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MFVIGIVLFALAILISVALHECGHMWVARATGMKVRRYFVGFGPTLWSTRRGETEYGLKAVPLGGFCDIA GMTSVEELAPDEADRAMFKQATWKRVAVLFAGPGANFVICLVLLYAIALIWGLPNLHPPTKAIVGETACV APEVAPGKLADCTGPGPAALAGIRPGDVIVKVGDTPVSTFDDMAAAIRKVHGNVPIVVDRDGTAITAYVD VTPTQRYLSGGSGPQGAPPQPSTVGAIGVGAVKVAPAHYGVFSAIPASVVFAGDLTVEVGKALVTIPTKV GALVHAIGGGQRDPQTPMSVVGASIIGGDTVDHGLWVAFWFFLAQLNLILGAINLVPLLPFDGGHIAIAV FEKVRNLIRSARGMVAAAPVNYLKLMPATYVVLVFVVGYMLLTVTADLVNPIRLFQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3726 | - | - | 100% (407) | peptidase M50 |
| M. avium 104 | MAV_1366 | - | 9e-05 | 33.75% (80) | trypsin |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2894c | - | 0.0 | 82.80% (407) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_4082 | - | 1e-159 | 66.27% (415) | peptidase M50 |
| M. tuberculosis H37Rv | Rv2869c | - | 0.0 | 82.56% (407) | transmembrane protein |
| M. leprae Br4923 | MLBr_01582 | - | 0.0 | 84.03% (407) | putative integral membrane protein |
| M. abscessus ATCC 19977 | MAB_3170c | - | 1e-135 | 58.91% (421) | protease/peptidase |
| M. marinum M | MMAR_1837 | - | 0.0 | 82.06% (407) | transmembrane protein |
| M. smegmatis MC2 155 | MSMEG_2579 | - | 1e-170 | 72.09% (412) | zinc metalloprotease |
| M. thermoresistible (build 8) | TH_1400 | - | 1e-173 | 72.53% (415) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_2086 | - | 0.0 | 81.57% (407) | transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_2261 | - | 1e-160 | 65.78% (415) | peptidase M50 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4082|M.gilvum_PYR-GCK -MMYVLGVTLFALAILVSVALHECGHMWVARATGMKVRRYFVGFGPTLWS
Mvan_2261|M.vanbaalenii_PYR-1 -MMYVLGVTLFALAILVSVALHECGHMWVARATGMKVRRYFVGFGPTLWS
TH_1400|M.thermoresistible__bu -MMFAIGVALFALAILVSVALHECGHMWVARATGMKVRRYFVGFGPTLWS
MSMEG_2579|M.smegmatis_MC2_155 -MMFGIGIVLFALAILVSVALHECGHMWVARATGMKVRRYFVGFGPTLWS
Mb2894c|M.bovis_AF2122/97 -MMFVTGIVLFALAILISVALHECGHMWVARRTGMKVRRYFVGFGPTLWS
Rv2869c|M.tuberculosis_H37Rv -MMFVTGIVLFALAILISVALHECGHMWVARRTGMKVRRYFVGFGPTLWS
MMAR_1837|M.marinum_M -MMFVVGIVLFALAILISVALHECGHMWVARATGMKVRRYFVGFGPTLWS
MUL_2086|M.ulcerans_Agy99 -MMFVVGIVLFALAILISVALHECGHMWVARATGMKVRRYFVGFGPTLWS
MAV_3726|M.avium_104 -MMFVIGIVLFALAILISVALHECGHMWVARATGMKVRRYFVGFGPTLWS
MLBr_01582|M.leprae_Br4923 -MMFALGIVLFAIAILISVALHECGHLWVACATGMKVRRYFVGFGPTLWS
MAB_3170c|M.abscessus_ATCC_199 MAAYAIGIALFALAILVSVALHECGHMWVAQATGMKVRRYFVGFGPTLWS
: *:.***:***:*********:*** ******************
Mflv_4082|M.gilvum_PYR-GCK TRRPNKL-------GETEYGIKAVPLGGFCDIAGMTAVEELDPADRPYAM
Mvan_2261|M.vanbaalenii_PYR-1 TWRPNKL-------GQTEYGVKAIPLGGFCDIAGMTAVEELDPEDRPYAM
