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M. thermoresistible (build 8) TH_1800 (ilvA)

annotation: Probable threonine dehydratase ilvA
coordinates: 3516267 - 3517580
length: 438

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1800ilvA-100% (438)Probable threonine dehydratase ilvA
M. thermoresistible (build 8)TH_2003thrC1e-1728.66% (307) PROBABLE THREONINE SYNTHASE THRC
M. thermoresistible (build 8)TH_1075trpB5e-1226.43% (333) Probable tryptophan synthase, beta subunit trpB

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1585ilvA0.082.57% (436) threonine dehydratase
M. gilvum PYR-GCKMflv_3634-0.079.18% (437) threonine dehydratase
M. tuberculosis H37RvRv1559ilvA0.082.57% (436) threonine dehydratase
M. leprae Br4923MLBr_01209ilvA0.080.29% (421) threonine dehydratase
M. abscessus ATCC 19977MAB_2691c-1e-17272.77% (426) threonine dehydratase
M. marinum MMMAR_2374ilvA0.080.28% (436) threonine dehydratase IlvA
M. avium 104MAV_3217ilvA0.081.65% (436) threonine dehydratase
M. smegmatis MC2 155MSMEG_3183ilvA0.084.16% (423) threonine dehydratase
M. ulcerans Agy99MUL_1550ilvA0.079.82% (436) threonine dehydratase
M. vanbaalenii PYR-1Mvan_2783-0.078.49% (437) threonine dehydratase

CLUSTAL 2.0.9 multiple sequence alignment


TH_1800|M.thermoresistible__bu      VTADLTHSLRRSDQ-SPLSAADIDEAAARLAGVVTRTPLQFCDRLSEATG
MSMEG_3183|M.smegmatis_MC2_155      MTTELSADSRITALTAPLSAADIDEAARRISGVVTESPLQYCERLSEATG
Mb1585|M.bovis_AF2122/97            MSAELSQSPSSSPL-FSLSGADIDRAAKRIAPVVTPTPLQPSDRLSAITG
Rv1559|M.tuberculosis_H37Rv         MSAELSQSPSSSPL-FSLSGADIDRAAKRIAPVVTPTPLQPSDRLSAITG
MMAR_2374|M.marinum_M               MSAELSQTPSRSP----LSAADIDNAAERIAPVITPTPLQLCERLSDITG
MUL_1550|M.ulcerans_Agy99           MSAELSQTPSRSP----LSAADIDNAAERIAPVITPTPLQLCERLSDITG
MLBr_01209|M.leprae_Br4923          MSAEPSRNPRTPP----VSAVDIDGAAKRIAPVVTPTPLQLSDRLSAITG
MAV_3217|M.avium_104                MSAELSQSPSVAP----LSAADIDDAAKRIAAVVTPTPLQFSDRLSAITG
Mflv_3634|M.gilvum_PYR-GCK          MSAELSQSPRIDPA-TPLRAADIDEAAQRISGLVSRTPLQFCDRLSEITG
Mvan_2783|M.vanbaalenii_PYR-1       MSTELSQTPRIDPA-APLRAADIDEAARRISGVVSKTPLQFSDRLSAITG
MAB_2691c|M.abscessus_ATCC_199      ----MSTSEVVT-------AADIDAAAKRIDEVVHPTPLQHADRLSALTR
                                         :             ..*** ** *:  ::  :*** .:***  * 

TH_1800|M.thermoresistible__bu      ANIYLKREDLQAVRSYKLRGAYNLLSQLTEEEKAAGVVCSSAGNHAQGFA
MSMEG_3183|M.smegmatis_MC2_155      ANVYLKREDLQAVRSYKVRGAFNLMAQLSAEELAAGVVCSSAGNHAQGFA
Mb1585|M.bovis_AF2122/97            ATVYLKREDLQTVRSYKLRGAYNLLVQLSDEELAAGVVCSSAGNHAQGFA
Rv1559|M.tuberculosis_H37Rv         ATVYLKREDLQTVRSYKLRGAYNLLVQLSDEELAAGVVCSSAGNHAQGFA
MMAR_2374|M.marinum_M               ATVYLKREDLQIVRSYKLRGAYNLLVQLTAEELAAGVVCSSAGNHAQGFA
MUL_1550|M.ulcerans_Agy99           ATVYLKREDLQIVRSYKLRGAYNLLVQLTAEELAAGVVCSSAGNHAQGFA
MLBr_01209|M.leprae_Br4923          AAVYLKREDLQTVRSYKLRGAYNLLVQLTDEEIAAGVVCSSAGNHAQGVA
MAV_3217|M.avium_104                AQVYLKREDLQIVRSYKLRGAYNLLVQLSETELAAGVVCSSAGNHAQGFA
Mflv_3634|M.gilvum_PYR-GCK          ATVYLKREDLQAVRSYKLRGAYNLLMQLTPEEKAAGVVCSSAGNHAQGFA
Mvan_2783|M.vanbaalenii_PYR-1       AQVYLKREDLQAVRSYKLRGAYNLLMQLSAEEKAAGVVCSSAGNHAQGFA
MAB_2691c|M.abscessus_ATCC_199      AEVYLKREDLQSVRSYKVRGAFNLLMQLSDEEKAAGVVCSSAGNHAQGFA
                                    * :******** *****:***:**: **:  * ***************.*

