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M. avium 104 MAV_5206 (-)

annotation: cyclododecanone monooxygenase
coordinates: 5355974 - 5357833
length: 619

TPDVDTQQDGCGPTQTPDDIDIDALRQKYAHEREKRLRKEGSKQYIELEDDFSGYYEVDPYTPVTPREPI
REDIDVAVLGGGFAGLLSAAHLKKAGVDDVRIIELGGDFGGVWYWNRYPGIQCDNESYCYIPLLEELDFM
PSKKFADGAEIYQHCRNIGKHFGLYDSAIFSTQVHDLRWDEQIKRWRVSTNRGDDIRARFVVLASGPFHR
PKLPGIPGIKTFGGHSFHSSRWDYDYTGGDSGGNLHKLADKRVGVVGTGATGIQIVPFLARYAQHLYVFQ
RTPSTVDARNNTPTDPEWVKTLRPGWQRERQRNFHAWTFEGMAPGQPDLVCDFWTELGRNTAARVLALDD
PASLTPEQFMAIREEEDYKIMERLRRRIDTLIDDPATAEALKPYYRFLCKRPCSNDDYLPSFNRPNVTLV
DVSASKGVERATEKGLVANGVEYELDCIIYASGFEITTEISRRYSIETIAGRDGLSLFDYWRDGYKTLHG
MTSRGFPNQFYTGFTQVGISANIAANYELQGEHIAYIIAEALKRGAATVEPSDEAQQQWCTTIRETAVDN
SAFDAQCTPGYYNNEGGGGGEGIRSHLGEPYGPGFYAFEDLLRAWRDKGDLEGLVLGS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_5206--100% (619)cyclododecanone monooxygenase
M. avium 104MAV_3018-1e-5832.86% (493) steroid monooxygenase
M. avium 104MAV_1604-7e-5532.20% (500) steroid monooxygenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1428c-5e-5330.02% (483) monoxygenase
M. gilvum PYR-GCKMflv_1789-0.071.80% (610) cyclohexanone monooxygenase
M. tuberculosis H37RvRv1393c-5e-5330.02% (483) monoxygenase
M. leprae Br4923MLBr_00065-8e-1629.07% (227) putative monooxygenase
M. abscessus ATCC 19977MAB_0074c-4e-6032.39% (497) putative (cyclohexanone) monooxygenase
M. marinum MMMAR_0309-0.080.88% (612) monoxygenase
M. smegmatis MC2 155MSMEG_5625-0.081.38% (607) cyclododecanone monooxygenase
M. thermoresistible (build 8)TH_1337-0.085.86% (608) cyclododecanone monooxygenase
M. ulcerans Agy99MUL_4813-0.081.34% (536) monoxygenase
M. vanbaalenii PYR-1Mvan_4961-0.072.32% (607) FAD dependent oxidoreductase