TH_1400|M.thermoresistible__bu THRPNRL-------GSTEYGIKAVPLGGFCDIAGMTAIDELKPDEQPYAM
MSMEG_2579|M.smegmatis_MC2_155 TRRANRL-------GSTEYGIKAIPLGGFCDIAGMTSVDEIAPEDRPYAM
Mb2894c|M.bovis_AF2122/97 TRR-----------GETEYGVKAVPLGGFCDIAGMTPVEELDPDERDRAM
Rv2869c|M.tuberculosis_H37Rv TRR-----------GETEYGVKAVPLGGFCDIAGMTPVEELDPDERDRAM
MMAR_1837|M.marinum_M TRR-----------GETEYGVKAIPAGGFCDIAGMTPVEDLEPDEHDRAM
MUL_2086|M.ulcerans_Agy99 TRR-----------GETEYGVKAIPAGGFCDIAGMTPVEDLEPDEHDRAM
MAV_3726|M.avium_104 TRR-----------GETEYGLKAVPLGGFCDIAGMTSVEELAPDEADRAM
MLBr_01582|M.leprae_Br4923 TRR-----------GETQYGIKAVPLGGFCDIVGMTSVEKLEPDESDRAM
MAB_3170c|M.abscessus_ATCC_199 TKRKSNRPNKQGANDIVEYGVKAVPLGGFCDIAGMTSVEELTPEESDRAM
* * . .:**:**:* ******.***.::.: * : **
Mflv_4082|M.gilvum_PYR-GCK YRQKTWKRVAVLFAGPAMNFIIGLVLIYGIAIVWGLPNITAPTTAVVGET
Mvan_2261|M.vanbaalenii_PYR-1 YKQKTWKRVAVLFAGPAMNFVIGLVLIYAIALIWGLPNITAPTTAVVGET
TH_1400|M.thermoresistible__bu YRQKTWKRVAVLFAGPGMNFVIGLVLIYAIAVIWGLPTLNPPTTAVVGET
MSMEG_2579|M.smegmatis_MC2_155 YKQKVWKRVAVLFAGPAMNFVIGLVLIYGIAIVWGLPNLHQPTTAIVGET
Mb2894c|M.bovis_AF2122/97 YKQATWKRVAVLFAGPGMNLAICLVLIYAIALVWGLPNLHPPTRAVIGET
Rv2869c|M.tuberculosis_H37Rv YKQATWKRVAVLFAGPGMNLAICLVLIYAIALVWGLPNLHPPTRAVIGET
MMAR_1837|M.marinum_M YKQATWKRVAVLFAGPGMNFVICLVLIYGIAVVWGLPNLHPPTQAIIGET
MUL_2086|M.ulcerans_Agy99 YKQATWKRVAVLFAGPGMNFVICLVLIYGIAVVWGLPNLHPPTQAIIGET
MAV_3726|M.avium_104 FKQATWKRVAVLFAGPGANFVICLVLLYAIALIWGLPNLHPPTKAIVGET
MLBr_01582|M.leprae_Br4923 YKQATWKRVAVLFAGPAMNFVICLVLIYGIALVWGLPNLHMPTRAVIGET
MAB_3170c|M.abscessus_ATCC_199 YKQKVWKRVAVLFAGPAMNFLIGIVVFYGVVLFWGLPDNNAPTHPEITQT
::* .***********. *: * :*::*.:.:.**** ** . : :*
Mflv_4082|M.gilvum_PYR-GCK SCIKSEVTQG--ELGDCVANSPAAAAGIEAGDVIVRVGDTEVPTFDALVE
Mvan_2261|M.vanbaalenii_PYR-1 SCIKSEVSQG--ELGDCVANSPAAAAGIQAGDVIVKVGDTEVPTFDALVE
TH_1400|M.thermoresistible__bu SCVAAEVRQG--ELSECSGPGPAALAGIQPGDVIVKVGDAEVADFTEMAT
MSMEG_2579|M.smegmatis_MC2_155 GCVAPQITLE--EMGECTGPGPAALAGIQAGDEIVKVGDTEVKDFAGMAA
Mb2894c|M.bovis_AF2122/97 GCVAQEVSQG--KLEQCTGPGPAALAGIRSGDVVVKVGDTPVSSFDEMAA
Rv2869c|M.tuberculosis_H37Rv GCVAQEVSQG--KLEQCTGPGPAALAGIRSGDVVVKVGDTPVSSFDEMAA
MMAR_1837|M.marinum_M GCVAPETAQG--KLEQCTGPGPAALAGLRAGDVVVKVGDTAVSTFDEMAT
MUL_2086|M.ulcerans_Agy99 GCVAPETAQG--KLEQCTGPGPAALAGLRAGDVVVKVGDTAVSTFGEMAT
MAV_3726|M.avium_104 ACVAPEVAPG--KLADCTGPGPAALAGIRPGDVIVKVGDTPVSTFDDMAA
MLBr_01582|M.leprae_Br4923 ACVASELDQG--KLGNCTGPGPAALAGLRAGDVVVKIGDTTVSTFDDMAA
MAB_3170c|M.abscessus_ATCC_199 SCVAPQKSADPRDVVACTGEGPAALAGLRAGDQVLTAGGTSVSTSTDLVT
.*: : .: * . .*** **:..** :: *.: * :.
