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M. marinum M MMAR_1509 (fadE23)

annotation: acyl-CoA dehydrogenase FadE23
coordinates: 1823885 - 1825090
length: 401

AINLEIPRKLQAIITKTHQGTAELIRPIARKYDLKEHAYPVELDTLITLFEGASESYNFAGADALRGSED
SKDENHNGANMAALVQTMEASWADVAMMLSIPYQGLGNAAISAVATDEQLERLGKVWAAMAITEPAFGSD
SAAVSTTATLDGDEYVINGEKIFVTAGSRATHIVVWATLDKSKGRAAIKSFIVPREHPGVIVERLEHKLG
IKGSDTAVIRFDNARIPKDNLLGKPEIEVGKGFSGVMETFDNTRPIVAAMAVGIGRAALEEIRKILTDAG
IDIDYDRPAYTQSAAAAEFLRMEADWEASYLLSLRAAWQADNKIPNSKEASISKAKAGRMASDVTLKVVE
LAGTTGYSEQLLLEKWGRDSKILDIFEGTQQIQQLVVARRLLGMSSAELK*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. marinum M MMAR_1509 fadE23 - 100% (401) acyl-CoA dehydrogenase FadE23
M. marinum M MMAR_1262 fadE25 9e-44 31.46% (391) acyl-CoA dehydrogenase FadE25
M. marinum M MMAR_0149 fadE25_2 1e-39 30.86% (418) acyl-CoA dehydrogenase FadE25_2

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3164 fadE23 0.0 89.53% (401) acyl-CoA dehydrogenase FADE23
M. gilvum PYR-GCK Mflv_4456 - 0.0 80.15% (403) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv3140 fadE23 0.0 89.53% (401) acyl-CoA dehydrogenase FADE23
M. leprae Br4923 MLBr_00660 fadE23 0.0 87.78% (401) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_3487 - 1e-178 76.43% (403) acyl-CoA dehydrogenase
M. avium 104 MAV_4019 - 0.0 87.28% (401) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_2080 - 0.0 79.56% (406) putative acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_3136 - 0.0 79.22% (409) PUTATIVE putative acyl-CoA dehydrogenase
M. ulcerans Agy99 MUL_2432 fadE23 0.0 99.50% (401) acyl-CoA dehydrogenase FadE23
M. vanbaalenii PYR-1 Mvan_1906 - 0.0 79.75% (405) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4456|M.gilvum_PYR-GCK          ---MAINLELPKKLRAVIEKGHQGAAEILRPISRKYDEKEHAYPVELDTV
TH_3136|M.thermoresistible__bu      ---MAINLELPKKLQAVVQKGHQGAAEMLRPISRKYDLQEHAYPVELDTL
MSMEG_2080|M.smegmatis_MC2_155      ---MAINLELPRKLQAVVEKGHQGAAEMLRPISRKYDLAEHAYPVELDTL
Mvan_1906|M.vanbaalenii_PYR-1       MKIMAINLEMPKKLQAVIEKGHQGAAEMIRPISRKYDLKEHAYPVELDTL
MAB_3487|M.abscessus_ATCC_1997      ---MAINLELPKKLQAIVEKGHQGAAELVRPISRKYDLAEHAYPVELETL
MMAR_1509|M.marinum_M               ---MAINLEIPRKLQAIITKTHQGTAELIRPIARKYDLKEHAYPVELDTL
MUL_2432|M.ulcerans_Agy99           ---MAINLEIPRKLQAIITKTHQGTAELIRPIARKYDLKEHAYPVELDTL
Mb3164|M.bovis_AF2122/97            ---MAINLELPRKLQAIIVKTHQGAAEMMRPIARKYDLKEHAYPVELDTL
Rv3140|M.tuberculosis_H37Rv         ---MAINLELPRKLQAIIVKTHQGAAEMMRPIARKYDLKEHAYPVELDTL
MLBr_00660|M.leprae_Br4923          ---MAINLELSRKLQAVIVKTHQGAAELMRPIARKYDLKEHTYPVELDTL
MAV_4019|M.avium_104                ---MAINLELPRKMQAVTTKTHQGAAELMRPIARKYDLKEHAYPVELDTL
                                       ******:.:*::*:  * ***:**::***:****  **:*****:*:

