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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_1337 | - | - | 100% (617) | cyclododecanone monooxygenase |
| M. thermoresistible (build 8) | TH_4536 | - | 6e-63 | 32.92% (486) | PUTATIVE steroid monooxygenase |
| M. thermoresistible (build 8) | TH_4012 | - | 5e-56 | 31.49% (505) | PUTATIVE putative FAD dependent oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1428c | - | 2e-58 | 30.93% (514) | monoxygenase |
| M. gilvum PYR-GCK | Mflv_1789 | - | 0.0 | 70.98% (610) | cyclohexanone monooxygenase |
| M. tuberculosis H37Rv | Rv1393c | - | 2e-58 | 30.93% (514) | monoxygenase |
| M. leprae Br4923 | MLBr_00065 | - | 1e-17 | 29.52% (227) | putative monooxygenase |
| M. abscessus ATCC 19977 | MAB_4024c | - | 1e-63 | 32.50% (523) | monooxygenase |
| M. marinum M | MMAR_0309 | - | 0.0 | 80.98% (610) | monoxygenase |
| M. avium 104 | MAV_5206 | - | 0.0 | 85.86% (608) | cyclododecanone monooxygenase |
| M. smegmatis MC2 155 | MSMEG_5625 | - | 0.0 | 83.66% (606) | cyclododecanone monooxygenase |
| M. ulcerans Agy99 | MUL_4813 | - | 0.0 | 80.63% (537) | monoxygenase |
| M. vanbaalenii PYR-1 | Mvan_4961 | - | 0.0 | 72.25% (609) | FAD dependent oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1428c|M.bovis_AF2122/97 --------------------------------------------------
Rv1393c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_4024c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1337|M.thermoresistible__bu ----MTLFGDGCGPTQTPDDIDIEALREKYRIEREKRLRPEGSKQYIELT
MAV_5206|M.avium_104 MTPDVDTQQDGCGPTQTPDDIDIDALRQKYAHEREKRLRKEGSKQYIELE
MSMEG_5625|M.smegmatis_MC2_155 ------MSQTTCGPTDTPTDIDIDALREKYRVEREKRLRAEGSKQYVETR
MMAR_0309|M.marinum_M ---MTEMTAPDCPPSQTPGDIDLPALREKYRHEREKRLRPEGSRQYIELV
MUL_4813|M.ulcerans_Agy99 ---MTEMTAPDCPPSQTPGDIDLPAVREKYRQEREKRLRPEGSRQYIELV
Mflv_1789|M.gilvum_PYR-GCK --------MNECGPTDTPDDIDIPALRERYAAERAKRLRPEGADQYLELE
Mvan_4961|M.vanbaalenii_PYR-1 -------METPCGPTDTPTDIDIPALREKYAQERAKRLRPEGGSQYLELE
MLBr_00065|M.leprae_Br4923 --------------------------------------------------
Mb1428c|M.bovis_AF2122/97 --------------------MMPDYHALIVGAGFSGIGAAIKLD-RAGFS
Rv1393c|M.tuberculosis_H37Rv --------------------MMPDYHALIVGAGFSGIGAAIKLD-RAGFS
MAB_4024c|M.abscessus_ATCC_199 -------MSPAARHATTAELEQPDHEVAVIGAGFGGIGTGISLQ-RKGIH
TH_1337|M.thermoresistible__bu DDFAGYYETDPYTPVAERDPIHEDIDVAVLGGGFGGLLSAVHLK-KAGVD