CLUSTAL 2.0.9 multiple sequence alignment


Mb1428c|M.bovis_AF2122/97           --------------------------------------------------
Rv1393c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_5206|M.avium_104                MTPDVDTQQDGCGPTQTPDDIDIDALRQKYAHEREKRLRKEGSKQYIELE
TH_1337|M.thermoresistible__bu      ----MTLFGDGCGPTQTPDDIDIEALREKYRIEREKRLRPEGSKQYIELT
MMAR_0309|M.marinum_M               ---MTEMTAPDCPPSQTPGDIDLPALREKYRHEREKRLRPEGSRQYIELV
MUL_4813|M.ulcerans_Agy99           ---MTEMTAPDCPPSQTPGDIDLPAVREKYRQEREKRLRPEGSRQYIELV
MSMEG_5625|M.smegmatis_MC2_155      ------MSQTTCGPTDTPTDIDIDALREKYRVEREKRLRAEGSKQYVETR
Mflv_1789|M.gilvum_PYR-GCK          --------MNECGPTDTPDDIDIPALRERYAAERAKRLRPEGADQYLELE
Mvan_4961|M.vanbaalenii_PYR-1       -------METPCGPTDTPTDIDIPALREKYAQERAKRLRPEGGSQYLELE
MAB_0074c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_00065|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1428c|M.bovis_AF2122/97           --------------------MMPDYHALIVGAGFSGIGAAIKLDR-AGFS
Rv1393c|M.tuberculosis_H37Rv        --------------------MMPDYHALIVGAGFSGIGAAIKLDR-AGFS
MAV_5206|M.avium_104                DDFSGYYEVDPYTPVTPREPIREDIDVAVLGGGFAGLLSAAHLKK-AGVD
TH_1337|M.thermoresistible__bu      DDFAGYYETDPYTPVAERDPIHEDIDVAVLGGGFGGLLSAVHLKK-AGVD
MMAR_0309|M.marinum_M               DDFAGYYETDPYSPPLQRDPISADIDVLVLGGGFGGLLCGAHLKK-AGVA
MUL_4813|M.ulcerans_Agy99           DDFAGYYESDPYSPPLQRDPISADIDVLVLGGGFGGLLCAAHLKK-AGVA
MSMEG_5625|M.smegmatis_MC2_155      DQFAQFGEVDPHTPYVERDSLDIDIDVAVLGGGFAGLLVGASLKK-AGVE
Mflv_1789|M.gilvum_PYR-GCK          GDFAEFAEVDPYTTATPRDPIVEDTDVVILGGGFAGLLAGAYLKK-AGVT
Mvan_4961|M.vanbaalenii_PYR-1       GDFAEFYEVDPYTTVTERDPIAEDVDVVILGGGFAGLLAGAYLKK-AGVE
MAB_0074c|M.abscessus_ATCC_199      -----------------MKALVKNVDVVVVGAGFAGLYALQRLRS-QGLS
MLBr_00065|M.leprae_Br4923          ---------------MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNK
                                                             .. ::*.*:.*:     *       

Mb1428c|M.bovis_AF2122/97           DYLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFE---QSRHWS-RTY
Rv1393c|M.tuberculosis_H37Rv        DYLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFE---QSRHWS-RTY
MAV_5206|M.avium_104                DVRIIELGGDFGGVWYWNRYPGIQCDNESYCYIPLLE---ELDFMPSKKF
TH_1337|M.thermoresistible__bu      DVRIIELGGDFGGVWYWNRYPGIQCDNESYCYIPLLE---ELDFMPSKKF
MMAR_0309|M.marinum_M               DVRIIELGGDFGGVWYWNRYPGLQCDNESYCYIPLLE---ELNYMPSKKF
MUL_4813|M.ulcerans_Agy99           DVRIIELGGDFGGVWYWNRYPGLQCDNESYCYIPLLE---ELNYMPSKKF
MSMEG_5625|M.smegmatis_MC2_155      DVHIIEMGGDFGGVWYWNRYPGIQCDNESYCYIPLLE---ELGFMPSKKF
Mflv_1789|M.gilvum_PYR-GCK          GIRVIEMAGDFGGVWYWNRFPGIQCDNDAYCYIPLLE---ELGFMPSKKF
Mvan_4961|M.vanbaalenii_PYR-1       GIRVIEMAGDFGGVWYWNRFPGIQCDNDAYCYIPMLE---ELGFIPSKKF
MAB_0074c|M.abscessus_ATCC_199      -VVVFEAGSDVGGTWFFNRYPGARCDVESIDYSYSFSDELQQEWDWTEKY
MLBr_00065|M.leprae_Br4923          SYVILEKRAGMGGTWDLFRYPGIRSDSDMYTLGFRFR-----PWTKCQAI
                                       :.*   ..**.*    :**   *         :           .  

Mb1428c|M.bovis_AF2122/97           APGHELKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGGE
Rv1393c|M.tuberculosis_H37Rv        APGHELKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGGE
MAV_5206|M.avium_104                ADGAEIYQHCRNIGKHFGLYDSAIFSTQVHDLRWDEQIKRWRVSTNRGDD
TH_1337|M.thermoresistible__bu      ADGPEIYQHCRNIGKHFGLYDKAIFSTQVRSMRWDDEISRWRIGTNRGDD
MMAR_0309|M.marinum_M               ADGSEIYEHCRRIGKHYGLYDSAIFGTQVRELHWDEAIRRWRVGTNRGDD
MUL_4813|M.ulcerans_Agy99           ADGSEIYEHCRRIGKHYGLYDSAIFGTQVRELHWDEAIRRWRVGTNRGDD
MSMEG_5625|M.smegmatis_MC2_155      ADGAEIFQHCRNIGKHFGLYDGAIFSTQVRDMRWEDDLKRWRISTNRGDD
Mflv_1789|M.gilvum_PYR-GCK          ADGAEIFGHCRNIGKHFGLYDGALFSTQVRELRWDDGTQRWQISTDRGDD
Mvan_4961|M.vanbaalenii_PYR-1       ADGAEILQHCRNIGKHFGLYDGALFSTQVRELQWDDDLRRWRISTDRGDD
MAB_0074c|M.abscessus_ATCC_199      AGQKEILRYINHVADRFDLRRDIRCGTRVTSAVFDEDQLRWTVRTDRNDT
MLBr_00065|M.leprae_Br4923          ADGKPILEYIKSTAVMHGIDKYIRLNHKVTGADWSSIENRWTVQVENNGT
                                    *    :  : .     ..:      . :*    :..    * : .: .. 

