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M. leprae Br4923 MLBr_00095 (-)

annotation: phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase
coordinates: 117897 - 118805
length: 302

MSEDVMIGSSGNLVIGVVKAIRPRQWVKNVLVLAAPLAGLGGGMHYRYAELLTEVSLAFVVFSLAASSVY
LINDVRDIEADQEHPTKRFRPIAAGVVTEWLAYTLAVVLGVASLVVAWLMTPNLALVMVIYIGMQLGYCF
GLKHQAVVDICIVSSAYLIRAIAGGVATNIPLSQWFLLTAAFGSLFMVAGKRYAELQLTERTGAAIRKSL
ESYTSTYLRFVWTLSATAVVMCYGLWAFERDRHSGSWFAVSMVPFTIAILRYAVDVDGGLAGEPEGIALR
DRVLQLLALTWAGTIGAAVVFG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_00095--100% (302)phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3836c-1e-14684.11% (302) phosphoribose diphosphate:decaprenyl-phosphate
M. gilvum PYR-GCKMflv_1162-1e-12573.90% (295) phosphoribose diphosphate:decaprenyl-phosphate
M. tuberculosis H37RvRv3806c-1e-14683.77% (302) phosphoribose diphosphate:decaprenyl-phosphate
M. abscessus ATCC 19977MAB_0173-1e-11868.65% (303) phosphoribose diphosphate:decaprenyl-phosphate
M. marinum MMMAR_5370-1e-14584.44% (302) transmembrane protein
M. avium 104MAV_0211-1e-13174.75% (301) phosphoribose diphosphate:decaprenyl-phosphate
M. smegmatis MC2 155MSMEG_6401-1e-12871.47% (312) phosphoribose diphosphate:decaprenyl-phosphate
M. thermoresistible (build 8)TH_2081-1e-12473.11% (305) POSSIBLE CONSERVED INTEGRAL MEMBRANE PROTEIN
M. ulcerans Agy99MUL_4990-1e-14584.44% (302) phosphoribose diphosphate:decaprenyl-phosphate
M. vanbaalenii PYR-1Mvan_5647-1e-12673.90% (295) phosphoribose diphosphate:decaprenyl-phosphate

CLUSTAL 2.0.9 multiple sequence alignment


Mb3836c|M.bovis_AF2122/97           -------MSEDVVTQPPANLVAGVVKAIRPRQWVKNVLVLAAPLAALG-G
Rv3806c|M.tuberculosis_H37Rv        -------MSEDVVTQPPANLVAGVVKAIRPRQWVKNVLVLAAPLAALG-G
MMAR_5370|M.marinum_M               -------MSEDVVTGPPTNLVAGVVKAMRPRQWVKNVLVLAAPLAAAG-R
MUL_4990|M.ulcerans_Agy99           -------MSEDVVTGPPTNLVAGVVKAMRPRQWVKNVLVLAAPLAAAG-R
MLBr_00095|M.leprae_Br4923          -------MSEDVMIGSSGNLVIGVVKAIRPRQWVKNVLVLAAPLAGLG-G
MAV_0211|M.avium_104                ----MTEETQEAVAGPPANVVSGVIKAIRPRQWVKNVLVLLAPVAALG-G
Mflv_1162|M.gilvum_PYR-GCK          MSTSEVARDANSTAGPPKNIVTGVIKAIRPRQWVKNLLVLAAPIAALG-G
Mvan_5647|M.vanbaalenii_PYR-1       MSTSEVQQDTGSTAGPPKNLASGIIKAIRPRQWVKNLLVLAAPIAALG-G
MSMEG_6401|M.smegmatis_MC2_155      MDATHMSEEAQPTAGPPKNLVSGLIKAVRPRQWIKNLLVLAAPLAAVG-S
MAB_0173|M.abscessus_ATCC_1997      -----MSEEAAPTVGPPKNLVSGIVKAVRPRQWVKNILVFAAPLAALG-D
TH_2081|M.thermoresistible__bu      -----MSEEAAPVAGPPKNLAAGIVKAVRPRQWVKNLLVFAAPLAALAGG
                                                   .. *:. *::**:*****:**:**: **:*. .  