MAV_5206|M.avium_104 DDFSGYYEVDPYTPVTPREPIREDIDVAVLGGGFAGLLSAAHLK-KAGVD
MSMEG_5625|M.smegmatis_MC2_155 DQFAQFGEVDPHTPYVERDSLDIDIDVAVLGGGFAGLLVGASLK-KAGVE
MMAR_0309|M.marinum_M DDFAGYYETDPYSPPLQRDPISADIDVLVLGGGFGGLLCGAHLK-KAGVA
MUL_4813|M.ulcerans_Agy99 DDFAGYYESDPYSPPLQRDPISADIDVLVLGGGFGGLLCAAHLK-KAGVA
Mflv_1789|M.gilvum_PYR-GCK GDFAEFAEVDPYTTATPRDPIVEDTDVVILGGGFAGLLAGAYLK-KAGVT
Mvan_4961|M.vanbaalenii_PYR-1 GDFAEFYEVDPYTTVTERDPIAEDVDVVILGGGFAGLLAGAYLK-KAGVE
MLBr_00065|M.leprae_Br4923 ---------------MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNK
.. ::*.*:.*: . *. :
Mb1428c|M.bovis_AF2122/97 DYLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWS-RTYAPG
Rv1393c|M.tuberculosis_H37Rv DYLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWS-RTYAPG
MAB_4024c|M.abscessus_ATCC_199 DFIILDKWDQVGGTWHANTYPGVAVDIPSVVYSFSYEQRGDWS-RLFAPG
TH_1337|M.thermoresistible__bu DVRIIELGGDFGGVWYWNRYPGIQCDNESYCYIPLLEELDFMPSKKFADG
MAV_5206|M.avium_104 DVRIIELGGDFGGVWYWNRYPGIQCDNESYCYIPLLEELDFMPSKKFADG
MSMEG_5625|M.smegmatis_MC2_155 DVHIIEMGGDFGGVWYWNRYPGIQCDNESYCYIPLLEELGFMPSKKFADG
MMAR_0309|M.marinum_M DVRIIELGGDFGGVWYWNRYPGLQCDNESYCYIPLLEELNYMPSKKFADG
MUL_4813|M.ulcerans_Agy99 DVRIIELGGDFGGVWYWNRYPGLQCDNESYCYIPLLEELNYMPSKKFADG
Mflv_1789|M.gilvum_PYR-GCK GIRVIEMAGDFGGVWYWNRFPGIQCDNDAYCYIPLLEELGFMPSKKFADG
Mvan_4961|M.vanbaalenii_PYR-1 GIRVIEMAGDFGGVWYWNRFPGIQCDNDAYCYIPMLEELGFIPSKKFADG
MLBr_00065|M.leprae_Br4923 SYVILEKRAGMGGTWDLFRYPGIRSDSD--MYTLGFRFRPWTKCQAIADG
. ::: .**.* :**: * * . : * *
Mb1428c|M.bovis_AF2122/97 HELKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGGE---
Rv1393c|M.tuberculosis_H37Rv HELKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGGE---
MAB_4024c|M.abscessus_ATCC_199 IELQQYAESMVHKYGLRDKLRLGTSITRAEFDERNSLWRLATDGGKE---
TH_1337|M.thermoresistible__bu PEIYQHCRNIGKHFGLYDKAIFSTQVRSMRWDDEISRWRIGTNRGDD---
MAV_5206|M.avium_104 AEIYQHCRNIGKHFGLYDSAIFSTQVHDLRWDEQIKRWRVSTNRGDD---
MSMEG_5625|M.smegmatis_MC2_155 AEIFQHCRNIGKHFGLYDGAIFSTQVRDMRWEDDLKRWRISTNRGDD---
MMAR_0309|M.marinum_M SEIYEHCRRIGKHYGLYDSAIFGTQVRELHWDEAIRRWRVGTNRGDD---
MUL_4813|M.ulcerans_Agy99 SEIYEHCRRIGKHYGLYDSAIFGTQVRELHWDEAIRRWRVGTNRGDD---
Mflv_1789|M.gilvum_PYR-GCK AEIFGHCRNIGKHFGLYDGALFSTQVRELRWDDGTQRWQISTDRGDD---
Mvan_4961|M.vanbaalenii_PYR-1 AEILQHCRNIGKHFGLYDGALFSTQVRELQWDDDLRRWRISTDRGDD---
MLBr_00065|M.leprae_Br4923 KPILEYIKSTAVMHGIDKYIRLNHKVTGADWSSIENRWTVQVENNGTPRM
: : . .*: . :. .: :.. * : .: .