Mflv_4456|M.gilvum_PYR-GCK          ATLFEGISEAKTISFAGAEAFRDGDDD-----PKGNINGGNMSAVLNIIE
TH_3136|M.thermoresistible__bu      ADLFEGISEAKTISFAGAEAFAEAGKNGDKAGKKANVNGGNMSAVLNVIE
MSMEG_2080|M.smegmatis_MC2_155      ANLFEGISSAKTISFAGAEAFRDDANGSG---KDATVNGANMSALLNALE
Mvan_1906|M.vanbaalenii_PYR-1       ADIFDGITAAKTISFAGTDAFVG-ARDDG---QKSNVNGANMSALLNALE
MAB_3487|M.abscessus_ATCC_1997      ETLFAGVTAAGTFAFAGAEAFRAEENT-----AKQNVNGANMSALLNALE
MMAR_1509|M.marinum_M               ITLFEG--ASESYNFAGADALRGSEDSKD-----ENHNGANMAALVQTME
MUL_2432|M.ulcerans_Agy99           ITLFEG--ASESYNFAGADALRGSEDSKD-----ENHNGANMAALVQTME
Mb3164|M.bovis_AF2122/97            INLFEG--AAESFNFAGAHSLRDEDEGKD-----ENHNGANMAAVVQTME
Rv3140|M.tuberculosis_H37Rv         INLFEG--AAESFNFAGAHSLRDEDEGKD-----ENHNGANMAAVVQTME
MLBr_00660|M.leprae_Br4923          FNLFAG--AAESFAFAGADALGD-EDNKD-----ENHNGANMAALLQTLE
MAV_4019|M.avium_104                ISLFEG--ASESIEFAGANALGGEDEERD-----KNHNGANMAALLQTLE
                                      :* *   : :  ***:.::              . **.**:*::: :*

Mflv_4456|M.gilvum_PYR-GCK          VSWGDVALVLSIPYQGLGNAAISGVATDEQLERLGK-VWAAMAITEPGFG
TH_3136|M.thermoresistible__bu      ISWGDVALMLSVPRQGLGNAAISSVATPEQLERLGKDVWAAMAITEPGFG
MSMEG_2080|M.smegmatis_MC2_155      ISWGDVALLLSVPRQGLGNAAISSVATPEQLERLGKDVWAAMAITEPGFG
Mvan_1906|M.vanbaalenii_PYR-1       ISWGDVALLLSVPRQGLGNAAISSVATPEQLERLGKGVWAAMAITEPSFG
MAB_3487|M.abscessus_ATCC_1997      MSWGDVGLLLTVPYQGLGNAAVSSVTSKEDGDRFGK-IWAAMAITEPGFG
MMAR_1509|M.marinum_M               ASWADVAMMLSIPYQGLGNAAISAVATDEQLERLGK-VWAAMAITEPAFG
MUL_2432|M.ulcerans_Agy99           ASWADVAMMLSIPYQGLGNAAISAVATDEQLERLGK-VWAAMAITEPAFG
Mb3164|M.bovis_AF2122/97            ASWGDVAMMLSLPYQGLGNAAISAVATDEQLERLGK-VWAAMAITEPEFG
Rv3140|M.tuberculosis_H37Rv         ASWGDVAMMLSLPYQGLGNAAISAVATDEQLERLGK-VWAAMAITEPEFG
MLBr_00660|M.leprae_Br4923          ACWGDVAMLLSIPYQGLGNAAISAVATNKQLERLGK-VWAAMAITEPGFG
MAV_4019|M.avium_104                ASWGDLAMMLSVPYQGLGNAAISAVANDEQLQRLGK-VWAAMAITEPGFG
                                     .*.*:.::*::* *******:*.*:. :: :*:** :********* **

Mflv_4456|M.gilvum_PYR-GCK          SDSAAVSTTAKLDGDEYVINGEKIYVTAGSRATHIVVWASLDKSKGRAAI
TH_3136|M.thermoresistible__bu      SDSAAVSTTATLDGDEYVINGEKIFVTAGSRASHIVVWATLDKSKGRAAI
MSMEG_2080|M.smegmatis_MC2_155      SDSAAVSTTAVLDGDEYVINGEKIFVTAGSRATHIVVWATLDKSLGRAAI
Mvan_1906|M.vanbaalenii_PYR-1       SDSAAVSTTAVLDGDEYVINGEKIFVTAGSRASHIVVWATLDKSKGRAAI
MAB_3487|M.abscessus_ATCC_1997      SDSAAVSTTAKLDGDEYVINGEKIFVTAGSRATHIVVWATLDKTKGRPAI
MMAR_1509|M.marinum_M               SDSAAVSTTATLDGDEYVINGEKIFVTAGSRATHIVVWATLDKSKGRAAI
MUL_2432|M.ulcerans_Agy99           SDSAAVSTTATLDGDEYVINGEKIFVTAGSRATHIVVWATLDKSKGRAAI
Mb3164|M.bovis_AF2122/97            SDSAAVSTTATLDGDEYVINGEKIFVTAGSRATHIVVWATLDKSLGRPAI
Rv3140|M.tuberculosis_H37Rv         SDSAAVSTTATLDGDEYVINGEKIFVTAGSRATHIVVWATLDKSLGRPAI
MLBr_00660|M.leprae_Br4923          SDSAAVSTTATLDGDEYVINGEKIFVTAGSRATHIVVWATLDKSLGHAAI
MAV_4019|M.avium_104                SDSAAVSTTATLDGDEYVINGEKIFVTAGSRATHIVVWATLDKSKGRPAI
                                    ********** *************:*******:******:***: *:.**

