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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_1445 | - | 100% (251) | CONSERVED HYPOTHETICAL PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2414 | - | 1e-70 | 59.32% (236) | hypothetical protein Mb2414 |
| M. gilvum PYR-GCK | Mflv_2684 | - | 8e-75 | 63.68% (234) | cobalamin (vitamin B12) biosynthesis CbiX protein |
| M. tuberculosis H37Rv | Rv2393 | - | 1e-70 | 59.32% (236) | hypothetical protein Rv2393 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1658c | - | 6e-48 | 46.55% (232) | hypothetical protein MAB_1658c |
| M. marinum M | MMAR_3712 | - | 2e-69 | 56.17% (235) | hypothetical protein MMAR_3712 |
| M. avium 104 | MAV_2152 | - | 2e-69 | 60.43% (235) | secreted protein |
| M. smegmatis MC2 155 | MSMEG_4529 | - | 3e-97 | 77.63% (228) | secreted protein |
| M. ulcerans Agy99 | MUL_2697 | - | 1e-69 | 60.17% (236) | hypothetical protein MUL_2697 |
| M. vanbaalenii PYR-1 | Mvan_3859 | - | 6e-73 | 62.66% (233) | cobalamin (vitamin B12) biosynthesis CbiX protein |
CLUSTAL 2.0.9 multiple sequence alignment
TH_1445|M.thermoresistible__bu ------------------------------VTRALAPAPASVAGPPALIL
MSMEG_4529|M.smegmatis_MC2_155 ---------------------------------------------MTLVL
Mflv_2684|M.gilvum_PYR-GCK ---------------------------------------------MTLIL
Mvan_3859|M.vanbaalenii_PYR-1 ---------------------------------------------MTLIL
MAV_2152|M.avium_104 MST--------------------------------------------LVL
MUL_2697|M.ulcerans_Agy99 MST--------------------------------------------LVL
Mb2414|M.bovis_AF2122/97 MTAPATMQSAAMLRSGAIEAPPATMQSAAMRWGHLPLAEESGTIAPQLVL
Rv2393|M.tuberculosis_H37Rv MTAPATMQSAAMLRSGAIEAPPATMQSAAMRWGHLPLAEESGTIAPQLVL
MMAR_3712|M.marinum_M MTA--------------------------------------------LVL
MAB_1658c|M.abscessus_ATCC_199 ------------------------------------------MRNPTLVA
*:
TH_1445|M.thermoresistible__bu TAHGSADPRSAANAHAIAGHLRRLAPDVEVRVAFCEQNTPNLADVLAQMR
MSMEG_4529|M.smegmatis_MC2_155 TAHGSADPRSSANAHAIAGHVRRLLPDTEVRVAFCEQNEPNLADVLTAVE
Mflv_2684|M.gilvum_PYR-GCK TAHGSADPRSAATARSIVECIRRLRPDLDARIAFCEQNSPNLRDVLADLP
Mvan_3859|M.vanbaalenii_PYR-1 TAHGSADPRSAQTARAIVDCIRCLRPTLDARIAFCEQSSPNLRDELAALR
MAV_2152|M.avium_104 TAHGSRDPRSAANAEAVADRLRRMRPGLDVRLAFLELNAPNFVDVLAGLP
MUL_2697|M.ulcerans_Agy99 TAHGSRDPRSADNARAVAAALRRMRPNLDVRLAFLELCAPNFVDVLAELP
Mb2414|M.bovis_AF2122/97 TAHGSKDPRSAANARAIAGRLARMRPGLDVRVAFCELNSPNLVDVLNRCR
Rv2393|M.tuberculosis_H37Rv TAHGSKDPRSAANARAIAGRLARMRPGLDVRVAFCELNSPNLVDVLNRCR
MMAR_3712|M.marinum_M TAHGSRDPRSSANARAVAARVARMRPDLDVRLAFCELNSPGLVEVLNGCS
MAB_1658c|M.abscessus_ATCC_199 VAHGSRDARFAQNARRVVRQVRSLRPDLDVRLAFLELSEPNLLDVLGDLS
.**** *.* : .*. :. : : * :.*:** * *.: : *
TH_1445|M.thermoresistible__bu T-G-AVVVPLLLARAYHARVDIPELIAAS--GADVAQADVLGADPRLLHV
MSMEG_4529|M.smegmatis_MC2_155 A-G-SVVVPLLLASAYHARIDIPALIAQT--GADVVQADVLGNDPRLLQV
Mflv_2684|M.gilvum_PYR-GCK G-RHGVVVPLLLADAYHARVDIPQMIADS--GADVRQAAVLGEDERLIHV
