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M. thermoresistible (build 8) TH_3370 (-)

annotation: putative acyl-CoA dehydrogenase
coordinates: 132127 - 133410
length: 428

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_3370 - - 100% (428) putative acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_2939 - e-114 51.51% (431) PUTATIVE acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8) TH_2832 - e-104 47.95% (440) PUTATIVE putative acyl-CoA dehydrogenase domain protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0136c fadE1 1e-112 51.44% (418) acyl-CoA dehydrogenase FADE1
M. gilvum PYR-GCK Mflv_2451 - 1e-112 51.55% (419) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv0131c fadE1 1e-112 51.44% (418) acyl-CoA dehydrogenase FADE1
M. leprae Br4923 MLBr_00737 fadE25 2e-21 22.68% (388) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_4911c - 1e-117 51.21% (414) acyl-CoA dehydrogenase FadE
M. marinum M MMAR_0331 fadE1 1e-115 50.47% (424) acyl-CoA dehydrogenase FadE1
M. avium 104 MAV_5173 - 1e-115 51.42% (424) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_4826 - 1e-116 52.22% (427) putative acyl-CoA dehydrogenase
M. ulcerans Agy99 MUL_4790 fadE1 1e-112 50.00% (424) acyl-CoA dehydrogenase FadE1
M. vanbaalenii PYR-1 Mvan_4200 - 1e-113 51.06% (425) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_0331|M.marinum_M               -------------MWDFETDPEY-QAKLDWVQEFMVNELEPLDLVALDP-
MUL_4790|M.ulcerans_Agy99           -------------MWDFETDPEY-QAKLDWVQEFMVNELEPLDLVALDP-
MAV_5173|M.avium_104                -------------MWDFETDPEY-QAKLDWVEKFMAEELEPLDLVALDP-
Mb0136c|M.bovis_AF2122/97           MPVRRRAGERLPTVWDFETDPQY-QSKLDWVEKFMAEELEPLDLVALDP-
Rv0131c|M.tuberculosis_H37Rv        MPVRRRAGERLPTVWDFETDPQY-QSKLDWVEKFMAEELEPLDLVALDP-
MAB_4911c|M.abscessus_ATCC_199      ---------MTAMAWDFETDPEY-QELLDWADEFVRTEVEPLDYVFPNP-
Mflv_2451|M.gilvum_PYR-GCK          -------------MWSFETDPEY-QKVLDWADEFVREEVEPLDLAFPHQQ
Mvan_4200|M.vanbaalenii_PYR-1       -------------MWSFETDPEY-QKVLDWADEFVREEVEPLDLAFPHQQ
MSMEG_4826|M.smegmatis_MC2_155      ------------MAWDFETDPQY-QEVLDWADEFVREKVEPLDLVWPHLQ
TH_3370|M.thermoresistible__bu      ------------MAWDFSTEPEF-QEKLDWVKQFCEEKVEPLDHVFPHA-
MLBr_00737|M.leprae_Br4923          -------------MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAP-
                                                   .:. :* :    *   .:     :..*        

MMAR_0331|M.marinum_M               YDKKNPEMMAVLRPLQQQVKDQGLWAAHLRPELGGQGFGQVKLALLNEIL
MUL_4790|M.ulcerans_Agy99           YDKKNPEMMAVLRPLQQ-VKNQGLWAAHLRPEVGGQGFGQVKLALLNEIL
MAV_5173|M.avium_104                YDKKNAEMMAILRPLQQQVKDQGLWAAHLRPELGGQGFGQVKLALLNEIL
Mb0136c|M.bovis_AF2122/97           YDKKNADTMAILRPLQRQVKDQGLWAAHLRPELGGQGFGQVKLALLNEII
Rv0131c|M.tuberculosis_H37Rv        YDKKNADTMAILRPLQRQVKDQGLWAAHLRPELGGQGFGQVKLALLNEII
MAB_4911c|M.abscessus_ATCC_199      YDKSDTVAMDYVRPLKEEVKRRGLWACHLGPELGGPGYGQLKLALLNEIL
Mflv_2451|M.gilvum_PYR-GCK          FVPLDGKRREAIDPLKEEVRRRGLWATHLGADLGGQGYGQLKLALLNEIL
Mvan_4200|M.vanbaalenii_PYR-1       FVPLDGERRRAIDPLKEEVRRRGLWATHLGADLGGQGYGQLKLALLNEIL
MSMEG_4826|M.smegmatis_MC2_155      FTPLNEARRQVVDPLKEQVRRKGLWATHLGPELGGQGYGQLKLALLNEIL
TH_3370|M.thermoresistible__bu      VRSPDPVVKAYVRELQQEVRDQGLWAIFLDRELGGPGFGQLKLALLNEII
MLBr_00737|M.leprae_Br4923          HAADVDQRARFPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEV
                                                      :.  *: * .:  : ** * ..:  .:: * :