Mb1428c|M.bovis_AF2122/97 ITARFLISACGILTVPK--LPDIDGVDSFE---GVTMHTARWDHTQD---
Rv1393c|M.tuberculosis_H37Rv ITARFLISACGILTVPK--LPDIDGVDSFE---GVTMHTARWDHTQD---
MAB_4024c|M.abscessus_ATCC_199 ITARYCVMAVGGLERPK--MPDIPGVHDFG---GTLMHTALWDHDVA---
TH_1337|M.thermoresistible__bu IRARFVVMASGPFHRPK--LPGIPGIKDFQ---GHSFHSSRWDYDYTGGD
MAV_5206|M.avium_104 IRARFVVLASGPFHRPK--LPGIPGIKTFG---GHSFHSSRWDYDYTGGD
MSMEG_5625|M.smegmatis_MC2_155 IRARFVVMASGSFNRPK--LPGIPGIKDFG---GHIFHSSRWDYSYTGGD
MMAR_0309|M.marinum_M IRARFVVMASGPFHRPK--LPGIPGIKDFR---GHSFHSARWDYEYTGGD
MUL_4813|M.ulcerans_Agy99 IRARFVVMASGPFHRPK--LPGIPGIKDFR---GHSFHPARWDYEYTGGD
Mflv_1789|M.gilvum_PYR-GCK IRARFVVMAQGSYNRPK--LPGIPGIKDFRDAGGHVFHSARWDYDYTGGD
Mvan_4961|M.vanbaalenii_PYR-1 IRARFVVMAQGSYNRPK--LPGIPGIKDF---AGHVFHSARWDYDYTGGD
MLBr_00065|M.leprae_Br4923 ISCSFLFLCSGYYNYEQGYAPTFLGSEDFT---GPIIHPQHWPEDLD---
* . : . . * : * : * . * * :*. *
Mb1428c|M.bovis_AF2122/97 -------LTGKRVGIIGTGASAVQVIPEMAPI-VSHLTVFQRTPIWCFPK
Rv1393c|M.tuberculosis_H37Rv -------LTGKRVGIIGTGASAVQVIPEMAPI-VSHLTVFQRTPIWCFPK
MAB_4024c|M.abscessus_ATCC_199 -------LAGKRVAVIGTGATSLQLVPAIVDE-TSHLTVFQRTPIWVGPK
TH_1337|M.thermoresistible__bu TNGNLHKLADKRVAVIGTGATAIQIVPHLARD-SKHLYVFQRTPSTVDER
MAV_5206|M.avium_104 SGGNLHKLADKRVGVVGTGATGIQIVPFLARY-AQHLYVFQRTPSTVDAR
MSMEG_5625|M.smegmatis_MC2_155 TTGNLHKLHDKKVALIGTGATGVQLVPYLGRD-AQHLYVFQRTPSTVDER
MMAR_0309|M.marinum_M STGGLTGLADKRVAVVGTGATAVQIVPFLGRY-AKHLYVFQRTPSSVGER
MUL_4813|M.ulcerans_Agy99 STGGLTGLADKRVAVVGTGATAVQIVPFLGRY-AKHLYVFQRTPSSVGER
Mflv_1789|M.gilvum_PYR-GCK ADGGLHKLADKRVALVGTGATGIQLVPHLGRD-AEHLFVFQRTPSSVDQR
Mvan_4961|M.vanbaalenii_PYR-1 ADGGLHKLADKRVALVGTGATGVQLVPHLGRD-AKQLFVFQRTPSSVDER
MLBr_00065|M.leprae_Br4923 -------YAAKNIVVIGSGATAVTLVPALANSGAKHVTMLQRSPTYIVSQ
*.: ::*:**:.: ::* : .:: ::**:* :
Mb1428c|M.bovis_AF2122/97 FDVPLPTAVRWAMRIPGGKAVHR---------------------------
Rv1393c|M.tuberculosis_H37Rv FDVPLPTAVRWAMRIPGGKAVHR---------------------------
MAB_4024c|M.abscessus_ATCC_199 FDLEIGPLGRIILGNSRIRSAIR---------------------------
TH_1337|M.thermoresistible__bu NNAPTDPEWVKTLKPGWQKERQRNFHAWT-FEGMALGQPDLVCDFWTELG
MAV_5206|M.avium_104 NNTPTDPEWVKTLRPGWQRERQRNFHAWT-FEGMAPGQPDLVCDFWTELG
