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M. thermoresistible (build 8) TH_3677 (-)

annotation: aminotransferase
coordinates: 2905102 - 2906166
length: 355

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3677--100% (355)aminotransferase
M. thermoresistible (build 8)TH_1662hisC25e-5035.74% (333) PROBABLE HISTIDINOL-PHOSPHATE AMINOTRANSFERASE HISC2
M. thermoresistible (build 8)TH_3588-5e-2229.22% (332) PUTATIVE histidinol-phosphate aminotransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3800hisC21e-5238.39% (336) putative aminotransferase
M. gilvum PYR-GCKMflv_1195-3e-4836.53% (323) putative aminotransferase
M. tuberculosis H37RvRv3772hisC21e-5238.39% (336) putative aminotransferase
M. leprae Br4923MLBr_01258hisC9e-2228.40% (338) histidinol-phosphate aminotransferase
M. abscessus ATCC 19977MAB_2168-1e-8049.53% (317) putative aminotransferase
M. marinum MMMAR_5326hisC24e-4635.69% (339) histidinol-phosphate aminotransferase HisC2
M. avium 104MAV_4421-1e-11866.36% (327) histidinol-phosphate aminotransferase
M. smegmatis MC2 155MSMEG_1491-1e-11462.95% (332) histidinol-phosphate aminotransferase 2
M. ulcerans Agy99MUL_4407hisC26e-4635.69% (339) putative aminotransferase
M. vanbaalenii PYR-1Mvan_1355-1e-12064.55% (330) aminotransferase, class I and II

CLUSTAL 2.0.9 multiple sequence alignment


Mb3800|M.bovis_AF2122/97            ---------MTARLRPELAGLP--------VYVPGKTVPGAIKLASNETV
Rv3772|M.tuberculosis_H37Rv         ---------MTARLRPELAGLP--------VYVPGKTVPGAIKLASNETV
MMAR_5326|M.marinum_M               ---------MTARLRPVLAGLP--------VYVPGKTVPGAIKLASNETV
MUL_4407|M.ulcerans_Agy99           ---------MTAHLRPVLAGLP--------VYVPGKTVPGAIKLASNETV
Mflv_1195|M.gilvum_PYR-GCK          MRAGHKLSQVSARLRPELADLP--------AYTPGRTVPGAIKIASNETV
TH_3677|M.thermoresistible__bu      -------MTSLIEAPPAERSLPGRRQPDTTPVVPSAVDP--MALSLNESP
MAV_4421|M.avium_104                ---------MLTVPRPADGGIG--------EALPDAVDP--FALSLNENP
MSMEG_1491|M.smegmatis_MC2_155      -----------------MEAVD---------ALPPAVNP--LALSLNEFP
Mvan_1355|M.vanbaalenii_PYR-1       ----------MASRDTLAEAVT---------ALPRAVDP--MALSLNEFP
MAB_2168|M.abscessus_ATCC_1997      -----------------MGREG-----------PVTVSP--LRLALNENP
MLBr_01258|M.leprae_Br4923          ----------MNVPEPTLDDLPLRDNLRGKSPYGAMQLLVPVLLNTNENP
                                                                             . :  **  

