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M. thermoresistible (build 8) TH_3136 (-)

annotation: putative acyl-CoA dehydrogenase
coordinates: 4228579 - 4229808
length: 410

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3136--100% (410)putative acyl-CoA dehydrogenase
M. thermoresistible (build 8)TH_2926-8e-4431.47% (429) PUTATIVE acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_3140-1e-4332.47% (425) PUTATIVE acyl-CoA dehydrogenase domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3164fadE230.080.44% (409) acyl-CoA dehydrogenase FADE23
M. gilvum PYR-GCKMflv_4456-0.087.53% (409) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv3140fadE230.080.44% (409) acyl-CoA dehydrogenase FADE23
M. leprae Br4923MLBr_00660fadE230.079.46% (409) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_3487-0.078.48% (409) acyl-CoA dehydrogenase
M. marinum MMMAR_1509fadE230.079.22% (409) acyl-CoA dehydrogenase FadE23
M. avium 104MAV_4019-0.081.91% (409) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155MSMEG_2080-0.089.49% (409) putative acyl-CoA dehydrogenase
M. ulcerans Agy99MUL_2432fadE231e-18078.73% (409) acyl-CoA dehydrogenase FadE23
M. vanbaalenii PYR-1Mvan_1906-0.087.78% (409) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_3136|M.thermoresistible__bu      ---MAINLELPKKLQAVVQKGHQGAAEMLRPISRKYDLQEHAYPVELDTL
Mflv_4456|M.gilvum_PYR-GCK          ---MAINLELPKKLRAVIEKGHQGAAEILRPISRKYDEKEHAYPVELDTV
MSMEG_2080|M.smegmatis_MC2_155      ---MAINLELPRKLQAVVEKGHQGAAEMLRPISRKYDLAEHAYPVELDTL
Mvan_1906|M.vanbaalenii_PYR-1       MKIMAINLEMPKKLQAVIEKGHQGAAEMIRPISRKYDLKEHAYPVELDTL
MAB_3487|M.abscessus_ATCC_1997      ---MAINLELPKKLQAIVEKGHQGAAELVRPISRKYDLAEHAYPVELETL
Mb3164|M.bovis_AF2122/97            ---MAINLELPRKLQAIIVKTHQGAAEMMRPIARKYDLKEHAYPVELDTL
Rv3140|M.tuberculosis_H37Rv         ---MAINLELPRKLQAIIVKTHQGAAEMMRPIARKYDLKEHAYPVELDTL
MMAR_1509|M.marinum_M               ---MAINLEIPRKLQAIITKTHQGTAELIRPIARKYDLKEHAYPVELDTL
MUL_2432|M.ulcerans_Agy99           ---MAINLEIPRKLQAIITKTHQGTAELIRPIARKYDLKEHAYPVELDTL
MLBr_00660|M.leprae_Br4923          ---MAINLELSRKLQAVIVKTHQGAAELMRPIARKYDLKEHTYPVELDTL
MAV_4019|M.avium_104                ---MAINLELPRKMQAVTTKTHQGAAELMRPIARKYDLKEHAYPVELDTL
                                       ******:.:*::*:  * ***:**::***:****  **:*****:*:

TH_3136|M.thermoresistible__bu      ADLFEGISEAKTISFAGAEAFAEAGKNGDKAGKKANVNGGNMSAVLNVIE
Mflv_4456|M.gilvum_PYR-GCK          ATLFEGISEAKTISFAGAEAFRDGDDD-----PKGNINGGNMSAVLNIIE
MSMEG_2080|M.smegmatis_MC2_155      ANLFEGISSAKTISFAGAEAFRDDANGSG---KDATVNGANMSALLNALE
Mvan_1906|M.vanbaalenii_PYR-1       ADIFDGITAAKTISFAGTDAFVG-ARDDG---QKSNVNGANMSALLNALE
MAB_3487|M.abscessus_ATCC_1997      ETLFAGVTAAGTFAFAGAEAFRAEENT-----AKQNVNGANMSALLNALE
Mb3164|M.bovis_AF2122/97            INLFEG--AAESFNFAGAHSLRDEDEGKD-----ENHNGANMAAVVQTME
Rv3140|M.tuberculosis_H37Rv         INLFEG--AAESFNFAGAHSLRDEDEGKD-----ENHNGANMAAVVQTME
MMAR_1509|M.marinum_M               ITLFEG--ASESYNFAGADALRGSEDSKD-----ENHNGANMAALVQTME
MUL_2432|M.ulcerans_Agy99           ITLFEG--ASESYNFAGADALRGSEDSKD-----ENHNGANMAALVQTME
MLBr_00660|M.leprae_Br4923          FNLFAG--AAESFAFAGADALGD-EDNKD-----ENHNGANMAALLQTLE
MAV_4019|M.avium_104                ISLFEG--ASESIEFAGANALGGEDEERD-----KNHNGANMAALLQTLE
                                      :* *   : :  ***:.::              . **.**:*::: :*

