For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_2081 ()

annotation: POSSIBLE CONSERVED INTEGRAL MEMBRANE PROTEIN
coordinates: 4091315 - 4092235
length: 307

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2081-100% (307)POSSIBLE CONSERVED INTEGRAL MEMBRANE PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3836c-1e-12876.72% (305) phosphoribose diphosphate:decaprenyl-phosphate
M. gilvum PYR-GCKMflv_1162-1e-12170.72% (304) phosphoribose diphosphate:decaprenyl-phosphate
M. tuberculosis H37RvRv3806c-1e-12876.39% (305) phosphoribose diphosphate:decaprenyl-phosphate
M. leprae Br4923MLBr_00095-1e-12473.11% (305) phosphoribose diphosphate:decaprenyl-phosphate
M. abscessus ATCC 19977MAB_0173-1e-12874.84% (306) phosphoribose diphosphate:decaprenyl-phosphate
M. marinum MMMAR_5370-1e-12574.75% (305) transmembrane protein
M. avium 104MAV_0211-1e-12774.18% (306) phosphoribose diphosphate:decaprenyl-phosphate
M. smegmatis MC2 155MSMEG_6401-1e-13374.84% (314) phosphoribose diphosphate:decaprenyl-phosphate
M. ulcerans Agy99MUL_4990-1e-12574.75% (305) phosphoribose diphosphate:decaprenyl-phosphate
M. vanbaalenii PYR-1Mvan_5647-1e-12673.44% (305) phosphoribose diphosphate:decaprenyl-phosphate

CLUSTAL 2.0.9 multiple sequence alignment


Mb3836c|M.bovis_AF2122/97           -------MSEDVVTQPPANLVAGVVKAIRPRQWVKNVLVLAAPLAALG-G
Rv3806c|M.tuberculosis_H37Rv        -------MSEDVVTQPPANLVAGVVKAIRPRQWVKNVLVLAAPLAALG-G
MMAR_5370|M.marinum_M               -------MSEDVVTGPPTNLVAGVVKAMRPRQWVKNVLVLAAPLAAAG-R
MUL_4990|M.ulcerans_Agy99           -------MSEDVVTGPPTNLVAGVVKAMRPRQWVKNVLVLAAPLAAAG-R
MLBr_00095|M.leprae_Br4923          -------MSEDVMIGSSGNLVIGVVKAIRPRQWVKNVLVLAAPLAGLG-G
MAV_0211|M.avium_104                ----MTEETQEAVAGPPANVVSGVIKAIRPRQWVKNVLVLLAPVAALG-G
Mflv_1162|M.gilvum_PYR-GCK          MSTSEVARDANSTAGPPKNIVTGVIKAIRPRQWVKNLLVLAAPIAALG-G
Mvan_5647|M.vanbaalenii_PYR-1       MSTSEVQQDTGSTAGPPKNLASGIIKAIRPRQWVKNLLVLAAPIAALG-G
MSMEG_6401|M.smegmatis_MC2_155      MDATHMSEEAQPTAGPPKNLVSGLIKAVRPRQWIKNLLVLAAPLAAVG-S
TH_2081|M.thermoresistible__bu      -----MSEEAAPVAGPPKNLAAGIVKAVRPRQWVKNLLVFAAPLAALAGG
MAB_0173|M.abscessus_ATCC_1997      -----MSEEAAPTVGPPKNLVSGIVKAVRPRQWVKNILVFAAPLAALG-D
                                                   .. *:. *::**:*****:**:**: **:*. .  

Mb3836c|M.bovis_AF2122/97           GVRYDYVEVLSKVSMAFVVFSLAASAVYLVNDVRDVEADREHPTKRFRPI
Rv3806c|M.tuberculosis_H37Rv        GVRYDYVEVLSKVSMAFVVFSLAASAVYLVNDVRDVEADREHPTKRFRPI
MMAR_5370|M.marinum_M               GVRYGYAEVLFEVLVAFVVFSLAASAIYLINDVRDVEADREHPTKRFRPI
MUL_4990|M.ulcerans_Agy99           GVRYGYAEVLFEVLVAFVVFSLAASAIYLINDVRDVEADREHPTKRFRPI
MLBr_00095|M.leprae_Br4923          GMHYRYAELLTEVSLAFVVFSLAASSVYLINDVRDIEADQEHPTKRFRPI
MAV_0211|M.avium_104                PVQYDYTDVLGQVSVAFVVFSLAASSIYLVNDARDVEADREHPTKRFRPI
Mflv_1162|M.gilvum_PYR-GCK          DIRYDYDEMAINILIAFVAFSLAASCIYLVNDSRDVEADRQHPTKRFRPI
Mvan_5647|M.vanbaalenii_PYR-1       EVRYDYDEMAINILIAFVAFSLAASCIYLVNDSRDVEADRQHPTKRFRPI
MSMEG_6401|M.smegmatis_MC2_155      GIEYDYADVAAKVSVAFVVFCLAASSIYLINDARDVEADRAHPTKRFRPI
TH_2081|M.thermoresistible__bu      NMPDDHVGVLLRVGMAFVVFCLAASSVYLVNDARDVEADRQHPTKRFRPI
MAB_0173|M.abscessus_ATCC_1997      IPPHDYRTVFTKVAIAFVVFSMAASSIYLINDARDVEADRQHPTKRFRPI
                                         :  :  .: :***.*.:***.:**:** **:***: *********

