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M. thermoresistible (build 8) TH_1400 ()

annotation: PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
coordinates: 2642785 - 2644020
length: 412

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1400-100% (412)PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
M. thermoresistible (build 8)TH_4008-6e-0536.92% (65) PUTATIVE Trypsin

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2894c-1e-17372.82% (412) transmembrane protein
M. gilvum PYR-GCKMflv_4082-0.075.97% (412) peptidase M50
M. tuberculosis H37RvRv2869c-1e-17272.57% (412) transmembrane protein
M. leprae Br4923MLBr_01582-1e-16669.66% (412) putative integral membrane protein
M. abscessus ATCC 19977MAB_3170c-1e-14160.86% (419) protease/peptidase
M. marinum MMMAR_1837-1e-17372.33% (412) transmembrane protein
M. avium 104MAV_3726-1e-17372.53% (415) peptidase M50
M. smegmatis MC2 155MSMEG_2579-0.076.46% (412) zinc metalloprotease
M. ulcerans Agy99MUL_2086-1e-17372.33% (412) transmembrane protein
M. vanbaalenii PYR-1Mvan_2261-0.075.49% (412) peptidase M50

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4082|M.gilvum_PYR-GCK          -MMYVLGVTLFALAILVSVALHECGHMWVARATGMKVRRYFVGFGPTLWS
Mvan_2261|M.vanbaalenii_PYR-1       -MMYVLGVTLFALAILVSVALHECGHMWVARATGMKVRRYFVGFGPTLWS
TH_1400|M.thermoresistible__bu      -MMFAIGVALFALAILVSVALHECGHMWVARATGMKVRRYFVGFGPTLWS
MSMEG_2579|M.smegmatis_MC2_155      -MMFGIGIVLFALAILVSVALHECGHMWVARATGMKVRRYFVGFGPTLWS
MLBr_01582|M.leprae_Br4923          -MMFALGIVLFAIAILISVALHECGHLWVACATGMKVRRYFVGFGPTLWS
MAV_3726|M.avium_104                -MMFVIGIVLFALAILISVALHECGHMWVARATGMKVRRYFVGFGPTLWS
Mb2894c|M.bovis_AF2122/97           -MMFVTGIVLFALAILISVALHECGHMWVARRTGMKVRRYFVGFGPTLWS
Rv2869c|M.tuberculosis_H37Rv        -MMFVTGIVLFALAILISVALHECGHMWVARRTGMKVRRYFVGFGPTLWS
MMAR_1837|M.marinum_M               -MMFVVGIVLFALAILISVALHECGHMWVARATGMKVRRYFVGFGPTLWS
MUL_2086|M.ulcerans_Agy99           -MMFVVGIVLFALAILISVALHECGHMWVARATGMKVRRYFVGFGPTLWS
MAB_3170c|M.abscessus_ATCC_199      MAAYAIGIALFALAILVSVALHECGHMWVAQATGMKVRRYFVGFGPTLWS
                                       :  *:.***:***:*********:***  ******************

Mflv_4082|M.gilvum_PYR-GCK          TRRPNKL-------GETEYGIKAVPLGGFCDIAGMTAVEELDPADRPYAM
Mvan_2261|M.vanbaalenii_PYR-1       TWRPNKL-------GQTEYGVKAIPLGGFCDIAGMTAVEELDPEDRPYAM
TH_1400|M.thermoresistible__bu      THRPNRL-------GSTEYGIKAVPLGGFCDIAGMTAIDELKPDEQPYAM
MSMEG_2579|M.smegmatis_MC2_155      TRRANRL-------GSTEYGIKAIPLGGFCDIAGMTSVDEIAPEDRPYAM
MLBr_01582|M.leprae_Br4923          TRR-----------GETQYGIKAVPLGGFCDIVGMTSVEKLEPDESDRAM
MAV_3726|M.avium_104                TRR-----------GETEYGLKAVPLGGFCDIAGMTSVEELAPDEADRAM
Mb2894c|M.bovis_AF2122/97           TRR-----------GETEYGVKAVPLGGFCDIAGMTPVEELDPDERDRAM
Rv2869c|M.tuberculosis_H37Rv        TRR-----------GETEYGVKAVPLGGFCDIAGMTPVEELDPDERDRAM
MMAR_1837|M.marinum_M               TRR-----------GETEYGVKAIPAGGFCDIAGMTPVEDLEPDEHDRAM
MUL_2086|M.ulcerans_Agy99           TRR-----------GETEYGVKAIPAGGFCDIAGMTPVEDLEPDEHDRAM
MAB_3170c|M.abscessus_ATCC_199      TKRKSNRPNKQGANDIVEYGVKAVPLGGFCDIAGMTSVEELTPEESDRAM
                                    * *           . .:**:**:* ******.***.::.: * :   **

