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M. thermoresistible (build 8) TH_2387 (trmD)

annotation: PROBABLE TRNA (GUANINE-N1)-METHYLTRANSFERASE TRMD (M1G-METHYLTRANSFERASE) (TRNA
coordinates: 4670799 - 4671515
length: 239

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2387trmD-100% (239)PROBABLE TRNA (GUANINE-N1)-METHYLTRANSFERASE TRMD (M1G-METHYLTRANSFERASE) (TRNA

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2930ctrmD1e-11082.30% (226) tRNA (guanine-N(1)-)-methyltransferase
M. gilvum PYR-GCKMflv_4172trmD1e-10880.62% (227) tRNA (guanine-N(1)-)-methyltransferase
M. tuberculosis H37RvRv2906ctrmD1e-11082.30% (226) tRNA (guanine-N(1)-)-methyltransferase
M. leprae Br4923MLBr_01615trmD1e-10778.76% (226) tRNA (guanine-N(1)-)-methyltransferase
M. abscessus ATCC 19977MAB_3226c-1e-10275.00% (236) tRNA (guanine-N(1)-)-methyltransferase (TrmD)
M. marinum MMMAR_1802trmD1e-10678.26% (230) tRNA (guanine-N1)-methyltransferase TrmD
M. avium 104MAV_3760trmD1e-10878.90% (237) tRNA (guanine-N(1)-)-methyltransferase
M. smegmatis MC2 155MSMEG_2438trmD1e-11384.65% (228) tRNA (guanine-N(1)-)-methyltransferase
M. ulcerans Agy99MUL_2050trmD1e-10778.70% (230) tRNA (guanine-N(1)-)-methyltransferase
M. vanbaalenii PYR-1Mvan_2190trmD1e-11183.33% (228) tRNA (guanine-N(1)-)-methyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


TH_2387|M.thermoresistible__bu      VRIDVITIFPRYLDPLRESLPGKAIEAGIVDLRVHDLRRWTHDVHRSVDD
MSMEG_2438|M.smegmatis_MC2_155      MRIDVISIFPAYLDPIRQSLPGKAIDAGIVSVEVHDLRNWTHDVHRSVDD
MMAR_1802|M.marinum_M               MKIDVVTIFPAYLDPLRQSLPGRAIASGLVDLQVHDLRRWTYDVHHSVDD
MUL_2050|M.ulcerans_Agy99           MKIDVVTIFPAYLDPLRQSLPGRAIASGLVDLQVHDLRRWTYDVHHSVDD
MAV_3760|M.avium_104                MRIDVVTIFPAYLDPLRQSLPGKAIQSGLVDLRVHDLRRWTHDVHRSVDD
Mb2930c|M.bovis_AF2122/97           MRIDIVTIFPACLDPLRQSLPGKAIESGLVDLNVHDLRRWTHDVHHSVDD
Rv2906c|M.tuberculosis_H37Rv        MRIDIVTIFPACLDPLRQSLPGKAIESGLVDLNVHDLRRWTHDVHHSVDD
MLBr_01615|M.leprae_Br4923          MKIDIVTIFPAYLDPLRQSLPGKAIESGLVDVQVHDLRRWTHDVHHSVDD
Mflv_4172|M.gilvum_PYR-GCK          MRIDVVTIFPAFLDALRQALPGKAIEAGIIDLAVHDLRDWTHDVHRSVDD
Mvan_2190|M.vanbaalenii_PYR-1       MRIDVVTIFPAFLDALRQALPGKAIEAGIVALAVHDLRDWTHDVHRSVDD
MAB_3226c|M.abscessus_ATCC_199      MKIDVVTIFPEYLQPVRQSLPGKAIDAGLVDVAVHDLRRWTHDVHKSVDD
                                    ::**:::***  *:.:*::***:** :*:: : ***** **:***:****

TH_2387|M.thermoresistible__bu      TPYGGGPGMVMTAPVWGEALDEICTEQTLLVVPTPAGRLFTQNVAQRWAG
MSMEG_2438|M.smegmatis_MC2_155      SPYGGGPGMVMKAPVWGEALDEICSEETLLVVPTPAGRLFDQRTAQRWST
MMAR_1802|M.marinum_M               SPYGGGPGMVMKAPVWGEALDEICSAETLLVVPTPAGSLFDQATARRWSA
MUL_2050|M.ulcerans_Agy99           SPYGGGPGMVMKAPVWGEALDEICSAETLLVVPTPAGSLFDQATAQRWSA
MAV_3760|M.avium_104                APYGGGPGMVMKAPVWGEALDEIASAETLLVVPTPAGALFDQATAARWSA
Mb2930c|M.bovis_AF2122/97           APYGGGPGMVMKAPVWGEALDEICSSETLLIVPTPAGVLFTQATAQRWTT
Rv2906c|M.tuberculosis_H37Rv        APYGGGPGMVMKAPVWGEALDEICSSETLLIVPTPAGVLFTQATAQRWTT
MLBr_01615|M.leprae_Br4923          VPYGGGPGMVMKAPVWGEALDEICFDETLLVIPTPAGALFTQATAQCWST
Mflv_4172|M.gilvum_PYR-GCK          SPYGGGPGMVMKAPVWGAALDEICSPETLLVVPSPAGRLFTQATAQRWST
Mvan_2190|M.vanbaalenii_PYR-1       SPYGGGPGMVMKAPIWGAALDEICSPETLLVVPSPAGRLFTQATAQRWSG
MAB_3226c|M.abscessus_ATCC_199      SPYGGGPGMVMKPTVWGDALDEICTSETLLVVPTPAGYPFTQETAWQWST
                                     **********...:** *****.  :***::*:***  * * .*  *: 