Mflv_4082|M.gilvum_PYR-GCK AVRQESGPTVLTVQRDENGQVREFTTTVDVTPSQRYVAGEDGGPA---VP
Mvan_2261|M.vanbaalenii_PYR-1 AVRRQNGPTTLTVQRDENGEPREFTTTVDVTPSQRYVAGENGGPA---VP
TH_1400|M.thermoresistible__bu AVRQHRGPTELTVQRTVDGVTTEFTTVVDVTPTQRFTAGEDGEP----VP
MSMEG_2579|M.smegmatis_MC2_155 AVRKLDGPTRIEFKRDG----RVMDTVVDVTPTQRFTSADASAP------
Mb2894c|M.bovis_AF2122/97 AVRKSHGSVPIVVERDG----TAIVTYVDIESTQRWIPNGQGGE---LQP
Rv2869c|M.tuberculosis_H37Rv AVRKSHGSVPIVVERDG----TAIVTYVDIESTQRWIPNGQGGE---LQP
MMAR_1837|M.marinum_M AIRKLHGSVPIVVERDG----TTVTANVVIESTRRWVPNEQGNQ---LEP
MUL_2086|M.ulcerans_Agy99 AIRKLHGSMPIVVERDG----TTVTANVVIESTRRWVPNEQGNQ---LEP
MAV_3726|M.avium_104 AIRKVHGNVPIVVDRDG----TAITAYVDVTPTQRYLSGGSGPQGAPPQP
MLBr_01582|M.leprae_Br4923 VVRKLHGTVPIVFERDG----TAITSYVDITPTQRYMSKGKGSQ---LEP
MAB_3170c|M.abscessus_ATCC_199 AIRGLRGPQVFEIVRDG----KPQSLMVNVTETQRWD--EKAGK-----L
.:* * : . * * : ::*: .
Mflv_4082|M.gilvum_PYR-GCK VDVGSIGVTAAQFG-PTQYNAFTAVPGTFVFTKDLAVELGKAVVKIPTKI
Mvan_2261|M.vanbaalenii_PYR-1 VDVGSIGVTAAQFG-PTQYNPLTAVPGTFVFTKDLAVALGKAIVKIPTKI
TH_1400|M.thermoresistible__bu AEVGAIGVTAAQFG-PTQYNVLSAVPATFTFTGELAVELGKALAKIPTKV
MSMEG_2579|M.smegmatis_MC2_155 STVGAIGVSAVPVQPPAQYNPITAVPATFAFTGDLAVELGKSLAKIPTKI
Mb2894c|M.bovis_AF2122/97 ATVGAIGVGAARVG-PVRYGVFSAMPATFAFTGDLTVEVGKALAALPTKV
Rv2869c|M.tuberculosis_H37Rv ATVGAIGVGAARVG-PVRYGVFSAMPATFAVTGDLTVEVGKALAALPTKV
MMAR_1837|M.marinum_M ATVGAIGVGAAQSG-PTQYGILSALPATFAFTGDLTVEVGRALVAIPTKV
MUL_2086|M.ulcerans_Agy99 ATVGAIGVGAAQSG-PTQYGILSALPATFAFTGDLTVEVGRALVAIPTKV
MAV_3726|M.avium_104 STVGAIGVGAVKVA-PAHYGVFSAIPASVVFAGDLTVEVGKALVTIPTKV
MLBr_01582|M.leprae_Br4923 ATVGAIGVGAHHLL-PTHYGVFSALPATAAFAGDLTVEVGKALVTIPTKL
MAB_3170c|M.abscessus_ATCC_199 VPVGAVGASLSTYVPQKHYNPVTAIPATGNLIGTVAVETVKAIGKIPMKV
**::*. :*. .:*:*.: . ::* ::: :* *:
Mflv_4082|M.gilvum_PYR-GCK GALVDSISGGERDPETPISVVGASRIGGETVEAGIWVAFWFFLAQLNFVL
Mvan_2261|M.vanbaalenii_PYR-1 GALVHSITGGERDPETPISVVGASRIGGETVEHGIWVAFWFFLAQLNFVL
TH_1400|M.thermoresistible__bu GALVASITGDERDPETPISVVGASIIGGDTVNHGLWVAFWFFLAQLNFVL
MSMEG_2579|M.smegmatis_MC2_155 GALVEAIGGGERDKETPISVVGASIIGGETVDAGLWVAFWFFLAQLNFVL
