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NKGSRDNNHSDRGISVVLAGGGTAGHVEPAMAVADALRALDPDVRITALGTQRGLETRLVPQRGYDLELI TPVPLPRKPSKDLLRLPMRVRTAIRQTRDVLTGVNADVVVGFGGYVALPAYLAARGGLTGRRKVPVVVHE ANARAGLANRVGARSARRVLSAVPDSGLRNVEVVGVPVRESITSLDRAALRAQARAEFGFAEDARVLLVF GGSQGAQSINRAVSAAAKDLAAAGISVLHAHGPKNTLDLPPADPQAPPYVAVPYLDRMDLAYAAADLAIC RSGAMTVAEVTAVGLPAIYVPLPIGNGEQRLNALPVVDAGGGLLVDDADLSGDTVARTVIPLLTDDSKLA AMTAAASLSGHPDAARRVAQVALEIARAARKKAS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4227 | murG | - | 100% (385) | N-acetylglucosaminyl transferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2177c | murG | 1e-150 | 75.88% (369) | undecaprenyldiphospho-muramoylpentapeptide beta-N- |
| M. gilvum PYR-GCK | Mflv_2988 | murG | 1e-161 | 80.38% (367) | N-acetylglucosaminyl transferase |
| M. tuberculosis H37Rv | Rv2153c | murG | 1e-150 | 75.88% (369) | undecaprenyldiphospho-muramoylpentapeptide beta-N- |
| M. leprae Br4923 | MLBr_00914 | murG | 1e-151 | 74.93% (371) | undecaprenyldiphospho-muramoylpentapeptide beta-N- |
| M. abscessus ATCC 19977 | MAB_2006 | murG | 1e-161 | 77.36% (371) | undecaprenyldiphospho-muramoylpentapeptide beta-N- |
| M. marinum M | MMAR_3193 | murG | 1e-154 | 77.33% (375) | UDP-N-acetylglucosamine-N-acetylmuramyl- (pentapeptide) |
| M. avium 104 | MAV_2336 | murG | 1e-158 | 78.26% (368) | N-acetylglucosaminyl transferase |
| M. thermoresistible (build 8) | TH_1477 | - | 1e-164 | 80.32% (376) | Probable UPD-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide) |
| M. ulcerans Agy99 | MUL_3501 | murG | 1e-154 | 76.80% (375) | undecaprenyldiphospho-muramoylpentapeptide beta-N- |
| M. vanbaalenii PYR-1 | Mvan_3523 | murG | 1e-162 | 80.32% (371) | N-acetylglucosaminyl transferase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3193|M.marinum_M MNDTVREPTGGLGV-NHGPA---------------LSVVLAGGGTAGHVE
MUL_3501|M.ulcerans_Agy99 MNDTVREPAGGLGV-NHGPA---------------LSVVLAGGGTAGHVE
MAV_2336|M.avium_104 MNDTVKKPTGGRGD-DPLPAGAALSAVAPH---EPVSVVLAGGGTAGHVE
Mb2177c|M.bovis_AF2122/97 MKDTVSQPAGGRGATAPRPADAASPSCGSSPSADSLSVVLAGGGTAGHVE
Rv2153c|M.tuberculosis_H37Rv MKDTVSQPAGGRGATAPRPADAASPSCGSSPSADSVSVVLAGGGTAGHVE
MLBr_00914|M.leprae_Br4923 MNNSVREPTRGRRG-SPPVADAALSVN------PPLSVVLAGGGTAGHVE
MAB_2006|M.abscessus_ATCC_1997 MSDELRP----------------------------LSVVLAGGGTAGHVE
MSMEG_4227|M.smegmatis_MC2_155 MNKG---------------SRDNNHSD------RGISVVLAGGGTAGHVE
