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M. thermoresistible (build 8) TH_1547 (-)

annotation: secreted protein
coordinates: 2919978 - 2922218
length: 747

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1547--100% (747)secreted protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_5160-0.066.88% (782) secreted protein
M. tuberculosis H37RvRv2048cpks123e-0525.10% (514) polyketide synthase pks12
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104-----
M. smegmatis MC2 155MSMEG_1313-0.065.49% (791) secreted protein
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_1155-0.065.53% (789) secreted protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        MVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGGV
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        DSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKSYARTGGFV
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        DGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSA
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        TGVFAGLIVGGYGMLAEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVD
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        TACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFSRHRGLAP
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        DGRCKPYAGRADGVGWSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQD
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        GASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEA
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        QALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHEL
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        LPATLHVDVPSPHVDWSAGAVELLTAPRVWPAGARTRRAGVSSFGISGTN
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        AHVIIEAVPVVPRREAGWAGPVVPWVVSAKSESALRGQAARLAAYVRGDD
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        GLDVADVGWSLAGRSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVVRG
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        TATAAGKTVFVFPGQGSQWLGMGIELLDTAPAFAQQIDACAEAFAEFVDW
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        SLVDVLRGAPGAPGLDRVDVVQPVLFAVMVSLAELWKSVAVHPDAVIGHS
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        QGEIAAAYVAGALSLRDAARVVTLRSKLLAGLAGPGGMVSIACGADQARD
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        LLAPFGDRVSIAVVNGPSAVVVSGEVGALEELIAVCSTKELRTRRIEVDY
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        ASHSVEVEAIRGPLAEALSGIEPRSTRTVFFSTVTGNRLDTAGLDADYWY
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        RNVRQTVLFDQAVRNACEQGYRTFIESSPHPALITGVEETFAACTDGDSE
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        AIVVPTLGRGDGGLHRFLLSAASAFVAGVAVNWRGTLDGAGYVELPTYAF
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        DKRRFWLSAEGSGADVSGLGLGASEHPLLGAVVDLPASGGVVLTGRLSPN
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        VQPWLADHAVSDVVLFPGTGFVELAIRAGDEVGCSVLDELTLAAPLLLPA
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        TGSVAVQVVVDAGRDSNSRGVSIFSRADAQAGWLLHAEGILRPGSVEPGA
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        DLSVWPPAGAVTVDVADGYERLATRGYRYGPAFRGLTAMWARGEEIFAEV
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        RLPEAAGGVGGFGVHPALLDAVLHAVVIAGDPDELALPFAWQGVSLHATG
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        ASAVRARIAPAGPSAVSVELADGLGLPVLSVASMVARPVTERQLLAAVSG
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        SGPDRLFEVIWSPASAATSPGPTPAYQIFESVAADQDPVAGSYVRSHQAL
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        AAVQSWLTDHESGVLVVATRGAMALPREDVADLAGAAVWGLVRSAQTEHP
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        GRIVLVDSDAATDDAAIAMALATGEPQVVLRGGQVYTARVRGSRAADAIL
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        VPPGDGPWRLGLGSAGTFENLRLEPVPNADAPLGPGQVRVAMRAIAANFR
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        DIMITLGMFTHDALLGGEGAGVVVEVGPGVTEFSVGDSVFGFFPDGSGTL
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        VAGDVRLLLPMPADWSYAEAAAISAVFTTAYYAFIHLADVQPGQRVLIHA
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        GTGGVGMAAVQLARHLGLEVFATASKGKWDTLRAMGFDDDHISDSRSLEF
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        EDKFRAATGGRGFDVVLDSLAGEFVDASLRLVAPGGVFLEMGKTDIRDPG
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        VIAQQYPGVRYRAFDLFEPGRPRMHQYMLELATLFGDGVLRPLPVTTFDV
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        RRAPAALRYLSQARHTGKVVMLMPGSWAAGTVLITGGTGMAGSAVARHVV
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        ARHGVRNLVLVSRRGPDAPGAAELVAELAAAGAQVQVVACDAADRAALAK
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        VIADIPVQHPLSGVIHTAGALDDAVVMSLTPDRVDVVLRSKVDAAWHLHE
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        LTRDLDVSAFVMFSSMAGLVGSSGQANYAAANSFLDALAAHRRAHGLPAI
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        SLGWGLWDQASAMTGGLDAADLARLGREGVLALSTAEALELFDTAMIVDE
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        PFLAPARIDLTALRAHAVAVPPMFSDLASAPTRRQVDDSVAAAKSKSALA
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        HRLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQDLGFDSLT
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        AVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIRTELAGLPQEIKHTPA
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        VRTTSEDPIAIVGMACRYPGGVNSPDDMWDMLIQGRDVLSEFPADRGWDL
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        AGLYNPDPDAAGACYTRTGGFVDGVGDFDPAFFGVGPSEALAMDPQHRML
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        LELSWEALERAGIDPTGLRGSATGVFAGVMTQGYGMFAAEPVEGFRLTGQ
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        LSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHMAVGSLRSGECDLALA
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        GGVTVNATPDIFVEFSRWRGLSPDGRCKAFAAAADGTGFSEGGGMLVLQR
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        LSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGL
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------MAVHWT
Mvan_1155|M.vanbaalenii_PYR-1       -----------------------------------------------MTA
MSMEG_1313|M.smegmatis_MC2_155      ---------------------------------------------MTWMS
TH_1547|M.thermoresistible__bu      ----------------------------------------------VQIF
Rv2048c|M.tuberculosis_H37Rv        SAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNM
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          PNWTCATATGLTATLLLAG------CSRGPDDEGAT-PIRER--ATAAVD
Mvan_1155|M.vanbaalenii_PYR-1       SHLARAMTTAAIAALLLAA------CSTDTQDEAPA-ESTDTPKATSPID
MSMEG_1313|M.smegmatis_MC2_155      QPTARAAALTTLVALIAAG------CATE-KEPSRD-DASPGPRAISPID
TH_1547|M.thermoresistible__bu      RLSRTGLAVAGAVTMALTA------CSTADDHPRPDGDGADRVRATSTIE
Rv2048c|M.tuberculosis_H37Rv        GHTQAAAGVAGVIKMVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAP
                                         .        :  :       .:   .                .  