Mb3836c|M.bovis_AF2122/97           AAGVVPEWLAYTVAVVLGVTSLAGAWMLTPNLALVMVVYLAMQLAYCFGL
Rv3806c|M.tuberculosis_H37Rv        AAGVVPEWLAYTVAVVLGVTSLAGAWMLTPNLALVMVVYLAMQLAYCFGL
MMAR_5370|M.marinum_M               AAGVVPEWLAYTLAVALGVTSLGLAWWLTPSLAVVMVVYLAMQLGYCFGL
MUL_4990|M.ulcerans_Agy99           AAGVVPEWLAYTLAVALGVTSLGLAWWLTPSLAVVMVVYLAMQLGYCFGL
MLBr_00095|M.leprae_Br4923          AAGVVTEWLAYTLAVVLGVASLVVAWLMTPNLALVMVIYIGMQLGYCFGL
MAV_0211|M.avium_104                AAGVVPEWLAYTLAVLLAAASLGIGWWLTPNLAAVMAVYIAIQLAYCFGL
Mflv_1162|M.gilvum_PYR-GCK          AAGVVPEWLAYTLAVVLGLAALGISLLASVNLTLVIGVYILMQLAYCFGL
Mvan_5647|M.vanbaalenii_PYR-1       AAGVVPEWLAYTLAVVLGVAALGISLLASPSLTVVIAVYIAMQLAYCFGL
MSMEG_6401|M.smegmatis_MC2_155      AAGVVPEWMAYSLAGLLAVASLVISWWLTANLAIVMAVYIAVQLAYCFGL
TH_2081|M.thermoresistible__bu      AAGVVSERLAYTLATVLGAGSLLLSWLVTPNLAVVMAIYIAVQLAYCFGL
MAB_0173|M.abscessus_ATCC_1997      AAGVLPVPAAYGLSVVLAAGSLAIASQVNANLVVVIAIYIAIQLGYCFGL
                                    ****:.   ** ::  *.  :*  .   . .*. *: :*: :**.*****

Mb3836c|M.bovis_AF2122/97           KHQAVVDICVVSSAYLIRAIAGGVATKIPLSKWFLLIMAFGSLFMVAGKR
Rv3806c|M.tuberculosis_H37Rv        KHQAVVEICVVSSAYLIRAIAGGVATKIPLSKWFLLIMAFGSLFMVAGKR
MMAR_5370|M.marinum_M               KHQAVIDICIVSSAYLIRAIAGGAATDIRLSQWFLLTAAFGSLFMVAGKR
MUL_4990|M.ulcerans_Agy99           KHQAVIDICIVSSAYLIRAIAGGAATDIRLSQWFLLTAAFGSLFMVAGKR
MLBr_00095|M.leprae_Br4923          KHQAVVDICIVSSAYLIRAIAGGVATNIPLSQWFLLTAAFGSLFMVAGKR
MAV_0211|M.avium_104                KHQAVMDICIVSSGFLLRAIAGGAATNIRLTQWFLLMMAFGSLFMAAGKR
Mflv_1162|M.gilvum_PYR-GCK          KHQAVLDICIVSSAYLIRAIAGGAAAGIPLSQWFLLVMTFGSLFMVAGKR
Mvan_5647|M.vanbaalenii_PYR-1       KHQAVLDICIVSSAYLIRAIAGGAAAGIPLSQWFLLVMTFGSLFMVAGKR
MSMEG_6401|M.smegmatis_MC2_155      KHQAVLDICIVSSGFLIRAIAGGVAADIPLSQWFLLVMAFGSLFMAAGKR
TH_2081|M.thermoresistible__bu      KHQAVLDICIVSSGFLIRAIAGGVAAGIWLSQWFLLVMAFGSLFMAAGKR
MAB_0173|M.abscessus_ATCC_1997      KHQPVIDICIVSSAYLIRAIAGGVAAGVYLSQWFLLIMAFGSLMMTAGKR
                                    ***.*::**:***.:*:******.*: : *::****  :****:*.****