Mb2894c|M.bovis_AF2122/97 GALVRAIGGGQRDPQTPISVVGASIIGGDTVDHGLWVAFWFFLAQLNLIL
Rv2869c|M.tuberculosis_H37Rv GALVRAIGGGQRDPQTPISVVGASIIGGDTVDHGLWVAFWFFLAQLNLIL
MMAR_1837|M.marinum_M GALVHAIGGGQRDPQTPISVVGASIIGGDTVDHGLWVAFWFFLAQLNLIL
MUL_2086|M.ulcerans_Agy99 GALVHAIGGGQRDPQTPISVVGASIIGGDTVDHGLWVAFWFFLAQLNLIL
MAV_3726|M.avium_104 GALVHAIGGGQRDPQTPMSVVGASIIGGDTVDHGLWVAFWFFLAQLNLIL
MLBr_01582|M.leprae_Br4923 GALVHAIGGGQRDPQTPMSVVGASIIGGDTVDHGLWVAFWFFLAQLNLIL
MAB_3170c|M.abscessus_ATCC_199 GALWDSITGSERAMDTPMSIVGASRMGGETVEHDMWIMFWILLAQLNFAL
*** :* *.:* :**:*:**** :**:**: .:*: **::*****: *
Mflv_4082|M.gilvum_PYR-GCK GGINLVPLLPLDGGHISIALYEKVRNKIREARGKVAAAPVNYLKLMPLTY
Mvan_2261|M.vanbaalenii_PYR-1 GAVNLIPLLPLDGGHISIALYEKLRNKLREARGKVAAGPVNYLKLMPVTY
TH_1400|M.thermoresistible__bu GAINLVPLLPFDGGHIAIATYEKIRNMIRSARGLTAAAPVNYLKLMPATY
MSMEG_2579|M.smegmatis_MC2_155 GAINLVPLLPFDGGHIAVATYEKIRNMIRSARGMVAAGPVNYLKLMPATY
Mb2894c|M.bovis_AF2122/97 AAINLLPLLPFDGGHIAVAVFERIRNMVRSARGKVAAAPVNYLKLLPATY
Rv2869c|M.tuberculosis_H37Rv AAINLLPLLPFDGGHIAVAVFERIRNMVRSARGKVAAAPVNYLKLLPATY
MMAR_1837|M.marinum_M GAINLLPLLPFDGGHIAVAVFEKIRNMIRAARGKVAAAPVNYLKLMPATY
MUL_2086|M.ulcerans_Agy99 GAINLLPLLPFDGGHIAVAVFEKIRNMIRAARGKVAAAPVNYLKLMPATY
MAV_3726|M.avium_104 GAINLVPLLPFDGGHIAIAVFEKVRNLIRSARGMVAAAPVNYLKLMPATY
MLBr_01582|M.leprae_Br4923 GAINLVPLLPFDGGHIAIAVFERIRNLIRSARGVVVAAPVNYLKLMPATY
MAB_3170c|M.abscessus_ATCC_199 GAINLLPLLPFDGGHIAVATYEKVRNMIRSARGLAVGAPVNYMKLMPATY
..:**:****:*****::* :*::** :* *** ....****:**:* **
Mflv_4082|M.gilvum_PYR-GCK VVIIVMVGFTLLTVTADVVNPITLFQ
Mvan_2261|M.vanbaalenii_PYR-1 VVIIVMVGFTLLTVTADVINPITLFQ
TH_1400|M.thermoresistible__bu VILVVVAGYMLLTVTADLVNPIRLFQ
MSMEG_2579|M.smegmatis_MC2_155 VVLAVVAGYMLLTVTADLVNPLSIFQ
Mb2894c|M.bovis_AF2122/97 VVLVLVVGYMLLTVTADLVNPIRLFQ
Rv2869c|M.tuberculosis_H37Rv VVLVLVVGYMLLTVTADLVNPIRLFQ
MMAR_1837|M.marinum_M VVLVFVVGYMLLTVTADLVNPIRLFQ
MUL_2086|M.ulcerans_Agy99 VVLVFVVGYMLLTVTADLVNPIRLFQ
MAV_3726|M.avium_104 VVLVFVVGYMLLTVTADLVNPIRLFQ
MLBr_01582|M.leprae_Br4923 VVLVFVVGYVLLTVTADLVNPIRLFQ
MAB_3170c|M.abscessus_ATCC_199 LVLVVVVGYMLLTITADIVNPIRLFQ
::: .:.*: ***:***::**: :**