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M. thermoresistible (build 8) TH_1302 ()

annotation: ISONIAZID INDUCTIBLE GENE PROTEIN INIA
coordinates: 2474202 - 2476079
length: 626

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1302-100% (626)ISONIAZID INDUCTIBLE GENE PROTEIN INIA
M. thermoresistible (build 8)TH_1301-9e-1026.88% (253) ISONIAZID INDUCTIBLE GENE PROTEIN INIC

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0349iniA0.065.75% (616) isoniazid inductible gene protein INIA
M. gilvum PYR-GCKMflv_0273-0.075.71% (597) hypothetical protein Mflv_0273
M. tuberculosis H37RvRv0342iniA0.065.91% (616) isoniazid inductible gene protein INIA
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4283c-0.062.67% (600) hypothetical protein MAB_4283c
M. marinum MMMAR_0615iniA0.067.74% (620) hypothetical protein MMAR_0615
M. avium 104-----
M. smegmatis MC2 155MSMEG_0695-0.080.13% (594) isoniazid inductible protein IniA
M. ulcerans Agy99MUL_0580iniA0.067.15% (621) hypothetical protein MUL_0580
M. vanbaalenii PYR-1Mvan_0624-0.077.87% (601) hypothetical protein Mvan_0624

CLUSTAL 2.0.9 multiple sequence alignment


Mb0349|M.bovis_AF2122/97            MVPAGLCAYRDLRRKRARKWGDTVTQPDDPRR----------------VG
Rv0342|M.tuberculosis_H37Rv         MVPAGLCAYRDLRRKRARKWGDTVTQPDDPRR----------------VG
MMAR_0615|M.marinum_M               -----------------------MTQPDDPRR----------------VG
MUL_0580|M.ulcerans_Agy99           -----------------------MTQPDDPRR----------------VG
TH_1302|M.thermoresistible__bu      -----------------------MTQPNEPRPQPVPASRAPAGGPANPVP
MSMEG_0695|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0273|M.gilvum_PYR-GCK          -----------------------MTQPNDPK------------------K
Mvan_0624|M.vanbaalenii_PYR-1       -----------------------MTQPAN--------------------T
MAB_4283c|M.abscessus_ATCC_199      -----------------------MSDTAQDGQQQ--------------LA
                                                                                      

Mb0349|M.bovis_AF2122/97            VIVELIDHTIAIAKLNERGDLVQRLTRARQRITDPQVRVVIAGLLKQGKS
Rv0342|M.tuberculosis_H37Rv         VIVELIDHTIAIAKLNERGDLVQRLTRARQRITDPQVRVVIAGLLKQGKS
MMAR_0615|M.marinum_M               VIVELIDHTIAIAELNERNDLVGRLRRARQRITDPQIRVVIAGQLKQGKS
MUL_0580|M.ulcerans_Agy99           VIVELIDHTIAIAELNERNDLVGRLRRARQRITDPQIRVVIAGQLKQGKS
TH_1302|M.thermoresistible__bu      VIVELIDHTSRIAELNQRGDLAERLRRAKARITDPQIRVVIAGHLKQGKS
MSMEG_0695|M.smegmatis_MC2_155      MIVELIDHTSAIAAAKDRADLVERLRAAKARISDPQIRVVIAGQLKQGKS
Mflv_0273|M.gilvum_PYR-GCK          VVLELIEHTRKIADTQDRGDLVARLDRAARRVEDPQIRVVIAGQLKQGKS
Mvan_0624|M.vanbaalenii_PYR-1       AILELIDHASRIAQAQDRGDLTDRLARARSRLQDPQIRVVIAGQLKQGKS
MAB_4283c|M.abscessus_ATCC_199      LINELLGHVRKIAGENDRGDLIDRLDRADQLLVDRPLRVVVAGQLKQGKS
                                     : **: *.  **  ::* **  **  *   : *  :***:** ******

Mb0349|M.bovis_AF2122/97            QLLSSLLNLPAARVGDDEATVVITVVSYSAQPSARLVLAAGPD-------
Rv0342|M.tuberculosis_H37Rv         QLLNSLLNLPAARVGDDEATVVITVVSYSAQPSARLVLAAGPD-------
MMAR_0615|M.marinum_M               QLLNALLNLPVARVGDDEATVVVTVVSYSPQPSARIIVAAGPN-------
MUL_0580|M.ulcerans_Agy99           QLLNALLNLPVARVGDDEATVVVTVVSYSPQPSARIIVAAGPN-------
TH_1302|M.thermoresistible__bu      LLLNALLNMPVARVGDDESTVLTTVVSYGDQPSARLVVAQPDG-------
MSMEG_0695|M.smegmatis_MC2_155      QLLNSLLNIPVARVGDDESTVLATVVSYGEQASARLVVARPDG-------
Mflv_0273|M.gilvum_PYR-GCK          QLLNSLLNMPVARVGDDESTVVATVVSYGEQPSARLVVAGGDG-------
Mvan_0624|M.vanbaalenii_PYR-1       QLLNSLLNMPVARVGDDESTVLPTVVSYGEQASARLVVARPDG-------
MAB_4283c|M.abscessus_ATCC_199      QLVNSLLNMPVARVGDDETTSVTTVIGYGEQPSAALVVAPAEQYDGGGLA
                                     *:.:***:*.*******:* : **:.*. *.** :::*           

