For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_2003 (thrC)

annotation: PROBABLE THREONINE SYNTHASE THRC
coordinates: 3900083 - 3901165
length: 361

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_2003 thrC - 100% (361) PROBABLE THREONINE SYNTHASE THRC
M. thermoresistible (build 8) TH_1800 ilvA 1e-17 28.66% (307) Probable threonine dehydratase ilvA
M. thermoresistible (build 8) TH_1075 trpB 1e-09 22.54% (346) Probable tryptophan synthase, beta subunit trpB

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1327 thrC 1e-175 83.84% (359) threonine synthase
M. gilvum PYR-GCK Mflv_2299 - 1e-180 87.39% (357) threonine synthase
M. tuberculosis H37Rv Rv1295 thrC 1e-175 83.84% (359) threonine synthase
M. leprae Br4923 MLBr_01130 thrC 1e-176 84.68% (359) threonine synthase
M. abscessus ATCC 19977 MAB_1436 - 1e-169 81.82% (352) threonine synthase
M. marinum M MMAR_4102 thrC 1e-178 85.24% (359) threonine synthase ThrC
M. avium 104 MAV_1510 thrC 0.0 86.35% (359) threonine synthase
M. smegmatis MC2 155 MSMEG_4956 thrC 1e-180 86.63% (359) threonine synthase
M. ulcerans Agy99 MUL_3969 thrC 1e-177 84.68% (359) threonine synthase
M. vanbaalenii PYR-1 Mvan_4347 - 1e-179 87.78% (352) threonine synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2299|M.gilvum_PYR-GCK          -MSATRAVHQPWPGLIEAYRDRLPIEDSWTPITLREGGTPLLPAPRLSEY
Mvan_4347|M.vanbaalenii_PYR-1       -MSTARAVHQPWPGLIEAYRDRLPIEDSWTTITLREGGTPLLPAPRLSEY
TH_2003|M.thermoresistible__bu      LSAADTPVHRAWPGLIEAYRSRLPVGPGWTPITLHEGGTPLVPAPRLSEL
Mb1327|M.bovis_AF2122/97            MTVPPTATHQPWPGVIAAYRDRLPVGDDWTPVTLLEGGTPLIAATNLSKQ
Rv1295|M.tuberculosis_H37Rv         MTVPPTATHQPWPGVIAAYRDRLPVGDDWTPVTLLEGGTPLIAATNLSKQ
MLBr_01130|M.leprae_Br4923          MSGQQTTTHQPWPGVIAAYRDRLPVGDDWTPVTLLEGGTPLIAAPRLSEQ
MMAR_4102|M.marinum_M               MSASPTAVHKPWPGLIAAYRDRLPVADDWAPVTLLEGGTPLIAAPRLSKQ
MUL_3969|M.ulcerans_Agy99           MSASPTAVHKPWPGLIAAYRDRLPVADDWAPVTLLEGGTPLIAAPRLSKQ
MAV_1510|M.avium_104                MSAQRTAVHQPWPGLIEAYRDRLPVGDDWTPVTLLEGGTPLIPARRLSEK
MSMEG_4956|M.smegmatis_MC2_155      MSAAKAAVHQPWPGLIEAYRDRLPIGDDWTTVTLLEGGTPLIHAKRISEL
MAB_1436|M.abscessus_ATCC_1997      -----MTVHTPWPGLIAAYRDRLPIGENWQPVTLREGGTPLLPAARLSEL
                                          ..* .***:* ***.***:  .* .:** ******: * .:*: 

Mflv_2299|M.gilvum_PYR-GCK          TGCTVHLKVEGLNPTGSFKDRGMTMAVTEAVSRGQQAVLCASTGNTSASA
Mvan_4347|M.vanbaalenii_PYR-1       TGCTVHLKVEGLNPTGSFKDRGMTMAVTEAVSRGQQAVLCASTGNTSASA
TH_2003|M.thermoresistible__bu      LGCTVYLKVEGLNPTGSFKDRGMTVAVTEAVARGQKAVLCASTGNTSASA
Mb1327|M.bovis_AF2122/97            TGCTIHLKVEGLNPTGSFKDRGMTMAVTDALAHGQRAVLCASTGNTSASA
Rv1295|M.tuberculosis_H37Rv         TGCTIHLKVEGLNPTGSFKDRGMTMAVTDALAHGQRAVLCASTGNTSASA
MLBr_01130|M.leprae_Br4923          TGCTIHLKVEGLNPTGSFKDRGMTMAVTDALARGQRAVLCASTGNTSASA
MMAR_4102|M.marinum_M               TGCTIHLKVEGLNPTGSFKDRGMTMAVTDALARGQQAVLCASTGNTSASA
MUL_3969|M.ulcerans_Agy99           TGCTIHLKVEGLNPTGSFKDRGMTMAVTDALARGQQAVLCASTGNTSASA
MAV_1510|M.avium_104                TGCTVHLKVEGLNPTGSFKDRGMTMAVTDALARGQQAVLCASTGNTSASA
MSMEG_4956|M.smegmatis_MC2_155      TGCTVHLKVEGLNPTGSFKDRGMTVAVTESLARGQQAVLCASTGNTSASA
MAB_1436|M.abscessus_ATCC_1997      TGCTVHLKVEGLNPTGSFKDRGMTMAVTDALARGQRAVLCASTGNTSASA
                                     ***::******************:***:::::**:**************

