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M. thermoresistible (build 8) TH_1477 (-)

annotation: Probable UPD-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol-N-acetylglucosamine transferase MurG
coordinates: 2789346 - 2790557
length: 404

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1477--100% (404)Probable UPD-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol-N-acetylglucosamine transferase MurG

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2177cmurG1e-15177.05% (366) undecaprenyldiphospho-muramoylpentapeptide beta-N-
M. gilvum PYR-GCKMflv_2988murG1e-16481.02% (374) N-acetylglucosaminyl transferase
M. tuberculosis H37RvRv2153cmurG1e-15177.05% (366) undecaprenyldiphospho-muramoylpentapeptide beta-N-
M. leprae Br4923MLBr_00914murG1e-15375.53% (380) undecaprenyldiphospho-muramoylpentapeptide beta-N-
M. abscessus ATCC 19977MAB_2006murG1e-15675.13% (378) undecaprenyldiphospho-muramoylpentapeptide beta-N-
M. marinum MMMAR_3193murG1e-15677.69% (381) UDP-N-acetylglucosamine-N-acetylmuramyl- (pentapeptide)
M. avium 104MAV_2336murG1e-16078.46% (376) N-acetylglucosaminyl transferase
M. smegmatis MC2 155MSMEG_4227murG1e-16480.32% (376) N-acetylglucosaminyl transferase
M. ulcerans Agy99MUL_3501murG1e-15677.43% (381) undecaprenyldiphospho-muramoylpentapeptide beta-N-
M. vanbaalenii PYR-1Mvan_3523murG1e-16278.48% (381) N-acetylglucosaminyl transferase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_3193|M.marinum_M               MNDTVREPTGGLGV-NHGPA---------------LSVVLAGGGTAGHVE
MUL_3501|M.ulcerans_Agy99           MNDTVREPAGGLGV-NHGPA---------------LSVVLAGGGTAGHVE
MAV_2336|M.avium_104                MNDTVKKPTGGRGD-DPLPAGAALSAVAPH---EPVSVVLAGGGTAGHVE
Mb2177c|M.bovis_AF2122/97           MKDTVSQPAGGRGATAPRPADAASPSCGSSPSADSLSVVLAGGGTAGHVE
Rv2153c|M.tuberculosis_H37Rv        MKDTVSQPAGGRGATAPRPADAASPSCGSSPSADSVSVVLAGGGTAGHVE
MLBr_00914|M.leprae_Br4923          MNNSVREPTRGRRG-SPPVADAALSVN------PPLSVVLAGGGTAGHVE
MAB_2006|M.abscessus_ATCC_1997      MSDELRP----------------------------LSVVLAGGGTAGHVE
TH_1477|M.thermoresistible__bu      MPD----------------PEDREMVD------REISVVLAGGGTAGHVE
MSMEG_4227|M.smegmatis_MC2_155      MNKG---------------SRDNNHSD------RGISVVLAGGGTAGHVE
Mflv_2988|M.gilvum_PYR-GCK          MT-------------GISVPAGQARRD------RAISVVLAGGGTAGHIE
Mvan_3523|M.vanbaalenii_PYR-1       MTRISVPAGQERNDGGISVPAGQERSD------RGISVVLAGGGTAGHIE
                                    *                                  :************:*

MMAR_3193|M.marinum_M               PAMAVADALSVLEPNVRITALGTARGLETRLVPARGYHLELITPVPLPRK
MUL_3501|M.ulcerans_Agy99           PAMAVADALSVLEPNVRITALGTSRGLETRLVPARGYHLELITPVPLPRK
MAV_2336|M.avium_104                PAMAVADALKALDPNVRITSLGTARGLETRLVPERGYDLELITPVPLPRK
Mb2177c|M.bovis_AF2122/97           PAMAVADALVALDPRVRITALGTPRGLETRLVPQRGYHLELITAVPMPRK
Rv2153c|M.tuberculosis_H37Rv        PAMAVADALVALDPRVRITALGTLRGLETRLVPQRGYHLELITAVPMPRK
MLBr_00914|M.leprae_Br4923          PAMAVADALRALDPQVRITALGTSRGLETRLVPERGYHLELITPVPLPRK
MAB_2006|M.abscessus_ATCC_1997      PAMAVADALREIDPTVRITALGTERGLETRLVPDRGYHLELIVPVPLPRR
TH_1477|M.thermoresistible__bu      PAMAVADALTALEPGVRITALGTHRGLETRLVPERGYRLELITPVPLPRK
MSMEG_4227|M.smegmatis_MC2_155      PAMAVADALRALDPDVRITALGTQRGLETRLVPQRGYDLELITPVPLPRK
Mflv_2988|M.gilvum_PYR-GCK          PAMAVADALTALEPNVRITALGTARGLETRLVPQRGYDLELITPVPLPRK
Mvan_3523|M.vanbaalenii_PYR-1       PAMAVADALTALDPDVRITALGTERGLETRLVPQRGYHLELITLVPLPRK
                                    *********  ::* ****:*** ********* *** ****. **:**:

MMAR_3193|M.marinum_M               PSGDLARLPPRVWRAVRETRAVLDLVDADVVIGFGGYVALPAYLAARGIP
MUL_3501|M.ulcerans_Agy99           PSGDLARLPPRVWRSVRETRAVLDLVDADVVIGFGGYVALPAYLAARGIP
MAV_2336|M.avium_104                PTGDLARLPSRVWRAVRETRAVLHAVDADVVIGFGGYVALPAYLAARGVS
Mb2177c|M.bovis_AF2122/97           PGGDLARLPSRVWRAVREARDVLDDVDADVVVGFGGYVALPAYLAARGLP
Rv2153c|M.tuberculosis_H37Rv        PGGDLARLPSRVWRAVREARDVLDDVDADVVVGFGGYVALPAYLAARGLP
MLBr_00914|M.leprae_Br4923          LTGDLARLPLRVWRAVRETRAVFEVVEAHVVVGFGGYVALPAYLAARGIP
MAB_2006|M.abscessus_ATCC_1997      LTGDLVRLPLRVRRAVRQTRAVFDGVQADVVIGFGGYVALPAYLAARRGP
TH_1477|M.thermoresistible__bu      PTADLARLPLRVRRAVRETRAVLDAVRADVVIGFGGYVALPAYLAARGGL
MSMEG_4227|M.smegmatis_MC2_155      PSKDLLRLPMRVRTAIRQTRDVLTGVNADVVVGFGGYVALPAYLAARGGL
Mflv_2988|M.gilvum_PYR-GCK          LSADLLRLPMRVRRAVRETRAVFEAVDADVVIGFGGYVALPAYLAAR---
Mvan_3523|M.vanbaalenii_PYR-1       LSADLFRLPMRVLRAVRQTRRILDEVSADVVVGFGGYVAVPAYLAARS-L
                                       ** *** **  ::*::* ::  * *.**:*******:*******   

MMAR_3193|M.marinum_M               G---LRRRIPVVIHEANARAGLANRVGLRTADRVLSAVPDSGLRGAEVVG
MUL_3501|M.ulcerans_Agy99           G---LRRRIPVVIHEANARAGLANRVGLRTADRVLSAVPDSGLRGAEVVG
MAV_2336|M.avium_104                P---RKPRVPVVIHEANASAGLANRVGARTAQRVLSAVADCGLPGAEVVG
Mb2177c|M.bovis_AF2122/97           LPPRRRRRIPVVIHEANARAGLANRVGAHTADRVLSAVPDSGLRRAEVVG
Rv2153c|M.tuberculosis_H37Rv        LPPRRRRRIPVVIHEANARAGLANRVGAHTADRVLSAVPDSGLRRAEVVG
MLBr_00914|M.leprae_Br4923          R---VRRRIPVVVHEANARAGIANRVGVRTAERVLSAVPGSGLRGAEVVG
MAB_2006|M.abscessus_ATCC_1997      L---RRRRVPVVIHEANARAGLANRVGARGAQRVLSAVPDSGLRDAEVVG
TH_1477|M.thermoresistible__bu      R---RRSAVPVVVHEANAHAGWANRVGARAAQRVLSAVPDPGLGPVEVVG
MSMEG_4227|M.smegmatis_MC2_155      T---GRRKVPVVVHEANARAGLANRVGARSARRVLSAVPDSGLRNVEVVG
Mflv_2988|M.gilvum_PYR-GCK          ------RRVPVVVHEANASAGWANKVGARVATRVLSAVPDPGLGHVDVVG
Mvan_3523|M.vanbaalenii_PYR-1       R---THRRVPVVVHEANASAGWANKVGARSAQRVLSAVPDPGLPHVEVVG
                                            :***:***** ** **:** : * ******.. **  .:***