Mb3836c|M.bovis_AF2122/97           GVRYDYVEVLSKVSMAFVVFSLAASAVYLVNDVRDVEADREHPTKRFRPI
Rv3806c|M.tuberculosis_H37Rv        GVRYDYVEVLSKVSMAFVVFSLAASAVYLVNDVRDVEADREHPTKRFRPI
MMAR_5370|M.marinum_M               GVRYGYAEVLFEVLVAFVVFSLAASAIYLINDVRDVEADREHPTKRFRPI
MUL_4990|M.ulcerans_Agy99           GVRYGYAEVLFEVLVAFVVFSLAASAIYLINDVRDVEADREHPTKRFRPI
MLBr_00095|M.leprae_Br4923          GMHYRYAELLTEVSLAFVVFSLAASSVYLINDVRDIEADQEHPTKRFRPI
MAV_0211|M.avium_104                PVQYDYTDVLGQVSVAFVVFSLAASSIYLVNDARDVEADREHPTKRFRPI
Mflv_1162|M.gilvum_PYR-GCK          DIRYDYDEMAINILIAFVAFSLAASCIYLVNDSRDVEADRQHPTKRFRPI
Mvan_5647|M.vanbaalenii_PYR-1       EVRYDYDEMAINILIAFVAFSLAASCIYLVNDSRDVEADRQHPTKRFRPI
MSMEG_6401|M.smegmatis_MC2_155      GIEYDYADVAAKVSVAFVVFCLAASSIYLINDARDVEADRAHPTKRFRPI
MAB_0173|M.abscessus_ATCC_1997      IPPHDYRTVFTKVAIAFVVFSMAASSIYLINDARDVEADRQHPTKRFRPI
TH_2081|M.thermoresistible__bu      NMPDDHVGVLLRVGMAFVVFCLAASSVYLVNDARDVEADRQHPTKRFRPI
                                         :  :  .: :***.*.:***.:**:** **:***: *********

Mb3836c|M.bovis_AF2122/97           AAGVVPEWLAYTVAVVLGVTSLAGAWMLTPNLALVMVVYLAMQLAYCFGL
Rv3806c|M.tuberculosis_H37Rv        AAGVVPEWLAYTVAVVLGVTSLAGAWMLTPNLALVMVVYLAMQLAYCFGL
MMAR_5370|M.marinum_M               AAGVVPEWLAYTLAVALGVTSLGLAWWLTPSLAVVMVVYLAMQLGYCFGL
MUL_4990|M.ulcerans_Agy99           AAGVVPEWLAYTLAVALGVTSLGLAWWLTPSLAVVMVVYLAMQLGYCFGL
MLBr_00095|M.leprae_Br4923          AAGVVTEWLAYTLAVVLGVASLVVAWLMTPNLALVMVIYIGMQLGYCFGL
MAV_0211|M.avium_104                AAGVVPEWLAYTLAVLLAAASLGIGWWLTPNLAAVMAVYIAIQLAYCFGL
Mflv_1162|M.gilvum_PYR-GCK          AAGVVPEWLAYTLAVVLGLAALGISLLASVNLTLVIGVYILMQLAYCFGL
Mvan_5647|M.vanbaalenii_PYR-1       AAGVVPEWLAYTLAVVLGVAALGISLLASPSLTVVIAVYIAMQLAYCFGL
MSMEG_6401|M.smegmatis_MC2_155      AAGVVPEWMAYSLAGLLAVASLVISWWLTANLAIVMAVYIAVQLAYCFGL
MAB_0173|M.abscessus_ATCC_1997      AAGVLPVPAAYGLSVVLAAGSLAIASQVNANLVVVIAIYIAIQLGYCFGL
TH_2081|M.thermoresistible__bu      AAGVVSERLAYTLATVLGAGSLLLSWLVTPNLAVVMAIYIAVQLAYCFGL
                                    ****:.   ** ::  *.  :*  .   . .*. *: :*: :**.*****

Mb3836c|M.bovis_AF2122/97           KHQAVVDICVVSSAYLIRAIAGGVATKIPLSKWFLLIMAFGSLFMVAGKR
Rv3806c|M.tuberculosis_H37Rv        KHQAVVEICVVSSAYLIRAIAGGVATKIPLSKWFLLIMAFGSLFMVAGKR
MMAR_5370|M.marinum_M               KHQAVIDICIVSSAYLIRAIAGGAATDIRLSQWFLLTAAFGSLFMVAGKR
MUL_4990|M.ulcerans_Agy99           KHQAVIDICIVSSAYLIRAIAGGAATDIRLSQWFLLTAAFGSLFMVAGKR
MLBr_00095|M.leprae_Br4923          KHQAVVDICIVSSAYLIRAIAGGVATNIPLSQWFLLTAAFGSLFMVAGKR
MAV_0211|M.avium_104                KHQAVMDICIVSSGFLLRAIAGGAATNIRLTQWFLLMMAFGSLFMAAGKR
Mflv_1162|M.gilvum_PYR-GCK          KHQAVLDICIVSSAYLIRAIAGGAAAGIPLSQWFLLVMTFGSLFMVAGKR
Mvan_5647|M.vanbaalenii_PYR-1       KHQAVLDICIVSSAYLIRAIAGGAAAGIPLSQWFLLVMTFGSLFMVAGKR
MSMEG_6401|M.smegmatis_MC2_155      KHQAVLDICIVSSGFLIRAIAGGVAADIPLSQWFLLVMAFGSLFMAAGKR
MAB_0173|M.abscessus_ATCC_1997      KHQPVIDICIVSSAYLIRAIAGGVAAGVYLSQWFLLIMAFGSLMMTAGKR
TH_2081|M.thermoresistible__bu      KHQAVLDICIVSSGFLIRAIAGGVAAGIWLSQWFLLVMAFGSLFMAAGKR
                                    ***.*::**:***.:*:******.*: : *::****  :****:*.****

