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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2455 | - | - | 100% (354) | - |
| M. thermoresistible (build 8) | TH_3579 | - | 4e-64 | 40.68% (322) | PUTATIVE - |
| M. thermoresistible (build 8) | TH_2332 | - | 6e-10 | 29.22% (219) | POSIBLE GLYOXALASE II (HYDROXYACYLGLUTATHIONE HYDROLASE) (GLX |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2612c | - | 4e-12 | 30.77% (234) | glyoxalase II |
| M. gilvum PYR-GCK | Mflv_3810 | - | 5e-14 | 32.74% (223) | beta-lactamase domain-containing protein |
| M. tuberculosis H37Rv | Rv2581c | - | 4e-12 | 30.77% (234) | glyoxalase II |
| M. leprae Br4923 | MLBr_00493 | - | 1e-09 | 32.16% (227) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_1114 | - | 2e-13 | 33.16% (196) | metallo-beta-lactamase superfamily |
| M. marinum M | MMAR_2126 | - | 3e-10 | 32.74% (223) | Zn-dependent glyoxylase |
| M. avium 104 | MAV_3461 | - | 1e-10 | 32.17% (230) | metallo-beta-lactamase family protein |
| M. smegmatis MC2 155 | MSMEG_6278 | - | 2e-12 | 34.69% (196) | metallo-beta-lactamase superfamily protein, putative |
| M. ulcerans Agy99 | MUL_1731 | - | 3e-10 | 32.74% (223) | Zn-dependent glyoxylase |
| M. vanbaalenii PYR-1 | Mvan_2589 | - | 2e-13 | 32.27% (220) | beta-lactamase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2612c|M.bovis_AF2122/97 -------------------------------MLITGFPAG---LLACNCY
Rv2581c|M.tuberculosis_H37Rv -------------------------------MLITGFPAG---LLACNCY
MMAR_2126|M.marinum_M -------------------------------MLITGFPAG---VLQCNCY
MUL_1731|M.ulcerans_Agy99 -------------------------------MLITGFPAG---VLQCNCY
MAV_3461|M.avium_104 -------------------------------MLITGFPAG---MLACNCY
MLBr_00493|M.leprae_Br4923 -------------------------------MLITGFPAG---MLQCNCY
Mflv_3810|M.gilvum_PYR-GCK -------------------------------MLITGFPAG---LLACNCY
Mvan_2589|M.vanbaalenii_PYR-1 -------------------------------MLITGFPAG---MLACNCY
MAB_1114|M.abscessus_ATCC_1997 -------------------MSSPDLQQLAPSLFRLRIPGGR--AHLLNCY
MSMEG_6278|M.smegmatis_MC2_155 ---------------------MPDLLKIADSLYRLRIPGDR--AHLLNCY
TH_2455|M.thermoresistible__bu LTTELSVSIDSPDLGAATGSDTADLQRIAPRVVRAAIPLPLPDLKVINAY
: :* *.*
Mb2612c|M.bovis_AF2122/97 VLAERPGTDAVIVDP----GQGAMGTLRRILDKNRLTPAAVLLTHGHIDH
Rv2581c|M.tuberculosis_H37Rv VLAERPGTDAVIVDP----GQGAMGTLRRILDKNRLTPAAVLLTHGHIDH
MMAR_2126|M.marinum_M VLAERPGTDAIIVDP----GQRAMGQLRRILDKNRLTPAAVLITHGHIDH
MUL_1731|M.ulcerans_Agy99 ALAERPGTDAIIVDP----GQRAMGQLRRILDKNRLTPAAVLITHGHIDH
MAV_3461|M.avium_104 VLAQRPGTDAVIVDP----GQRAMGPLRRILDRHRLTPAAVLLTHGHIDH