Mb3800|M.bovis_AF2122/97            FGP----LPSVRAAIDRATDTVNRYPDNGCVQLKAALARHLG----PDFA
Rv3772|M.tuberculosis_H37Rv         FGP----LPSVRAAIDRATDTVNRYPDNGCVQLKAALARHLG----PDFA
MMAR_5326|M.marinum_M               FGP----LPSVRAAIEHATQSINRYPDNGCLAVKAALARHVSSLSAADFG
MUL_4407|M.ulcerans_Agy99           FGP----LPSVRAAIEHATQSINRYPDNGCLAVKAALARHVSSLSAADFG
Mflv_1195|M.gilvum_PYR-GCK          HGP----LPSVRAAIADAVGGINRYPDNGYVDLNERLAKYVG------FA
TH_3677|M.thermoresistible__bu      FPP----LPAVRVALIEAVSAANRYPEFLPERLRSLIAERIG------VP
MAV_4421|M.avium_104                FPP----LPAVRAALIRSVCTANRYPEFLPERLRGVIAEHIG------VP
MSMEG_1491|M.smegmatis_MC2_155      YPP----LPAVKAALSAAVDAANRYPEFLPERLRSLIAGRVG------VD
Mvan_1355|M.vanbaalenii_PYR-1       FPP----LPAVRTALAASLDCLNRYPEFLPHRLRSLIAGRLG------AD
MAB_2168|M.abscessus_ATCC_1997      YRP----LPSVRDALRHDLAEVNRYPEFLPVVLPRLIADRVG------MT
MLBr_01258|M.leprae_Br4923          HPPTKALVDDVVRSVQKVAVDLHRYPDRDAVALRQDLASYLTAQTGIRLG
                                    . *    :  *  ::       :***:     :   :*  :         

Mb3800|M.bovis_AF2122/97            PEHVAVGCGSVSLCQQLVQVTASVGDEVVFGWRSFELYPPQVRVAGAIPI
Rv3772|M.tuberculosis_H37Rv         PEHVAVGCGSVSLCQQLVQVTASVGDEVVFGWRSFELYPPQVRVAGAIPI
MMAR_5326|M.marinum_M               PEHIAVGCGSVSLCQQLVQITASVGDEVIFGWRSFELYPPQVQVAGATAI
MUL_4407|M.ulcerans_Agy99           PEHIAVGCGSVSLCQQLVQITASVGDEVIFGWRSFELYPPQVQVAGATAI
Mflv_1195|M.gilvum_PYR-GCK          PENISVGCGSVSLCQQLIQITATVGDEVLFGWRSFEIYPLQVRTAGATPV
TH_3677|M.thermoresistible__bu      PDQVILGGGATGVMLQVLHAIADEHDRIVMATPTFEGYPIVARMRRLEPV
MAV_4421|M.avium_104                AELVVLGAGATGVMLQVLQALTAPGDAIAMATPTFDGYPIVARMARLNTI
MSMEG_1491|M.smegmatis_MC2_155      EGQVIIGVGATGVIMQVLHAVTSPGDTMVMSAPTFDGYPIFAQMARLRSV
Mvan_1355|M.vanbaalenii_PYR-1       PEQVVIGAGATGVLMQVLGAVTSPGDTIVMSSPTFDGYPILADMARLRPV
MAB_2168|M.abscessus_ATCC_1997      PEEVVVGVGATGVALQVLQALCKPGDSLVFAHPTFDGYPILADIAGLIQV
MLBr_01258|M.leprae_Br4923          VENIWAANGSNEILQQLLQAFGGPGRSAIGFVPSYSMHPIIADGTHTEWL
                                       :  . *:  :  *::               ::. :*  .       :

Mb3800|M.bovis_AF2122/97            QVPLTDHTFDLYAMLAAVTDRTR--LIFVCNPNNPTSTVVGPDALARFVE
Rv3772|M.tuberculosis_H37Rv         QVPLTDHTFDLYAMLATVTDRTR--LIFVCNPNNPTSTVVGPDALARFVE
MMAR_5326|M.marinum_M               QVPLTNHTFDLEAMLAAVTERTR--LIIVCNPNNPTSTVVQPEALAEFVR
MUL_4407|M.ulcerans_Agy99           QVPLTNHTFDLEAMLAAVTERTR--LIIVCDPNNPTSTVVQPEALAEFVR
Mflv_1195|M.gilvum_PYR-GCK          QVPLTDHTFDLDAMLAAITDRTR--LIFVCNPNNPSSTVVDPGALARFVA
TH_3677|M.thermoresistible__bu      EVPLAPDGRHDLTAMAEAAEHAR--VVALCRPHNPTGTVEPAAAIEGFLS
MAV_4421|M.avium_104                AVALDEHGQHDLDGLADAAARAR--VVVLCRPHNPTGTVESAAAVFRFLR
MSMEG_1491|M.smegmatis_MC2_155      TVDLDVYGHHNLHAMADAARDAR--VVVVCRPHNPTGTIEPAEDIERFLL
Mvan_1355|M.vanbaalenii_PYR-1       AVPLDAHGHHDLDAMADAAAQAR--VVVVCRPHNPTGTVESVADVERFLT
MAB_2168|M.abscessus_ATCC_1997      PIPLADNGMTDLDELLGAAYDADDAALVLCRPHNPTGTLIPADQVYEFVR
MLBr_01258|M.leprae_Br4923          ETVRADDFSLDVEAAVTAVADRKPDVVFIASPNNPSGQSISLADLRRLLD
                                                      .       : :. *:**:.       :  :: 