Mb1428c|M.bovis_AF2122/97           ---ITARFLISACGILTVPK--LPDIDGVDSFE---GVTMHTARWDHTQD
Rv1393c|M.tuberculosis_H37Rv        ---ITARFLISACGILTVPK--LPDIDGVDSFE---GVTMHTARWDHTQD
MAV_5206|M.avium_104                ---IRARFVVLASGPFHRPK--LPGIPGIKTFG---GHSFHSSRWDYDYT
TH_1337|M.thermoresistible__bu      ---IRARFVVMASGPFHRPK--LPGIPGIKDFQ---GHSFHSSRWDYDYT
MMAR_0309|M.marinum_M               ---IRARFVVMASGPFHRPK--LPGIPGIKDFR---GHSFHSARWDYEYT
MUL_4813|M.ulcerans_Agy99           ---IRARFVVMASGPFHRPK--LPGIPGIKDFR---GHSFHPARWDYEYT
MSMEG_5625|M.smegmatis_MC2_155      ---IRARFVVMASGSFNRPK--LPGIPGIKDFG---GHIFHSSRWDYSYT
Mflv_1789|M.gilvum_PYR-GCK          ---IRARFVVMAQGSYNRPK--LPGIPGIKDFRDAGGHVFHSARWDYDYT
Mvan_4961|M.vanbaalenii_PYR-1       ---IRARFVVMAQGSYNRPK--LPGIPGIKDF---AGHVFHSARWDYDYT
MAB_0074c|M.abscessus_ATCC_199      ---VSARFCVMATGALSTAN--MPTIPGRDAFT---GELYHTGHWPASGV
MLBr_00065|M.leprae_Br4923          PRMISCSFLFLCSGYYNYEQGYAPTFLGSEDFT---GPIIHPQHWPEDLD
                                       : . * . . *     :   * : * . *    *   *. :*     

Mb1428c|M.bovis_AF2122/97           ----------LTGKRVGIIGTGASAVQVIPEMAPI-VSHLTVFQRTPIWC
Rv1393c|M.tuberculosis_H37Rv        ----------LTGKRVGIIGTGASAVQVIPEMAPI-VSHLTVFQRTPIWC
MAV_5206|M.avium_104                GGDSGGNLHKLADKRVGVVGTGATGIQIVPFLARY-AQHLYVFQRTPSTV
TH_1337|M.thermoresistible__bu      GGDTNGNLHKLADKRVAVIGTGATAIQIVPHLARD-SKHLYVFQRTPSTV
MMAR_0309|M.marinum_M               GGDSTGGLTGLADKRVAVVGTGATAVQIVPFLGRY-AKHLYVFQRTPSSV
MUL_4813|M.ulcerans_Agy99           GGDSTGGLTGLADKRVAVVGTGATAVQIVPFLGRY-AKHLYVFQRTPSSV
MSMEG_5625|M.smegmatis_MC2_155      GGDTTGNLHKLHDKKVALIGTGATGVQLVPYLGRD-AQHLYVFQRTPSTV
Mflv_1789|M.gilvum_PYR-GCK          GGDADGGLHKLADKRVALVGTGATGIQLVPHLGRD-AEHLFVFQRTPSSV
Mvan_4961|M.vanbaalenii_PYR-1       GGDADGGLHKLADKRVALVGTGATGVQLVPHLGRD-AKQLFVFQRTPSSV
MAB_0074c|M.abscessus_ATCC_199      D---------FAGKRVGVIGTGSSGIQLVPIAAQT-AKELFVFQRTANYT
MLBr_00065|M.leprae_Br4923          ----------YAAKNIVVIGSGATAVTLVPALANSGAKHVTMLQRSPTYI
                                                 *.: ::*:*::.: ::*  .    ..: ::**:.   