TH_1477|M.thermoresistible__bu MPD----------------PEDREMVD------REISVVLAGGGTAGHVE
Mflv_2988|M.gilvum_PYR-GCK MT-------------GISVPAGQARRD------RAISVVLAGGGTAGHIE
Mvan_3523|M.vanbaalenii_PYR-1 MTRISVPAGQERNDGGISVPAGQERSD------RGISVVLAGGGTAGHIE
* :************:*
MMAR_3193|M.marinum_M PAMAVADALSVLEPNVRITALGTARGLETRLVPARGYHLELITPVPLPRK
MUL_3501|M.ulcerans_Agy99 PAMAVADALSVLEPNVRITALGTSRGLETRLVPARGYHLELITPVPLPRK
MAV_2336|M.avium_104 PAMAVADALKALDPNVRITSLGTARGLETRLVPERGYDLELITPVPLPRK
Mb2177c|M.bovis_AF2122/97 PAMAVADALVALDPRVRITALGTPRGLETRLVPQRGYHLELITAVPMPRK
Rv2153c|M.tuberculosis_H37Rv PAMAVADALVALDPRVRITALGTLRGLETRLVPQRGYHLELITAVPMPRK
MLBr_00914|M.leprae_Br4923 PAMAVADALRALDPQVRITALGTSRGLETRLVPERGYHLELITPVPLPRK
MAB_2006|M.abscessus_ATCC_1997 PAMAVADALREIDPTVRITALGTERGLETRLVPDRGYHLELIVPVPLPRR
MSMEG_4227|M.smegmatis_MC2_155 PAMAVADALRALDPDVRITALGTQRGLETRLVPQRGYDLELITPVPLPRK
TH_1477|M.thermoresistible__bu PAMAVADALTALEPGVRITALGTHRGLETRLVPERGYRLELITPVPLPRK
Mflv_2988|M.gilvum_PYR-GCK PAMAVADALTALEPNVRITALGTARGLETRLVPQRGYDLELITPVPLPRK
Mvan_3523|M.vanbaalenii_PYR-1 PAMAVADALTALDPDVRITALGTERGLETRLVPQRGYHLELITLVPLPRK
********* ::* ****:*** ********* *** ****. **:**:
MMAR_3193|M.marinum_M PSGDLARLPPRVWRAVRETRAVLDLVDADVVIGFGGYVALPAYLAARGIP
MUL_3501|M.ulcerans_Agy99 PSGDLARLPPRVWRSVRETRAVLDLVDADVVIGFGGYVALPAYLAARGIP
MAV_2336|M.avium_104 PTGDLARLPSRVWRAVRETRAVLHAVDADVVIGFGGYVALPAYLAARGVS
Mb2177c|M.bovis_AF2122/97 PGGDLARLPSRVWRAVREARDVLDDVDADVVVGFGGYVALPAYLAARGLP
Rv2153c|M.tuberculosis_H37Rv PGGDLARLPSRVWRAVREARDVLDDVDADVVVGFGGYVALPAYLAARGLP
MLBr_00914|M.leprae_Br4923 LTGDLARLPLRVWRAVRETRAVFEVVEAHVVVGFGGYVALPAYLAARGIP
MAB_2006|M.abscessus_ATCC_1997 LTGDLVRLPLRVRRAVRQTRAVFDGVQADVVIGFGGYVALPAYLAARRGP
MSMEG_4227|M.smegmatis_MC2_155 PSKDLLRLPMRVRTAIRQTRDVLTGVNADVVVGFGGYVALPAYLAARGGL
TH_1477|M.thermoresistible__bu PTADLARLPLRVRRAVRETRAVLDAVRADVVIGFGGYVALPAYLAARGGL
Mflv_2988|M.gilvum_PYR-GCK LSADLLRLPMRVRRAVRETRAVFEAVDADVVIGFGGYVALPAYLAAR---
Mvan_3523|M.vanbaalenii_PYR-1 LSADLFRLPMRVLRAVRQTRRILDEVSADVVVGFGGYVAVPAYLAARS-L
** *** ** ::*::* :: * *.**:*******:*******
MMAR_3193|M.marinum_M G---LRRRIPVVIHEANARAGLANRVGLRTADRVLSAVPDSGLRGAEVVG
MUL_3501|M.ulcerans_Agy99 G---LRRRIPVVIHEANARAGLANRVGLRTADRVLSAVPDSGLRGAEVVG
MAV_2336|M.avium_104 P---RKPRVPVVIHEANASAGLANRVGARTAQRVLSAVADCGLPGAEVVG
Mb2177c|M.bovis_AF2122/97 LPPRRRRRIPVVIHEANARAGLANRVGAHTADRVLSAVPDSGLRRAEVVG
Rv2153c|M.tuberculosis_H37Rv LPPRRRRRIPVVIHEANARAGLANRVGAHTADRVLSAVPDSGLRRAEVVG