TH_3136|M.thermoresistible__bu      ISWGDVALMLSVPRQGLGNAAISSVATPEQLERLGKDVWAAMAITEPGFG
Mflv_4456|M.gilvum_PYR-GCK          VSWGDVALVLSIPYQGLGNAAISGVATDEQLERLGK-VWAAMAITEPGFG
MSMEG_2080|M.smegmatis_MC2_155      ISWGDVALLLSVPRQGLGNAAISSVATPEQLERLGKDVWAAMAITEPGFG
Mvan_1906|M.vanbaalenii_PYR-1       ISWGDVALLLSVPRQGLGNAAISSVATPEQLERLGKGVWAAMAITEPSFG
MAB_3487|M.abscessus_ATCC_1997      MSWGDVGLLLTVPYQGLGNAAVSSVTSKEDGDRFGK-IWAAMAITEPGFG
Mb3164|M.bovis_AF2122/97            ASWGDVAMMLSLPYQGLGNAAISAVATDEQLERLGK-VWAAMAITEPEFG
Rv3140|M.tuberculosis_H37Rv         ASWGDVAMMLSLPYQGLGNAAISAVATDEQLERLGK-VWAAMAITEPEFG
MMAR_1509|M.marinum_M               ASWADVAMMLSIPYQGLGNAAISAVATDEQLERLGK-VWAAMAITEPAFG
MUL_2432|M.ulcerans_Agy99           ASWADVAMMLSIPYQGLGNAAISAVATDEQLERLGK-VWAAMAITEPAFG
MLBr_00660|M.leprae_Br4923          ACWGDVAMLLSIPYQGLGNAAISAVATNKQLERLGK-VWAAMAITEPGFG
MAV_4019|M.avium_104                ASWGDLAMMLSVPYQGLGNAAISAVANDEQLQRLGK-VWAAMAITEPGFG
                                     .*.*:.::*::* *******:*.*:. :: :*:** :********* **

TH_3136|M.thermoresistible__bu      SDSAAVSTTATLDGDEYVINGEKIFVTAGSRASHIVVWATLDKSKGRAAI
Mflv_4456|M.gilvum_PYR-GCK          SDSAAVSTTAKLDGDEYVINGEKIYVTAGSRATHIVVWASLDKSKGRAAI
MSMEG_2080|M.smegmatis_MC2_155      SDSAAVSTTAVLDGDEYVINGEKIFVTAGSRATHIVVWATLDKSLGRAAI
Mvan_1906|M.vanbaalenii_PYR-1       SDSAAVSTTAVLDGDEYVINGEKIFVTAGSRASHIVVWATLDKSKGRAAI
MAB_3487|M.abscessus_ATCC_1997      SDSAAVSTTAKLDGDEYVINGEKIFVTAGSRATHIVVWATLDKTKGRPAI
Mb3164|M.bovis_AF2122/97            SDSAAVSTTATLDGDEYVINGEKIFVTAGSRATHIVVWATLDKSLGRPAI
Rv3140|M.tuberculosis_H37Rv         SDSAAVSTTATLDGDEYVINGEKIFVTAGSRATHIVVWATLDKSLGRPAI
MMAR_1509|M.marinum_M               SDSAAVSTTATLDGDEYVINGEKIFVTAGSRATHIVVWATLDKSKGRAAI
MUL_2432|M.ulcerans_Agy99           SDSAAVSTTATLDGDEYVINGEKIFVTAGSRATHIVVWATLDKSKGRAAI
MLBr_00660|M.leprae_Br4923          SDSAAVSTTATLDGDEYVINGEKIFVTAGSRATHIVVWATLDKSLGHAAI
MAV_4019|M.avium_104                SDSAAVSTTATLDGDEYVINGEKIFVTAGSRATHIVVWATLDKSKGRPAI
                                    ********** *************:*******:******:***: *:.**