Mb1428c|M.bovis_AF2122/97           FPKFDVPLPTAVRWAMRIPGGKAVHR-----------------LLSQAFV
Rv1393c|M.tuberculosis_H37Rv        FPKFDVPLPTAVRWAMRIPGGKAVHR-----------------LLSQAFV
MAV_5206|M.avium_104                DARNNTPTDPEWVKTLRPGWQRERQRNFHAWT-FEGMAPGQPDLVCDFWT
TH_1337|M.thermoresistible__bu      DERNNAPTDPEWVKTLKPGWQKERQRNFHAWT-FEGMALGQPDLVCDFWT
MMAR_0309|M.marinum_M               GERNNTPTDPEWAKSLQPGWQKQRQRNFHSWT-FEGMALGQPDYVCDFWT
MUL_4813|M.ulcerans_Agy99           GERNNTPTDPEWAKSLQPGWQKQRQRNFHSWT-FEGMALGQPDYVCDFWT
MSMEG_5625|M.smegmatis_MC2_155      DERNNTPTDPEWVKTLQPGWQKERQRNFHAWT-FEGMALGQPDLVCDFWT
Mflv_1789|M.gilvum_PYR-GCK          DQRVNTPTDPDWAASLQPGWQEERKRNFHNWSPFVGVVFGEPDLVCDFWT
Mvan_4961|M.vanbaalenii_PYR-1       DERVNTPTDPAWAASLRPGWQEERKRNFHNWSPFVGVVFGEPDLVCDFWT
MAB_0074c|M.abscessus_ATCC_199      VPAGNTVISPERRAEVKANYAERRRQSRESGG--GSPHQAYPKKTLEISA
MLBr_00065|M.leprae_Br4923          VSQPAKDKIAARLNRWLPD--------------------------KYAYT
                                             .                                       .

Mb1428c|M.bovis_AF2122/97           EATFPIAAHYFAVFPLAKHMES---------------AGRRYLRQQVHDP
Rv1393c|M.tuberculosis_H37Rv        EATFPIAAHYFAVFPLAKHMES---------------AGRRYLRQQVHDP
MAV_5206|M.avium_104                ELGRNTAARVLALDDPASLTPEQFMAIREEEDYKIMERLRRRIDTLIDDP
TH_1337|M.thermoresistible__bu      ELGRNTAARVMALDDPASLTPEQFMAIREEEDFKLMERLRRRIDAIVEDP
MMAR_0309|M.marinum_M               ELGRNTAARVLALEDPAALSPEQFMAIREEEDYKVMERLRRRIQSIVDDT
MUL_4813|M.ulcerans_Agy99           ELGRNTAARVLALEDPAALSPEQFMAIREEEDYKVMERLRRRIQSIVDDT
MSMEG_5625|M.smegmatis_MC2_155      ELGRNTAARVMALEDPASMTPEQFMAIREEEDYKVMERLRRRVDQLVKDP
Mflv_1789|M.gilvum_PYR-GCK          ELGRNLTARIAGSPDPTAVTIEQIMAFREEEDYKIMERLRRRVAEIVQDP
Mvan_4961|M.vanbaalenii_PYR-1       ELGRNLTARIAASPDPAAVTIEQIMAFREEEDYKIMERLRRRVAAVVEDP
MAB_0074c|M.abscessus_ATCC_199      AERRAAFERRWELGGVLFGKTFPDQTTDMRANNEARAFFEEKVRAVIHDP
MLBr_00065|M.leprae_Br4923          AVRWKNILRQSALYGACQKWPQRMRN----------ILLGHVARRLPKGY
                                            :                               .      .. 