MLBr_00914|M.leprae_Br4923 R---VRRRIPVVVHEANARAGIANRVGVRTAERVLSAVPGSGLRGAEVVG
MAB_2006|M.abscessus_ATCC_1997 L---RRRRVPVVIHEANARAGLANRVGARGAQRVLSAVPDSGLRDAEVVG
MSMEG_4227|M.smegmatis_MC2_155 T---GRRKVPVVVHEANARAGLANRVGARSARRVLSAVPDSGLRNVEVVG
TH_1477|M.thermoresistible__bu R---RRSAVPVVVHEANAHAGWANRVGARAAQRVLSAVPDPGLGPVEVVG
Mflv_2988|M.gilvum_PYR-GCK ------RRVPVVVHEANASAGWANKVGARVATRVLSAVPDPGLGHVDVVG
Mvan_3523|M.vanbaalenii_PYR-1 R---THRRVPVVVHEANASAGWANKVGARSAQRVLSAVPDPGLPHVEVVG
:***:***** ** **:** : * ******.. ** .:***
MMAR_3193|M.marinum_M VPVRAAITALDRMALRAEARAHFGFADDARVLLVFGGSQGAVSLNKAVSA
MUL_3501|M.ulcerans_Agy99 VPVRAAITALDRMALRAEARAHFGFADDARVLLVFGGSQGAVSLNKAVSA
MAV_2336|M.avium_104 VPVREAITSLDRAAVRAEARRHFGFADDARVLLVFGGSQGAASLNRAVSG
Mb2177c|M.bovis_AF2122/97 VPVRASIAALDRAVLRAEARAHFGFPDDARVLLVFGGSQGAVSLNRAVSG
Rv2153c|M.tuberculosis_H37Rv VPVRASIAALDRAVLRAEARAHFGFPDDARVLLVFGGSQGAVSLNRAVSG
MLBr_00914|M.leprae_Br4923 VPIHATITTLNRPALRADARKHFGFTDDARVLLVFGGSQGAVSLNRAVAG
MAB_2006|M.abscessus_ATCC_1997 VPVRGSITALDRAALRHQARAHYGFDDDALVLLVFGGSQGAVSLNNAVSA
MSMEG_4227|M.smegmatis_MC2_155 VPVRESITSLDRAALRAQARAEFGFAEDARVLLVFGGSQGAQSINRAVSA
TH_1477|M.thermoresistible__bu VPLRSSITSMDRHALRAEARACFGFDADARVLLVFGGSQGAQSINRAVAA
Mflv_2988|M.gilvum_PYR-GCK VPVREAITSLDRSALRAEARAHFGFADDARVLLVFGGSQGAQSLNRAVSG
Mvan_3523|M.vanbaalenii_PYR-1 VPVREAITSLDRMALRAEARAHFGFADDARVLLVFGGSQGAQSLNRAVAG
**:: :*::::* .:* :** :** ** *********** *:*.**:.
MMAR_3193|M.marinum_M AAAELAASGVSVLHAHGPKNVLELLAPRTPGQDDPPYVAVPYLDRMDLAY
MUL_3501|M.ulcerans_Agy99 AAAELAASGVSVLHAHGPKNVLELLAPRTPDQDDPPYVAVPYLDRMDLAY
MAV_2336|M.avium_104 AAAQLAAAGVSVLHAHGPKNTLDLREPQP---GDPPYVAVPYLDRMDLAY
Mb2177c|M.bovis_AF2122/97 AAADLAAAGVCVLHAHGPQNVLELRRRAQ---GDPPYVAVPYLDRMELAY
Rv2153c|M.tuberculosis_H37Rv AAADLAAAGVCVLHAHGPQNVLELRRRAQ---GDPPYVAVPYLDRMELAY
MLBr_00914|M.leprae_Br4923 AAEDLAASGVAVLHAYGLKNTLELRTPEY---GEPPYVAVPYLDRMDLAY
MAB_2006|M.abscessus_ATCC_1997 AANDLAAAGVSVLHAHGPKNTIKLPERPP---GAPRYVALPYLDRMDLAY
MSMEG_4227|M.smegmatis_MC2_155 AAKDLAAAGISVLHAHGPKNTLDLPPADP---QAPPYVAVPYLDRMDLAY
TH_1477|M.thermoresistible__bu AARRLAAAGISVLHAHGPKNTLQLPAPAD---GAPPYVAVPYLDRMDLAY
Mflv_2988|M.gilvum_PYR-GCK AAEGLAAAGISVLHAHGPKNTLDLRAPRP---GDPPYVAVPYLERMDLAY
Mvan_3523|M.vanbaalenii_PYR-1 AAEKLAEQGISVLHAHGPKNTLDLPAPRP---GDPPYVAVPYLERMDLAY
** ** *:.****:* :*.:.* * ***:***:**:***
MMAR_3193|M.marinum_M AAADLVICRSGAMTVAEVSAVGLPAIYVPLPIGNGEQRLNALPVVNAGGG