MMAR_3193|M.marinum_M               VPVRAAITALDRMALRAEARAHFGFADDARVLLVFGGSQGAVSLNKAVSA
MUL_3501|M.ulcerans_Agy99           VPVRAAITALDRMALRAEARAHFGFADDARVLLVFGGSQGAVSLNKAVSA
MAV_2336|M.avium_104                VPVREAITSLDRAAVRAEARRHFGFADDARVLLVFGGSQGAASLNRAVSG
Mb2177c|M.bovis_AF2122/97           VPVRASIAALDRAVLRAEARAHFGFPDDARVLLVFGGSQGAVSLNRAVSG
Rv2153c|M.tuberculosis_H37Rv        VPVRASIAALDRAVLRAEARAHFGFPDDARVLLVFGGSQGAVSLNRAVSG
MLBr_00914|M.leprae_Br4923          VPIHATITTLNRPALRADARKHFGFTDDARVLLVFGGSQGAVSLNRAVAG
MAB_2006|M.abscessus_ATCC_1997      VPVRGSITALDRAALRHQARAHYGFDDDALVLLVFGGSQGAVSLNNAVSA
TH_1477|M.thermoresistible__bu      VPLRSSITSMDRHALRAEARACFGFDADARVLLVFGGSQGAQSINRAVAA
MSMEG_4227|M.smegmatis_MC2_155      VPVRESITSLDRAALRAQARAEFGFAEDARVLLVFGGSQGAQSINRAVSA
Mflv_2988|M.gilvum_PYR-GCK          VPVREAITSLDRSALRAEARAHFGFADDARVLLVFGGSQGAQSLNRAVSG
Mvan_3523|M.vanbaalenii_PYR-1       VPVREAITSLDRMALRAEARAHFGFADDARVLLVFGGSQGAQSLNRAVAG
                                    **:: :*::::* .:* :**  :**  ** *********** *:*.**:.

MMAR_3193|M.marinum_M               AAAELAASGVSVLHAHGPKNVLELLAPRTPGQDDPPYVAVPYLDRMDLAY
MUL_3501|M.ulcerans_Agy99           AAAELAASGVSVLHAHGPKNVLELLAPRTPDQDDPPYVAVPYLDRMDLAY
MAV_2336|M.avium_104                AAAQLAAAGVSVLHAHGPKNTLDLREPQP---GDPPYVAVPYLDRMDLAY
Mb2177c|M.bovis_AF2122/97           AAADLAAAGVCVLHAHGPQNVLELRRRAQ---GDPPYVAVPYLDRMELAY
Rv2153c|M.tuberculosis_H37Rv        AAADLAAAGVCVLHAHGPQNVLELRRRAQ---GDPPYVAVPYLDRMELAY
MLBr_00914|M.leprae_Br4923          AAEDLAASGVAVLHAYGLKNTLELRTPEY---GEPPYVAVPYLDRMDLAY
MAB_2006|M.abscessus_ATCC_1997      AANDLAAAGVSVLHAHGPKNTIKLPERPP---GAPRYVALPYLDRMDLAY
TH_1477|M.thermoresistible__bu      AARRLAAAGISVLHAHGPKNTLQLPAPAD---GAPPYVAVPYLDRMDLAY
MSMEG_4227|M.smegmatis_MC2_155      AAKDLAAAGISVLHAHGPKNTLDLPPADP---QAPPYVAVPYLDRMDLAY
Mflv_2988|M.gilvum_PYR-GCK          AAEGLAAAGISVLHAHGPKNTLDLRAPRP---GDPPYVAVPYLERMDLAY
Mvan_3523|M.vanbaalenii_PYR-1       AAEKLAEQGISVLHAHGPKNTLDLPAPRP---GDPPYVAVPYLERMDLAY
                                    **  **  *:.****:* :*.:.*          * ***:***:**:***

