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MSTSEVARDANSTAGPPKNIVTGVIKAIRPRQWVKNLLVLAAPIAALGGDIRYDYDEMAINILIAFVAFS LAASCIYLVNDSRDVEADRQHPTKRFRPIAAGVVPEWLAYTLAVVLGLAALGISLLASVNLTLVIGVYIL MQLAYCFGLKHQAVLDICIVSSAYLIRAIAGGAAAGIPLSQWFLLVMTFGSLFMVAGKRYAELQLAERTG AKIRKSLESYTASYLRFVWTVAATSMVVCYSLWAFERDGAAASWYAVTIIPITIAILRYAVDVDGGLAGE PEEIALKDRVLQLLLLTWVGTIGAAVFLG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1162 | - | - | 100% (309) | phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3836c | - | 1e-130 | 75.51% (294) | phosphoribose diphosphate:decaprenyl-phosphate |
| M. tuberculosis H37Rv | Rv3806c | - | 1e-130 | 75.17% (294) | phosphoribose diphosphate:decaprenyl-phosphate |
| M. leprae Br4923 | MLBr_00095 | - | 1e-126 | 73.90% (295) | phosphoribose diphosphate:decaprenyl-phosphate |
| M. abscessus ATCC 19977 | MAB_0173 | - | 1e-121 | 68.54% (302) | phosphoribose diphosphate:decaprenyl-phosphate |
| M. marinum M | MMAR_5370 | - | 1e-129 | 74.58% (295) | transmembrane protein |
| M. avium 104 | MAV_0211 | - | 1e-127 | 72.48% (298) | phosphoribose diphosphate:decaprenyl-phosphate |
| M. smegmatis MC2 155 | MSMEG_6401 | - | 1e-133 | 72.78% (316) | phosphoribose diphosphate:decaprenyl-phosphate |
| M. thermoresistible (build 8) | TH_2081 | - | 1e-121 | 70.72% (304) | POSSIBLE CONSERVED INTEGRAL MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_4990 | - | 1e-129 | 74.58% (295) | phosphoribose diphosphate:decaprenyl-phosphate |
| M. vanbaalenii PYR-1 | Mvan_5647 | - | 1e-163 | 93.20% (309) | phosphoribose diphosphate:decaprenyl-phosphate |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1162|M.gilvum_PYR-GCK MSTSEVARDANSTAGPPKNIVTGVIKAIRPRQWVKNLLVLAAPIAALG-G
Mvan_5647|M.vanbaalenii_PYR-1 MSTSEVQQDTGSTAGPPKNLASGIIKAIRPRQWVKNLLVLAAPIAALG-G
Mb3836c|M.bovis_AF2122/97 -------MSEDVVTQPPANLVAGVVKAIRPRQWVKNVLVLAAPLAALG-G
Rv3806c|M.tuberculosis_H37Rv -------MSEDVVTQPPANLVAGVVKAIRPRQWVKNVLVLAAPLAALG-G
MMAR_5370|M.marinum_M -------MSEDVVTGPPTNLVAGVVKAMRPRQWVKNVLVLAAPLAAAG-R
MUL_4990|M.ulcerans_Agy99 -------MSEDVVTGPPTNLVAGVVKAMRPRQWVKNVLVLAAPLAAAG-R
MLBr_00095|M.leprae_Br4923 -------MSEDVMIGSSGNLVIGVVKAIRPRQWVKNVLVLAAPLAGLG-G
MAV_0211|M.avium_104 ----MTEETQEAVAGPPANVVSGVIKAIRPRQWVKNVLVLLAPVAALG-G
MSMEG_6401|M.smegmatis_MC2_155 MDATHMSEEAQPTAGPPKNLVSGLIKAVRPRQWIKNLLVLAAPLAAVG-S
MAB_0173|M.abscessus_ATCC_1997 -----MSEEAAPTVGPPKNLVSGIVKAVRPRQWVKNILVFAAPLAALG-D
TH_2081|M.thermoresistible__bu -----MSEEAAPVAGPPKNLAAGIVKAVRPRQWVKNLLVFAAPLAALAGG
.. *:. *::**:*****:**:**: **:*. .