Mflv_5160|M.gilvum_PYR-GCK          FTLPDAQRYHRLATYPVHLN----------KPATDPVDAETVAEISTVTP
Mvan_1155|M.vanbaalenii_PYR-1       FNLPDAERFHRAATYPVYLN----------RPAGEDPAAETVAEISTVTP
MSMEG_1313|M.smegmatis_MC2_155      WNLPAAERYHRTATYPVFLN----------RPADDPVDAETVAEISTVTP
TH_1547|M.thermoresistible__bu      WVPPPDQRYHRLATFPVYLN----------RPDGEAADTETVAEISTVTP
Rv2048c|M.tuberculosis_H37Rv        RVWPAGARTRRAGVSSFGISGTNAHVIIEAVPVVPRREAGWAGPVVPWVV
                                       *   * :* .. .. :.           *      :  .. : . . 

Mflv_5160|M.gilvum_PYR-GCK          DGNTVIYTDAAGKRIGFLDIRDPANPVGLGTLSLAELGHADDQPTSVAAV
Mvan_1155|M.vanbaalenii_PYR-1       DGNTLIYTDAAAKRIGFLDIRDAAKPVGLGTLSLEELGHADDQPTSVAAV
MSMEG_1313|M.smegmatis_MC2_155      DGNTLIYTDAAAKRIGFVDITDPANPAGKGTLSLKELGHQDDQPTSVAAV
TH_1547|M.thermoresistible__bu      DGGTVVYTDAAAKRIGFLDIRDPAAPVGVGTLSLTDLGPPTDSGPSTGPG
Rv2048c|M.tuberculosis_H37Rv        SAKSESALRGQAARLAAYVRGDDGLDVADVGWSLAGRSVFEHRAVVVGGD
                                    .. :     . . *:.     * .  ..    **   .   .    ..  

