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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3475 | - | - | 100% (217) | NAD dependent epimerase/dehydratase family protein |
| M. thermoresistible (build 8) | TH_1114 | - | 8e-06 | 27.95% (161) | PROBABLE CHOLESTEROL DEHYDROGENASE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3752 | - | 2e-05 | 26.11% (157) | putative oxidoreductase |
| M. gilvum PYR-GCK | Mflv_1761 | - | 1e-43 | 44.44% (216) | NAD-dependent epimerase/dehydratase |
| M. tuberculosis H37Rv | Rv3725 | - | 2e-05 | 26.11% (157) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3427 | - | 1e-42 | 44.86% (214) | hypothetical protein MAB_3427 |
| M. marinum M | MMAR_4327 | - | 9e-81 | 67.29% (214) | hypothetical protein MMAR_4327 |
| M. avium 104 | MAV_1263 | - | 7e-86 | 72.73% (209) | NAD dependent epimerase/dehydratase family protein |
| M. smegmatis MC2 155 | MSMEG_2941 | - | 2e-41 | 45.12% (215) | NAD dependent epimerase/dehydratase family protein |
| M. ulcerans Agy99 | MUL_0137 | - | 3e-79 | 65.89% (214) | hypothetical protein MUL_0137 |
| M. vanbaalenii PYR-1 | Mvan_4986 | - | 9e-43 | 44.04% (218) | NAD-dependent epimerase/dehydratase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4327|M.marinum_M ----MTRVVVFGGHGKVALLLGHILADRGDQVSSVFRNPD-HRDDIAATG
MUL_0137|M.ulcerans_Agy99 ----MTPVVVFGGHGKVALLLGHILADRGDQVSSVFRNPD-HRDDIAATG
MAV_1263|M.avium_104 --------MIVGGHGKVALQLSAILTQRGDAVTSLFRNPD-HADDVAATG
TH_3475|M.thermoresistible__bu ----MARIVIIGGHGQVAMHLSRILSERGDQVTSVFRNPN-HAEEVMVTG
Mflv_1761|M.gilvum_PYR-GCK -----MRVVIAGGHGKIALITSRLLSARGDSVAGLIRNPA-HEDDLRVTG
Mvan_4986|M.vanbaalenii_PYR-1 -----MRVVIAGGHGKIALITARLLSVRGDSVAGLIRNPD-HADDLRVAG
MSMEG_2941|M.smegmatis_MC2_155 -----MRVVIAGGHGKIALILERLLADRGDSVVGLIRNPE-HAADVKAAG
MAB_3427|M.abscessus_ATCC_1997 ---MPQKVVIAGGHGQIAAHLIRLLAARGDTAVALIRNPD-HAADVEAWG
Mb3752|M.bovis_AF2122/97 MQNATMRVLVTGGTGFVGGWTAKAIADAGHSVRFLVRNPARLKTSVAKLG
Rv3725|M.tuberculosis_H37Rv MQNATMRVLVTGGTGFVGGWTAKAIADAGHSVRFLVRNPARLKTSVAKLG
:: ** * :. :: *. . :.*** .: *
MMAR_4327|M.marinum_M ATPVQADIEGLDT-AALAGLLTGHDAVVFSAGAG---GGNPARTYAVDRD
MUL_0137|M.ulcerans_Agy99 ATPVQADIEGLDT-AALAGLLTGHDAVVFSAGAG---GGNPARTYAVDRD
MAV_1263|M.avium_104 AKPVVADIERLDT-DALAGLLAGHDAVVFSAGAG---GGNPARTYAVDRD
TH_3475|M.thermoresistible__bu AQPLRADLEQLDT-DTLTEVLSGHDAVVFSAGAG---GGNPTRTYAVDRD
Mflv_1761|M.gilvum_PYR-GCK AEPVVLDLEDTTN-GVVSSHLRGADAVIFAAGAGP--GSGAARKETVDRD
Mvan_4986|M.vanbaalenii_PYR-1 AEPVVVDLENTTN-GVVSTHLRGADAVIFAAGAGP--GSGAARKETVDRD
MSMEG_2941|M.smegmatis_MC2_155 AEPIVLDLEKAAV-DEVAGAVRGADAVVFAAGAGP--GSGAARKQTVDRD
MAB_3427|M.abscessus_ATCC_1997 GLPLVLDLESTDA-DDVAGALAGADAAVFAAGAGP--GSGPARKDTVDRA
Mb3752|M.bovis_AF2122/97 VDVSDFAVADISDRDSVREALNGCDAVVHSAALVATDPRETSRMLSTNMA
Rv3725|M.tuberculosis_H37Rv VDVSDFAVADISDRDSVREALNGCDAVVHSAALVATDPRETSRMLSTNMA
: : : * **.:.:*. .:* :.:
MMAR_4327|M.marinum_M AAIRVIDAATRAGVQRFVMVSYFGAG-------PNHGVSVDDSFFPYAQA
MUL_0137|M.ulcerans_Agy99 AATRVIDAATRAGVQRFVMISYFGAG-------PNHGVSVDDSFFPYAQA
MAV_1263|M.avium_104 AAIRVVDAAARSGVKRFVMVSYFGAG-------PDHGVPQDDPFFPYAES
TH_3475|M.thermoresistible__bu AAIRVIDAAGKAGVSRFIMVSYFGAG-------PDHGVPEDSSFFPYAES
Mflv_1761|M.gilvum_PYR-GCK AAVLLADAAEAAGVQRYLMISAMGADA------NTPNDAADDVFVAYLRA
Mvan_4986|M.vanbaalenii_PYR-1 AAILLADAAEAAGVPRYVMVSSMGADA------AAPDDAGDDVFVAYLRA