MMAR_0331|M.marinum_M               GRSRWAPSVFGCQAPDSGNAEILALFGTEDQKARYLQPLLDGEITSCYSM
MUL_4790|M.ulcerans_Agy99           GRSRWAPSVFGCQAPDSGNAEILALFGTEDQKARYLQPLLDGEITSCYSM
MAV_5173|M.avium_104                GRSRWAPSVFGCQAPDSGNAEILALFGTDEQKARYLQPLLDGEITSCYSM
Mb0136c|M.bovis_AF2122/97           GRSRWAPSAFGCQAPDSGNAEILALFGTDEQKARYLRPLLDGEITSCYSM
Rv0131c|M.tuberculosis_H37Rv        GRSRWAPSAFGCQAPDSGNAEILALFGTDEQKARYLRPLLDGEITSCYSM
MAB_4911c|M.abscessus_ATCC_199      GRSVWAPSIFGCQAPDTGNAEILAHYGTEAQKAKYLQPLMDGDIGSCYVM
Mflv_2451|M.gilvum_PYR-GCK          GRSQWAPIIFGCQAPDTGNAEIIAHYGTEEQKQRYLRPLLDGELFSCYSM
Mvan_4200|M.vanbaalenii_PYR-1       GRSQWAPVIFGCQAPDTGNAEIIAHYGTEEQKQKYLRPLLDGELFSCYSM
MSMEG_4826|M.smegmatis_MC2_155      GRSQWAPIVFGCQAPDTGNAEIIAHYGTDEQKERYLRPLLEGELFSSYSM
TH_3370|M.thermoresistible__bu      GRYPGAPQMFGAAAPDTGNIEMLAAYGTEEQKKRWLEPLLNQDIFSAYSM
MLBr_00737|M.leprae_Br4923          ARVDASASLIPAVN-KLGTMGLILR-GSEELKKQVLPSLAAEGAMASYAL
                                    .*   :.  : .   . *.  ::   *::  * : * .*      :.* :

MMAR_0331|M.marinum_M               TEPQGGSDPGSFVTAATRDGD---SWIINGEKWFSTNAKHASFFIVMAVT
MUL_4790|M.ulcerans_Agy99           TEPQGGSDPGSFVTAATRDGD---SWIINGEKWFSTNAKHASFFIVMAVT
MAV_5173|M.avium_104                TEPQGGSDPGQFVTAATRDGD---YWVINGEKWFSTNAKHASFFIVMAVT
Mb0136c|M.bovis_AF2122/97           TEPQGGSDPGLFVTAATRDAAGNGDWIINGEKWFSTNAKHASFFIVMAVT
Rv0131c|M.tuberculosis_H37Rv        TEPQGGSDPGLFVTAATRDAAGNGDWIINGEKWFSTNAKHASFFIVMAVT
MAB_4911c|M.abscessus_ATCC_199      TEPQGGSDPTLFKTTAVRDGD---EWILNGEKWFNSEARHAAFWIVMAVT
Mflv_2451|M.gilvum_PYR-GCK          TEPHAGADPTMFTTSAVRDGD---DWVINGWKFFSSNAATASFLIVMVVT
Mvan_4200|M.vanbaalenii_PYR-1       TEPHAGADPTMFTTSAVRDGD---DWVINGWKFFSSNAATASFLIVMVVT
MSMEG_4826|M.smegmatis_MC2_155      TEPHAGADPTLFTTRAVRDGD---DWVINGWKFFSSNAATASFLIVMVVT
TH_3370|M.thermoresistible__bu      TEPQGGSDPNLFETHAVRDGD---EWVINGEKWFTSAGRVADILFVMCTN
MLBr_00737|M.leprae_Br4923          SEREAGSDAASMRTRAKADGD---DWILNGFKCWITNGGKSTWYTVMAVT
                                    :* ..*:*.  : * *  *.     *::** * : : .  :    ** ..