Mflv_4456|M.gilvum_PYR-GCK          KSFIVPREHPGVTVERLEHKLGIKASDTAAIRFDNVRIPRENLLGSPDIN
TH_3136|M.thermoresistible__bu      KSFIVPRDHPGVTVERLEHKLGIKASDTATIRFDNVRIPKENLLGDPEIH
MSMEG_2080|M.smegmatis_MC2_155      KSFIVPREHPGVTVERLERKLGIKASDTAVIRFENVRIPKDNLLGDPEIH
Mvan_1906|M.vanbaalenii_PYR-1       KSFIVPREHPGVTVERLEHKLGIKASDTAVIRFDNARIPKDNLLGDPEIH
MAB_3487|M.abscessus_ATCC_1997      KSFLVPREHPGVTIERLEEKLGIKASDTAVIRFDNARIPKDYILSDPEIN
MMAR_1509|M.marinum_M               KSFIVPREHPGVIVERLEHKLGIKGSDTAVIRFDNARIPKDNLLGKPEIE
MUL_2432|M.ulcerans_Agy99           KSFIVAREHPGVIVERLEHKLGIKGSDTAVIRFDNARIPKDNLLGKPEIE
Mb3164|M.bovis_AF2122/97            KSFIVPREHPGVTVERLEHKLGIKGSDTAVIRFDNARIPKGNLLGNPEIE
Rv3140|M.tuberculosis_H37Rv         KSFIVPREHPGVTVERLEHKLGIKGSDTAVIRFDNARIPKGNLLGNPEIE
MLBr_00660|M.leprae_Br4923          KSFIVPREHPGVTVERLEYKLGIRGSDTAAIRFDNVRIPKDNLLGNPEIE
MAV_4019|M.avium_104                KSFIVPRDHPGVTVERLEKKLGIKGSDTAAIRFDNVRIPKENLLGNPEIE
                                    ***:*.*:**** :**** ****:.****.***:*.***:  :*..*:*.

Mflv_4456|M.gilvum_PYR-GCK          VEKGFAGVMETFDNTRPVVAGMAVGVARAALEELRKILTDAGIEISYDKP
TH_3136|M.thermoresistible__bu      VEKGFAGVMETFDNTRPIVAGMAVGIARAALEELRKILTDAGVEISYDKP
MSMEG_2080|M.smegmatis_MC2_155      VEKGFAGVMETFDNTRPIVAAMAVGIARAALEDLRAILTDAGVEISYDKP
Mvan_1906|M.vanbaalenii_PYR-1       VEKGFAGVMETFDNTRPIVAAMAVGVARAALEDLRKILTDAGIEISYDKP
MAB_3487|M.abscessus_ATCC_1997      TEKGFGGVMSTFDNTRPIVAAMAVGVSRASLEELRKILEDAGIEISYDRP
MMAR_1509|M.marinum_M               VGKGFSGVMETFDNTRPIVAAMAVGIGRAALEEIRKILTDAGIDIDYDRP
MUL_2432|M.ulcerans_Agy99           MGKGFSGVMETFDNTRPIVAAMAVGIGRAALEEIRKILTDAGIDIDYDRP
Mb3164|M.bovis_AF2122/97            VGKGFAGVMETFDNTRPIVAAMAVGIGRAALEEIRSVLTGAGVEISYDKP
Rv3140|M.tuberculosis_H37Rv         VGKGFAGVMETFDNTRPIVAAMAVGIGRAALEEIRSVLTGAGVEISYDKP
MLBr_00660|M.leprae_Br4923          VGKGFSGVMETFDNTRPIVAAMAVGVGRAALEEIRKILTDAGIEICYDKP
MAV_4019|M.avium_104                EGKGFSGVMETFDNTRPIVAAMAVGVARAALEEIRKILTDAGVEISYDKP
                                      ***.***.*******:**.****:.**:**::* :* .**::* **:*