Mb3800|M.bovis_AF2122/97            A-VPAHILIAIDEAYVEYIRDGMRPDSLGLVRAHN-NVVVLRTFSKAYGL
Rv3772|M.tuberculosis_H37Rv         A-VPAHILIAIDEAYVEYIRDGMRPDSLGLVRAHN-NVVVLRTFSKAYGL
MMAR_5326|M.marinum_M               S-VPPHILVAIDEAYVEYLRDGTVPDSPHLVRTHS-NVVVLRTFSKAYGL
MUL_4407|M.ulcerans_Agy99           S-VPPHILVAIDEAYVEYLRDGTVPDSPHLVRTHS-NVVVLRTFSKAYGL
Mflv_1195|M.gilvum_PYR-GCK          A-VPPHILVVLDEAYIEYVRGDLVPDSFGLVRAHS-NVVVLRTFSKAYGL
TH_3677|M.thermoresistible__bu      R-LSADTVVLIDEAYVEFVAPGHRLDAVGLIRRFP-NVVGVRTFSKAYGL
MAV_4421|M.avium_104                R-VPRDTVVLLDEAYVEFTAPEHRIDVAALVACFP-NVVVVRTFSKAYGL
MSMEG_1491|M.smegmatis_MC2_155      ESIPEDTVVLLDEAYAEFLGPANRIDGPRLVERFR-NVVVVRTFSKAYGL
Mvan_1355|M.vanbaalenii_PYR-1       R-VGRDTVVLLDEAYVEFLAPEYRIDANALVRRFG-NVVVVRTFSKAYGL
MAB_2168|M.abscessus_ATCC_1997      Q-APPTSVVVLDEAYIEFVDPDEHLDIPGLLRLHP-NLVVLRTFSKAYGL
MLBr_01258|M.leprae_Br4923          V---VPGILIVDEAYGEFSS---RPSAVALVGEYPTKIVVTRTTSKAFAF
                                           :: :**** *:       .   *:  .  ::*  ** ***:.:

Mb3800|M.bovis_AF2122/97            AGLRIGYAIGHPDVITALDKVYVPFTVSSIGQAAAIASLDAADELLARTD
Rv3772|M.tuberculosis_H37Rv         AGLRIGYAIGHPDVITALDKVYVPFTVSSIGQAAAIASLDAADELLARTD
MMAR_5326|M.marinum_M               AGLRVGYAVGQPDVIAALDKVYVPFTVSSLAQAAAIASVQAADELLARTD
MUL_4407|M.ulcerans_Agy99           AGLRVGYAVGQPDVIAPLDKVYVPFTVSSLAQAAAIASVQAADELLARTD
Mflv_1195|M.gilvum_PYR-GCK          AGLRIGYAVADPDIVTALSKVYVPFTATTVSQAAAIACLDAADELLERTD
TH_3677|M.thermoresistible__bu      AGLRIGYAFGSPQLAARLWAMQLPFGMSITSLAAVAASYGADRQLRRRIR
MAV_4421|M.avium_104                AGLRIGYGVASPRLARPLWDQQLPFGIAITSLLAVTASYRAEDELSRRIR
MSMEG_1491|M.smegmatis_MC2_155      AGLRIGYGFCAPQLARQLWTMQLPFGIGLPALVAVAASYDAEGQLRQRIR
Mvan_1355|M.vanbaalenii_PYR-1       AGLRVGYGFCAPALGRTLWTMQLPFGTSLAALVAVAASFDADSQLRQRVR
MAB_2168|M.abscessus_ATCC_1997      AGLRIGYGLAAPAVCGVIRRYQLPFGMNRAAAVAVAASYAAEGELRVRVD
MLBr_01258|M.leprae_Br4923          AGGRLGYLIATPALVEAMLLVRLPYHLSSVTQAAARAALRHADDTLGSVA
                                    ** *:** .  * :   :    :*:        *. *.     :      