Mflv_1162|M.gilvum_PYR-GCK DIRYDYDEMAINILIAFVAFSLAASCIYLVNDSRDVEADRQHPTKRFRPI
Mvan_5647|M.vanbaalenii_PYR-1 EVRYDYDEMAINILIAFVAFSLAASCIYLVNDSRDVEADRQHPTKRFRPI
Mb3836c|M.bovis_AF2122/97 GVRYDYVEVLSKVSMAFVVFSLAASAVYLVNDVRDVEADREHPTKRFRPI
Rv3806c|M.tuberculosis_H37Rv GVRYDYVEVLSKVSMAFVVFSLAASAVYLVNDVRDVEADREHPTKRFRPI
MMAR_5370|M.marinum_M GVRYGYAEVLFEVLVAFVVFSLAASAIYLINDVRDVEADREHPTKRFRPI
MUL_4990|M.ulcerans_Agy99 GVRYGYAEVLFEVLVAFVVFSLAASAIYLINDVRDVEADREHPTKRFRPI
MLBr_00095|M.leprae_Br4923 GMHYRYAELLTEVSLAFVVFSLAASSVYLINDVRDIEADQEHPTKRFRPI
MAV_0211|M.avium_104 PVQYDYTDVLGQVSVAFVVFSLAASSIYLVNDARDVEADREHPTKRFRPI
MSMEG_6401|M.smegmatis_MC2_155 GIEYDYADVAAKVSVAFVVFCLAASSIYLINDARDVEADRAHPTKRFRPI
MAB_0173|M.abscessus_ATCC_1997 IPPHDYRTVFTKVAIAFVVFSMAASSIYLINDARDVEADRQHPTKRFRPI
TH_2081|M.thermoresistible__bu NMPDDHVGVLLRVGMAFVVFCLAASSVYLVNDARDVEADRQHPTKRFRPI
: : .: :***.*.:***.:**:** **:***: *********
Mflv_1162|M.gilvum_PYR-GCK AAGVVPEWLAYTLAVVLGLAALGISLLASVNLTLVIGVYILMQLAYCFGL
Mvan_5647|M.vanbaalenii_PYR-1 AAGVVPEWLAYTLAVVLGVAALGISLLASPSLTVVIAVYIAMQLAYCFGL
Mb3836c|M.bovis_AF2122/97 AAGVVPEWLAYTVAVVLGVTSLAGAWMLTPNLALVMVVYLAMQLAYCFGL
Rv3806c|M.tuberculosis_H37Rv AAGVVPEWLAYTVAVVLGVTSLAGAWMLTPNLALVMVVYLAMQLAYCFGL
MMAR_5370|M.marinum_M AAGVVPEWLAYTLAVALGVTSLGLAWWLTPSLAVVMVVYLAMQLGYCFGL
MUL_4990|M.ulcerans_Agy99 AAGVVPEWLAYTLAVALGVTSLGLAWWLTPSLAVVMVVYLAMQLGYCFGL
MLBr_00095|M.leprae_Br4923 AAGVVTEWLAYTLAVVLGVASLVVAWLMTPNLALVMVIYIGMQLGYCFGL
MAV_0211|M.avium_104 AAGVVPEWLAYTLAVLLAAASLGIGWWLTPNLAAVMAVYIAIQLAYCFGL
MSMEG_6401|M.smegmatis_MC2_155 AAGVVPEWMAYSLAGLLAVASLVISWWLTANLAIVMAVYIAVQLAYCFGL
MAB_0173|M.abscessus_ATCC_1997 AAGVLPVPAAYGLSVVLAAGSLAIASQVNANLVVVIAIYIAIQLGYCFGL
TH_2081|M.thermoresistible__bu AAGVVSERLAYTLATVLGAGSLLLSWLVTPNLAVVMAIYIAVQLAYCFGL
****:. ** :: *. :* . . .*. *: :*: :**.*****
Mflv_1162|M.gilvum_PYR-GCK KHQAVLDICIVSSAYLIRAIAGGAAAGIPLSQWFLLVMTFGSLFMVAGKR
Mvan_5647|M.vanbaalenii_PYR-1 KHQAVLDICIVSSAYLIRAIAGGAAAGIPLSQWFLLVMTFGSLFMVAGKR
Mb3836c|M.bovis_AF2122/97 KHQAVVDICVVSSAYLIRAIAGGVATKIPLSKWFLLIMAFGSLFMVAGKR
Rv3806c|M.tuberculosis_H37Rv KHQAVVEICVVSSAYLIRAIAGGVATKIPLSKWFLLIMAFGSLFMVAGKR
MMAR_5370|M.marinum_M KHQAVIDICIVSSAYLIRAIAGGAATDIRLSQWFLLTAAFGSLFMVAGKR
MUL_4990|M.ulcerans_Agy99 KHQAVIDICIVSSAYLIRAIAGGAATDIRLSQWFLLTAAFGSLFMVAGKR
MLBr_00095|M.leprae_Br4923 KHQAVVDICIVSSAYLIRAIAGGVATNIPLSQWFLLTAAFGSLFMVAGKR
MAV_0211|M.avium_104 KHQAVMDICIVSSGFLLRAIAGGAATNIRLTQWFLLMMAFGSLFMAAGKR
MSMEG_6401|M.smegmatis_MC2_155 KHQAVLDICIVSSGFLIRAIAGGVAADIPLSQWFLLVMAFGSLFMAAGKR