Mflv_5160|M.gilvum_PYR-GCK          GEYVLVVVDTTGGDFANPSGRVDVVRVADRTRVHSVDLGGQPDSIAVAHD
Mvan_1155|M.vanbaalenii_PYR-1       GEFVLVVVDTTGGDFTKPSGRVDVVRVADRTRVHSIDLGGQPDSIAIAGD
MSMEG_1313|M.smegmatis_MC2_155      GEFVLVVVDTTGGDFPHPSGRVDIVRVADRTRVHSIDLGGQPDSIAISPD
TH_1547|M.thermoresistible__bu      ----------SADDQPTSVAAVDEY------------------VLVVGPD
Rv2048c|M.tuberculosis_H37Rv        RDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQWLGMGMGLH
                                               ..*        .                     : :. .

Mflv_5160|M.gilvum_PYR-GCK          GSFAAIAIEN------------------QRDEEFTPPGAEEGDLPQPPTG
Mvan_1155|M.vanbaalenii_PYR-1       GSFAAIAMEN------------------QRDEEFTPPGAEEGDLPQPPTG
MSMEG_1313|M.smegmatis_MC2_155      GTFAAIAMEN------------------QRDEEFTPPGGEEGDLPQPPTG
TH_1547|M.thermoresistible__bu      GTLAAVAIEN------------------QRDEEFTPPGGQEGDLPQPPTG
Rv2048c|M.tuberculosis_H37Rv        AGYPVFAEAFNTVVGELDRHLLRPLREVMWGHDENLLNSTEFAQPALFAV
                                    .  ...*                       ..: .  .. *   *   : 

Mflv_5160|M.gilvum_PYR-GCK          FVQLLDLAGAPDTWVPRRVDFDVDAARAAGLDTPEDLEPEYVSVNARGQV
Mvan_1155|M.vanbaalenii_PYR-1       FLQLISLTGAPTGWTPRKVEFDVEAARAAGLDTPEDLEPEYVSINSRGQV
MSMEG_1313|M.smegmatis_MC2_155      FVQLIDLTGAPDTWTPRRSDFDVEAARAAGLDTPEDLEPEYVSINSRGQV
TH_1547|M.thermoresistible__bu      FVALIDLTGEPADWR-------------GGGGAPEDLEPEYVDINSRGQV
Rv2048c|M.tuberculosis_H37Rv        EVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLENAAVLVAARGRL
                                     : *: * *                   .      .**   * : :**::

Mflv_5160|M.gilvum_PYR-GCK          AVTLQENNGIAIIDGRTGAVQKISSAGTESVTG-----------------
Mvan_1155|M.vanbaalenii_PYR-1       AVTMQENNGIAIVDGRTGAVQKIFSAGTASVSG-----------------
MSMEG_1313|M.smegmatis_MC2_155      AVTLQENNGIAIIDGATGDVAKIFSAGSESVEG-----------------
TH_1547|M.thermoresistible__bu      AVSLQENNGFAVIDGVTGEVTGIFSAGTQSVAG-----------------
Rv2048c|M.tuberculosis_H37Rv        MQALPAGGAMVAVQAAEEEVRPLLSAEVDIAAVNGPASLVISGAQNAVAA
                                      ::  ...:. ::.    *  : **    .                   

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        VADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFAAVAAGIAIGRPTIGVI
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        SNVTGQLAGDDFGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFLEVGPSG
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          ------IDTAEDGGVEQTGSITDTPREPDAIG------------------
Mvan_1155|M.vanbaalenii_PYR-1       ------IDTAEDDTVDQTGSITDTPREPDSIG------------------
MSMEG_1313|M.smegmatis_MC2_155      ------IDTVEDDTIDQTGSILETPREPDAIG------------------
TH_1547|M.thermoresistible__bu      ------IDTTEDGVIDQSGSIGDTPREPDAIG------------------
Rv2048c|M.tuberculosis_H37Rv        GLVASIEESLPDVAVTTMSALRKDRPEPATLTNAVAQGFVTGMDLDWRAV
                                           ::  *  :   .:: .   ** ::                   