MLBr_00493|M.leprae_Br4923 VLADRAGTDAVIVDP----GQRAMGPLRRILDENRLTPSAVLLTHGHIDH
Mflv_3810|M.gilvum_PYR-GCK VLAPRQGADAIVVDP----GQRAMGSLARILDENRLTPAAVLLTHGHIDH
Mvan_2589|M.vanbaalenii_PYR-1 VLALRQGADAIVVDP----GQRAMGPLRQILDDNRLTPAAVLLTHGHIDH
MAB_1114|M.abscessus_ATCC_1997 LWLAPDGVTLIDTGWP--DSAELIEQALHQLGRGRTDIVRIVLTHFHEDH
MSMEG_6278|M.smegmatis_MC2_155 LWQEPDGVTLIDTGWP--GEAGLIAEALAMLGLRRLHVKRVVLTHFHEDH
TH_2455|M.thermoresistible__bu LVAGDDGVTLIDPGWACAESEEKLLAALDTLGYTRSDVRRILATHAHWDH
*. : . : *. * :: ** * **
Mb2612c|M.bovis_AF2122/97 IWSAQKVSDTFGCPTYVHPADRFMLT--DPIYGLGP----RIAQLVAGAF
Rv2581c|M.tuberculosis_H37Rv IWSAQKVSDTFGCPTYVHPADRFMLT--DPIYGLGP----RIAQLVAGAF
MMAR_2126|M.marinum_M MWSAQKVSDTFGCPTYIHPEDRFMLK--DPIYGLGP----RVAQLFAGAF
MUL_1731|M.ulcerans_Agy99 MWSAQKVSDTFGCPTYIHPEDRFMLK--DPIYGLGP----RVAQLFAGAF
MAV_3461|M.avium_104 IWSAQKVSDTYGCPTYIHPEDRFMLK--DPIYGLGP----RLAQLAAGAF
MLBr_00493|M.leprae_Br4923 MWSAQKVSDTYGCPTYIHPEDRFMLT--DPLFGFGP----RVAQVVTGAF
Mflv_3810|M.gilvum_PYR-GCK MWSAQKVADTYGCPTFVHPADRHMLT--DPIAGLGQGFLAGLGRLALSPV
Mvan_2589|M.vanbaalenii_PYR-1 MWSAQKVADTYGCPTFIHPADRHMLA--DPIKGFGRGFLGGLARSAVGAM
MAB_1114|M.abscessus_ATCC_1997 VGAAAEIAAWSRAEVIAGEPDSPFIT--GERGGPVP--VLTAGEQALHPG
MSMEG_6278|M.smegmatis_MC2_155 TGAAAEIADWADVEVIAGAADAPFIR--GDEPGPLP--VLTDAERTLRSD
TH_2455|M.thermoresistible__bu YSLAVKWRHELGVELALGSGERHSISSFDPDRGLHPAQVGMLTRAGAPEL
* : : : . * .
Mb2612c|M.bovis_AF2122/97 FREPKQ--------------VVELDRDGDKIDLGGISVNIDHTPGHTRGS
Rv2581c|M.tuberculosis_H37Rv FREPKQ--------------VVELDRDGDKIDLGGISVNIDHTPGHTRGS
MMAR_2126|M.marinum_M FREPKQ--------------VVELDRDGDKIDLGNICVNVDHTPGHTRGS
MUL_1731|M.ulcerans_Agy99 FREPKQ--------------VVELDRDGDKIDLGNICVNVDHTPGHTRGS
MAV_3461|M.avium_104 FREPRQ--------------VVELDRDGDKLDLGSVTVNVDHTPGHTRGS
MLBr_00493|M.leprae_Br4923 FREPKQ--------------VVELDRDGDKLDLGSVTVNVDHTPGHTRGS
Mflv_3810|M.gilvum_PYR-GCK FREPRQ--------------VLELDRDGDKIELGGITVTVDHTPGHTKGS
Mvan_2589|M.vanbaalenii_PYR-1 FREPRQ--------------VLELDRDGDKIELGGITVAVDHTPGHTQGS
MAB_1114|M.abscessus_ATCC_1997 FTEPPHGPVC---------RVDRAVKDGEVLDFAGG-AHVIAVPGHTPGS
MSMEG_6278|M.smegmatis_MC2_155 LTEPPVGPPC---------RVDTTVRDGDVLDFAGG-ARVVGAPGHTPGS
TH_2455|M.thermoresistible__bu ARQVRRLKWQPYERDVAFTPPDRWLEDGDRIDCGGITLTVRSTPGHTRGH
: .**: :: .. : .**** *
Mb2612c|M.bovis_AF2122/97 VVFRVLQATNNDKDIVFTGDTLFERAIGRTDLAGGSGRDLLRSIVD--KL
Rv2581c|M.tuberculosis_H37Rv VVFRVLQATNNDKDIVFTGDTLFERAIGRTDLAGGSGRDLLRSIVD--KL
MMAR_2126|M.marinum_M VCFRVPQAAKDDRDVVFTGDTLFERSIGRSDLFGGSGRDLLRSIVD--KL
MUL_1731|M.ulcerans_Agy99 VCFRVPQAAKDDRDVVFTGDTLFERSIGRSDLFGGSGRDLLRSIVD--KL