MAB_0173|M.abscessus_ATCC_1997 KHQPVIDICIVSSAYLIRAIAGGVAAGVYLSQWFLLIMAFGSLMMTAGKR
TH_2081|M.thermoresistible__bu KHQAVLDICIVSSGFLIRAIAGGVAAGIWLSQWFLLVMAFGSLFMAAGKR
***.*::**:***.:*:******.*: : *::**** :****:*.****
Mflv_1162|M.gilvum_PYR-GCK YAELQLAERTGAKIRKSLESYTASYLRFVWTVAATSMVVCYSLWAFERDG
Mvan_5647|M.vanbaalenii_PYR-1 YAELQLAERTGAKIRKSLESYTASYLRFVWTVAATAMVVCYSLWAFERDG
Mb3836c|M.bovis_AF2122/97 YAELHLAERTGAAIRKSLESYTSTYLRFVWTLSATAVVLCYGLWAFERDG
Rv3806c|M.tuberculosis_H37Rv YAELHLAERTGAAIRKSLESYTSTYLRFVWTLSATAVVLCYGLWAFERDG
MMAR_5370|M.marinum_M YAELQLAERTGAAIRKSLESYTSTYLRFVWTLSATAVVVCYGLWAFERDN
MUL_4990|M.ulcerans_Agy99 YAELQLAERTGAAIRKSLESYTSTYLRFVWTLSATAVVVCYGLWAFERDN
MLBr_00095|M.leprae_Br4923 YAELQLTERTGAAIRKSLESYTSTYLRFVWTLSATAVVMCYGLWAFERDR
MAV_0211|M.avium_104 YAELQLAERTGAKIRKALESYTSTYLRFVWTLSATALVVCYGLWAFDREH
MSMEG_6401|M.smegmatis_MC2_155 YAELQLAERTGAKIRKSLESYTSSYLRFVWTLSATAMVVCYGLWAFSRDR
MAB_0173|M.abscessus_ATCC_1997 YAELQIVEKTGAKIRKSLEGYTASYLRFVWTLAATAVVVCYGLWAFERD-
TH_2081|M.thermoresistible__bu YAELQLAERTGAKIRKSLENYTTTYLRFVWTMSATAVVLCYGLWAFEPDP
****::.*:*** ***:**.**::*******::**::*:**.****. :
Mflv_1162|M.gilvum_PYR-GCK A---------AASWYAVTIIPITIAILRYAVDVDGGLAGEPEEIALKDRV
Mvan_5647|M.vanbaalenii_PYR-1 A---------NASWYAVTIIPITIAILRYAVDVDGGLAGEPEEIALKDRV
Mb3836c|M.bovis_AF2122/97 Y---------SGSWFAVSMIPFTIAILRYAVDVDGGLAGEPEDIALRDRV
Rv3806c|M.tuberculosis_H37Rv Y---------SGSWFAVSMIPFTIAILRYAVDVDGGLAGEPEDIALRDRV
MMAR_5370|M.marinum_M Y---------SGSWFAASMVPFTIAILRYAVDVDGGLAGEPEEIALRDRV
MUL_4990|M.ulcerans_Agy99 Y---------SGSWFAASMVPFTIAILRYAVDVDGGLAGEPEEIALRDRV
MLBr_00095|M.leprae_Br4923 H---------SGSWFAVSMVPFTIAILRYAVDVDGGLAGEPEGIALRDRV
MAV_0211|M.avium_104 G---------EARWFVVSMVPFTIAILRYAVDVDGGLAGEPEDIVLRDRV
MSMEG_6401|M.smegmatis_MC2_155 ANDLMTLDAQDASWYAVTMIPFTIAILRYAVDIDGGIAGEPEEIALKDRV
MAB_0173|M.abscessus_ATCC_1997 HR--------AGSWFVASMIPFTIAVLRYAVDVDGGEAGEPEEIALGDRV
TH_2081|M.thermoresistible__bu TR--------TSVWFVVSMIPFTIAILRYAVDVDSGMAGEPEEIALRDRV
. *:..:::*:***:******:*.* ***** *.* ***
Mflv_1162|M.gilvum_PYR-GCK LQLLLLTWVGTIGAAVFLG
Mvan_5647|M.vanbaalenii_PYR-1 LQLLLLAWIGTIGAAVFFG
Mb3836c|M.bovis_AF2122/97 LQLLALAWIATVGAAVAFG
Rv3806c|M.tuberculosis_H37Rv LQLLALAWIATVGAAVAFG
MMAR_5370|M.marinum_M LQLLALAWIGTVGAAVAFG
MUL_4990|M.ulcerans_Agy99 LQLLALAWIGTVGAAVAFG
MLBr_00095|M.leprae_Br4923 LQLLALTWAGTIGAAVVFG
MAV_0211|M.avium_104 FQLLALAWMVTVGAAVAFG
MSMEG_6401|M.smegmatis_MC2_155 LQILFLAWIGTIGAAIYFS
MAB_0173|M.abscessus_ATCC_1997 LQFLFVAWIGSLGAAFYFS
TH_2081|M.thermoresistible__bu LQLLAVAWIGTVGAAAFFS
:*:* ::* ::*** :.