Mflv_5160|M.gilvum_PYR-GCK          -------------------WIDDTHVATANE-------------------
Mvan_1155|M.vanbaalenii_PYR-1       -------------------WVDDDHVATANE-------------------
MSMEG_1313|M.smegmatis_MC2_155      -------------------WIDDTHVATANE-------------------
TH_1547|M.thermoresistible__bu      -------------------WIGDDHLATANE-------------------
Rv2048c|M.tuberculosis_H37Rv        VGEAQFVELPTYAFQRRRFWLSGDGVAADAAGLGLAASEHALLGAVIDLP
                                                       *:..  :*:                      

Mflv_5160|M.gilvum_PYR-GCK          --------GDWKGGTRGWSIFDAGTGEVVWDAGNSVEQLAVRTGLHIESR
Mvan_1155|M.vanbaalenii_PYR-1       --------GDWKGGTRGWTIFDATTGEVVWDAGNTVEQLAVRTGMHIEGR
MSMEG_1313|M.smegmatis_MC2_155      --------GDWKGGTRGWTIFDATTGDVVWDAGNTFEQLAVRTGLHIESR
TH_1547|M.thermoresistible__bu      --------GDWKGGTRGWSIFDANSGELVWDAGNSFAQLAVRAGLHIESR
Rv2048c|M.tuberculosis_H37Rv        ASGGVVLTGRLSPSVQGWLADHSVAGVTIFPG-AGFVELAIRAGDEVGCG
                                            *  . ..:**   .: :*  :: .   . :**:*:* .:   

Mflv_5160|M.gilvum_PYR-GCK          AESKGPEPEGLAITEIGGRPVALVASERSN----FVAVYDVSDATN----
Mvan_1155|M.vanbaalenii_PYR-1       SESKGPEPEGLAITEIGGRPTALVASERSN----FVAVYDVSDVTA----
MSMEG_1313|M.smegmatis_MC2_155      AESKGPEPEGLAITDLDGRRTALIASERSN----FVAVYDVTDPSS----
TH_1547|M.thermoresistible__bu      AEAKGPEPEGLTVTELAGRPTVLVASERSN----FVAVYDVTDVTA----
Rv2048c|M.tuberculosis_H37Rv        VVDESTLAAPLVLPASGSVAVQVVVNGPDESGVRGVSVYSRGDVGTGWVL
                                       :.. .  *.:.   .  . ::..  .:     *:**.  *       

Mflv_5160|M.gilvum_PYR-GCK          ---------------------------------------------PQFR-
Mvan_1155|M.vanbaalenii_PYR-1       ---------------------------------------------PQFR-
MSMEG_1313|M.smegmatis_MC2_155      ---------------------------------------------PVFR-
TH_1547|M.thermoresistible__bu      ---------------------------------------------PQFR-
Rv2048c|M.tuberculosis_H37Rv        HAEGALRAGSAEPTADLAMWPPAGAVPVEVADGYQQLAERGYGYGPAFRG
                                                                                 * ** 

Mflv_5160|M.gilvum_PYR-GCK          --------------QMLPATP-------GPEGILPVPARDLLVISSESDD
Mvan_1155|M.vanbaalenii_PYR-1       --------------QILPTTP-------GPEGVLPIPSRELVVISSEADD
MSMEG_1313|M.smegmatis_MC2_155      --------------QILPTTP-------GPEGILPIPSRNLLAISSETDD
TH_1547|M.thermoresistible__bu      --------------QLLPTTP-------GPEGVLAIPARDLLVISSETDD
Rv2048c|M.tuberculosis_H37Rv        LTAMWRRGDEVFAEVALPADAGVSVTGFGVHPVLLDAALHAVVLSAESAE
                                                    **: .       * . :*  .: . :.:*:*: :

Mflv_5160|M.gilvum_PYR-GCK          AEAR------VRATVTVYGFGERYA--GAPP-FPSIVSGDVDG-TPIAWG
Mvan_1155|M.vanbaalenii_PYR-1       AEAR------VRASVTVYGFGAEFA--GAKPSFPSIVSGDVDD-APIAWG
MSMEG_1313|M.smegmatis_MC2_155      AENR------VRASVSVYGFGEQYAKVGGTPSFPSIVSGDIDN-VPIGWG
TH_1547|M.thermoresistible__bu      ADAR------VRASISVYGYGGQHAAAGGTPPFPSIVSGDLAD-VPIGWG
Rv2048c|M.tuberculosis_H37Rv        RGQGSVLVPFSWQGVSLHAAGASAVRARIAPVGPSAVSIELADGLGLPVL
                                                  ::::. *   .     *  ** ** :: .   :   