TH_1800|M.thermoresistible__bu      LACRMMGIHGRIYIPAKTPKQKRQRIRYHGREFIELIAVGRTYDLAAAAA
MSMEG_3183|M.smegmatis_MC2_155      MACRTMKTHGRVYVPAKTPKQKRDRIRYHGREFIELIAVGATYDLAAAAA
Mb1585|M.bovis_AF2122/97            YACRCLGVHGRVYVPAKTPKQKRDRIRYHGGEFIDLIVGGSTYDLAAAAA
Rv1559|M.tuberculosis_H37Rv         YACRCLGVHGRVYVPAKTPKQKRDRIRYHGGEFIDLIVGGSTYDLAAAAA
MMAR_2374|M.marinum_M               FACKTLGVHGRVYVPAKTPKQKRDRIRYHGGEFIDLIVGGETYDLAAAAA
MUL_1550|M.ulcerans_Agy99           FACKTLGVRGRVYVPAKTPKQKRDRIRYHGGEFIDLIVGGETYDLAAAAA
MLBr_01209|M.leprae_Br4923          YACRSLGVHGRVYVPAKTPKQKWDRIRYHGGAFIELIVGRSTYDLAAAAA
MAV_3217|M.avium_104                YACRMLQVHGRVYVPAKTPLQKRDRIRYHGGEFIELIVGGTTYDQAAEAA
Mflv_3634|M.gilvum_PYR-GCK          LACRSMGIHGRVYVPAKTPRQKRDRIRYHGGDFIELIVGGKTYDMAAQAA
Mvan_2783|M.vanbaalenii_PYR-1       LACRSMGVHGRVYVPAKTPKQKRNRIRYHGGDFIELIVGGKTYDLAAEAA
MAB_2691c|M.abscessus_ATCC_199      LACKSMGVHGRVYIPSKTPKQKRQRIIYHGNGFVELIAVGHGYDEAAAAA
                                     **: :  :**:*:*:*** ** :** ***  *::**.    ** ** **

TH_1800|M.thermoresistible__bu      LADVERTGATLVHPYDDPRTIAGQGTIATEILEQLDAEDGPGGGGEPDLV
MSMEG_3183|M.smegmatis_MC2_155      LEDVARTGATLVPPYDDLRTMAGQGTIAAELLDQLDT--------EPDLV
Mb1585|M.bovis_AF2122/97            LEDVERTGATLVPPFDDLRTIAGQGTIAVEVLGQLED--------EPDLV
Rv1559|M.tuberculosis_H37Rv         LEDVERTGATLVPPFDDLRTIAGQGTIAVEVLGQLED--------EPDLV
MMAR_2374|M.marinum_M               REDVERTGATLVPPYDDLRTMAGQGTIAVELLAELDA--------EPDLV
MUL_1550|M.ulcerans_Agy99           REDVERTGATLVPPYDDLRTMAGQGTIAVELLAELDA--------EPDLV
MLBr_01209|M.leprae_Br4923          VDDIERTGATLVPPYDDVRVIAGQGTIAVELLEQLNT--------EPDLV
MAV_3217|M.avium_104                LADVASTGATLVPPYDDLRTIAGQGTIAVELLDQLDT--------EPDLV
Mflv_3634|M.gilvum_PYR-GCK          LDDVARTGATLVPPYDDLRTMAGQGTIAVEILDELGS--------EPDLV
Mvan_2783|M.vanbaalenii_PYR-1       LDDVARTGATLVPPYDDLRTMAGQGTIAVEILDQLGQ--------EPDLV
MAB_2691c|M.abscessus_ATCC_199      KADAARTGATLVPAFDDVRTIAGQGTIAAEILDQLDS--------PPDVV
                                      *   ****** .:** *.:*******.*:* :*           **:*

