNAAAYWRDKAKDAE
MMAR_4990|M.marinum_M               VNNAGITRDRMLFNMTDEDWDQVIGVHLRGHFLLTRNAATYWRQKAKAA-
MUL_4065|M.ulcerans_Agy99           VNNAGITRDRMLFNMTDEDWDQVIGVHLRGHFLLTRNAATYWRQKAKAA-
MAV_0654|M.avium_104                VNNAGITRDRMLFNMSDEEWDLVIAVHLRGHFLLTRNAAAYWRSRAKEA-
MAB_4156c|M.abscessus_ATCC_199      VNNAGITRDRMLFNMSDEEFDAVIHVHLRGHFLLTRNAATYWRGASKAA-
MLBr_02565|M.leprae_Br4923          VNNAGITRDKLLANMDDCRWDAVLEVNLLAPQRLTEGLVGNG--------
                                    *********::* ** *  :* *: *:* .   **.. .           

Mflv_1553|M.gilvum_PYR-GCK          ----DGTIYGRIINTSSEAGLSGPVGQPNYGAAKAGITALTLSAARALER
Mvan_5205|M.vanbaalenii_PYR-1       PGVENGQIYGRIINTSSEAGLSGPVGQPNYGAAKAGITALTLSAARALGR
MSMEG_5903|M.smegmatis_MC2_155      ----DGTVYGRVINTSSEAGLSGPVGQPNYGAAKAGITALTLSAARALER
TH_3743|M.thermoresistible__bu      ----GGQVYGRIINTSSEAGLSGPIGQANYGAAKAGITALTLTAARALER
Mb3532c|M.bovis_AF2122/97           ----GGSVFGRLVNTSSEAGLVGPVGQANYAAAKAGITALTLSAARALGR
Rv3502c|M.tuberculosis_H37Rv        ----GGSVFGRLVNTSSEAGLVGPVGQANYAAAKAGITALTLSAARALGR
MMAR_4990|M.marinum_M               ----GGSIFGRLVNTSSEAGLVGPVGQANYGAAKAGITALTLSAARALGR
MUL_4065|M.ulcerans_Agy99           ----GGSIFGRLVNTSSEAGLVGPVGQANYGAAKAGITALTLSAARALGR
MAV_0654|M.avium_104                ----GGRIFGRIVNTASEAGLVGPVGQANYGAAKAGIISLTLTAARALGR
MAB_4156c|M.abscessus_ATCC_199      ----GAPTYGRLINTSSEAGLLGPEGQANYGAAKAGITALTLSAARALGR
MLBr_02565|M.leprae_Br4923          ----SISKGGRVIVLSSMAGIAGNRGQTNYATAKAGVIGLTQALAPGLAE
                                        .    **::  :* **: *  **.**.:****: .** : * .* .

Mflv_1553|M.gilvum_PYR-GCK          FGVRANAIAP-RARTAMTAGVFGDAPELADGAVDPLS---PEHVVNLVRF
Mvan_5205|M.vanbaalenii_PYR-1       FGVRANAIAP-RARTAMTAGVFGDAPELPEGAVDPLS---PDHVVNLVRF
MSMEG_5903|M.smegmatis_MC2_155      FGVRANAIAP-RARTAMTAGVFGDAPELAEGQMDPLS---TDHVVTLVQF
TH_3743|M.thermoresistible__bu      YGVRANAIAP-RARTAMTAAVFGDEPELAEGQIDPLS---PEHVVTLVRF
Mb3532c|M.bovis_AF2122/97           YGVCANVICP-RARTAMTADVFGAAPDVEAGQIDPLS---PQHVVSLVQF
Rv3502c|M.tuberculosis_H37Rv        YGVCANVICP-RARTAMTADVFGAAPDVEAGQIDPLS---PQHVVSLVQF
MMAR_4990|M.marinum_M               YGVCANAICP-RARTAMTADVFGATPDVAAGEIDPLS---PEHVVTLVQF
MUL_4065|M.ulcerans_Agy99           YGVCANAICP-RARTAMTADVFGATPDVAAGEIDPLS---PEHVVTLVQF
MAV_0654|M.avium_104                YGVCANAICP-RARTAMTADVFGDAPEVPAGGVDPLS---PEHVVNLVTF
MAB_4156c|M.abscessus_ATCC_199      YGVRANAIAP-RARTAMTADVFGDAP---EDSIDPLS---PEHVVTLVRY
MLBr_02565|M.leprae_Br4923          KGITINAVAPGFIETQMTAAIPLATREVGRRLNSLLQGGLPVDVAETIAY
                                     *:  *.:.*   .* *** :            . *.   . .*.  : :

Mflv_1553|M.gilvum_PYR-GCK          LASPASEGVNGQLFIVYGPTVTLIAAPTAERQFSADGDAWDPSALSGTLQ
Mvan_5205|M.vanbaalenii_PYR-1       LASPAAEGVNGQLFIVYGPTVTLMAAPTAERQFSADGAEWDPADLSDTLR
MSMEG_5903|M.smegmatis_MC2_155      LAAPASEGVNGQLFIVYGPSVTLVAAPTAEKQFVADEDAWEPADLSVTLR
TH_3743|M.thermoresistible__bu      LASPASEAVNGQLFIVYGPTVTLVAAPTAERRFEARADAWDPADLSETLR
Mb3532c|M.bovis_AF2122/97           LASPAAAEVNGQVFIVYGPQVTLVSPPHMERRFSADGTSWDPTELTATLR
Rv3502c|M.tuberculosis_H37Rv        LASPAAAEVNGQVFIVYGPQVTLVSPPHMERRFSADGTSWDPTELTATLR
MMAR_4990|M.marinum_M               LASPAAAAVNGQLFIVYGPQVTLVAAPTAEHKFSADGPAWEPGQLTDTLH
MUL_4065|M.ulcerans_Agy99           LASPAAAAVNGQLFIVYGPQVTLVAAPTAEHKFSADGPAWEPGQLTDTLH
MAV_0654|M.avium_104                LSSPAAAEVNGQVFIVYGPQVTLVAAPTAEHKFSAQGPAWDPAELSATLQ
MAB_4156c|M.abscessus_ATCC_199      LAAPAAEAVNGQLFIVYGPTVTLLAAPTVEAKFTADSDAWDPSALNSTLA
MLBr_02565|M.leprae_Br4923          FAIPASNAVTGNVIRVCGQAMLGA--------------------------
                                    :: **:  *.*::: * *  :                             

Mflv_1553|M.gilvum_PYR-GCK          GYFAERDPGRSFSAAMGLGDPV
Mvan_5205|M.vanbaalenii_PYR-1       NYFADRDPERSFSAAMGLGDPH
MSMEG_5903|M.smegmatis_MC2_155      DYFADRDPERGFSATALMESRD
TH_3743|M.thermoresistible__bu      SYFADRDPNRGFSATELMGVTD
Mb3532c|M.bovis_AF2122/97           DYFAGRDPEQSFSATDLMRQ--
Rv3502c|M.tuberculosis_H37Rv        DYFAGRDPEQSFSATDLMRQ--
MMAR_4990|M.marinum_M               DYFAGRNPEHNFSASSLMA---
MUL_4065|M.ulcerans_Agy99           DYFAGRNPEHNFSASSLMA---
MAV_0654|M.avium_104                DYFAGRDPEHNFSASALMEQ--
MAB_4156c|M.abscessus_ATCC_199      DFFAGHDPKRTFSATALMVED-
MLBr_02565|M.leprae_Br4923          ----------------------