MAV_3461|M.avium_104 MCFRVS----SDKQVVFTGDTLFERSVGRTDLFGGSGRDLLTSIVD--KL
MLBr_00493|M.leprae_Br4923 VCFWVA----ADTDVVLTGDTLFERTIGRTDLFGGSGRDLYRSIVE--KL
Mflv_3810|M.gilvum_PYR-GCK VVFRVEQ---GPDQVAFTGDTLFRASVGRTDLPGGSGRDLLESIVT--KL
Mvan_2589|M.vanbaalenii_PYR-1 VVFRVEQ---GTEPVAFTGDTLFRSSVGRTDLPGGSGRDLMESLVT--KL
MAB_1114|M.abscessus_ATCC_1997 IALYLP-----AADAVLTGDAVAEFNGQVILGVFNSDRQVAARSLS--RL
MSMEG_6278|M.smegmatis_MC2_155 IGLYLP-----AADAVLTGDAVAEFNGHVIVGVFNVDRAAAVASVQ--RL
TH_2455|M.thermoresistible__bu VVFADE-----ANRLMFTGDHLLPRITPSIGFEDSPEPLPLRSFLSSLRL
: : :*** : . : :*
Mb2612c|M.bovis_AF2122/97 LVLDDSTVVLPGHGNS---TTIGAERRFNPFLEGLSR-------------
Rv2581c|M.tuberculosis_H37Rv LVLDDSTVVLPGHGNS---TTIGAERRFNPFLEGLSR-------------
MMAR_2126|M.marinum_M LVLDDKTVVLPGHGNS---TSIGAERRFNPFLEGLST-------------
MUL_1731|M.ulcerans_Agy99 LVLDDKTVVLPGHGNS---TSIGAERRFNPFLEGLST-------------
MAV_3461|M.avium_104 LVLDDDTVVLPGHGNA---TTIGAERRLNPFLEGL---------------
MLBr_00493|M.leprae_Br4923 LVLDDKTVVLPGHGNS---TTIGAERRFNPFLEGL---------------
Mflv_3810|M.gilvum_PYR-GCK LVLDDDTLVLPGHGAR---STIGVERHTNPFLEGLKP-------------
Mvan_2589|M.vanbaalenii_PYR-1 LVLDDDTLVLPGHGER---STIGIERHTNPFLEGLTP-------------
MAB_1114|M.abscessus_ATCC_1997 AATGAEIGGF-GHGEA---ILEKASARIATAIDAFGE-------------
MSMEG_6278|M.smegmatis_MC2_155 AETGAQVAGF-GHGEV---LLTDAAARIADAADPFA--------------
TH_2455|M.thermoresistible__bu VLDLPEHRMLPAHGGADRTTTVRAAELIEHHRDRLALVADLVAARGQATA
. : .** : :
Mb2612c|M.bovis_AF2122/97 --------------------------------------------------
Rv2581c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2126|M.marinum_M --------------------------------------------------
MUL_1731|M.ulcerans_Agy99 --------------------------------------------------
MAV_3461|M.avium_104 --------------------------------------------------
MLBr_00493|M.leprae_Br4923 --------------------------------------------------
Mflv_3810|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2589|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1114|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6278|M.smegmatis_MC2_155 --------------------------------------------------
TH_2455|M.thermoresistible__bu YEIATRMRWTRHDRPITDLDPIHRMVAVIEVMSHLDLLVHQGTLAEDTSH
Mb2612c|M.bovis_AF2122/97 --------
Rv2581c|M.tuberculosis_H37Rv --------
MMAR_2126|M.marinum_M --------
MUL_1731|M.ulcerans_Agy99 --------
MAV_3461|M.avium_104 --------
MLBr_00493|M.leprae_Br4923 --------
Mflv_3810|M.gilvum_PYR-GCK --------
Mvan_2589|M.vanbaalenii_PYR-1 --------
MAB_1114|M.abscessus_ATCC_1997 --------
MSMEG_6278|M.smegmatis_MC2_155 --------
TH_2455|M.thermoresistible__bu PASVFQPA