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M. thermoresistible (build 8) TH_1657 (fadE36)

annotation: POSSIBLE ACYL-CoA DEHYDROGENASE FADE36
coordinates: 3218356 - 3219384
length: 343

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1657fadE36-100% (343)POSSIBLE ACYL-CoA DEHYDROGENASE FADE36
M. thermoresistible (build 8)TH_2763-1e-4135.69% (297) PUTATIVE putative aminoglycoside phosphotransferase
M. thermoresistible (build 8)TH_3925-9e-3332.27% (313) PUTATIVE putative acyl-CoA dehydrogenase FadE36_1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3787cfadE361e-13568.91% (341) acyl-CoA dehydrogenase
M. gilvum PYR-GCKMflv_1204-1e-14475.52% (339) aminoglycoside phosphotransferase
M. tuberculosis H37RvRv3761cfadE361e-13568.91% (341) acyl-CoA dehydrogenase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4589c-2e-4034.95% (309) putative phosphotransferase
M. marinum MMMAR_5304fadE361e-13268.62% (341) acyl-CoA dehydrogenase FadE36
M. avium 104MAV_0316-1e-13068.53% (340) phosphotransferase enzyme family protein
M. smegmatis MC2 155MSMEG_6337-1e-14976.04% (338) phosphotransferase enzyme family protein
M. ulcerans Agy99MUL_4942fadE36_16e-4836.39% (338) acyl-CoA dehydrogenase FadE36_1
M. vanbaalenii PYR-1Mvan_5603-1e-15781.07% (338) aminoglycoside phosphotransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3787c|M.bovis_AF2122/97           ---------MTSVDRLDGLDLGALDRYLRSLG-IGRDGELRGELISGGRS
Rv3761c|M.tuberculosis_H37Rv        ---------MTSVDRLDGLDLGALDRYLRSLG-IGRDGELRGELISGGRS
MMAR_5304|M.marinum_M               ---------MTSVDRLDGLDLAALDGYLRSLG-LGREGELRGELISGGRS
MAV_0316|M.avium_104                ---------MTSADQLEGLDLAALDSYLRSLG-IGRDGELRAEFISGGRS
Mflv_1204|M.gilvum_PYR-GCK          ------------MTELEGLDLAALDRHLREVG-VPRSGELRAELIAGGRS
Mvan_5603|M.vanbaalenii_PYR-1       ------------MTELEGLDLAALDRHLCDVG-VPRSGELRAEFISGGRS
TH_1657|M.thermoresistible__bu      ----------MAVTSLDGLDLDALDRHLRQVG-VPRSGELRAELIAGGRS
MSMEG_6337|M.smegmatis_MC2_155      ------------MTSLEGLDLDALDRHLRAEG-IARAGDLRAELIAGGRS
MUL_4942|M.ulcerans_Agy99           -----------MSEDIPGVHAHAVSRWLVTLG-HQVAAPLRFQRIGLGQA
MAB_4589c|M.abscessus_ATCC_199      MHKDVSSDSDGPTGDAASLDADAIPTSLSEYLNRELGEQVSVRRLSAGHS
                                                     .:.  *:   *           :  . :. *::

Mb3787c|M.bovis_AF2122/97           NLTFRVYDDA-SSWLVRRPPLHGLTPSAHDMAREYRVVAALGDTPVPVAR
Rv3761c|M.tuberculosis_H37Rv        NLTFRVYDDA-SSWLVRRPPLHGLTPSAHDMAREYRVVAALGDTPVPVAR
MMAR_5304|M.marinum_M               NLTFRVYDDA-TSWLVRRPPLHGLTPSAHDMAREYRVVAALQDTPVPVAR
MAV_0316|M.avium_104                NLTFRVYDDA-TSWLVRRPPLHGLTPSAHDMAREYRVVAALQDTPVPVAR
Mflv_1204|M.gilvum_PYR-GCK          NLTFLVGDDA-SEWVLRRPPLHGLTPSAHDMAREYKVVAALAGTKVPVAR
Mvan_5603|M.vanbaalenii_PYR-1       NLTFLVFDDA-SKWVLRRPPLHGLTPSAHDMAREYRVVAALADTAVPVAR
TH_1657|M.thermoresistible__bu      NLTFLVFDDQ-SRWVLRRPPLHGLTPSAHDMAREYRVVAALADTPVPVAR
MSMEG_6337|M.smegmatis_MC2_155      NLTFLVFDDA-SKWVLRRPPLHGLTPSAHDMAREYRVVAALAGTPVPVAR
MUL_4942|M.ulcerans_Agy99           NLTYRVTDAAGRAWVLRHPPLGHLLASAHDVVREARIMAALAETDVPVPR
MAB_4589c|M.abscessus_ATCC_199      NLTYVVTGSSGTQWILRRPPFGRLQAGAHDVMREYRVLDALSTAQVRVPR
                                    ***: * .     *::*:**:  * ..***: ** ::: **  : * *.*