TH_2387|M.thermoresistible__bu      ESHLVFACGRYEGIDQRVIDDAARRMRVEEVSIGDYVLAGGEAAALVMIE
MSMEG_2438|M.smegmatis_MC2_155      ERHLVFACGRYEGIDQRVVDDAARRMRVEEVSIGDYVLNGGEAATLVMVE
MMAR_1802|M.marinum_M               EQHLVFACGRYEGIDQRVAEDSARRMRVEEVSIGDYVLPGGESAAVVMIE
MUL_2050|M.ulcerans_Agy99           EQHLVFACGRYEGIDQRVAEDSARRMRVEEVSIGDYVLPGGESAAVVMIE
MAV_3760|M.avium_104                ERHLVFACGRYEGIDQRVVEDAARRMRVEEVSIGDYVLPGGESAAVVMIE
Mb2930c|M.bovis_AF2122/97           ESHLVFACGRYEGIDQRVVQDAARRMRVEEVSIGDYVLPGGESAAVVMVE
Rv2906c|M.tuberculosis_H37Rv        ESHLVFACGRYEGIDQRVVQDAARRMRVEEVSIGDYVLPGGESAAVVMVE
MLBr_01615|M.leprae_Br4923          ERHLVFACGRYEGIDQRVVDDAVRRMRVEEVSIGDYVLPGGESAAVVMIE
Mflv_4172|M.gilvum_PYR-GCK          ERHLVFACGRYEGIDQRVVEDAATRMRVEEVSLGDYVLPGGESAAVVMVE
Mvan_2190|M.vanbaalenii_PYR-1       EEHLVFACGRYEGIDQRVIDDAARRMRVEEVSIGDYVLPGGESAAVVMIE
MAB_3226c|M.abscessus_ATCC_199      EDHLVIACGRYEGIDQRVADDAATRMRVREVSIGDYVLNGGEAAALVIIE
                                    * ***:************ :*:. ****.***:***** ***:*::*::*

TH_2387|M.thermoresistible__bu      AVVRLLPGVMGNPASHQEDSHSGRYRGLLEGPSYTRPPSWRGLDVPEVLL
MSMEG_2438|M.smegmatis_MC2_155      AVVRLLPDVLGNPASHQQDSHS---DGLLEGPSYTRPPSWRGLDVPPVLL
MMAR_1802|M.marinum_M               AVLRLLTGVLGNPASHQEDSFSPELDRLLEGPSYTRPPSWRGLDVPEILL
MUL_2050|M.ulcerans_Agy99           AVLRLLTGVLGNPASHQEDSFSPELDRLLEGPSYTRPPSWRGLDVPEILL
MAV_3760|M.avium_104                AVLRLLDGVLGNPASRHDDSHSPALDRRLEGPSYTRPPSWRGLDVPEVLL
Mb2930c|M.bovis_AF2122/97           AVLRLLAGVLGNPASHQDDSHSTGLDGLLEGPSYTRPASWRGLDVPEVLL
Rv2906c|M.tuberculosis_H37Rv        AVLRLLAGVLGNPASHQDDSHSTGLDGLLEGPSYTRPASWRGLDVPEVLL
MLBr_01615|M.leprae_Br4923          AVLRLVAGVLGNPASHRDDSHSPDLGRLLEGPSYTRPPTWRGLDVPPVLL
Mflv_4172|M.gilvum_PYR-GCK          AVVRLLPDVLGNPASHQDDSHSEFVGGLLEGPSYTRPASWRGLDVPDVLL
Mvan_2190|M.vanbaalenii_PYR-1       AVVRLLPDVLGNPASHQDDSHSELVGGLLEGPSYTRPASWRGLDVPDVLL
MAB_3226c|M.abscessus_ATCC_199      AVLRLVPGVLGNALSAQEDSHSEGMASLLEGPSYTRPPSWRGMDVPPVLL
                                    **:**: .*:**. * ::**.*      *********.:***:*** :**

TH_2387|M.thermoresistible__bu      SGNHAKIAAWRREQALKRTRERRPDLLDSEGDPPGEQA----
MSMEG_2438|M.smegmatis_MC2_155      SGDHAKVAAWRHEQALQRTRERRPDLLD--------------
MMAR_1802|M.marinum_M               SGDHARIATWRREVSLRRTRERRPDLAP----PE--------
MUL_2050|M.ulcerans_Agy99           SGDHARIATWRREVSLRRTRERRPDLAP----PE--------
MAV_3760|M.avium_104                SGDHARIAAWRREVSLQRTRERRPELLADPVGPQDGPGL---
Mb2930c|M.bovis_AF2122/97           SGDHARIAAWRREVSLQRTRERRPDLSH----PD--------
Rv2906c|M.tuberculosis_H37Rv        SGDHARIAAWRREVSLQRTRERRPDLSH----PD--------
MLBr_01615|M.leprae_Br4923          SGDHARIAAWRREASLRRTRKRRPDLSG----ARFVWGLGLS
Mflv_4172|M.gilvum_PYR-GCK          SGDHARIAAWRHQQGLERTRERRPDLLP----PDAS------
Mvan_2190|M.vanbaalenii_PYR-1       SGDHARIAAWRREQGLQRTRERRPDLLD--------------
MAB_3226c|M.abscessus_ATCC_199      SGDHAKIAAWRAEQSRQRTIERRPDLLGFDSPTGEHGGDGLS
                                    **:**::*:** : . .** :***:*