TH_3136|M.thermoresistible__bu      KSFIVPRDHPGVTVERLEHKLGIKASDTATIRFDNVRIPKENLLGDPEIH
Mflv_4456|M.gilvum_PYR-GCK          KSFIVPREHPGVTVERLEHKLGIKASDTAAIRFDNVRIPRENLLGSPDIN
MSMEG_2080|M.smegmatis_MC2_155      KSFIVPREHPGVTVERLERKLGIKASDTAVIRFENVRIPKDNLLGDPEIH
Mvan_1906|M.vanbaalenii_PYR-1       KSFIVPREHPGVTVERLEHKLGIKASDTAVIRFDNARIPKDNLLGDPEIH
MAB_3487|M.abscessus_ATCC_1997      KSFLVPREHPGVTIERLEEKLGIKASDTAVIRFDNARIPKDYILSDPEIN
Mb3164|M.bovis_AF2122/97            KSFIVPREHPGVTVERLEHKLGIKGSDTAVIRFDNARIPKGNLLGNPEIE
Rv3140|M.tuberculosis_H37Rv         KSFIVPREHPGVTVERLEHKLGIKGSDTAVIRFDNARIPKGNLLGNPEIE
MMAR_1509|M.marinum_M               KSFIVPREHPGVIVERLEHKLGIKGSDTAVIRFDNARIPKDNLLGKPEIE
MUL_2432|M.ulcerans_Agy99           KSFIVAREHPGVIVERLEHKLGIKGSDTAVIRFDNARIPKDNLLGKPEIE
MLBr_00660|M.leprae_Br4923          KSFIVPREHPGVTVERLEYKLGIRGSDTAAIRFDNVRIPKDNLLGNPEIE
MAV_4019|M.avium_104                KSFIVPRDHPGVTVERLEKKLGIKGSDTAAIRFDNVRIPKENLLGNPEIE
                                    ***:*.*:**** :**** ****:.****.***:*.***:  :*..*:*.

TH_3136|M.thermoresistible__bu      VEKGFAGVMETFDNTRPIVAGMAVGIARAALEELRKILTDAGVEISYDKP
Mflv_4456|M.gilvum_PYR-GCK          VEKGFAGVMETFDNTRPVVAGMAVGVARAALEELRKILTDAGIEISYDKP
MSMEG_2080|M.smegmatis_MC2_155      VEKGFAGVMETFDNTRPIVAAMAVGIARAALEDLRAILTDAGVEISYDKP
Mvan_1906|M.vanbaalenii_PYR-1       VEKGFAGVMETFDNTRPIVAAMAVGVARAALEDLRKILTDAGIEISYDKP
MAB_3487|M.abscessus_ATCC_1997      TEKGFGGVMSTFDNTRPIVAAMAVGVSRASLEELRKILEDAGIEISYDRP
Mb3164|M.bovis_AF2122/97            VGKGFAGVMETFDNTRPIVAAMAVGIGRAALEEIRSVLTGAGVEISYDKP
Rv3140|M.tuberculosis_H37Rv         VGKGFAGVMETFDNTRPIVAAMAVGIGRAALEEIRSVLTGAGVEISYDKP
MMAR_1509|M.marinum_M               VGKGFSGVMETFDNTRPIVAAMAVGIGRAALEEIRKILTDAGIDIDYDRP
MUL_2432|M.ulcerans_Agy99           MGKGFSGVMETFDNTRPIVAAMAVGIGRAALEEIRKILTDAGIDIDYDRP
MLBr_00660|M.leprae_Br4923          VGKGFSGVMETFDNTRPIVAAMAVGVGRAALEEIRKILTDAGIEICYDKP
MAV_4019|M.avium_104                EGKGFSGVMETFDNTRPIVAAMAVGVARAALEEIRKILTDAGVEISYDKP
                                      ***.***.*******:**.****:.**:**::* :* .**::* **:*