Mb1428c|M.bovis_AF2122/97           VVREQLTP-RYAVGCKRPGFH--NTYLSTFNRDNVRLVTEPIDKITPTAV
Rv1393c|M.tuberculosis_H37Rv        VVREQLTP-RYAVGCKRPGFH--NTYLSTFNRDNVRLVTEPIDKITPTAV
MAV_5206|M.avium_104                ATAEALKP-YYRFLCKRPCSN--DDYLPSFNRPNVTLVDVSASKGVERAT
TH_1337|M.thermoresistible__bu      ETAEKLKP-YYRFLCKRPLSN--DEYLPSFNRPNVTLVDVSESKGVERIT
MMAR_0309|M.marinum_M               STAEALKP-YYRFLCKRPCTN--DDYLQTFNRPNVTLVDVSQTRGVQRAT
MUL_4813|M.ulcerans_Agy99           STAEALKP-YYRFLCKRPCTN--DDYLQTFNRPNVTLVDVSQTRGVQRAT
MSMEG_5625|M.smegmatis_MC2_155      QTAEALKP-YYRFLCKRPCSN--DEYLSTFNRPNVTLVDVSETKGVERIT
Mflv_1789|M.gilvum_PYR-GCK          ETAEALKP-YYRFMCKRPCSS--EQYLDTFNRPNVTLVDVSESKGVERLT
Mvan_4961|M.vanbaalenii_PYR-1       ATAEALKP-YYRFMCKRPCSS--EQYLATFNRPNVTLVDVSESKGVERLT
MAB_0074c|M.abscessus_ATCC_199      AIADILVPTDHPIGTKRICTD--TNYFQTFNRDNVHVVDLRAAP-IESIN
MLBr_00065|M.leprae_Br4923          DVQKHFGP-HYNPWEQRLCLVPDGDLFRAIRKGTVDMVTDAIDRFTSTGI
                                       . : *  :    :*         : ::.: .* :*            

Mb1428c|M.bovis_AF2122/97           AT---TDGASHEIDVLVLATGFKVLDTDS--IPTYAVTGTGGASLSRFWD
Rv1393c|M.tuberculosis_H37Rv        AT---TDGASHEIDVLVLATGFKVLDTDS--IPTYAVTGTGGASLSRFWD
MAV_5206|M.avium_104                EKGLVANGVEYELDCIIYASGFEITTEISRRYSIETIAGRDGLSLFDYWR
TH_1337|M.thermoresistible__bu      PKGLVAGGIEYEVDCIIYASGFEITTDIKRRYSIDVIEGRGGVSLYDHWR
MMAR_0309|M.marinum_M               ETGLVANDTEYELDCIIYASGFEITTQISRRYSIDEIRGRDNVSLFDYWR
MUL_4813|M.ulcerans_Agy99           ETGLVANDTEYELDCIIYASGFEITTQISHRYSIDEIRGRDNVSLFDYWR
MSMEG_5625|M.smegmatis_MC2_155      QTGIVANGNEYEVDCIIFASGFEITTEIRRRFSIDSIKGRDGVSLYDHWA
Mflv_1789|M.gilvum_PYR-GCK          EKGIVANGVEYEVDCVIFASGFEISTEIHRRYAIDSVVGRDGVSLFDYWR
Mvan_4961|M.vanbaalenii_PYR-1       EKGIVANGVEYEVDCVIFASGFEISTEISRRYAIDRIVGRDGLSLFEHWR
MAB_0074c|M.abscessus_ATCC_199      RRGMTTTTKYYELDMIVFATGFDAMTGSLNRIDIR---GRAGRPLKDAWQ
MLBr_00065|M.leprae_Br4923          RLK---SGNELRADIIVTATGLNLQLFGG------AVATVDGQPVDLAQT
                                               . * :: *:*:.                  . .:     

Mb1428c|M.bovis_AF2122/97           EHRLQAYEGVSVPGYPNFFTVFGPYGY-VGSSYFALIETQAHHIIRCLKR
Rv1393c|M.tuberculosis_H37Rv        EHRLQAYEGVSVPGYPNFFTVFGPYGY-VGSSYFALIETQAHHIIRCLKR
MAV_5206|M.avium_104                DG-YKTLHGMTSRGFPNQFYTGFTQVG-ISANIAANYELQGEHIAYIIAE
TH_1337|M.thermoresistible__bu      DG-YKTFHGMTSRGFPNQFFTGFTQVG-ISANISANYELQGEHIAYIIAE
MMAR_0309|M.marinum_M               NG-YQTLHGMTSRGFPNQFFTGFTQVG-ISANIAANYELQGEHIAYIIAE
MUL_4813|M.ulcerans_Agy99           NG-YQTLHGMTSRGFPNQFFTGFTQVG-ISANIAANYELQGEHIAYIIAE
MSMEG_5625|M.smegmatis_MC2_155      DG-YKTLHGMASRGFPNQFFTGFTQVG-ISANISANYELQGEHIAYVIAE
Mflv_1789|M.gilvum_PYR-GCK          DD-YKTLHGMTSRGFPNQFFMGFIQGG-VSANTTAMFEQQAEHIAYIIAE
Mvan_4961|M.vanbaalenii_PYR-1       DD-YKTLHGMTSRGFPNQFFMGFIQGG-VSANTTAMFEQQAEHIAYIIAE
MAB_0074c|M.abscessus_ATCC_199      AG-PRTYLGLGVDGFPNLFVVTGPGSPSVLANMVLGAEQHVDWIGDLLDY
MLBr_00065|M.leprae_Br4923          MS----YKGMMLSGLPNMIYTVG----YTNASWTLKADLVSEFFCRLLNY
                                            *:   * ** :           :.     :   . :   :  