MSMEG_5625|M.smegmatis_MC2_155 NNTPTDPEWVKTLQPGWQKERQRNFHAWT-FEGMALGQPDLVCDFWTELG
MMAR_0309|M.marinum_M NNTPTDPEWAKSLQPGWQKQRQRNFHSWT-FEGMALGQPDYVCDFWTELG
MUL_4813|M.ulcerans_Agy99 NNTPTDPEWAKSLQPGWQKQRQRNFHSWT-FEGMALGQPDYVCDFWTELG
Mflv_1789|M.gilvum_PYR-GCK VNTPTDPDWAASLQPGWQEERKRNFHNWSPFVGVVFGEPDLVCDFWTELG
Mvan_4961|M.vanbaalenii_PYR-1 VNTPTDPAWAASLRPGWQEERKRNFHNWSPFVGVVFGEPDLVCDFWTELG
MLBr_00065|M.leprae_Br4923 PAKDKIAARLNRWLPDKYA-------------------------------
.
Mb1428c|M.bovis_AF2122/97 -LLSQAFVEATFP--IAAHYFAVFPLAKHMESAG--RRYLRQQVHDPVVR
Rv1393c|M.tuberculosis_H37Rv -LLSQAFVEATFP--IAAHYFAVFPLAKHMESAG--RRYLRQQVHDPVVR
MAB_4024c|M.abscessus_ATCC_199 -AIATVGIEMAMSGQVAGPAWLINAVRRAGEAPM--RRWMRSQVDDPVIR
TH_1337|M.thermoresistible__bu RNTAARVMALDDPASLTPEQFMAIREEEDFKLMERLRRRIDAIVEDPETA
MAV_5206|M.avium_104 RNTAARVLALDDPASLTPEQFMAIREEEDYKIMERLRRRIDTLIDDPATA
MSMEG_5625|M.smegmatis_MC2_155 RNTAARVMALEDPASMTPEQFMAIREEEDYKVMERLRRRVDQLVKDPQTA
MMAR_0309|M.marinum_M RNTAARVLALEDPAALSPEQFMAIREEEDYKVMERLRRRIQSIVDDTSTA
MUL_4813|M.ulcerans_Agy99 RNTAARVLALEDPAALSPEQFMAIREEEDYKVMERLRRRIQSIVDDTSTA
Mflv_1789|M.gilvum_PYR-GCK RNLTARIAGSPDPTAVTIEQIMAFREEEDYKIMERLRRRVAEIVQDPETA
Mvan_4961|M.vanbaalenii_PYR-1 RNLTARIAASPDPAAVTIEQIMAFREEEDYKIMERLRRRVAAVVEDPATA
MLBr_00065|M.leprae_Br4923 -YTAVRWKNILRQSALYGACQKWPQRMRNILLGHVARRLPKGYDVQKHFG
: : . ** :
Mb1428c|M.bovis_AF2122/97 EQLTPRYAVGCKRPGFHNTYLSTFNRDNVRLVTEPIDKITPTAVAT---T
Rv1393c|M.tuberculosis_H37Rv EQLTPRYAVGCKRPGFHNTYLSTFNRDNVRLVTEPIDKITPTAVAT---T
MAB_4024c|M.abscessus_ATCC_199 EKLIPRYGLGCKRPSMSNEYLKTFNRDDVSLITESIECVTPDGVRT---V
TH_1337|M.thermoresistible__bu EKLKPYYRFLCKRPLSNDEYLPSFNRPNVTLVDVSESKGVERITPKGLVA
MAV_5206|M.avium_104 EALKPYYRFLCKRPCSNDDYLPSFNRPNVTLVDVSASKGVERATEKGLVA
MSMEG_5625|M.smegmatis_MC2_155 EALKPYYRFLCKRPCSNDEYLSTFNRPNVTLVDVSETKGVERITQTGIVA
MMAR_0309|M.marinum_M EALKPYYRFLCKRPCTNDDYLQTFNRPNVTLVDVSQTRGVQRATETGLVA
MUL_4813|M.ulcerans_Agy99 EALKPYYRFLCKRPCTNDDYLQTFNRPNVTLVDVSQTRGVQRATETGLVA
Mflv_1789|M.gilvum_PYR-GCK EALKPYYRFMCKRPCSSEQYLDTFNRPNVTLVDVSESKGVERLTEKGIVA
Mvan_4961|M.vanbaalenii_PYR-1 EALKPYYRFMCKRPCSSEQYLATFNRPNVTLVDVSESKGVERLTEKGIVA
MLBr_00065|M.leprae_Br4923 PHYNPWEQRLCLVP--DGDLFRAIRKGTVDMVTDAIDRFTSTGIRLK---
* * * : ::.: * :: . .
