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MTASHLARAMTTAAIAALLLAACSTDTQDEAPAESTDTPKATSPIDFNLPDAERFHRAATYPVYLNRPAG EDPAAETVAEISTVTPDGNTLIYTDAAAKRIGFLDIRDAAKPVGLGTLSLEELGHADDQPTSVAAVGEFV LVVVDTTGGDFTKPSGRVDVVRVADRTRVHSIDLGGQPDSIAIAGDGSFAAIAMENQRDEEFTPPGAEEG DLPQPPTGFLQLISLTGAPTGWTPRKVEFDVEAARAAGLDTPEDLEPEYVSINSRGQVAVTMQENNGIAI VDGRTGAVQKIFSAGTASVSGIDTAEDDTVDQTGSITDTPREPDSIGWVDDDHVATANEGDWKGGTRGWT IFDATTGEVVWDAGNTVEQLAVRTGMHIEGRSESKGPEPEGLAITEIGGRPTALVASERSNFVAVYDVSD VTAPQFRQILPTTPGPEGVLPIPSRELVVISSEADDAEARVRASVTVYGFGAEFAGAKPSFPSIVSGDVD DAPIAWGALSALSADPADENRLYTSTDNAYGPSRILGIDLTKTPALIDTQLPITDNGQPVTLDVEGVAAK PDGGFVLAVEGEEGPGNELVFVAADGKIEKRVSLPADVAAGLGGQGLEGVAVDGDAVWVALQREVKTDPK GVARIGRYTPADDRWEWFGYQLDSTDTEGDWIGLSEIQVHDGSLLVLERDKLNGPDARVKAIYRVAIPDG GGATGAEAPKVLPKTLARNILPDLQANRGFTQEKVEGFAVAGNGKLYVVTDNDGLDDANGETVFLDLGSA GQALGG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1155 | - | - | 100% (776) | secreted protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_5160 | - | 0.0 | 81.33% (766) | secreted protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1313 | - | 0.0 | 77.36% (773) | secreted protein |
| M. thermoresistible (build 8) | TH_1547 | - | 0.0 | 65.53% (789) | secreted protein |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1155|M.vanbaalenii_PYR-1 ---MTASHLARAMTTAAIAALLLAACSTDTQDEAPA-ESTDTPKATSPID
Mflv_5160|M.gilvum_PYR-GCK MAVHWTPNWTCATATGLTATLLLAGCSRGPDDEGAT-PIRER--ATAAVD
MSMEG_1313|M.smegmatis_MC2_155 -MTWMSQPTARAAALTTLVALIAAGCATE-KEPSRD-DASPGPRAISPID
TH_1547|M.thermoresistible__bu --VQIFRLSRTGLAVAGAVTMALTACSTADDHPRPDGDGADRVRATSTIE
. : .:: :.*: .. * :.::
Mvan_1155|M.vanbaalenii_PYR-1 FNLPDAERFHRAATYPVYLNRPAGEDPAAETVAEISTVTPDGNTLIYTDA
Mflv_5160|M.gilvum_PYR-GCK FTLPDAQRYHRLATYPVHLNKPATDPVDAETVAEISTVTPDGNTVIYTDA
MSMEG_1313|M.smegmatis_MC2_155 WNLPAAERYHRTATYPVFLNRPADDPVDAETVAEISTVTPDGNTLIYTDA
TH_1547|M.thermoresistible__bu WVPPPDQRYHRLATFPVYLNRPDGEAADTETVAEISTVTPDGGTVVYTDA
: * :*:** **:**.**:* : :*************.*::****
Mvan_1155|M.vanbaalenii_PYR-1 AAKRIGFLDIRDAAKPVGLGTLSLEELGHADDQPTSVAAVGEFVLVVVDT
Mflv_5160|M.gilvum_PYR-GCK AGKRIGFLDIRDPANPVGLGTLSLAELGHADDQPTSVAAVGEYVLVVVDT
MSMEG_1313|M.smegmatis_MC2_155 AAKRIGFVDITDPANPAGKGTLSLKELGHQDDQPTSVAAVGEFVLVVVDT
TH_1547|M.thermoresistible__bu AAKRIGFLDIRDPAAPVGVGTLSLTDLGPPTDSGPSTGPG----------
*.*****:** *.* *.* ***** :** *. .*...