Mflv_4082|M.gilvum_PYR-GCK          YRQKTWKRVAVLFAGPAMNFIIGLVLIYGIAIVWGLPNITAPTTAVVGET
Mvan_2261|M.vanbaalenii_PYR-1       YKQKTWKRVAVLFAGPAMNFVIGLVLIYAIALIWGLPNITAPTTAVVGET
TH_1400|M.thermoresistible__bu      YRQKTWKRVAVLFAGPGMNFVIGLVLIYAIAVIWGLPTLNPPTTAVVGET
MSMEG_2579|M.smegmatis_MC2_155      YKQKVWKRVAVLFAGPAMNFVIGLVLIYGIAIVWGLPNLHQPTTAIVGET
MLBr_01582|M.leprae_Br4923          YKQATWKRVAVLFAGPAMNFVICLVLIYGIALVWGLPNLHMPTRAVIGET
MAV_3726|M.avium_104                FKQATWKRVAVLFAGPGANFVICLVLLYAIALIWGLPNLHPPTKAIVGET
Mb2894c|M.bovis_AF2122/97           YKQATWKRVAVLFAGPGMNLAICLVLIYAIALVWGLPNLHPPTRAVIGET
Rv2869c|M.tuberculosis_H37Rv        YKQATWKRVAVLFAGPGMNLAICLVLIYAIALVWGLPNLHPPTRAVIGET
MMAR_1837|M.marinum_M               YKQATWKRVAVLFAGPGMNFVICLVLIYGIAVVWGLPNLHPPTQAIIGET
MUL_2086|M.ulcerans_Agy99           YKQATWKRVAVLFAGPGMNFVICLVLIYGIAVVWGLPNLHPPTQAIIGET
MAB_3170c|M.abscessus_ATCC_199      YKQKVWKRVAVLFAGPAMNFLIGIVVFYGVVLFWGLPDNNAPTHPEITQT
                                    ::* .***********. *: * :*::*.:.:.****    ** . : :*

Mflv_4082|M.gilvum_PYR-GCK          SCIKSEVTQG--ELGDCVANSPAAAAGIEAGDVIVRVGDTEVPTFDALVE
Mvan_2261|M.vanbaalenii_PYR-1       SCIKSEVSQG--ELGDCVANSPAAAAGIQAGDVIVKVGDTEVPTFDALVE
TH_1400|M.thermoresistible__bu      SCVAAEVRQG--ELSECSGPGPAALAGIQPGDVIVKVGDAEVADFTEMAT
MSMEG_2579|M.smegmatis_MC2_155      GCVAPQITLE--EMGECTGPGPAALAGIQAGDEIVKVGDTEVKDFAGMAA
MLBr_01582|M.leprae_Br4923          ACVASELDQG--KLGNCTGPGPAALAGLRAGDVVVKIGDTTVSTFDDMAA
MAV_3726|M.avium_104                ACVAPEVAPG--KLADCTGPGPAALAGIRPGDVIVKVGDTPVSTFDDMAA
Mb2894c|M.bovis_AF2122/97           GCVAQEVSQG--KLEQCTGPGPAALAGIRSGDVVVKVGDTPVSSFDEMAA
Rv2869c|M.tuberculosis_H37Rv        GCVAQEVSQG--KLEQCTGPGPAALAGIRSGDVVVKVGDTPVSSFDEMAA
MMAR_1837|M.marinum_M               GCVAPETAQG--KLEQCTGPGPAALAGLRAGDVVVKVGDTAVSTFDEMAT
MUL_2086|M.ulcerans_Agy99           GCVAPETAQG--KLEQCTGPGPAALAGLRAGDVVVKVGDTAVSTFGEMAT
MAB_3170c|M.abscessus_ATCC_199      SCVAPQKSADPRDVVACTGEGPAALAGLRAGDQVLTAGGTSVSTSTDLVT
                                    .*:  :      .:  * . .*** **:..** ::  *.: *     :. 