Mb3836c|M.bovis_AF2122/97           YAELHLAERTGAAIRKSLESYTSTYLRFVWTLSATAVVLCYGLWAFERDG
Rv3806c|M.tuberculosis_H37Rv        YAELHLAERTGAAIRKSLESYTSTYLRFVWTLSATAVVLCYGLWAFERDG
MMAR_5370|M.marinum_M               YAELQLAERTGAAIRKSLESYTSTYLRFVWTLSATAVVVCYGLWAFERDN
MUL_4990|M.ulcerans_Agy99           YAELQLAERTGAAIRKSLESYTSTYLRFVWTLSATAVVVCYGLWAFERDN
MLBr_00095|M.leprae_Br4923          YAELQLTERTGAAIRKSLESYTSTYLRFVWTLSATAVVMCYGLWAFERDR
MAV_0211|M.avium_104                YAELQLAERTGAKIRKALESYTSTYLRFVWTLSATALVVCYGLWAFDREH
Mflv_1162|M.gilvum_PYR-GCK          YAELQLAERTGAKIRKSLESYTASYLRFVWTVAATSMVVCYSLWAFERDG
Mvan_5647|M.vanbaalenii_PYR-1       YAELQLAERTGAKIRKSLESYTASYLRFVWTVAATAMVVCYSLWAFERDG
MSMEG_6401|M.smegmatis_MC2_155      YAELQLAERTGAKIRKSLESYTSSYLRFVWTLSATAMVVCYGLWAFSRDR
MAB_0173|M.abscessus_ATCC_1997      YAELQIVEKTGAKIRKSLEGYTASYLRFVWTLAATAVVVCYGLWAFERD-
TH_2081|M.thermoresistible__bu      YAELQLAERTGAKIRKSLENYTTTYLRFVWTMSATAVVLCYGLWAFEPDP
                                    ****::.*:*** ***:**.**::*******::**::*:**.****. : 

Mb3836c|M.bovis_AF2122/97           Y---------SGSWFAVSMIPFTIAILRYAVDVDGGLAGEPEDIALRDRV
Rv3806c|M.tuberculosis_H37Rv        Y---------SGSWFAVSMIPFTIAILRYAVDVDGGLAGEPEDIALRDRV
MMAR_5370|M.marinum_M               Y---------SGSWFAASMVPFTIAILRYAVDVDGGLAGEPEEIALRDRV
MUL_4990|M.ulcerans_Agy99           Y---------SGSWFAASMVPFTIAILRYAVDVDGGLAGEPEEIALRDRV
MLBr_00095|M.leprae_Br4923          H---------SGSWFAVSMVPFTIAILRYAVDVDGGLAGEPEGIALRDRV
MAV_0211|M.avium_104                G---------EARWFVVSMVPFTIAILRYAVDVDGGLAGEPEDIVLRDRV
Mflv_1162|M.gilvum_PYR-GCK          A---------AASWYAVTIIPITIAILRYAVDVDGGLAGEPEEIALKDRV
Mvan_5647|M.vanbaalenii_PYR-1       A---------NASWYAVTIIPITIAILRYAVDVDGGLAGEPEEIALKDRV
MSMEG_6401|M.smegmatis_MC2_155      ANDLMTLDAQDASWYAVTMIPFTIAILRYAVDIDGGIAGEPEEIALKDRV
MAB_0173|M.abscessus_ATCC_1997      HR--------AGSWFVASMIPFTIAVLRYAVDVDGGEAGEPEEIALGDRV
TH_2081|M.thermoresistible__bu      TR--------TSVWFVVSMIPFTIAILRYAVDVDSGMAGEPEEIALRDRV
                                               . *:..:::*:***:******:*.* ***** *.* ***

Mb3836c|M.bovis_AF2122/97           LQLLALAWIATVGAAVAFG
Rv3806c|M.tuberculosis_H37Rv        LQLLALAWIATVGAAVAFG
MMAR_5370|M.marinum_M               LQLLALAWIGTVGAAVAFG
MUL_4990|M.ulcerans_Agy99           LQLLALAWIGTVGAAVAFG
MLBr_00095|M.leprae_Br4923          LQLLALTWAGTIGAAVVFG
MAV_0211|M.avium_104                FQLLALAWMVTVGAAVAFG
Mflv_1162|M.gilvum_PYR-GCK          LQLLLLTWVGTIGAAVFLG
Mvan_5647|M.vanbaalenii_PYR-1       LQLLLLAWIGTIGAAVFFG
MSMEG_6401|M.smegmatis_MC2_155      LQILFLAWIGTIGAAIYFS
MAB_0173|M.abscessus_ATCC_1997      LQFLFVAWIGSLGAAFYFS
TH_2081|M.thermoresistible__bu      LQLLAVAWIGTVGAAAFFS
                                    :*:* ::*  ::***  :.