Mflv_5160|M.gilvum_PYR-GCK          ALGALSADPADENRLYTAPDVAYGPSRILGVDLTQTPALIDTELPVTEAG
Mvan_1155|M.vanbaalenii_PYR-1       ALSALSADPADENRLYTSTDNAYGPSRILGIDLTKTPALIDTQLPITDNG
MSMEG_1313|M.smegmatis_MC2_155      ALGALSADPKNPDRLYTATDNAYGPARILGIDTAQTPALIDTELAVTEDG
TH_1547|M.thermoresistible__bu      ALGALSADPADENRLYTATDIAYGPARLLGVDVSRSPAVIDSELVVTADG
Rv2048c|M.tuberculosis_H37Rv        SVASMLARPVTDQQLRAAVSSS-GPDRLFEVTWSPQPSAAVEPLPVCAWG
                                    ::.:: * *   ::* :: . : ** *:: :  :  *:     * :   *

Mflv_5160|M.gilvum_PYR-GCK          EAVTLDVEGVAARPDGGFVLAVEG---EEGPGNQLVFVGADGA------I
Mvan_1155|M.vanbaalenii_PYR-1       QPVTLDVEGVAAKPDGGFVLAVEG---EEGPGNELVFVAADGK------I
MSMEG_1313|M.smegmatis_MC2_155      KPVTLDTEGLAARPDGGFVLAVEG---EEGPENELVFVDAEGG------I
TH_1547|M.thermoresistible__bu      DPVTLDVEGVAARPDGGFVLAVEGDPDEPGLDNEVVFVGADGG------I
Rv2048c|M.tuberculosis_H37Rv        TTEDSAAVVFESVPLAGDVVAGVYAATSSVLDVLQSWLTRDGAGVLVVMT
                                     .    .  . : * .* *:*      .        ::  :*        

Mflv_5160|M.gilvum_PYR-GCK          ERRVSLPSEVAAGLGGQGFEGVALDGDAVWVAVQREVKTDP---------
Mvan_1155|M.vanbaalenii_PYR-1       EKRVSLPADVAAGLGGQGLEGVAVDGDAVWVALQREVKTDP---------
MSMEG_1313|M.smegmatis_MC2_155      DKHVKLPADIAAQLGGQGLEGVAVDGDAVWVALQRELKSDP---------
TH_1547|M.thermoresistible__bu      ERRVALPDDIAAGLGGQGLEGVALDGDDVWVAVQRELTGDP---------
Rv2048c|M.tuberculosis_H37Rv        RGAVALPGEDVTDLAGAAVWGLVRSAQTEHPGRIVLVDSDAPLDDSALAA
                                       * ** : .: *.* .. *:. ..:    .    :  *.         

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        VVTTGEPQVLWRRGEVYTARVHGSRAVGGLLVPPSDRPWRLAMSTAGTFE
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          ---------------SGVARLGRYLPDS---DTWEWFGYPLESTDVDGDW
Mvan_1155|M.vanbaalenii_PYR-1       ---------------KGVARIGRYTPAD---DRWEWFGYQLDSTDTEGDW
MSMEG_1313|M.smegmatis_MC2_155      ---------------TGVVRIGRYTPEG---DRWEWYGYPLEATSVDGDW
TH_1547|M.thermoresistible__bu      ---------------PGVVRIGRYRAGGGGQDVWEWFGYPLERTDAEGDW
Rv2048c|M.tuberculosis_H37Rv        NLRLELIPDADAPLGPGQVRVAVSAIAANFRDVMIALGLYPDPDAVMGVE
                                                    * .*:.         *     *   :   . *  