Mflv_4082|M.gilvum_PYR-GCK          AVRQESGPTVLTVQRDENGQVREFTTTVDVTPSQRYVAGEDGGPA---VP
Mvan_2261|M.vanbaalenii_PYR-1       AVRRQNGPTTLTVQRDENGEPREFTTTVDVTPSQRYVAGENGGPA---VP
TH_1400|M.thermoresistible__bu      AVRQHRGPTELTVQRTVDGVTTEFTTVVDVTPTQRFTAGEDGEP----VP
MSMEG_2579|M.smegmatis_MC2_155      AVRKLDGPTRIEFKRDG----RVMDTVVDVTPTQRFTSADASAP------
MLBr_01582|M.leprae_Br4923          VVRKLHGTVPIVFERDG----TAITSYVDITPTQRYMSKGKGSQ---LEP
MAV_3726|M.avium_104                AIRKVHGNVPIVVDRDG----TAITAYVDVTPTQRYLSGGSGPQGAPPQP
Mb2894c|M.bovis_AF2122/97           AVRKSHGSVPIVVERDG----TAIVTYVDIESTQRWIPNGQGGE---LQP
Rv2869c|M.tuberculosis_H37Rv        AVRKSHGSVPIVVERDG----TAIVTYVDIESTQRWIPNGQGGE---LQP
MMAR_1837|M.marinum_M               AIRKLHGSVPIVVERDG----TTVTANVVIESTRRWVPNEQGNQ---LEP
MUL_2086|M.ulcerans_Agy99           AIRKLHGSMPIVVERDG----TTVTANVVIESTRRWVPNEQGNQ---LEP
MAB_3170c|M.abscessus_ATCC_199      AIRGLRGPQVFEIVRDG----KPQSLMVNVTETQRWD--EKAGK-----L
                                    .:*   *   : . *            * :  ::*:     .        

Mflv_4082|M.gilvum_PYR-GCK          VDVGSIGVTAAQFG-PTQYNAFTAVPGTFVFTKDLAVELGKAVVKIPTKI
Mvan_2261|M.vanbaalenii_PYR-1       VDVGSIGVTAAQFG-PTQYNPLTAVPGTFVFTKDLAVALGKAIVKIPTKI
TH_1400|M.thermoresistible__bu      AEVGAIGVTAAQFG-PTQYNVLSAVPATFTFTGELAVELGKALAKIPTKV
MSMEG_2579|M.smegmatis_MC2_155      STVGAIGVSAVPVQPPAQYNPITAVPATFAFTGDLAVELGKSLAKIPTKI
MLBr_01582|M.leprae_Br4923          ATVGAIGVGAHHLL-PTHYGVFSALPATAAFAGDLTVEVGKALVTIPTKL
MAV_3726|M.avium_104                STVGAIGVGAVKVA-PAHYGVFSAIPASVVFAGDLTVEVGKALVTIPTKV
Mb2894c|M.bovis_AF2122/97           ATVGAIGVGAARVG-PVRYGVFSAMPATFAFTGDLTVEVGKALAALPTKV
Rv2869c|M.tuberculosis_H37Rv        ATVGAIGVGAARVG-PVRYGVFSAMPATFAVTGDLTVEVGKALAALPTKV
MMAR_1837|M.marinum_M               ATVGAIGVGAAQSG-PTQYGILSALPATFAFTGDLTVEVGRALVAIPTKV
MUL_2086|M.ulcerans_Agy99           ATVGAIGVGAAQSG-PTQYGILSALPATFAFTGDLTVEVGRALVAIPTKV
MAB_3170c|M.abscessus_ATCC_199      VPVGAVGASLSTYVPQKHYNPVTAIPATGNLIGTVAVETVKAIGKIPMKV
                                      **::*.         :*. .:*:*.:  .   ::*   :::  :* *:

Mflv_4082|M.gilvum_PYR-GCK          GALVDSISGGERDPETPISVVGASRIGGETVEAGIWVAFWFFLAQLNFVL
Mvan_2261|M.vanbaalenii_PYR-1       GALVHSITGGERDPETPISVVGASRIGGETVEHGIWVAFWFFLAQLNFVL
TH_1400|M.thermoresistible__bu      GALVASITGDERDPETPISVVGASIIGGDTVNHGLWVAFWFFLAQLNFVL
MSMEG_2579|M.smegmatis_MC2_155      GALVEAIGGGERDKETPISVVGASIIGGETVDAGLWVAFWFFLAQLNFVL
MLBr_01582|M.leprae_Br4923          GALVHAIGGGQRDPQTPMSVVGASIIGGDTVDHGLWVAFWFFLAQLNLIL
MAV_3726|M.avium_104                GALVHAIGGGQRDPQTPMSVVGASIIGGDTVDHGLWVAFWFFLAQLNLIL
Mb2894c|M.bovis_AF2122/97           GALVRAIGGGQRDPQTPISVVGASIIGGDTVDHGLWVAFWFFLAQLNLIL
Rv2869c|M.tuberculosis_H37Rv        GALVRAIGGGQRDPQTPISVVGASIIGGDTVDHGLWVAFWFFLAQLNLIL
MMAR_1837|M.marinum_M               GALVHAIGGGQRDPQTPISVVGASIIGGDTVDHGLWVAFWFFLAQLNLIL
MUL_2086|M.ulcerans_Agy99           GALVHAIGGGQRDPQTPISVVGASIIGGDTVDHGLWVAFWFFLAQLNLIL
MAB_3170c|M.abscessus_ATCC_199      GALWDSITGSERAMDTPMSIVGASRMGGETVEHDMWIMFWILLAQLNFAL
                                    ***  :* *.:*  :**:*:**** :**:**: .:*: **::*****: *

Mflv_4082|M.gilvum_PYR-GCK          GGINLVPLLPLDGGHISIALYEKVRNKIREARGKVAAAPVNYLKLMPLTY
Mvan_2261|M.vanbaalenii_PYR-1       GAVNLIPLLPLDGGHISIALYEKLRNKLREARGKVAAGPVNYLKLMPVTY
TH_1400|M.thermoresistible__bu      GAINLVPLLPFDGGHIAIATYEKIRNMIRSARGLTAAAPVNYLKLMPATY
MSMEG_2579|M.smegmatis_MC2_155      GAINLVPLLPFDGGHIAVATYEKIRNMIRSARGMVAAGPVNYLKLMPATY
MLBr_01582|M.leprae_Br4923          GAINLVPLLPFDGGHIAIAVFERIRNLIRSARGVVVAAPVNYLKLMPATY
MAV_3726|M.avium_104                GAINLVPLLPFDGGHIAIAVFEKVRNLIRSARGMVAAAPVNYLKLMPATY
Mb2894c|M.bovis_AF2122/97           AAINLLPLLPFDGGHIAVAVFERIRNMVRSARGKVAAAPVNYLKLLPATY
Rv2869c|M.tuberculosis_H37Rv        AAINLLPLLPFDGGHIAVAVFERIRNMVRSARGKVAAAPVNYLKLLPATY
MMAR_1837|M.marinum_M               GAINLLPLLPFDGGHIAVAVFEKIRNMIRAARGKVAAAPVNYLKLMPATY
MUL_2086|M.ulcerans_Agy99           GAINLLPLLPFDGGHIAVAVFEKIRNMIRAARGKVAAAPVNYLKLMPATY
MAB_3170c|M.abscessus_ATCC_199      GAINLLPLLPFDGGHIAVATYEKVRNMIRSARGLAVGAPVNYMKLMPATY
                                    ..:**:****:*****::* :*::** :* *** ....****:**:* **

Mflv_4082|M.gilvum_PYR-GCK          VVIIVMVGFTLLTVTADVVNPITLFQ
Mvan_2261|M.vanbaalenii_PYR-1       VVIIVMVGFTLLTVTADVINPITLFQ
TH_1400|M.thermoresistible__bu      VILVVVAGYMLLTVTADLVNPIRLFQ
MSMEG_2579|M.smegmatis_MC2_155      VVLAVVAGYMLLTVTADLVNPLSIFQ
MLBr_01582|M.leprae_Br4923          VVLVFVVGYVLLTVTADLVNPIRLFQ
MAV_3726|M.avium_104                VVLVFVVGYMLLTVTADLVNPIRLFQ
Mb2894c|M.bovis_AF2122/97           VVLVLVVGYMLLTVTADLVNPIRLFQ
Rv2869c|M.tuberculosis_H37Rv        VVLVLVVGYMLLTVTADLVNPIRLFQ
MMAR_1837|M.marinum_M               VVLVFVVGYMLLTVTADLVNPIRLFQ
MUL_2086|M.ulcerans_Agy99           VVLVFVVGYMLLTVTADLVNPIRLFQ
MAB_3170c|M.abscessus_ATCC_199      LVLVVVVGYMLLTITADIVNPIRLFQ
                                    ::: .:.*: ***:***::**: :**