TH_1800|M.thermoresistible__bu      IVPVGGGGCIAGITTYLAERTRNTAVLGVEPAGAASMMAALAAGEPVTLD
MSMEG_3183|M.smegmatis_MC2_155      IVPVGGGGCIAGITTYLAARTDNTSVLGVEPAGAASMIAALAAGEPVTLA
Mb1585|M.bovis_AF2122/97            VVPVGGGGCIAGITTYLAERTTNTAVLGVEPAGAAAMMAALAAGEPVTLD
Rv1559|M.tuberculosis_H37Rv         VVPVGGGGCIAGITTYLAERTTNTAVLGVEPAGAAAMMAALAAGEPVTLD
MMAR_2374|M.marinum_M               VVPVGGGGCIAGITSYLAERTTKTAVLGIEPAGAAAMMAALAAGEPVTLD
MUL_1550|M.ulcerans_Agy99           VVPVGGGGCIAGITSYLAERTTKTAVLGIEPAGAAAMMAALAAGEPVTLD
MLBr_01209|M.leprae_Br4923          VVPVGGGGCIAGMTTYLAERTANTAVLGVEPAGAAAMMAALAAGEPVTLD
MAV_3217|M.avium_104                VVPVGGGGCIAGITTYLAERTDTTAVLGVEPAGAAAMMAALAAGEPVTLD
Mflv_3634|M.gilvum_PYR-GCK          VVPVGGGGCISGMTTYLAERTATTSVLGVEPAGAASFVAALANGTPVTLE
Mvan_2783|M.vanbaalenii_PYR-1       IVPVGGGGCISGMTTYLAERTATTSVMGVEPGGAAALVAALATGEPVTLE
MAB_2691c|M.abscessus_ATCC_199      VVPVGGGGCISGIVTYLRERAPEVRVVGVEPAGAACMAAALRAGGPVPLD
                                    :*********:*:.:**  *:  . *:*:**.***.: ***  * **.* 

TH_1800|M.thermoresistible__bu      HVDQFVDGAAVNRAGTYTHAALAAAGDMVSITTVDEGAVCTAMLDLYQNE
MSMEG_3183|M.smegmatis_MC2_155      DVDQFVDGAAVARAGQKPFEALAAAGDMVSLTTVDEGAVCTAMLDLYQNE
Mb1585|M.bovis_AF2122/97            HVDQFVDGAAVNRAGTLTYAALAAAGDMVSLTTVDEGAVCTAMLDLYQNE
Rv1559|M.tuberculosis_H37Rv         HVDQFVDGAAVNRAGTLTYAALAAAGDMVSLTTVDEGAVCTAMLDLYQNE
MMAR_2374|M.marinum_M               HVDQFVDGAAVNRAGTLPYAALSAAGDMVSITTVDEGAVCTAMLDLYQHE
MUL_1550|M.ulcerans_Agy99           HVDQFVDGAAVNRAGALPYAALSAAGDMVSITTVDEGAVCTAMLDLYQHE
MLBr_01209|M.leprae_Br4923          YVDQFVDGAAVNRVGTLPYAALTAAGDMVSITTVDEGAVCTAMLDLYQNE
MAV_3217|M.avium_104                HVDQFVDGAAVRRAGDLTYAALAAAGDMVSITTVDEGAVCTAMLDLYQNE
Mflv_3634|M.gilvum_PYR-GCK          HVDQFVDGAAVARAGAKPFEALRAAGDMVSMTTVDEGAVCTAMLGLYQNE
Mvan_2783|M.vanbaalenii_PYR-1       TVDQFVDGAAVARVGALPFAALSAAGDMVSITTVDEGAVCTAMLDLYQNE
MAB_2691c|M.abscessus_ATCC_199      HVDPFVDGCAVQVAGAAPYRVLAAAGEMLTLTTVDEGAACTAMLELYQNE
                                     ** ****.**  .*  .. .* ***:*:::*******.***** ***:*