Mb3836c|M.bovis_AF2122/97           YAELHLAERTGAAIRKSLESYTSTYLRFVWTLSATAVVLCYGLWAFERDG
Rv3806c|M.tuberculosis_H37Rv        YAELHLAERTGAAIRKSLESYTSTYLRFVWTLSATAVVLCYGLWAFERDG
MMAR_5370|M.marinum_M               YAELQLAERTGAAIRKSLESYTSTYLRFVWTLSATAVVVCYGLWAFERDN
MUL_4990|M.ulcerans_Agy99           YAELQLAERTGAAIRKSLESYTSTYLRFVWTLSATAVVVCYGLWAFERDN
MLBr_00095|M.leprae_Br4923          YAELQLTERTGAAIRKSLESYTSTYLRFVWTLSATAVVMCYGLWAFERDR
MAV_0211|M.avium_104                YAELQLAERTGAKIRKALESYTSTYLRFVWTLSATALVVCYGLWAFDREH
Mflv_1162|M.gilvum_PYR-GCK          YAELQLAERTGAKIRKSLESYTASYLRFVWTVAATSMVVCYSLWAFERDG
Mvan_5647|M.vanbaalenii_PYR-1       YAELQLAERTGAKIRKSLESYTASYLRFVWTVAATAMVVCYSLWAFERDG
MSMEG_6401|M.smegmatis_MC2_155      YAELQLAERTGAKIRKSLESYTSSYLRFVWTLSATAMVVCYGLWAFSRDR
TH_2081|M.thermoresistible__bu      YAELQLAERTGAKIRKSLENYTTTYLRFVWTMSATAVVLCYGLWAFEPDP
MAB_0173|M.abscessus_ATCC_1997      YAELQIVEKTGAKIRKSLEGYTASYLRFVWTLAATAVVVCYGLWAFERD-
                                    ****::.*:*** ***:**.**::*******::**::*:**.****. : 

Mb3836c|M.bovis_AF2122/97           Y---------SGSWFAVSMIPFTIAILRYAVDVDGGLAGEPEDIALRDRV
Rv3806c|M.tuberculosis_H37Rv        Y---------SGSWFAVSMIPFTIAILRYAVDVDGGLAGEPEDIALRDRV
MMAR_5370|M.marinum_M               Y---------SGSWFAASMVPFTIAILRYAVDVDGGLAGEPEEIALRDRV
MUL_4990|M.ulcerans_Agy99           Y---------SGSWFAASMVPFTIAILRYAVDVDGGLAGEPEEIALRDRV
MLBr_00095|M.leprae_Br4923          H---------SGSWFAVSMVPFTIAILRYAVDVDGGLAGEPEGIALRDRV
MAV_0211|M.avium_104                G---------EARWFVVSMVPFTIAILRYAVDVDGGLAGEPEDIVLRDRV
Mflv_1162|M.gilvum_PYR-GCK          A---------AASWYAVTIIPITIAILRYAVDVDGGLAGEPEEIALKDRV
Mvan_5647|M.vanbaalenii_PYR-1       A---------NASWYAVTIIPITIAILRYAVDVDGGLAGEPEEIALKDRV
MSMEG_6401|M.smegmatis_MC2_155      ANDLMTLDAQDASWYAVTMIPFTIAILRYAVDIDGGIAGEPEEIALKDRV
TH_2081|M.thermoresistible__bu      TR--------TSVWFVVSMIPFTIAILRYAVDVDSGMAGEPEEIALRDRV
MAB_0173|M.abscessus_ATCC_1997      HR--------AGSWFVASMIPFTIAVLRYAVDVDGGEAGEPEEIALGDRV
                                               . *:..:::*:***:******:*.* ***** *.* ***

Mb3836c|M.bovis_AF2122/97           LQLLALAWIATVGAAVAFG
Rv3806c|M.tuberculosis_H37Rv        LQLLALAWIATVGAAVAFG
MMAR_5370|M.marinum_M               LQLLALAWIGTVGAAVAFG
MUL_4990|M.ulcerans_Agy99           LQLLALAWIGTVGAAVAFG
MLBr_00095|M.leprae_Br4923          LQLLALTWAGTIGAAVVFG
MAV_0211|M.avium_104                FQLLALAWMVTVGAAVAFG
Mflv_1162|M.gilvum_PYR-GCK          LQLLLLTWVGTIGAAVFLG
Mvan_5647|M.vanbaalenii_PYR-1       LQLLLLAWIGTIGAAVFFG
MSMEG_6401|M.smegmatis_MC2_155      LQILFLAWIGTIGAAIYFS
TH_2081|M.thermoresistible__bu      LQLLAVAWIGTVGAAAFFS
MAB_0173|M.abscessus_ATCC_1997      LQFLFVAWIGSLGAAFYFS
                                    :*:* ::*  ::***  :.