Mb1428c|M.bovis_AF2122/97 DGASHEIDVLVLATGFKVLDTDS--IPTYAVTGTGGASLSRFWDEHRLQA
Rv1393c|M.tuberculosis_H37Rv DGASHEIDVLVLATGFKVLDTDS--IPTYAVTGTGGASLSRFWDEHRLQA
MAB_4024c|M.abscessus_ATCC_199 DGVEHVVDVLICATGFRLWDKGS--VPPFPVHGRGGQDLGEFWDRHRFQS
TH_1337|M.thermoresistible__bu GGIEYEVDCIIYASGFEITTDIKRRYSIDVIEGRGGVSLYDHWRDG-YKT
MAV_5206|M.avium_104 NGVEYELDCIIYASGFEITTEISRRYSIETIAGRDGLSLFDYWRDG-YKT
MSMEG_5625|M.smegmatis_MC2_155 NGNEYEVDCIIFASGFEITTEIRRRFSIDSIKGRDGVSLYDHWADG-YKT
MMAR_0309|M.marinum_M NDTEYELDCIIYASGFEITTQISRRYSIDEIRGRDNVSLFDYWRNG-YQT
MUL_4813|M.ulcerans_Agy99 NDTEYELDCIIYASGFEITTQISHRYSIDEIRGRDNVSLFDYWRNG-YQT
Mflv_1789|M.gilvum_PYR-GCK NGVEYEVDCVIFASGFEISTEIHRRYAIDSVVGRDGVSLFDYWRDD-YKT
Mvan_4961|M.vanbaalenii_PYR-1 NGVEYEVDCVIFASGFEISTEISRRYAIDRIVGRDGLSLFEHWRDD-YKT
MLBr_00065|M.leprae_Br4923 SGNELRADIIVTATGLNLQLFGG---AVATVDGQP-------VDLAQTMS
.. . * :: *:*:.: . : * :
Mb1428c|M.bovis_AF2122/97 YEGVSVPGYPNFFTVFGPYGYVGSSYFALIETQAHHIIRCLKRARRTGAT
Rv1393c|M.tuberculosis_H37Rv YEGVSVPGYPNFFTVFGPYGYVGSSYFALIETQAHHIIRCLKRARRTGAT
MAB_4024c|M.abscessus_ATCC_199 YQGVSVPGYPNMFSITGPYGFVLGSYLWMIEATSAHLARAIAETKRRGAT
TH_1337|M.thermoresistible__bu FHGMTSRGFPNQFFTGFTQVGISANISANYELQGEHIAYIIAEALNRGAT
MAV_5206|M.avium_104 LHGMTSRGFPNQFYTGFTQVGISANIAANYELQGEHIAYIIAEALKRGAA
MSMEG_5625|M.smegmatis_MC2_155 LHGMASRGFPNQFFTGFTQVGISANISANYELQGEHIAYVIAEALNRGVT
MMAR_0309|M.marinum_M LHGMTSRGFPNQFFTGFTQVGISANIAANYELQGEHIAYIIAEALARGAT
MUL_4813|M.ulcerans_Agy99 LHGMTSRGFPNQFFTGFTQVGISANIAANYELQGEHIAYIIAEALARGAT
Mflv_1789|M.gilvum_PYR-GCK LHGMTSRGFPNQFFMGFIQGGVSANTTAMFEQQAEHIAYIIAEAQNRGAA
Mvan_4961|M.vanbaalenii_PYR-1 LHGMTSRGFPNQFFMGFIQGGVSANTTAMFEQQAEHIAYIIAEAQNRGAT
MLBr_00065|M.leprae_Br4923 YKGMMLSGLPNMIYT---VGYTNASWTLKADLVSEFFCRLLNYMNANDFD
.*: * ** : .. : . .: : .