Mflv_4456|M.gilvum_PYR-GCK          AHAQSAAAAEFLRMEADWESGYLLTLRSAWQADNRIPNSKEASMGKAKAA
TH_3136|M.thermoresistible__bu      AHAQSAPAAEFLRMEADWEAGYLLTLRAAWQADNGIPNSKEASMSKAKAA
MSMEG_2080|M.smegmatis_MC2_155      AHAQSAAAAEFLRMEADWEAGYLLTVRSAWQADNNIPNSKEASMGKAKAA
Mvan_1906|M.vanbaalenii_PYR-1       AHAQSAAAAEFLRMEAEWESGYLLTVRSAWQADNRIPNSKEASMGKAKAA
MAB_3487|M.abscessus_ATCC_1997      AHAQHAAAAEFLRMEADWESSYLLTLRSAWQADNNVPNSMEASMAKAKAG
MMAR_1509|M.marinum_M               AYTQSAAAAEFLRMEADWEASYLLSLRAAWQADNKIPNSKEASISKAKAG
MUL_2432|M.ulcerans_Agy99           AYTQSAAAAEFLRMEADWEASYLLSLRAAWQADNKIPNSKEASISKAKAG
Mb3164|M.bovis_AF2122/97            SHTQSAAAAEFLRMEADWEASYLLSLRAAWQADNNIPNSKEASMSKAKAG
Rv3140|M.tuberculosis_H37Rv         SHTQSAAAAEFLRMEADWEASYLLSLRAAWQADNNIPNSKEASMSKAKAG
MLBr_00660|M.leprae_Br4923          SHSQNAAAAEFLRMEADWEASYLLSLRAAWQADNNIPNSKEASMSKAKAG
MAV_4019|M.avium_104                AHVQSAAAAEFLRMEADWESAYLLSLRAAWQADNKIPNSKEASMSKAKAG
                                    :: * *.*********:**:.***::*:****** :*** ***:.****.

Mflv_4456|M.gilvum_PYR-GCK          RVASDITLKTVELAGTTGYSEQALLEKWARDSKILDIFEGTQQIQQLVVA
TH_3136|M.thermoresistible__bu      RVASDITLKAVELAGTVGYSEETLLEKWARDSKILDIFEGTQQIQLLVVA
MSMEG_2080|M.smegmatis_MC2_155      RVASDITLKAVEMAGTTGYSEQTLLEKWARDSKILDIFEGTQQIQQLVVA
Mvan_1906|M.vanbaalenii_PYR-1       RVASDITLKAVEMAGTTGYSEETLLEKWARDSKILDIFEGTQQIQQLVVA
MAB_3487|M.abscessus_ATCC_1997      RVGSDITLKAVEMAGTTGYSERTLLEKWGRDSKILDIFEGTQQIQQLVVA
MMAR_1509|M.marinum_M               RMASDVTLKVVELAGTTGYSEQLLLEKWGRDSKILDIFEGTQQIQQLVVA
MUL_2432|M.ulcerans_Agy99           RMASDVTLKVVELAGTTGYSEQLLLEKWGRDSKILDIFEGTQQIQQLVVA
Mb3164|M.bovis_AF2122/97            RMASDVTCKTVELAGTTGYSEQSLLEKWARDSKILDIFEGTQQIQQLVVA
Rv3140|M.tuberculosis_H37Rv         RMASDVTCKTVELAGTTGYSEQSLLEKWARDSKILDIFEGTQQIQQLVVA
MLBr_00660|M.leprae_Br4923          RMASDVTLKAVELAGTAGYSEKALLEKWARDSKILDIFEGTQQIQQLVVA
MAV_4019|M.avium_104                RMATDVTLKTVELAGTAGYSEQSLLEKWARDSKILDIFEGTQQIQQLVVA
                                    *:.:*:* *.**:***.****. *****.**************** ****

Mflv_4456|M.gilvum_PYR-GCK          RRLLGLSSAELK
TH_3136|M.thermoresistible__bu      RRLLGLSSAELK
MSMEG_2080|M.smegmatis_MC2_155      RRLLGLTSAELK
Mvan_1906|M.vanbaalenii_PYR-1       RRLLGLTSAQLK
MAB_3487|M.abscessus_ATCC_1997      RRLLGLSSAELK
MMAR_1509|M.marinum_M               RRLLGMSSAELK
MUL_2432|M.ulcerans_Agy99           RRLLGMSSAELK
Mb3164|M.bovis_AF2122/97            RRLLGLSSSELK
Rv3140|M.tuberculosis_H37Rv         RRLLGLSSSELK
MLBr_00660|M.leprae_Br4923          RRLLGLSSSELK
MAV_4019|M.avium_104                RRLLGLSSAELK
                                    *****::*::**

species	id	gene	e-value	identity (len)	annotation
M. marinum M	MMAR_1509	fadE23	-	100% (401)	acyl-CoA dehydrogenase FadE23
M. marinum M	MMAR_1262	fadE25	9e-44	31.46% (391)	acyl-CoA dehydrogenase FadE25
M. marinum M	MMAR_0149	fadE25_2	1e-39	30.86% (418)	acyl-CoA dehydrogenase FadE25_2