MMAR_0331|M.marinum_M               NPQARTYEKMSLFIVPAETPGIEIVRNVGVGTESSKHASHGYVRYHDVRV
MUL_4790|M.ulcerans_Agy99           NPQARTYEKMSLFIVPAETPGIEIVRNVGVGTESSKHASHGYVRYHDVRV
MAV_5173|M.avium_104                NPEARTYDKMSLFIVPAETPGIEIVRNVGVGAESSSRASHGYVGYTDVRV
Mb0136c|M.bovis_AF2122/97           KPEARTYEKMSLFIVPADTPGIEIVRNVGVGAESTRHASHGYIRYHDVRV
Rv0131c|M.tuberculosis_H37Rv        KPEARTYEKMSLFIVPADTPGIEIVRNVGVGAESTRHASHGYIRYHDVRV
MAB_4911c|M.abscessus_ATCC_199      NTEVSPYQGMSMFIVDPNAPGVEIVRNITVHGFS---EDEAYTRFTNARI
Mflv_2451|M.gilvum_PYR-GCK          NPDVSAYQGMSMFLVPTDTPGVTIERNVGLYGEREGEGSHALIHYDNVRV
Mvan_4200|M.vanbaalenii_PYR-1       NREVSAYQGMSMFLVPTDTPGVKIERNIGLYGEGAEHGSHALIHYDNVRV
MSMEG_4826|M.smegmatis_MC2_155      NPDVSAYQGMSMFLVPTDTPGVEIVRNVGLYGERDNEGSHALIHYDNVRV
TH_3370|M.thermoresistible__bu      ----------GMFVVPRDTPGVEIMPEP---------RNHNHIIYRDVRV
MLBr_00737|M.leprae_Br4923          DPDKGAN-GISAFIVHKDDEGFSIGPKEKKLGIKG--SPTTELYFDKCRI
                                              . *:*  :  *. *  :                 : . *:

MMAR_0331|M.marinum_M               PADHVLGGEGQAFMIAQTRLGGGRIHHAMRTIALARRAFDMMCERAVSRQ
MUL_4790|M.ulcerans_Agy99           PADHVLGGEGQAFMTAQTRLGGGRIHHAMRTIALARRAFDMMCERAVSRQ
MAV_5173|M.avium_104                PADHVLGGEGQAFMIAQTRLGGGRIHHAMRTIALARSAFDMMCERAVSRK
Mb0136c|M.bovis_AF2122/97           PADHVLGGEGQAFMIAQTRLGGGRIHHAMRTIALARRAFDMMCERALSRQ
Rv0131c|M.tuberculosis_H37Rv        PADHVLGGEGQAFMIAQTRLGGGRIHHAMRTIALARRAFDMMCERALSRQ
MAB_4911c|M.abscessus_ATCC_199      PAENMLGAEGGAFAIAQTRLGGGRVHHAMRTVAQVRKAFDMMCERVVSRE
Mflv_2451|M.gilvum_PYR-GCK          PSEALLGGEGQAFAIAQTRLGGGRIHHAMRTIGLSRKALDMMCERALSRE
Mvan_4200|M.vanbaalenii_PYR-1       PAEALLGGEGQAFVIAQTRLGGGRIHHAMRTIGLSRKALDMMCERALSRE
MSMEG_4826|M.smegmatis_MC2_155      PAEALLGGEGQAFVIAQTRLGGGRIHHAMRTIGLARKALDMMCERALSRK
TH_3370|M.thermoresistible__bu      PLDHLLGPEDGAKVLAQRRLGGGRIHHAMRTIAQCNLAFDMMCERALSRK
MLBr_00737|M.leprae_Br4923          PGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRK
                                    * : ::*  . .   *   *.  *   . :::.  . *:*     . .*:

MMAR_0331|M.marinum_M               TRHGRLSDLQMTQEKVADSWIQIEQFRLLVLRTAWLIDKHHDYQKVRRDI
MUL_4790|M.ulcerans_Agy99           TRHGRLSDLQMTQEKVADSWIQIEQFRLLVLRTAWLIDKHHDYQKVRRDI
MAV_5173|M.avium_104                TRHGRLADFQMTQEKIADSWIQIEQFRLLVLRTAWLIDKHHDYQKVRRDI
Mb0136c|M.bovis_AF2122/97           TRHGRLADLQMTQEKIADSWIQIEQFRLLVLRTAWLIDKHHDYQKVRRDI
Rv0131c|M.tuberculosis_H37Rv        TRHGRLADLQMTQEKIADSWIQIEQFRLLVLRTAWLIDKHHDYQKVRRDI
MAB_4911c|M.abscessus_ATCC_199      ARGGTIAKLQMTQERIADSWIEMESFRLLVLRTAWLIDKHQDYLKVRKDI
Mflv_2451|M.gilvum_PYR-GCK          TQGSRLSDKQFVQGYIADSYAQLLQFRLMVLYTAWEIDKYNDYKKVRKDI
Mvan_4200|M.vanbaalenii_PYR-1       TQGSRLSDKQFVQGYIADSYAQLLQFRLMVLYTAWEIDKYNDYKKVRKDI
MSMEG_4826|M.smegmatis_MC2_155      TQGSRLSDKQFVQGYIADSYAQLLQFRLMVLYTAWEIDKYNDYKLVRKDI
TH_3370|M.thermoresistible__bu      SHGKVIAEHQMVQEKIAESYAMIRMLRLYVLETAWKIDQTST-QEARTDI
MLBr_00737|M.leprae_Br4923          QFGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLGFIS--
                                         ::  *  *  :*:    :   ** *  :*   ::           