Mb3800|M.bovis_AF2122/97            TVVAERARVSAELRAAGFTLPPSQANFVWLPLGSRTQDFVEQAADARIVV
Rv3772|M.tuberculosis_H37Rv         TVVAERARVSAELRAAGFTLPPSQANFVWLPLGSRTQDFVEQAADARIVV
MMAR_5326|M.marinum_M               AVVAERGRVSAELRAAGFTVPPSQANFVWLPLEDRTTDFVTQAAKAHIVV
MUL_4407|M.ulcerans_Agy99           AVVAERGRVSAELRAAGFTVPPSQANFVWLPLEDRTTDFVTQAAKAHIVV
Mflv_1195|M.gilvum_PYR-GCK          AVVAERTRVSAALREAGYDLPPSQANFVWLPLVGRAQQFAADAADARIIV
TH_3677|M.thermoresistible__bu      MITTERRYLQTQLRALGVASTDAHANFVYLPAD--GRCWPEVFAGTDLRV
MAV_4421|M.avium_104                SITAERRRLRMRLSALGVYTTDAHANFVYLPPDPQGRAWQRVFARGGVRA
MSMEG_1491|M.smegmatis_MC2_155      MISAERRFLQMRLRSMGVYSTDGQANFVYLPAT--GVPWHDVFDDAGLKV
Mvan_1355|M.vanbaalenii_PYR-1       SISAERRRLQMRLRALGAYTTDAHANFVYLPSG--VTSWPEVFDGTGLQV
MAB_2168|M.abscessus_ATCC_1997      SIVYERDRLRARLAQMGAHIPESHANFVYLPARGDGERWMSILGTGDVVA
MLBr_01258|M.leprae_Br4923          ALIAERERVTKSLVHMGFRVIPSDANFVLFGHFSDAAGAWQHYLDTGVLI
                                     :  **  :   *   *     ..**** :                 :  

Mb3800|M.bovis_AF2122/97            RPYGTDG-VRVTVAAPEENDAFLRFARRWRSDQ------------
Rv3772|M.tuberculosis_H37Rv         RPYGTDG-VRVTVAAPEENDAFLRFARRWRSDQ------------
MMAR_5326|M.marinum_M               RPYGADG-VRVTIAAPEENDALLRFARCWITHRDGAR--------
MUL_4407|M.ulcerans_Agy99           RPYGADG-VRVTIAAPEENDALLRFARCWITHRDGAR--------
Mflv_1195|M.gilvum_PYR-GCK          RPYGEDG-VRVTVASPDENDMFLDFARDWIARP------------
TH_3677|M.thermoresistible__bu      KHCPDGG-VRITVGDRSSTGAVLA------AIRGQR---------
MAV_4421|M.avium_104                RYYPDGA-ARLTVGSRASTVAVLS------AVGKATLERQVR---
MSMEG_1491|M.smegmatis_MC2_155      RHYADGG-VRVTVGTRESTREVLR------ATRLALR--------
Mvan_1355|M.vanbaalenii_PYR-1       RHYAGGG-VRITVGSRASTRAVVH------AVAAAMG--------
MAB_2168|M.abscessus_ATCC_1997      KEYSDGG-VRLTVGDPREMAIVARRLLEVDEIGESAVSRMSRPAS
MLBr_01258|M.leprae_Br4923          RDVGIPGYLRATTGLAEENDAFLKASSEIAATELAPATTLGAS--
                                    :     .  * * .   .   .