Mvan_1155|M.vanbaalenii_PYR-1 TGGDFTKPSGRVDVVRVADRTRVHSIDLGGQPDSIAIAGDGSFAAIAMEN
Mflv_5160|M.gilvum_PYR-GCK TGGDFANPSGRVDVVRVADRTRVHSVDLGGQPDSIAVAHDGSFAAIAIEN
MSMEG_1313|M.smegmatis_MC2_155 TGGDFPHPSGRVDIVRVADRTRVHSIDLGGQPDSIAISPDGTFAAIAMEN
TH_1547|M.thermoresistible__bu SADDQPTSVAAVDEY------------------VLVVGPDGTLAAVAIEN
:..* . . . ** :.:. **::**:*:**
Mvan_1155|M.vanbaalenii_PYR-1 QRDEEFTPPGAEEGDLPQPPTGFLQLISLTGAPTGWTPRKVEFDVEAARA
Mflv_5160|M.gilvum_PYR-GCK QRDEEFTPPGAEEGDLPQPPTGFVQLLDLAGAPDTWVPRRVDFDVDAARA
MSMEG_1313|M.smegmatis_MC2_155 QRDEEFTPPGGEEGDLPQPPTGFVQLIDLTGAPDTWTPRRSDFDVEAARA
TH_1547|M.thermoresistible__bu QRDEEFTPPGGQEGDLPQPPTGFVALIDLTGEPADWR-------------
**********.:***********: *:.*:* * *
Mvan_1155|M.vanbaalenii_PYR-1 AGLDTPEDLEPEYVSINSRGQVAVTMQENNGIAIVDGRTGAVQKIFSAGT
Mflv_5160|M.gilvum_PYR-GCK AGLDTPEDLEPEYVSVNARGQVAVTLQENNGIAIIDGRTGAVQKISSAGT
MSMEG_1313|M.smegmatis_MC2_155 AGLDTPEDLEPEYVSINSRGQVAVTLQENNGIAIIDGATGDVAKIFSAGS
TH_1547|M.thermoresistible__bu GGGGAPEDLEPEYVDINSRGQVAVSLQENNGFAVIDGVTGEVTGIFSAGT
.* .:*********.:*:******::*****:*::** ** * * ***:
Mvan_1155|M.vanbaalenii_PYR-1 ASVSGIDTAEDDTVDQTGSITDTPREPDSIGWVDDDHVATANEGDWKGGT
Mflv_5160|M.gilvum_PYR-GCK ESVTGIDTAEDGGVEQTGSITDTPREPDAIGWIDDTHVATANEGDWKGGT
MSMEG_1313|M.smegmatis_MC2_155 ESVEGIDTVEDDTIDQTGSILETPREPDAIGWIDDTHVATANEGDWKGGT
TH_1547|M.thermoresistible__bu QSVAGIDTTEDGVIDQSGSIGDTPREPDAIGWIGDDHLATANEGDWKGGT
** ****.**. ::*:*** :******:***:.* *:************
Mvan_1155|M.vanbaalenii_PYR-1 RGWTIFDATTGEVVWDAGNTVEQLAVRTGMHIEGRSESKGPEPEGLAITE
Mflv_5160|M.gilvum_PYR-GCK RGWSIFDAGTGEVVWDAGNSVEQLAVRTGLHIESRAESKGPEPEGLAITE
MSMEG_1313|M.smegmatis_MC2_155 RGWTIFDATTGDVVWDAGNTFEQLAVRTGLHIESRAESKGPEPEGLAITD
TH_1547|M.thermoresistible__bu RGWSIFDANSGELVWDAGNSFAQLAVRAGLHIESRAEAKGPEPEGLTVTE
***:**** :*::******:. *****:*:***.*:*:********::*:
Mvan_1155|M.vanbaalenii_PYR-1 IGGRPTALVASERSNFVAVYDVSDVTAPQFRQILPTTPGPEGVLPIPSRE
Mflv_5160|M.gilvum_PYR-GCK IGGRPVALVASERSNFVAVYDVSDATNPQFRQMLPATPGPEGILPVPARD
MSMEG_1313|M.smegmatis_MC2_155 LDGRRTALIASERSNFVAVYDVTDPSSPVFRQILPTTPGPEGILPIPSRN
TH_1547|M.thermoresistible__bu LAGRPTVLVASERSNFVAVYDVTDVTAPQFRQLLPTTPGPEGVLAIPARD
: ** ..*:*************:* : * ***:**:******:*.:*:*:
Mvan_1155|M.vanbaalenii_PYR-1 LVVISSEADDAEARVRASVTVYGFGAEFA--GAKPSFPSIVSGDVDDAPI
Mflv_5160|M.gilvum_PYR-GCK LLVISSESDDAEARVRATVTVYGFGERYA--GAPP-FPSIVSGDVDGTPI