Mb1428c|M.bovis_AF2122/97           ARRTGATRIEVTEEANARYFAEVMRRRHRQVFWQDSCRLANSYYFDKNGD
Rv1393c|M.tuberculosis_H37Rv        ARRTGATRIEVTEEANARYFAEVMRRRHRQVFWQDSCRLANSYYFDKNGD
MAV_5206|M.avium_104                ALKRGAATVEPSDEAQQQWCTTIRETAVDNSAFDAQCTPGYYNNEGGGGG
TH_1337|M.thermoresistible__bu      ALNRGATVVEPTQDAQDGWCRTIRETAVDNSAFDASCTPGYYNNEGGGGG
MMAR_0309|M.marinum_M               ALARGATVVEPSQQAQDQWCRTIRETAIDNTQFDLECTPGYYNNEGGGPG
MUL_4813|M.ulcerans_Agy99           ALARGATVVEPSQQAQD---------------------------------
MSMEG_5625|M.smegmatis_MC2_155      ALNRGVTTVEPSQQAQDAWCRTIKENFVDNSAFDAECTPGYYNNEGGGGG
Mflv_1789|M.gilvum_PYR-GCK          AQNRGAAVVEPAQEAQDNWVHTVRELAIDNSAFEMSCTPGYYNNEGRGGA
Mvan_4961|M.vanbaalenii_PYR-1       AQNRGATTVEPSQEGQDNWVSTVRELAIDNSAFELSCTPGYYNNEGRGGK
MAB_0074c|M.abscessus_ATCC_199      MAAHGYSTVEAEPQAVADWVTECNERAAATMFPQANSWYLGANIPGKPRV
MLBr_00065|M.leprae_Br4923          MNANDFDTVAVEYPGSDVEERPFMDFTPGYVLRSLDALPKQGSRTPWRLN
                                        .   :     .                                   

Mb1428c|M.bovis_AF2122/97           ----------------VPLRPTTTVEAYWRSRRFDLGDYRISS---
Rv1393c|M.tuberculosis_H37Rv        ----------------VPLRPTTTVEAYWRSRRFDLGDYRISS---
MAV_5206|M.avium_104                ----EGIRSHLGEPYGPGFYAFEDLLRAWRDK-GDLEGLVLGS---
TH_1337|M.thermoresistible__bu      ----EGIRSHLGEPYGPGFYAFGDLLAEWRSK-GDLDGLELRGA--
MMAR_0309|M.marinum_M               AAEGEGIRSHIGEPYGPGFYAFGDLLAQWRSK-GDLTGLILES---
MUL_4813|M.ulcerans_Agy99           ----------------------------------------------
MSMEG_5625|M.smegmatis_MC2_155      ----EGIRSHLGEPYGPGFYAFGDLLKQWRDK-GDLDGLEIS----
Mflv_1789|M.gilvum_PYR-GCK          ----VRNGAFLGDFYSPGFYAFDELIAAWRDS-GDLEGLELS----
Mvan_4961|M.vanbaalenii_PYR-1       ----EGNGAFLGDFYSPGFYAFDELIAEWRAR-GALEGLELRG---
MAB_0074c|M.abscessus_ATCC_199      FMP-----------FIGGFGVYGAICADVAAS--GYKGFTLAGSRA
MLBr_00065|M.leprae_Br4923          ------------QNYLRDIRLIRRGKVADEGLLFAKKTTPVTV---