Mflv_2299|M.gilvum_PYR-GCK          AAYAARAGITCAVLVPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELAR
Mvan_4347|M.vanbaalenii_PYR-1       AAYAARAGITCAVLVPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELAR
TH_2003|M.thermoresistible__bu      AAYAARAGITCAVLVPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELAR
Mb1327|M.bovis_AF2122/97            AAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELAR
Rv1295|M.tuberculosis_H37Rv         AAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELAR
MLBr_01130|M.leprae_Br4923          AAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELAR
MMAR_4102|M.marinum_M               AAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELAR
MUL_3969|M.ulcerans_Agy99           AAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELAR
MAV_1510|M.avium_104                AAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELAR
MSMEG_4956|M.smegmatis_MC2_155      AAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQVDGNFDDCLELAR
MAB_1436|M.abscessus_ATCC_1997      AAYAAKAGITCAVLIPQGKIAMGKLAQAVIHGARIIQVDGNFDDCLELAR
                                    *****:********:**************:***:***:************

Mflv_2299|M.gilvum_PYR-GCK          KLTADFPTVSLVNSVNPFRIEGQKTAAFEIVDALGDAPDIHALPVGNAGN
Mvan_4347|M.vanbaalenii_PYR-1       KLTSDFPTVSLVNSVNPFRIEGQKTAAFEIVDALGDAPDVHSLPVGNAGN
TH_2003|M.thermoresistible__bu      KLTADFPTISLVNSVNKYRIEGQKTAAFEIVDVLGTAPDVHALPVGNAGN
Mb1327|M.bovis_AF2122/97            KMAADFPTISLVNSVNPVRIEGQKTAAFEIVDVLGTAPDVHALPVGNAGN
Rv1295|M.tuberculosis_H37Rv         KMAADFPTISLVNSVNPVRIEGQKTAAFEIVDVLGTAPDVHALPVGNAGN
MLBr_01130|M.leprae_Br4923          KMAADFPMISLVNSVNPVRIEGQKTAVFEIVDALGTAPHVHALPVGNAGN
MMAR_4102|M.marinum_M               KMAADFPTISLVNSVNPVRIEGQKTAAFEIVDALGVAPDVHALPVGNAGN
MUL_3969|M.ulcerans_Agy99           KMAADFPTISLVNSVNPVRIEGQKTAAFEIVDALGVAPDVHALPVGNAGN
MAV_1510|M.avium_104                KMAADFPTISLVNSVNPVRIEGQKTAAFEIVDVLGAAPDVHALPVGNAGN
MSMEG_4956|M.smegmatis_MC2_155      KLTADFPTIALVNSVNPYRIEGQKTAAFEIVDALGTAPDVHALPVGNAGN
MAB_1436|M.abscessus_ATCC_1997      KTTADYPTIALVNSVNPVRIEGQKTAAFEIVDALGTAPDIHALPVGNAGN
                                    * ::*:* ::******  ********.*****.** **.:*:********

Mflv_2299|M.gilvum_PYR-GCK          ITAYWKGYTEYHRDGLASRLPRMLGTQAAGAAPLVLGEPVSDPETIATAI
Mvan_4347|M.vanbaalenii_PYR-1       ITAYWKGYTEYHRDGLAARLPRMLGTQAAGAAPLVLGEPVSDPETIATAI
TH_2003|M.thermoresistible__bu      ITAYWKGYTEYHRDGLTDRLPRMLGTQAAGAAPLVHGAPVRDPETIATAI
Mb1327|M.bovis_AF2122/97            ITAYWKGYTEYHQLGLIDKLPRMLGTQAAGAAPLVLGEPVSHPETIATAI
Rv1295|M.tuberculosis_H37Rv         ITAYWKGYTEYHQLGLIDKLPRMLGTQAAGAAPLVLGEPVSHPETIATAI
MLBr_01130|M.leprae_Br4923          ITAYWKGYTEYHADGLIDRLPRMLGTQAAGAAPLVLGEPVSHPETIATAI
MMAR_4102|M.marinum_M               ITAYWKGYTEYHRDGIIEKLPRMLGTQAAGAAPLVLGEPVNHPETIATAI
MUL_3969|M.ulcerans_Agy99           ITAYWKGYTEYHRDGIIEKLPRMLGTQAAGAAPLVLGEPVNHPETIATAI
MAV_1510|M.avium_104                ITAYWKGYTEYHHEGLIEKLPRMLGTQAAGAAPLVHGEPVKNPETIATAI
MSMEG_4956|M.smegmatis_MC2_155      ITAYWKGYSEYHRDGVSDRLPRMLGTQAAGAAPLVTGAPVKDPETIATAI
MAB_1436|M.abscessus_ATCC_1997      ITAYWRGYNEYHRDGLSDRLPKMLGAQAAGAAPLVNGAPVANPETIATAI
                                    *****:**.***  *:  :**:***:********* * ** .********