MSMEG_2941|M.smegmatis_MC2_155 AAILLADAAEAAGVDRYVMVSALAADD------RSLDESYDEVFRVYMQA
MAB_3427|M.abscessus_ATCC_1997 AAVLLATAAEQAQVHRFIQISAFGAGE------PAPTEG-DESWIAYVIA
Mb3752|M.bovis_AF2122/97 GAQNVLGQAVELGMDPIVHVSSFTALFRPNLATLSADLPVAGGTDGYGQS
Rv3725|M.tuberculosis_H37Rv GAQNVLGQAVELGMDPIVHVSSFTALFRPNLATLSADLPVAGGTDGYGQS
.* : * : : :* : * * :
MMAR_4327|M.marinum_M KAAADAHLRA---SNLDWTVLGPSRLTMEPATGRISIG----TGKSGKAT
MUL_0137|M.ulcerans_Agy99 KAAADAHLRA---SNLDWTVLGPSRLTMEPATGRISIG----TGKSGKAT
MAV_1263|M.avium_104 KAAADAHLRA---SDLDWTILGPGRLTLDPPTGRIAVG----RGK---GE
TH_3475|M.thermoresistible__bu KAAADAHLRA---SELDWTILGPGRLTEEPATGKITVG----PEAAD-SE
Mflv_1761|M.gilvum_PYR-GCK KGAADDLIRSR--TELYATIVRPGQLTDDPGTGKVAIA----EHTG-RGK
Mvan_4986|M.vanbaalenii_PYR-1 KGAADDVIRAR--TSLLATIVRPGLLTDDEPTGRVRIA----EHTG-RGS
MSMEG_2941|M.smegmatis_MC2_155 KSEADANVRAR--SGLRTTIVRPGGLTNDAGTGLVRIA----ESTG-RGT
MAB_3427|M.abscessus_ATCC_1997 KTAAEEDLRTR--DRLDWTILRPGLLTDTAPTGSVTLS----ASKIERGS
Mb3752|M.bovis_AF2122/97 KAQIEIYARGLQDAGAPVNITYPGMVLGPPVGDQFGEAGEGVRSALWMHV
Rv3725|M.tuberculosis_H37Rv KAQIEIYARGLQDAGAPVNITYPGMVLGPPVGDQFGEAGEGVRSALWMHV
* : * .: *. : . . .
MMAR_4327|M.marinum_M VSRADVARVIAATLNDDSTIGRTIDFNNGDVPIATALAD-----------
MUL_0137|M.ulcerans_Agy99 VSRVDVARVIAATLNDDSTIGRTIDFNNGDVPIATALAD-----------
MAV_1263|M.avium_104 VSRADVASVAAAALADDSTIRRTIDFNNGDVPIAVALAG-----------
TH_3475|M.thermoresistible__bu VPREDVALVAAACLADDSTVRRTIEFNKGDTSIAEAVRAR----------
Mflv_1761|M.gilvum_PYR-GCK IPRADVAAVLVAVLDAPQTAGQTFELISGDTDIEVAVASLAVG-------
Mvan_4986|M.vanbaalenii_PYR-1 IPRADVAAVLVAVLDTPDTAGRTFEVISGDAAVADAVAALT---------
MSMEG_2941|M.smegmatis_MC2_155 VPREDVARVLVAVLDAPQTAGRTFELISGATPIDDALV------------
MAB_3427|M.abscessus_ATCC_1997 VPRADVAAVVAELLGAPNTVHEILFLTEGTAPIASAVAGL----------
Mb3752|M.bovis_AF2122/97 IPGRGAAWLIVDVRDVAALHAALLESGRGPRRYTAGGHRIPVPELAKILG
Rv3725|M.tuberculosis_H37Rv IPGRGAAWLIVDVRDVAALHAALLESGRGPRRYTAGGHRIPVPELAKILG
:. ..* : . : * .
MMAR_4327|M.marinum_M --------------------------------------------------
MUL_0137|M.ulcerans_Agy99 --------------------------------------------------
MAV_1263|M.avium_104 --------------------------------------------------
TH_3475|M.thermoresistible__bu --------------------------------------------------
Mflv_1761|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4986|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2941|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3427|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3752|M.bovis_AF2122/97 EVAGTTMLAVPVPDSALRVAGSVLDQAGPYLPFNTPFTAAGMQYYTQMPE
Rv3725|M.tuberculosis_H37Rv GSPAPRCWPSRCPIPRCVSRDRCWIKPGP-------------ICLSILRS
MMAR_4327|M.marinum_M ---------------------------------
MUL_0137|M.ulcerans_Agy99 ---------------------------------
MAV_1263|M.avium_104 ---------------------------------
TH_3475|M.thermoresistible__bu ---------------------------------
Mflv_1761|M.gilvum_PYR-GCK ---------------------------------
Mvan_4986|M.vanbaalenii_PYR-1 ---------------------------------
MSMEG_2941|M.smegmatis_MC2_155 ---------------------------------
MAB_3427|M.abscessus_ATCC_1997 ---------------------------------
Mb3752|M.bovis_AF2122/97 PDDSPSEKELGITYRDPRDTVADTVTALRGLGS
Rv3725|M.tuberculosis_H37Rv PRQVCS-----TTHRCRSPTIRRAKKN------