MMAR_0331|M.marinum_M               AAVKVAMPQVLHDVVQRAMHLHGALGVSDEMPFVKMMVAAESLGIADGAT
MUL_4790|M.ulcerans_Agy99           AAVKVAMPQVLHDVVQRAMHLHGALGVSDEMPFVKMMVAAESLGIADGAT
MAV_5173|M.avium_104                AAVKVAMPQVLHDVAQRALHLHGALGVSDEMPFVKMLVAAESLGIADGAT
Mb0136c|M.bovis_AF2122/97           AAVKVAMPQVLHDVVQRAMHLHGALGVSDEMPFVKMMLAAESLGIADGAT
Rv0131c|M.tuberculosis_H37Rv        AAVKVAMPQVLHDVVQRAMHLHGALGVSDEMPFVKMMLAAESLGIADGAT
MAB_4911c|M.abscessus_ATCC_199      SAIKAAMPKVMHDVAQRALHLHGSLGVSEEMPLAKMFLYSEVMGLVDGPT
Mflv_2451|M.gilvum_PYR-GCK          AAVKVVMPTVLHDIAWRAMQVHGALGVTNEVPFLGMVTGAAVMGLADGPT
Mvan_4200|M.vanbaalenii_PYR-1       AAVKVVMPTVLHDIAWRAMQVHGALGVTNEVPFLGMVTGAAVMGLADGPT
MSMEG_4826|M.smegmatis_MC2_155      AAVKVVMPTVLHDIAWRAMQVHGALGVTNEMPFLGMVTGAAVMGLADGPT
TH_3370|M.thermoresistible__bu      AAVKFTMARVLREVSFNALHILGSLGTTDLTPLQAMYANAPTMGIADGVD
MLBr_00737|M.leprae_Br4923          AASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTN
                                    :* *   . :  ::   *::: *. * :.  *.  :   :    : :*  

MMAR_0331|M.marinum_M               ELHKMTVARRTLRQYEPVTTPFPSQHIPTRRAAAEARLAERLEHSIAEF-
MUL_4790|M.ulcerans_Agy99           ELHKMTVARRTLRQYEPVATPFPSQHIPTRRAAAEARLAERLEHSIAEF-
MAV_5173|M.avium_104                ELHKMTVARRTLREYEPVSTPFPSAHIPTRRAEAQARLAERLEHAVAEF-
Mb0136c|M.bovis_AF2122/97           ELHKMTVARRTLREYQPVTTLFPSQHIPTRRAHAEAWLAQRLEHAIAEF-
Rv0131c|M.tuberculosis_H37Rv        ELHKMTVARRTLREYQPVTTLFPSQHIPTRRAHAEAWLAQRLEHAIAEF-
MAB_4911c|M.abscessus_ATCC_199      EVHKVTIAKEVLKDYTPYEGLFPPSHIPALTEKARAHVAARLEHRVGNL-
Mflv_2451|M.gilvum_PYR-GCK          EVHKTTVAKQVLRDHRPAEGMWPSEWIPAKREAAQAKYADFIEHEVGNL-
Mvan_4200|M.vanbaalenii_PYR-1       EVHKTTVAKQVLRDYRPAEGLWPSEWIPAKREAARAKYAEYLENEVGNL-
MSMEG_4826|M.smegmatis_MC2_155      EVHKTTVAKQVLRDYQPTEDTWPTEWIPRKREAARAKLADYLENEVGNL-
TH_3370|M.thermoresistible__bu      EVHMATVARRVLRDHAPHEGYFPTEFIPYKREAAWRKMKPVLDARPDLAA
MLBr_00737|M.leprae_Br4923          QIQRVVMSRALLR-------------------------------------
                                    :::  .:::  *:                                     

MMAR_0331|M.marinum_M               --------------
MUL_4790|M.ulcerans_Agy99           --------------
MAV_5173|M.avium_104                --------------
Mb0136c|M.bovis_AF2122/97           --------------
Rv0131c|M.tuberculosis_H37Rv        --------------
MAB_4911c|M.abscessus_ATCC_199      --------------
Mflv_2451|M.gilvum_PYR-GCK          --------------
Mvan_4200|M.vanbaalenii_PYR-1       --------------
MSMEG_4826|M.smegmatis_MC2_155      --------------
TH_3370|M.thermoresistible__bu      SAEAYQRYFAIRRR
MLBr_00737|M.leprae_Br4923          --------------

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_3370	-	-	100% (428)	putative acyl-CoA dehydrogenase
M. thermoresistible (build 8)	TH_2939	-	e-114	51.51% (431)	PUTATIVE acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)	TH_2832	-	e-104	47.95% (440)	PUTATIVE putative acyl-CoA dehydrogenase domain protein