Mflv_2299|M.gilvum_PYR-GCK          RIGSPASWSSAVEAQQQSDGRFLAATDEEILAAYHLVARAEGVFVEPASA
Mvan_4347|M.vanbaalenii_PYR-1       RIGSPASWSSAVEAQQQSGGRFVAATDEEILAAYHLVARAEGVFVEPASA
TH_2003|M.thermoresistible__bu      RIGSPASWSSAVEARDQSGGRFLAATDEEILAAYHQVASAEGVFVEPASA
Mb1327|M.bovis_AF2122/97            RIGSPASWTSAVEAQQQSKGRFLAASDEEILAAYHLVARVEGVFVEPASA
Rv1295|M.tuberculosis_H37Rv         RIGSPASWTSAVEAQQQSKGRFLAASDEEILAAYHLVARVEGVFVEPASA
MLBr_01130|M.leprae_Br4923          RIGSPASWTSAVEAQQQSKGRFLAATDEEILAAYHLVARAEGVFVEPASA
MMAR_4102|M.marinum_M               RIGSPASWTSAVEAQQQSKGRFLAATDEEILAAYHLVARAEGVFVEPASA
MUL_3969|M.ulcerans_Agy99           RIGSPASWTSAVEAQQQSKGRFLAATDGEILAAYHLVARAEGVFVEPASA
MAV_1510|M.avium_104                RIGAPASWTAAVDAQQQSHGRFLAATDDEILAAYHLVAESEGVFVEPASA
MSMEG_4956|M.smegmatis_MC2_155      RIGSPASWNSAVEAQQQSDGRFLAATDEEILAAYHLVARTEGVFVEPASA
MAB_1436|M.abscessus_ATCC_1997      RIGSPASWSGAVAAQQESGGKFLAVTDEEILNAYRLVASSEGVFVEPASA
                                    ***:****..** *:::* *:*:*.:* *** **: **  **********

Mflv_2299|M.gilvum_PYR-GCK          ASIAGLLKAIEEGWVAKGSTVVCTVTGNGLKDPDTALKGMPAVIPVPVDP
Mvan_4347|M.vanbaalenii_PYR-1       ASIAGLLKSIEDGWVAKGSTVVCTVTGNGLKDPDTALKGMPAVIPVPVDP
TH_2003|M.thermoresistible__bu      ASIAGLFKAVEDGWVARGSTVVCTVTGNGLKDPDTALRDMPTVTPVPVDP
Mb1327|M.bovis_AF2122/97            ASIAGLLKAIDDGWVARGSTVVCTVTGNGLKDPDTALKDMPSVSPVPVDP
Rv1295|M.tuberculosis_H37Rv         ASIAGLLKAIDDGWVARGSTVVCTVTGNGLKDPDTALKDMPSVSPVPVDP
MLBr_01130|M.leprae_Br4923          ASIAGLLKAIDGGWVARGSTVVCTITGNGLKDPDTALKDMPSVSPVPVDA
MMAR_4102|M.marinum_M               ASIAGLLKAIDDGWVARGSTVVCTVTGNGLKDPDTALKDMPKVSPVPVDP
MUL_3969|M.ulcerans_Agy99           ASIAGLLKAIDDGWVARGSTVVCTVTGNGLKDPDTALKDMPKVSPVPVDP
MAV_1510|M.avium_104                ASIAGLLKAVEDGWVARGSTVVCTVTGNGLKDPDTALRDMPTVTPLPVDP
MSMEG_4956|M.smegmatis_MC2_155      ASIAGLLKSVEDGWVKRGSTVVCTVTGNGLKDPDTALKGMPQVTPVPVDP
MAB_1436|M.abscessus_ATCC_1997      ASIAGLLKSVADGWVAKGSTVVCTVTGNGLKDPDNALSGMPEVTPIPVQA
                                    ******:*::  *** :*******:*********.** .** * *:**:.

Mflv_2299|M.gilvum_PYR-GCK          VAVVAKLGLV
Mvan_4347|M.vanbaalenii_PYR-1       VAVVAKLGLV
TH_2003|M.thermoresistible__bu      VAVVEQLGLD
Mb1327|M.bovis_AF2122/97            VAVVEKLGLA
Rv1295|M.tuberculosis_H37Rv         VAVVEKLGLA
MLBr_01130|M.leprae_Br4923          VAVVEQLGLV
MMAR_4102|M.marinum_M               VAVVEKLGLA
MUL_3969|M.ulcerans_Agy99           IAVVEKLGLA
MAV_1510|M.avium_104                VLVVEKLGLA
MSMEG_4956|M.smegmatis_MC2_155      SAVVAELGLS
MAB_1436|M.abscessus_ATCC_1997      SAVAEALELA
                                      *.  * *

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_2003	thrC	-	100% (361)	PROBABLE THREONINE SYNTHASE THRC
M. thermoresistible (build 8)	TH_1800	ilvA	1e-17	28.66% (307)	Probable threonine dehydratase ilvA
M. thermoresistible (build 8)	TH_1075	trpB	1e-09	22.54% (346)	Probable tryptophan synthase, beta subunit trpB