MMAR_3193|M.marinum_M               AAADLVICRSGAMTVAEVSAVGLPAIYVPLPIGNGEQRLNALPVVNAGGG
MUL_3501|M.ulcerans_Agy99           AAADLVICRSGAMTVAEVSAVGLPAIYVPLPIGNGEQRLNALPVVNAGGG
MAV_2336|M.avium_104                AAADLVICRSGAMTVAEVSAVGLPAIYVPLPIGNGEQRLNALPVVNAGGG
Mb2177c|M.bovis_AF2122/97           AAADLVICRAGAMTVAEVSAVGLPAIYVPLPIGNGEQRLNALPVVNAGGG
Rv2153c|M.tuberculosis_H37Rv        AAADLVICRAGAMTVAEVSAVGLPAIYVPLPIGNGEQRLNALPVVNAGGG
MLBr_00914|M.leprae_Br4923          AAADLVICRSGAMTVAEVSAVGLPAIYVPFPIGNGEQRLNALPVVNAGGG
MAB_2006|M.abscessus_ATCC_1997      AAADIAVCRSGAMTVAEVSAVGLPAIYVPLPIGNGEQRLNALPIVDAGGG
TH_1477|M.thermoresistible__bu      AAADLAICRSGAMTVAEVSAVGLPAIYVPLPIGNGEQRFNALPVVQAGGG
MSMEG_4227|M.smegmatis_MC2_155      AAADLAICRSGAMTVAEVTAVGLPAIYVPLPIGNGEQRLNALPVVDAGGG
Mflv_2988|M.gilvum_PYR-GCK          AAADLAVCRSGAMTVAEVSAVGLPAVYVPLPIGNGEQRLNALPVVEAGGG
Mvan_3523|M.vanbaalenii_PYR-1       AAADLAVCRSGAMTVAEVSAVGLPAVYVPLPIGNGEQRLNALPVVEAGGG
                                    ****:.:**:********:******:***:********:****:*:****

MMAR_3193|M.marinum_M               MVVADADLTPALVAREVTGLLTDPPRLAAMTAAAAQVGHRDAAAQVAQAA
MUL_3501|M.ulcerans_Agy99           MVVADADLTPALVAREVTGLLTDPPRLAAMTAAAAQVGHRDAAAQVAQAA
MAV_2336|M.avium_104                MVVADADLTPELVAREVAGLVGDPPRLAAMTTAAARVGHPDAARRVAQAA
Mb2177c|M.bovis_AF2122/97           MVVADAALTPELVARQVAGLLTDPARLAAMTAAAARVGHRDAAGQVARAA
Rv2153c|M.tuberculosis_H37Rv        MVVADAALTPELVARQVAGLLTDPARLAAMTAAAARVGHRDAAGQVARAA
MLBr_00914|M.leprae_Br4923          LVVADADLTPGLVARQVVRLFSDPAQLAAMTAAAARVGHRDAAHHVAKVA
MAB_2006|M.abscessus_ATCC_1997      VIVADRDLTPESLAHMVIEMVSDPAKLAAMTSAAALSGHPEAARQVAQVA
TH_1477|M.thermoresistible__bu      LLIDDADLGPDLVADTVIGLLTDPARLAAMTTAAALAGHRDAAEQVAKVA
MSMEG_4227|M.smegmatis_MC2_155      LLVDDADLSGDTVARTVIPLLTDDSKLAAMTAAASLSGHPDAARRVAQVA
Mflv_2988|M.gilvum_PYR-GCK          LVVDDASLTPQFVAGTVAGLLNDPDRLATMTAAAALAGHPDAARRVAEVA
Mvan_3523|M.vanbaalenii_PYR-1       ILVEDRSLTPEFVAETVPGLLNNADTLAAMTAAAALAGHPDAARRVAEVA
                                    ::: *  *    :*  *  :. :   **:**:**:  ** :** :**..*

MMAR_3193|M.marinum_M               LDIARLAPS--RRRAVGGRR-------------
MUL_3501|M.ulcerans_Agy99           LDIARLAPS--RRRAVGGRR-------------
MAV_2336|M.avium_104                LDIGRTARR--ARGATGGRP-------------
Mb2177c|M.bovis_AF2122/97           LAVATGAG---ARTTT-----------------
Rv2153c|M.tuberculosis_H37Rv        LAVATGAG---ARTTT-----------------
MLBr_00914|M.leprae_Br4923          LDLARAERDTASGRSAGGKP-------------
MAB_2006|M.abscessus_ATCC_1997      LDVARERRS----RERGGRR-------------
TH_1477|M.thermoresistible__bu      LEVARDGRR--ARDGSAGRVVRRTSRSRREGGR
MSMEG_4227|M.smegmatis_MC2_155      LEIARAARK--KAS-------------------
Mflv_2988|M.gilvum_PYR-GCK          LDVARGTGS--RR--------------------
Mvan_3523|M.vanbaalenii_PYR-1       LEVARRARD--LRTRR-----------------
                                    * :.