Mb1428c|M.bovis_AF2122/97 RIEVTEEANARYFAEVMRRRHRQVFWQDSCRLANSYYFDKNGDVPLRPTT
Rv1393c|M.tuberculosis_H37Rv RIEVTEEANARYFAEVMRRRHRQVFWQDSCRLANSYYFDKNGDVPLRPTT
MAB_4024c|M.abscessus_ATCC_199 VCEIRQEAHDEYFRKCLKRQEKNFLFTDVCAGSNTYYLDQNGDSPFRPTT
TH_1337|M.thermoresistible__bu VVEPTQDAQDGWCRTIRETAVDNSAFDASCTPG---YYNNEGGGGG----
MAV_5206|M.avium_104 TVEPSDEAQQQWCTTIRETAVDNSAFDAQCTPG---YYNNEGGGGG----
MSMEG_5625|M.smegmatis_MC2_155 TVEPSQQAQDAWCRTIKENFVDNSAFDAECTPG---YYNNEGGGGG----
MMAR_0309|M.marinum_M VVEPSQQAQDQWCRTIRETAIDNTQFDLECTPG---YYNNEGGGPGAAEG
MUL_4813|M.ulcerans_Agy99 VVEPSQQAQD----------------------------------------
Mflv_1789|M.gilvum_PYR-GCK VVEPAQEAQDNWVHTVRELAIDNSAFEMSCTPG---YYNNEGRGGA----
Mvan_4961|M.vanbaalenii_PYR-1 TVEPSQEGQDNWVSTVRELAIDNSAFELSCTPG---YYNNEGRGGK----
MLBr_00065|M.leprae_Br4923 TVAVEYPGSDVEERPFMDFTPGYVLRSLDALPK------QGSRTPWR--L
.
Mb1428c|M.bovis_AF2122/97 TVEAYWRSRRFDLGDYRISS-------------------
Rv1393c|M.tuberculosis_H37Rv TVEAYWRSRRFDLGDYRISS-------------------
MAB_4024c|M.abscessus_ATCC_199 HGEMYWQNRHYNLDVYRYSTASVVPETVASTAGESV---
TH_1337|M.thermoresistible__bu EGIRSHLGEPYGPGFYAFGDLLAEWRSKGDLDGLELRGA
MAV_5206|M.avium_104 EGIRSHLGEPYGPGFYAFEDLLRAWRDKGDLEGLVLGS-
MSMEG_5625|M.smegmatis_MC2_155 EGIRSHLGEPYGPGFYAFGDLLKQWRDKGDLDGLEIS--
MMAR_0309|M.marinum_M EGIRSHIGEPYGPGFYAFGDLLAQWRSKGDLTGLILES-
MUL_4813|M.ulcerans_Agy99 ---------------------------------------
Mflv_1789|M.gilvum_PYR-GCK VRNGAFLGDFYSPGFYAFDELIAAWRDSGDLEGLELS--
Mvan_4961|M.vanbaalenii_PYR-1 EGNGAFLGDFYSPGFYAFDELIAEWRARGALEGLELRG-
MLBr_00065|M.leprae_Br4923 NQNYLRDIRLIRRGKVADEGLLFAKKTTPVTV-------