Mb3787c|M.bovis_AF2122/97           TISLCQDDSVLGAPFQVVEFVAGQVVRRRAELEALGSRSVIEGCVDALIR
Rv3761c|M.tuberculosis_H37Rv        TISLCQDDSVLGAPFQVVEFVAGQVVRRRAELEALGSRSVIEGCVDALIR
MMAR_5304|M.marinum_M               AIALCEDDTVLGAPFQIVEFVAGQVVRRRAQLEVLGSR-AIDGCVDSLIR
MAV_0316|M.avium_104                TIGLCEDESVLGAPFQIVEFVAGQVVRRRAQLESFSHT-VIEGCVDSLIR
Mflv_1204|M.gilvum_PYR-GCK          AVTMSDDDSVLGAPFQMVERVAGLVVRHTPQLAALGDETVISNVVDSLIQ
Mvan_5603|M.vanbaalenii_PYR-1       AVTMRNDDSVLGAPFQMVEYVAGRVVRHTDQLAALGDRATIEKCVDALIK
TH_1657|M.thermoresistible__bu      AVTMSNDDSVLGAPFQMVEHVPGLVVRYTDDLKSVGDRDAIEACVDSLIR
MSMEG_6337|M.smegmatis_MC2_155      AVTMRNDDSVLGAPFQMVDHVDGRVVRTAAELAALGDQTVIDNCIDALIK
MUL_4942|M.ulcerans_Agy99           ILGVTTDSEFSEAPLVLMEFVDGLVVDTMEVAEALTPR-QRRQIALSLPR
MAB_4589c|M.abscessus_ATCC_199      VTLASTDAEIFGAPFYLMERQDGEVIRDVSPEWFVGSA--RRELVLDLAV
                                          *  .  **: :::   * *:        .            *  

Mb3787c|M.bovis_AF2122/97           VLVDLHSIDPKAVGLSDFGKPDGYLERQVRRWGSQWELVR-LPDDHRDAD
Rv3761c|M.tuberculosis_H37Rv        VLVDLHSIDPKAVGLSDFGKPDGYLERQVRRWGSQWELVR-LPDDHRDAD
MMAR_5304|M.marinum_M               VLVDLHSIDPGAVGLGDFGKPDGYLQRQVRRWGSQWDLVR-LPDDRRDGD
MAV_0316|M.avium_104                VLVDLHSVDPDAVGLADFGKPSGYLERQVRRWGSQWALVR-LPEDRRDAD
Mflv_1204|M.gilvum_PYR-GCK          VLADLHEVDPESVGLGDFGKASGYLERQVRRWGSQWDLVK-RDDDPSDAD
Mvan_5603|M.vanbaalenii_PYR-1       VLADLHSVDPDAVGLSDFGKPSGYLERQVRRWGSQWDLVR-RADDPCDAD
TH_1657|M.thermoresistible__bu      VLADLHAVDYEAVGLGDFGKPSGYLERQVRRWASQWELVK-HPDDARDGD
MSMEG_6337|M.smegmatis_MC2_155      ALSDLHAVDPYAVGLGDFGKPDGYLERQVRRWGSQWEHVR-LPDDARDDD
MUL_4942|M.ulcerans_Agy99           TLAKIHAVDLAKVGLDDLASHKPYAQRQLKRWAGQWELSK-TRELP---E
MAB_4589c|M.abscessus_ATCC_199      ALAEIHNADPTRLVEAKLGRESGYLARQLKTWGGQWESIKELPTGRDLQD
                                    .* .:*  *   :   .:.  . *  **:: *..**   :         :

Mb3787c|M.bovis_AF2122/97           ISRLHLALQQAIPQQSRTSIVHGDYRIDNTILDTDDPCHVRAVVDWELST
Rv3761c|M.tuberculosis_H37Rv        ISRLHLALQQAIPQQSRTSIVHGDYRIDNTILDTDDPCHVRAVVDWELST
MMAR_5304|M.marinum_M               VARLHSALQQAIPTQSRTSIVHGDYRIDNTILDADDPTRVRAVVDWELST
MAV_0316|M.avium_104                VERLHSGLGQAIPQQSRTSIVHGDYRIDNTILDADDPTKVRAVVDWELST
Mflv_1204|M.gilvum_PYR-GCK          VRKLHQRLAESVPEQSRASIVHGDYRIDNTILDADDPTKVAAVLDWEMST
Mvan_5603|M.vanbaalenii_PYR-1       VRRLHERLSAALPPQSRSSIVHGDYRIDNTILDAEDPTKVVAVLDWEMST
TH_1657|M.thermoresistible__bu      VKKLHARLEQAVPPQSRTSIVHGDYRIDNTILDADDPTEVVAVLDWEMST
MSMEG_6337|M.smegmatis_MC2_155      VRRLHAALADAVPPQSGTSIVHGDYRIDNTVLDAEDATVVRAVLDWEMST
MUL_4942|M.ulcerans_Agy99           LDDLTRRLVAAAPEQREISLVHGDFHLRN-LITSPETGAVVATLDWELST
MAB_4589c|M.abscessus_ATCC_199      HTTITAWLTENYPGDRPAAVVHGDYKLDNVLVDP-ATARITAVLDWEMAT
                                       :   *    * :   ::****::: * :: .  .  : *.:***::*