Mvan_3859|M.vanbaalenii_PYR-1 R-RQAVVVPLLLADAYHARVDIPEMIAAS--GADVRQAGVLGEDDRLIHV
MAV_2152|M.avium_104 DSRRAVVAPLLLASAYHARLDIPEQIARA-GAHGIRQADVLGEDDRLVAV
MUL_2697|M.ulcerans_Agy99 DSQRAVVTPLLLASAYHARTDIPEQIARS-GALGVREAAVLGEDDRLVSV
Mb2414|M.bovis_AF2122/97 G--AAVVTPLLLADAYHARVDIPAQIASCRVGHRVRQASVLGEDIRLVSA
Rv2393|M.tuberculosis_H37Rv G--AAVVTPLLLADAYHARVDIPAQIASCRVGHRVRQASVLGEDIRLVSA
MMAR_3712|M.marinum_M G--DAVVTPLLLANGYHAGIDIPAQIASCRESLRVRQANVLGTDDRLVSV
MAB_1658c|M.abscessus_ATCC_199 G--DAVVVPLLLSDAYHARIDLPTVLSAAPARLRVMQACVLGADNRLLAL
.**.****: .*** *:* :: : :* *** * **:
TH_1445|M.thermoresistible__bu MRGRLSALGVSRFDAGLGVVMVGVGSSHADANARTAAVAQALGEGTRWTG
MSMEG_4529|M.smegmatis_MC2_155 MRERLTALGVSRFDSSLGVVLTGVGSSHAAANARTAELAADLAEGTRWVG
Mflv_2684|M.gilvum_PYR-GCK LRQRLEHAGVSRLDPRVGILVTAVGSSRAAANANTEAVARELTLTTRWA-
Mvan_3859|M.vanbaalenii_PYR-1 LRQRLEHAGVSRLDPSVGVIVTAVGSSRPAANVRTATVARELTLTTRWT-
MAV_2152|M.avium_104 LRGRLAEIGVSPLDDDLGVMVVAIGSSNTAANARTAKVASRLAAGTRWAC
MUL_2697|M.ulcerans_Agy99 LRDRLAERGVSPRDRNIGVLVVAVGSSHAPVNARTARVAAKLGAGTRWAG
Mb2414|M.bovis_AF2122/97 LHERLTELGVSPFDHTLGVVVLAIGSSHPAANARTSTVASRLAEGTQWAA
Rv2393|M.tuberculosis_H37Rv LHERLTELGVSPFDHTLGVVVLAIGSSHPAANARTSTVASRLAEGTQWAA
MMAR_3712|M.marinum_M LRQRVTALGVSRFDDGLGVLVVAIGSSNAAVNSHTAQVGPKLAEGTRWAA
MAB_1658c|M.abscessus_ATCC_199 ARRRVTELGIAHP----GVILSAVGSSDSTANTRTRALA------AQWPI
: *: *:: *::: .:*** . .* .* :. ::*
TH_1445|M.thermoresistible__bu VEVAFATGPAPSVPDAVARLRARGADRIAISPWFLAHGRITDRVAGFARG
MSMEG_4529|M.smegmatis_MC2_155 THVAFATGQDPSVSRAVERLRARGATRLVIAPWFLAHGRITDRVAEYARR
Mflv_2684|M.gilvum_PYR-GCK ATTAFATGPQPSLTDAAAHLRALGASRLVIAPWFLAHGRITDRVAAFARA
Mvan_3859|M.vanbaalenii_PYR-1 ATTAFATGPHPSPAEAADELRRRGATRLVIAPWFLAHGRITDRVADFAAA
MAV_2152|M.avium_104 ATTAFATRPEASVARAADQLRRRGARRLVIAPWFLAPGFITDGVSTFARD
MUL_2697|M.ulcerans_Agy99 TTMAFATGPKPSVADAAAQLRASGARRLVIAPWFLAPGLITDRVWKYACD
Mb2414|M.bovis_AF2122/97 VTTAFITRPEASLADATDRLRRHGARRMVIAPWLLAPGILSDRVRGYARE
Rv2393|M.tuberculosis_H37Rv VTTAFITRPEASLADATDRLRRHGARRMVIAPWLLAPGILSDRVRGYARE
MMAR_3712|M.marinum_M VATAFATHPPAALAEAVSRLRRRGAHRVVVAPWFLAHGRLPDRVQRFAAD
MAB_1658c|M.abscessus_ATCC_199 STTVFATGDPTSLAEAAESLRARGATDIVVAPWFLSPGLLLDRVRAEAAQ
.* * .: . *. ** ** :.::**:*: * : * * *
TH_1445|M.thermoresistible__bu AGIPMAEPLGPHRLVAATVLDRYEETVAA--AALAA
MSMEG_4529|M.smegmatis_MC2_155 EGIPMAEPLGPHRLVAATVLDRYEEAIEARTAGFAA
Mflv_2684|M.gilvum_PYR-GCK HDIPMSAPLGAHRQVAETVLDRFDAALVHRAAA---
Mvan_3859|M.vanbaalenii_PYR-1 QRIPMSAPLGAHRQVAETVLDRFDAALAVHAAA---
MAV_2152|M.avium_104 NGIRMAAPLGAHRLVAETVLDRYDEALSA-DAAA--
MUL_2697|M.ulcerans_Agy99 NDIAMARPMGAHPLVAQTVLDRYDQALAAGDAAA--
Mb2414|M.bovis_AF2122/97 AGIAMAQPLGAHPMVAATMWDRYRQAVAGRIAA---
Rv2393|M.tuberculosis_H37Rv AGIAMAQPLGAHPMVAATMWDRYRQAVAGRIAA---
MMAR_3712|M.marinum_M TGLAMAAPLGAHRLVAETVLDRFAQATAGRVAA---
MAB_1658c|M.abscessus_ATCC_199 LDMPVAAPLGADRLVADVVVQRYASAIAAPVPTPH-
: :: *:*.. ** .: :*: : .