MUL_3501|M.ulcerans_Agy99 AAADLVICRSGAMTVAEVSAVGLPAIYVPLPIGNGEQRLNALPVVNAGGG
MAV_2336|M.avium_104 AAADLVICRSGAMTVAEVSAVGLPAIYVPLPIGNGEQRLNALPVVNAGGG
Mb2177c|M.bovis_AF2122/97 AAADLVICRAGAMTVAEVSAVGLPAIYVPLPIGNGEQRLNALPVVNAGGG
Rv2153c|M.tuberculosis_H37Rv AAADLVICRAGAMTVAEVSAVGLPAIYVPLPIGNGEQRLNALPVVNAGGG
MLBr_00914|M.leprae_Br4923 AAADLVICRSGAMTVAEVSAVGLPAIYVPFPIGNGEQRLNALPVVNAGGG
MAB_2006|M.abscessus_ATCC_1997 AAADIAVCRSGAMTVAEVSAVGLPAIYVPLPIGNGEQRLNALPIVDAGGG
MSMEG_4227|M.smegmatis_MC2_155 AAADLAICRSGAMTVAEVTAVGLPAIYVPLPIGNGEQRLNALPVVDAGGG
TH_1477|M.thermoresistible__bu AAADLAICRSGAMTVAEVSAVGLPAIYVPLPIGNGEQRFNALPVVQAGGG
Mflv_2988|M.gilvum_PYR-GCK AAADLAVCRSGAMTVAEVSAVGLPAVYVPLPIGNGEQRLNALPVVEAGGG
Mvan_3523|M.vanbaalenii_PYR-1 AAADLAVCRSGAMTVAEVSAVGLPAVYVPLPIGNGEQRLNALPVVEAGGG
****:.:**:********:******:***:********:****:*:****
MMAR_3193|M.marinum_M MVVADADLTPALVAREVTGLLTDPPRLAAMTAAAAQVGHRDAAAQVAQAA
MUL_3501|M.ulcerans_Agy99 MVVADADLTPALVAREVTGLLTDPPRLAAMTAAAAQVGHRDAAAQVAQAA
MAV_2336|M.avium_104 MVVADADLTPELVAREVAGLVGDPPRLAAMTTAAARVGHPDAARRVAQAA
Mb2177c|M.bovis_AF2122/97 MVVADAALTPELVARQVAGLLTDPARLAAMTAAAARVGHRDAAGQVARAA
Rv2153c|M.tuberculosis_H37Rv MVVADAALTPELVARQVAGLLTDPARLAAMTAAAARVGHRDAAGQVARAA
MLBr_00914|M.leprae_Br4923 LVVADADLTPGLVARQVVRLFSDPAQLAAMTAAAARVGHRDAAHHVAKVA
MAB_2006|M.abscessus_ATCC_1997 VIVADRDLTPESLAHMVIEMVSDPAKLAAMTSAAALSGHPEAARQVAQVA
MSMEG_4227|M.smegmatis_MC2_155 LLVDDADLSGDTVARTVIPLLTDDSKLAAMTAAASLSGHPDAARRVAQVA
TH_1477|M.thermoresistible__bu LLIDDADLGPDLVADTVIGLLTDPARLAAMTTAAALAGHRDAAEQVAKVA
Mflv_2988|M.gilvum_PYR-GCK LVVDDASLTPQFVAGTVAGLLNDPDRLATMTAAAALAGHPDAARRVAEVA
Mvan_3523|M.vanbaalenii_PYR-1 ILVEDRSLTPEFVAETVPGLLNNADTLAAMTAAAALAGHPDAARRVAEVA
::: * * :* * :. : **:**:**: ** :** :**..*
MMAR_3193|M.marinum_M LDIARLAPS--RRRAVGGRR-------------
MUL_3501|M.ulcerans_Agy99 LDIARLAPS--RRRAVGGRR-------------
MAV_2336|M.avium_104 LDIGRTARR--ARGATGGRP-------------
Mb2177c|M.bovis_AF2122/97 LAVATGAG---ARTTT-----------------
Rv2153c|M.tuberculosis_H37Rv LAVATGAG---ARTTT-----------------
MLBr_00914|M.leprae_Br4923 LDLARAERDTASGRSAGGKP-------------
MAB_2006|M.abscessus_ATCC_1997 LDVARERRS----RERGGRR-------------
MSMEG_4227|M.smegmatis_MC2_155 LEIARAARK--KAS-------------------
TH_1477|M.thermoresistible__bu LEVARDGRR--ARDGSAGRVVRRTSRSRREGGR
Mflv_2988|M.gilvum_PYR-GCK LDVARGTGS--RR--------------------
Mvan_3523|M.vanbaalenii_PYR-1 LEVARRARD--LRTRR-----------------
* :.