Mb3787c|M.bovis_AF2122/97           LGDPLSDAALMCVYRDPALDLIVHAQAA---WTSPLLPAADELADRYSLV
Rv3761c|M.tuberculosis_H37Rv        LGDPLSDAALMCVYRDPALDLIVHAQAA---WTSPLLPAADELADRYSLV
MMAR_5304|M.marinum_M               LGDPLSDAALMCVYRDPALDLIVNTQAA---WTSPLLPTADELADRYSLV
MAV_0316|M.avium_104                LGDPLSDAALMCVYRDPALDLIVNAQAA---WTSPLLPTADELADRYSLV
Mflv_1204|M.gilvum_PYR-GCK          LGDPLSDAALMCVYRLPAFN-EVHDDAA---WACDLMPPTDDLAQRYALA
Mvan_5603|M.vanbaalenii_PYR-1       LGDPLSDAALMCVYRHPMFN-MVHADAA---WASELIPDADALADKYSRA
TH_1657|M.thermoresistible__bu      LGDPLSDAALMCVYRHPTFN-YVHSDAA---WASELIPSADALAEKYSTA
MSMEG_6337|M.smegmatis_MC2_155      LGDPLSDAALMCVYRNPMFG-HIHTDAA---WSSDLVPPADELADRYSKV
MUL_4942|M.ulcerans_Agy99           LGDPLADMGSLLTYWMEPGESGVGDFAP---STLDGFPDRAEMTRLYLEE
MAB_4589c|M.abscessus_ATCC_199      VGDPLADLGYLLYMTPEPGGEVAMSELTGSVTAQEGCPSHTEIAQAYREA
                                    :****:* . :                .    :    *    ::  *   

Mb3787c|M.bovis_AF2122/97           SGQPLGHWE-----FYMALAYFKLAIIAAGIDYRRRMSEQAEGKDTAAES
Rv3761c|M.tuberculosis_H37Rv        SGQPLGHWE-----FYMALAYFKLAIIAAGIDYRRRMSEQAEGKDTAAES
MMAR_5304|M.marinum_M               SGMSLGHWE-----FYMALAYFKLAIIAAGIDFRRRMSELADGKTDASDE
MAV_0316|M.avium_104                AGIPLAHWE-----FYMALAYFKLAIIAAGIDFRRRMSDQARGLGEAAEH
Mflv_1204|M.gilvum_PYR-GCK          SGKPLDHWD-----FYMALGYFKIAIIAAGIAYRARMGGGV---AEGTDE
Mvan_5603|M.vanbaalenii_PYR-1       AGQPLDHWD-----FYMALAYFKLAIIGAGIAYRAREAG-V---VDDTDK
TH_1657|M.thermoresistible__bu      AGQDLVHWD-----FYMALAYFKLAIIAAGIDYRARESG-A---GGSTDR
MSMEG_6337|M.smegmatis_MC2_155      SGRDLAHWD-----FYMALAYFKLAIIAAGIDYRRREGA------DGPEQ
MUL_4942|M.ulcerans_Agy99           TGRDPAALQ-----YWHVLGLWKLAIIAEGVMRRAMDEPQNKASEGTPTV
MAB_4589c|M.abscessus_ATCC_199      RSGDQSYWTPEDLVYYQVLGGWKLATLLE-VSYQRHLAGTTDDPFFAELD
                                     .            :: .*. :*:* :   :  :                

Mb3787c|M.bovis_AF2122/97           VPDVVAPLIARGLAEIAKKSG------
Rv3761c|M.tuberculosis_H37Rv        VPDVVAPLIARGLAEIAKKSG------
MMAR_5304|M.marinum_M               APEVVSPLISRGLAEIAKPVS------
MAV_0316|M.avium_104                TPEVVAPLISRGLAELAKLPG------
Mflv_1204|M.gilvum_PYR-GCK          VDRAVRPFVAAGLHILS----------
Mvan_5603|M.vanbaalenii_PYR-1       VGEAVAPLIAAGLSQLA----------
TH_1657|M.thermoresistible__bu      VGEAVAPLIDAGLRTLRA---------
MSMEG_6337|M.smegmatis_MC2_155      VGEAVAPMIAAGLAALG----------
MUL_4942|M.ulcerans_Agy99           AWIDARVHMAREIADAAGMNQVSDSAF
MAB_4589c|M.abscessus_ATCC_199      EGVPRLLSVARSLIPAAG---------
                                            :   :