MSMEG_1313|M.smegmatis_MC2_155 LLAISSETDDAENRVRASVSVYGFGEQYAKVGGTPSFPSIVSGDIDNVPI
TH_1547|M.thermoresistible__bu LLVISSETDDADARVRASISVYGYGGQHAAAGGTPPFPSIVSGDLADVPI
*:.****:***: ****:::***:* ..* *. * ********: ..**
Mvan_1155|M.vanbaalenii_PYR-1 AWGALSALSADPADENRLYTSTDNAYGPSRILGIDLTKTPALIDTQLPIT
Mflv_5160|M.gilvum_PYR-GCK AWGALGALSADPADENRLYTAPDVAYGPSRILGVDLTQTPALIDTELPVT
MSMEG_1313|M.smegmatis_MC2_155 GWGALGALSADPKNPDRLYTATDNAYGPARILGIDTAQTPALIDTELAVT
TH_1547|M.thermoresistible__bu GWGALGALSADPADENRLYTATDIAYGPARLLGVDVSRSPAVIDSELVVT
.****.****** : :****:.* ****:*:**:* :::**:**::* :*
Mvan_1155|M.vanbaalenii_PYR-1 DNGQPVTLDVEGVAAKPDGGFVLAVEG---EEGPGNELVFVAADGKIEKR
Mflv_5160|M.gilvum_PYR-GCK EAGEAVTLDVEGVAARPDGGFVLAVEG---EEGPGNQLVFVGADGAIERR
MSMEG_1313|M.smegmatis_MC2_155 EDGKPVTLDTEGLAARPDGGFVLAVEG---EEGPENELVFVDAEGGIDKH
TH_1547|M.thermoresistible__bu ADGDPVTLDVEGVAARPDGGFVLAVEGDPDEPGLDNEVVFVGADGGIERR
*..****.**:**:*********** * * *::*** *:* *:::
Mvan_1155|M.vanbaalenii_PYR-1 VSLPADVAAGLGGQGLEGVAVDGDAVWVALQREVKTDPKGVARIGRYTPA
Mflv_5160|M.gilvum_PYR-GCK VSLPSEVAAGLGGQGFEGVALDGDAVWVAVQREVKTDPSGVARLGRYLPD
MSMEG_1313|M.smegmatis_MC2_155 VKLPADIAAQLGGQGLEGVAVDGDAVWVALQRELKSDPTGVVRIGRYTPE
TH_1547|M.thermoresistible__bu VALPDDIAAGLGGQGLEGVALDGDDVWVAVQRELTGDPPGVVRIGRYRAG
* ** ::** *****:****:*** ****:***:. ** **.*:*** .
Mvan_1155|M.vanbaalenii_PYR-1 D---DRWEWFGYQLDSTDTEGDWIGLSEIQVHDGSLLVLERDKLNGPDAR
Mflv_5160|M.gilvum_PYR-GCK S---DTWEWFGYPLESTDVDGDWIGLSEIQVHDGALLVLERDKLNGPDAR
MSMEG_1313|M.smegmatis_MC2_155 G---DRWEWYGYPLEATSVDGDWIGLSELTVHDGQLLVLERDKLNGPDAH
TH_1547|M.thermoresistible__bu GGGQDVWEWFGYPLERTDAEGDWIGLSEIAVHDGNLLVLERDKLNGPDAR
. * ***:** *: *..:********: **** **************:
Mvan_1155|M.vanbaalenii_PYR-1 VKAIYRVAIPDGGGATGA-EAPKVLPKTLARNILPDLQANRGFTQEKVEG
Mflv_5160|M.gilvum_PYR-GCK VKAIYRVALPTGAGATGA-AAPPLLPKALARDLLPDLQATRGYTQEKVEG
MSMEG_1313|M.smegmatis_MC2_155 VKSLYRVAIPDGEGVTSAGEAPRVLQKTLARNLLPDLQATHGYVQEKVEG
TH_1547|M.thermoresistible__bu MKAVYRVAIPAGPGVRTAAEAPPVLAKTPARDLLPDLRATNGFTQEKVEG
:*::****:* * *. * ** :* *: **::****:*..*:.******
Mvan_1155|M.vanbaalenii_PYR-1 FAVAGNGKLYVVTDNDGLDDANGETVFLDLGSAGQALGG
Mflv_5160|M.gilvum_PYR-GCK FAIAGNGSLYVVTDNDGLDDANGETVFLDLGPAGDALR-
MSMEG_1313|M.smegmatis_MC2_155 VTVGGNGNLYAITDNDGLDDTNGETVFLDLGPAAEALDG
TH_1547|M.thermoresistible__bu LTVAGNGRLYVVTDNDGLDDANGETVFLDLGPATAALGG
.::.*** **.:********:**********.* **