TH_3136|M.thermoresistible__bu      AHAQSAPAAEFLRMEADWEAGYLLTLRAAWQADNGIPNSKEASMSKAKAA
Mflv_4456|M.gilvum_PYR-GCK          AHAQSAAAAEFLRMEADWESGYLLTLRSAWQADNRIPNSKEASMGKAKAA
MSMEG_2080|M.smegmatis_MC2_155      AHAQSAAAAEFLRMEADWEAGYLLTVRSAWQADNNIPNSKEASMGKAKAA
Mvan_1906|M.vanbaalenii_PYR-1       AHAQSAAAAEFLRMEAEWESGYLLTVRSAWQADNRIPNSKEASMGKAKAA
MAB_3487|M.abscessus_ATCC_1997      AHAQHAAAAEFLRMEADWESSYLLTLRSAWQADNNVPNSMEASMAKAKAG
Mb3164|M.bovis_AF2122/97            SHTQSAAAAEFLRMEADWEASYLLSLRAAWQADNNIPNSKEASMSKAKAG
Rv3140|M.tuberculosis_H37Rv         SHTQSAAAAEFLRMEADWEASYLLSLRAAWQADNNIPNSKEASMSKAKAG
MMAR_1509|M.marinum_M               AYTQSAAAAEFLRMEADWEASYLLSLRAAWQADNKIPNSKEASISKAKAG
MUL_2432|M.ulcerans_Agy99           AYTQSAAAAEFLRMEADWEASYLLSLRAAWQADNKIPNSKEASISKAKAG
MLBr_00660|M.leprae_Br4923          SHSQNAAAAEFLRMEADWEASYLLSLRAAWQADNNIPNSKEASMSKAKAG
MAV_4019|M.avium_104                AHVQSAAAAEFLRMEADWESAYLLSLRAAWQADNKIPNSKEASMSKAKAG
                                    :: * *.*********:**:.***::*:****** :*** ***:.****.

TH_3136|M.thermoresistible__bu      RVASDITLKAVELAGTVGYSEETLLEKWARDSKILDIFEGTQQIQLLVVA
Mflv_4456|M.gilvum_PYR-GCK          RVASDITLKTVELAGTTGYSEQALLEKWARDSKILDIFEGTQQIQQLVVA
MSMEG_2080|M.smegmatis_MC2_155      RVASDITLKAVEMAGTTGYSEQTLLEKWARDSKILDIFEGTQQIQQLVVA
Mvan_1906|M.vanbaalenii_PYR-1       RVASDITLKAVEMAGTTGYSEETLLEKWARDSKILDIFEGTQQIQQLVVA
MAB_3487|M.abscessus_ATCC_1997      RVGSDITLKAVEMAGTTGYSERTLLEKWGRDSKILDIFEGTQQIQQLVVA
Mb3164|M.bovis_AF2122/97            RMASDVTCKTVELAGTTGYSEQSLLEKWARDSKILDIFEGTQQIQQLVVA
Rv3140|M.tuberculosis_H37Rv         RMASDVTCKTVELAGTTGYSEQSLLEKWARDSKILDIFEGTQQIQQLVVA
MMAR_1509|M.marinum_M               RMASDVTLKVVELAGTTGYSEQLLLEKWGRDSKILDIFEGTQQIQQLVVA
MUL_2432|M.ulcerans_Agy99           RMASDVTLKVVELAGTTGYSEQLLLEKWGRDSKILDIFEGTQQIQQLVVA
MLBr_00660|M.leprae_Br4923          RMASDVTLKAVELAGTAGYSEKALLEKWARDSKILDIFEGTQQIQQLVVA
MAV_4019|M.avium_104                RMATDVTLKTVELAGTAGYSEQSLLEKWARDSKILDIFEGTQQIQQLVVA
                                    *:.:*:* *.**:***.****. *****.**************** ****

TH_3136|M.thermoresistible__bu      RRLLGLSSAELK
Mflv_4456|M.gilvum_PYR-GCK          RRLLGLSSAELK
MSMEG_2080|M.smegmatis_MC2_155      RRLLGLTSAELK
Mvan_1906|M.vanbaalenii_PYR-1       RRLLGLTSAQLK
MAB_3487|M.abscessus_ATCC_1997      RRLLGLSSAELK
Mb3164|M.bovis_AF2122/97            RRLLGLSSSELK
Rv3140|M.tuberculosis_H37Rv         RRLLGLSSSELK
MMAR_1509|M.marinum_M               RRLLGMSSAELK
MUL_2432|M.ulcerans_Agy99           RRLLGMSSAELK
MLBr_00660|M.leprae_Br4923          RRLLGLSSSELK
MAV_4019|M.avium_104                RRLLGLSSAELK
                                    *****::*::**