TH_1800|M.thermoresistible__bu      GIIAEPAGALAVTGLSEAEIEPGSTVVCLISGGNNDVSRYNEVLERSLVH
MSMEG_3183|M.smegmatis_MC2_155      GIIAEPAGALSVAALLEADIEPGSTVVCLISGGNNDVSRYNEVLERSLVH
Mb1585|M.bovis_AF2122/97            GIIAEPAGALSVAGLLEADIEPGSTVVCLISGGNNDVSRYGEVLERSLVH
Rv1559|M.tuberculosis_H37Rv         GIIAEPAGALSVAGLLEADIEPGSTVVCLISGGNNDVSRYGEVLERSLVH
MMAR_2374|M.marinum_M               GIIAEPAGALSVAGLLEADIEPGSTVVCLISGGNNDVSRYGEILERSLVH
MUL_1550|M.ulcerans_Agy99           GIIAEPAGALSVAGLLEADIEPGSTVVCLISGGNNDVSRYGEILERSLVH
MLBr_01209|M.leprae_Br4923          GIIAEPAGALSVAGLLETDIEPGSTVVCLISGGNNDVLRYGEVLERSLIH
MAV_3217|M.avium_104                GIIAEPAGALSVTGLLEADIEPGSTVVCLISGGNNDVSRYGEVLERSLVH
Mflv_3634|M.gilvum_PYR-GCK          GIIAEPAGALSVAALLDADIEPGSTVVCLISGGNNDVSRYGEVLERSLVH
Mvan_2783|M.vanbaalenii_PYR-1       GIIAEPAGALSVAALLDSDIEPGSTVVCLISGGNNDVSRYGEVLERSLVH
MAB_2691c|M.abscessus_ATCC_199      GIIAEPAGALSVAALAEMAIEPGATVVCLISGGNNDVSRYGEILERSLVH
                                    **********:*:.* :  ****:************* **.*:*****:*

TH_1800|M.thermoresistible__bu      LGLKHYFLVDFPQEPGSLRRFLDEVLGEGDDITLFEYVKRNNRETGEALV
MSMEG_3183|M.smegmatis_MC2_155      LGLKHYFLVDFPQEPGALRRFLDEVLGPGDDITLFEYVKRNNRETGEALV
Mb1585|M.bovis_AF2122/97            LGLKHYFLVDFPQEPGALRRFLDDVLGPNDDITLFEYVKRNNRETGEALV
Rv1559|M.tuberculosis_H37Rv         LGLKHYFLVDFPQEPGALRRFLDDVLGPNDDITLFEYVKRNNRETGEALV
MMAR_2374|M.marinum_M               LGLKHYFLVDFPQEPGALRRFLDEVLGPNDDITLFEYVKRNNRETGEALV
MUL_1550|M.ulcerans_Agy99           LGLKHYFLVDFPQEPGALRRFLDEVLGPNDDITLFEYVKRNNRETGEALV
MLBr_01209|M.leprae_Br4923          LGLKHYFLVDFPQKPGALRRFLDEVLGPNDDITLFEYVKRNNRETGEALV
MAV_3217|M.avium_104                LGLKHYFLVDFPQEPGALRRFLDEVLGPNDDITLFEYVKRNNRETGEALV
Mflv_3634|M.gilvum_PYR-GCK          LGLKHYFLVDFPQEPGALRRFLDEVLGPNDDITLFEYVKRNNRETGEALV
Mvan_2783|M.vanbaalenii_PYR-1       LGLKHYFLVDFPQEPGALRRFLDEVLGPNDDITLFEYVKRNNRETGEALV
MAB_2691c|M.abscessus_ATCC_199      LGLKHYFLVDFPQEPGALRRFLGEVLGPNDDITLFEYVKRNNREMGAALV
                                    *************:**:*****.:*** .*************** * ***

TH_1800|M.thermoresistible__bu      GIELSSAADLDGLLARMEASDIHVERLEPGSPAYRYLT-
MSMEG_3183|M.smegmatis_MC2_155      GVELSSAADLEGLLARMGQSDIHVELLEPGSPTYRYLT-
Mb1585|M.bovis_AF2122/97            GIELGSAADLDGLLARMRATDIHVEALEPGSPAYRYLL-
Rv1559|M.tuberculosis_H37Rv         GIELGSAADLDGLLARMRATDIHVEALEPGSPAYRYLL-
MMAR_2374|M.marinum_M               GVELGSAANLDGLLARMHETEVHVEPLAPGSPAYRYLL-
MUL_1550|M.ulcerans_Agy99           GVELGSAANLDGLLARMRETEVHVEPLAPGSPAYRYLL-
MLBr_01209|M.leprae_Br4923          GIQLGSAVDLDVLLARMQGTEMHVETLQPGSPAYRYLLL
MAV_3217|M.avium_104                GIQLGSSADLDGLLARMRATELHVETLKPGSPAYRYLLL
Mflv_3634|M.gilvum_PYR-GCK          GIEMANASDLDGLLARMQSSECHIELLEPGSPTYRYLT-
Mvan_2783|M.vanbaalenii_PYR-1       GIEMGSASDLEGLLARMQTSECHVELLEPGSPTYRYLT-
MAB_2691c|M.abscessus_ATCC_199      GIELSYADDLSGLLDRMRFSGLDIERLEPDSPAFRYLT-
                                    *:::. : :*. ** **  :  .:* * *.**::***