Mflv_5160|M.gilvum_PYR-GCK          IG--LSEIQVHDGALLVLERDK---LNGPDARVKAIYRVALPTGAGATGA
Mvan_1155|M.vanbaalenii_PYR-1       IG--LSEIQVHDGSLLVLERDK---LNGPDARVKAIYRVAIPDGGGATGA
MSMEG_1313|M.smegmatis_MC2_155      IG--LSELTVHDGQLLVLERDK---LNGPDAHVKSLYRVAIPDGEGVTSA
TH_1547|M.thermoresistible__bu      IG--LSEIAVHDGNLLVLERDK---LNGPDARMKAVYRVAIPAGPGVRTA
Rv2048c|M.tuberculosis_H37Rv        ACGVVIETSLNKGSFAVGDRVMGLFPEGTGTVASTDQRLLVKVPAGWSHT
                                        : *  ::.* : * :*      :*..:  .:  *: :    *   :

Mflv_5160|M.gilvum_PYR-GCK          -AAPPLLPKALARDLLPDLQATRGYTQEKVEG------------------
Mvan_1155|M.vanbaalenii_PYR-1       -EAPKVLPKTLARNILPDLQANRGFTQEKVEG------------------
MSMEG_1313|M.smegmatis_MC2_155      GEAPRVLQKTLARNLLPDLQATHGYVQEKVEG------------------
TH_1547|M.thermoresistible__bu      AEAPPVLAKTPARDLLPDLRATNGFTQEKVEG------------------
Rv2048c|M.tuberculosis_H37Rv        AAATTSVVFATAHYALVDLAAARSGQRVLIHAGTGGVGMAAVQLARHLGL
                                      *.  :  : *:  * ** * ..  :  :..                  

Mflv_5160|M.gilvum_PYR-GCK          --FAIAGNGSLYVVTDNDGLDDANGETVFLDLGPAGDALR----------
Mvan_1155|M.vanbaalenii_PYR-1       --FAVAGNGKLYVVTDNDGLDDANGETVFLDLGSAGQALGG---------
MSMEG_1313|M.smegmatis_MC2_155      --VTVGGNGNLYAITDNDGLDDTNGETVFLDLGPAAEALDG---------
TH_1547|M.thermoresistible__bu      --LTVAGNGRLYVVTDNDGLDDANGETVFLDLGPATAALGG---------
Rv2048c|M.tuberculosis_H37Rv        EVFATASKGKWDTLRAMGFDDDHISDSRSLEFEDKFRAATGGRGFDVVLD
                                      .: ..:*   .:   .  **  .::  *::     *            

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        SLAGEFVDASLRLVAPGGVFLEMGKTDIRDPGVIAQQYPGVRYRAFDLFE
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        PGPDRIAQILAELATLFGDGVLRPLPVTTFDVRCAPAALRYLSQARHTGK
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        VVMLMPGSWAAGTVLITGGTGMAGSAVARHVVARHGVRNLVLVSRRGPDA
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        PGAAELVAELAAAGAQVQVVACDAADRAALAKVIADIPVQHPLSGVIHTA
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        GALDDAVVMSLTPDRVDVVLRSKVDAAWHLHELTRDLDVSAFVMFSSMAG
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        LVGSSGQANYAAANSFLDALAAHRRAHGLPAISLGWGLWDQASAMTGGLA
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        TVDFKRFARDGIVAMSSADALQLFDTAMIVDEPFMLPAHIDFAALKVKFD
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        GGTLPPMFVDLINAPTRRQVDDSLAAAKSKSALLQRLEGLPEDEQHAVLL
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        DLVRSHIATVLGSASPEAIDPDRAFQELGFDSLTAVEMRNRLKSATGLAL
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        SPTLIFDYPNSAALAGYMRRELLGSSPQDTSAVAAGEAELQRIVASIPVK
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1155|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1313|M.smegmatis_MC2_155      --------------------------------------------------
TH_1547|M.thermoresistible__bu      --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        RLRQAGVLDLLLALANETETSGQDPALAPTAEQEIADMDLDDLVNAAFRN
                                                                                      

Mflv_5160|M.gilvum_PYR-GCK          ---
Mvan_1155|M.vanbaalenii_PYR-1       ---
MSMEG_1313|M.smegmatis_MC2_155      ---
TH_1547|M.thermoresistible__bu      ---
Rv2048c|M.tuberculosis_H37Rv        DDE