Mb0349|M.bovis_AF2122/97            GTTAAVDIPVDDISTDVRRAPHAGGREVLRVEVGAPSPLLRGGLAFIDTP
Rv0342|M.tuberculosis_H37Rv         GTTAAVDIPVDDISTDVRRAPHAGGREVLRVEVGAPSPLLRGGLAFIDTP
MMAR_0615|M.marinum_M               GETTSIDVPVDDINTDLRRAPQAGGREVLRVEIGAPSPLLQGGLAFIDTP
MUL_0580|M.ulcerans_Agy99           GETTSIDVPVDDINTDLRRAPQAGGREVLRVEIGAPSPLLQGGLAFIDTP
TH_1302|M.thermoresistible__bu      AEPEVVEIPTTELKNDLRRAPQARGRQVLRVEVTAPSPILKSGLAFVDTP
MSMEG_0695|M.smegmatis_MC2_155      AEPELIEIPPSEVTTDLRRAPQASGRQVLRVEVTAPSPLLKGGLAFVDTP
Mflv_0273|M.gilvum_PYR-GCK          REPELIEIPTADLRNDLRRAPQAGGREVLRVEVTAPSPLLKGGLAFIDTP
Mvan_0624|M.vanbaalenii_PYR-1       EEPELVEIPTADLRNDLRRAPQAGGREVLRVEVNAPSPLLKGGLAFIDTP
MAB_4283c|M.abscessus_ATCC_199      GEPEIIPIPVADIGKDLKRAPQAQGREVLRVEVKVASPILKSGLCLVDTP
                                      .  : :*  :: .*::***:* **:*****: ..**:*:.**.::***

Mb0349|M.bovis_AF2122/97            GVGGLGQPHLSATLGLLPEADAVLVVSDTSQEFTEPEMWFVRQAHQICPV
Rv0342|M.tuberculosis_H37Rv         GVGGLGQPHLSATLGLLPEADAVLVVSDTSQEFTEPEMWFVRQAHQICPV
MMAR_0615|M.marinum_M               GVGGHGQPHLSATLGLLPDADAMLMVSDASQEFTEPEMWFLRKAHQLCPA
MUL_0580|M.ulcerans_Agy99           GVGGHGQPHLSATLGLLPDADAMLMVSDASQEFTEPEMWFLRKAHQLCPA
TH_1302|M.thermoresistible__bu      GVGGHGQPHLSATLGLLPDADALLMISDTSQEFTEPEMRFIRQALEICPL
MSMEG_0695|M.smegmatis_MC2_155      GVGGHGQPHLSATLGLLPDADAMLMISDTSQEFTEPEMKFIRQALEICPV
Mflv_0273|M.gilvum_PYR-GCK          GVGGHGQPHLSATLGLLPDADAMLMISDVSQEFTEPEMTFMRQALDICPV
Mvan_0624|M.vanbaalenii_PYR-1       GVGGHGQPHLSATLGLLPDADAMLMISDTSQEFTEPEMTFIRQALEVCPV
MAB_4283c|M.abscessus_ATCC_199      GVGGFGQPHLSSTLGLLPDADVMLMVSDLSSEFTEPELVFIQQALDLCPV
                                    **** ******:******:**.:*::** *.******: *:::* ::** 

Mb0349|M.bovis_AF2122/97            GAVVATKTDLYPRWREIVNANAAHLQRARVPMPIIAVSSLLRSHAVTLND
Rv0342|M.tuberculosis_H37Rv         GAVVATKTDLYPRWREIVNANAAHLQRARVPMPIIAVSSLLRSHAVTLND
MMAR_0615|M.marinum_M               GVVVATKTDLYPHWREIVNTNAAHLQRARVPMPIIPVSSLLRSHAVTLND
MUL_0580|M.ulcerans_Agy99           GVVVATKTDLYPHWREIVNSNAAHLQRARVPMPIIPVSSLLRSHAVTLSE
TH_1302|M.thermoresistible__bu      ALIVATKIDLYPHWRDIMRANAEHLRRAGITTPMVPASSVLRSHAVQLND
MSMEG_0695|M.smegmatis_MC2_155      AAIVATKTDLYPHWRQIVDANIAHLQRAGLNVPVIPASSVLRSHAISLND
Mflv_0273|M.gilvum_PYR-GCK          AVIAATKTDLYPHWRRVVEANAAHLRRAGITTPMVPVSSTLRSHAVALND
Mvan_0624|M.vanbaalenii_PYR-1       ALIVGTKTDLYPHWRQVVDANRAHLQRAGVTAPLIPVSSTLRSHAVALND
MAB_4283c|M.abscessus_ATCC_199      AAIVNTKTDLYPHWRAVVAANSAHLQRAKIAVPAIAVSSALRSHALQLND
                                    . :. ** ****:** :: :*  **:** :  * :..** *****: *.:

Mb0349|M.bovis_AF2122/97            KELNEESNFPAIVKFLSEQVLSRATERVRAGVLGEIRSATEQLAVSLGSE
Rv0342|M.tuberculosis_H37Rv         KELNEESNFPAIVKFLSEQVLSRATERVRAGVLGEIRSATEQLAVSLGSE
MMAR_0615|M.marinum_M               KELNEESNFPAIVKFLSEKVLSRETDRVRDEVLREIRSAAEQLTISVDSE
MUL_0580|M.ulcerans_Agy99           KELNEESNFPAIVKFLSEKVLSRETDRVRDEVLREIRSAAEQLTISVDSE
TH_1302|M.thermoresistible__bu      KELNEESNFPAIVKFLSEQVLSGAKIRVRDQVLSDIRSAAEHLKLSIESE
MSMEG_0695|M.smegmatis_MC2_155      KELNEESNFPAIVKFLSEHVLSRQNDRIRDQIVDEIRSAAEHLLLAVESE
Mflv_0273|M.gilvum_PYR-GCK          KELNEESNFPAIVKFLSDEVLSRHNGGVREQVVAEIRAAAEHLTLAAESE
Mvan_0624|M.vanbaalenii_PYR-1       KELNEESNFPAIVKFLSEEVLASQRGRVRDQVVGEIRSAAEHLRMSVQSE
MAB_4283c|M.abscessus_ATCC_199      KELNTESNFPALVTFLSNAIADQQAS-TRQQAIAEIGSASEHLTLTLEAE
                                    **** ******:*.***: :        *   : :* :*:*:* ::  :*

Mb0349|M.bovis_AF2122/97            LSVVNDPNLRDRLASDLERRKREAQQAVQQTALWQQVLGDGFNDLTADVD
Rv0342|M.tuberculosis_H37Rv         LSVVNDPNLRDRLASDLERRKREAQQAVQQTALWQQVLGDGFNDLTADVD
MMAR_0615|M.marinum_M               LAVINDPALRDRLASDLERRKREANDALQQTALWQQVLNDGFTDLSTDVD
MUL_0580|M.ulcerans_Agy99           LAVINDPALRDRLAGDLERRKREANDALQQTALWQQVLNDGFTDLSTDVD
TH_1302|M.thermoresistible__bu      LSSLNDPEARERLTEELERRKREAQDALQQTALWQQVLNDGIADLTADVD
MSMEG_0695|M.smegmatis_MC2_155      LSSFNDPGERERLTAELERRKQEAQDALQQTALWQQVLSDGIADLTADVD
Mflv_0273|M.gilvum_PYR-GCK          RSALTDPHTRQRLTADLEARKQEAQDALQQTALWQQVLNDGIADLTADVD
Mvan_0624|M.vanbaalenii_PYR-1       LSALNDPTAREQLTADLERRKQEAQEALQHTALWQQVLNDGIADLTADVD
MAB_4283c|M.abscessus_ATCC_199      LSALQDPQSRDELTSDLERRKREAEEALAHTALWQQVLGDGITDVSTDVE
                                     : . **  *:.*: :** **:**::*: :********.**: *:::**:

Mb0349|M.bovis_AF2122/97            HDLRTRFRTVTEDAERQIDSCDPTAHWAEIGNDVENAIATAVGDNFVWAY
Rv0342|M.tuberculosis_H37Rv         HDLRTRFRTVTEDAERQIDSCDPTAHWAEIGNDVENAIATAVGDNFVWAY
MMAR_0615|M.marinum_M               HDLRARFRAVTEDAERQIDSCDPTLHWAEIGTDVENAIATAVGDNFVWAY
MUL_0580|M.ulcerans_Agy99           HDLRARFRAVTEDAERQIDSCDPTLHWAEIGTDVENAIATAVGDNFVWAY
TH_1302|M.thermoresistible__bu      HDLRQRFRNITNYTEQVIDSCDPTNHWAEIATELENAVATAVGDNFVWAY
MSMEG_0695|M.smegmatis_MC2_155      HDLRHRFRIIAAHTEKVIDGCDPTLHWAEIGAELEDAVATAVGDNFVWAY
Mflv_0273|M.gilvum_PYR-GCK          HDLRERFRNITFHTERVIETGDPTLHWAEIGAELEDAVATAVGDNFVWAY
Mvan_0624|M.vanbaalenii_PYR-1       HDLRHRFRNITFHAEEVIDSSDPTQNWAAIGAELEDAIATAVGDNFVWAY
MAB_4283c|M.abscessus_ATCC_199      HDLQSRFRRILQRTEEVIDRTDPTKNWAEVGAKLEQAVANSVGNNFVWAH
                                    ***: *** :   :*. *:  *** :** :. .:*:*:*.:**:*****:

Mb0349|M.bovis_AF2122/97            QRSEALADDVARSFADAGLDSVLSAELSPHVMGTDFGRLKALGRMESKPL
Rv0342|M.tuberculosis_H37Rv         QRSEALADDVARSFADAGLDSVLSAELSPHVMGTDFGRLKALGRMESKPL
MMAR_0615|M.marinum_M               QRGEALADDVARSFADAGLDSVLSPELSKRAMGAEFGQLKAPAQLEAKPA
MUL_0580|M.ulcerans_Agy99           QRGEALADDVAKSFADAGLDSVLSPELSKRAMGAEFGQLKAPAQLEAKPA
TH_1302|M.thermoresistible__bu      QRAEALAREVARTFVEAGLDAVPMPKIDARQMGAELGDLKSLNQLEAKPI
MSMEG_0695|M.smegmatis_MC2_155      QRAEALAAEVARTFTEAGLDAVQMPQIDARDMGAGFGELNSLARLEAKPI
Mflv_0273|M.gilvum_PYR-GCK          QRAEALAADVARTFTEAGLDAVRIPSLNARDMGADLGEFRSLAQLEAKPL
Mvan_0624|M.vanbaalenii_PYR-1       QRAEALAAEVARTFREAGLDAVRMPAIDAREMGADFGEFKSLAQLEAKPL
MAB_4283c|M.abscessus_ATCC_199      QRAMHLAAQVAETFAIDGLESIKMPRLRASEMGADLSDLKSLSKLEAKQI
                                    **.  ** :**.:*   **:::  . :    **: :. :.:  ::*:*  

Mb0349|M.bovis_AF2122/97            RRGQKMIIGMRGSYGGVVMIGMLSSVVGLGLFNPLSVGAGLILGRMAYKE
Rv0342|M.tuberculosis_H37Rv         RRGHKMIIGMRGSYGGVVMIGMLSSVVGLGLFNPLSVGAGLILGRMAYKE
MMAR_0615|M.marinum_M               GKAQKVVTGLRGSYGGVVMIGMLSSVAGLGLFNPVSVGAGLILGRMAYKE
MUL_0580|M.ulcerans_Agy99           GKAQKVVTGLRGSYGGVVMIGMLSSVAGLGLFNPVSVGAGLILGRMAYKE
TH_1302|M.thermoresistible__bu      RFGDRAVSGLRGSFGGVLMFGMLSSFAGLGMFNPLSLGAGLLMGRKTYKE
MSMEG_0695|M.smegmatis_MC2_155      KIGHKVVTGMRGSYGGVLMFGMLTSFAGLGMFNPLSLGAGFVLGRKAYKE
Mflv_0273|M.gilvum_PYR-GCK          KFGHKVVTGMRGSYGGVLIFGMLTSFAGLGMFNPLSLGAGFVLGRKAYKE
Mvan_0624|M.vanbaalenii_PYR-1       KFGHKVVTGMRGSYGGVLMFGMLTSFAGLGMFNPLSLGAGFVLGRKAYKE
MAB_4283c|M.abscessus_ATCC_199      KLGHKAITGLRGSYGGVIMFGMLTSVAGLGMFNLISLGAGAMLGKKTYNE
                                      ..: : *:***:***:::***:*..***:** :*:*** ::*: :*:*

Mb0349|M.bovis_AF2122/97            DKQNRLLRVRSEAKANVRRFVDDISFVVSKQSRDRLKMIQRLLRDHYREI
Rv0342|M.tuberculosis_H37Rv         DKQNRLLRVRSEAKANVRRFVDDISFVVSKQSRDRLKMIQRLLRDHYREI
MMAR_0615|M.marinum_M               DRENRLLRARAEAKTNVRRFVDDVSFVVGKESRDRLKMIQRTLRDHYREI
MUL_0580|M.ulcerans_Agy99           DRENRLLRARAEAKTNVRRFVDDVSFVVGKESRDRLKMIQRTLRDHYREI
TH_1302|M.thermoresistible__bu      EMENRILRIRNEAKMNVRKFVDDVAFVVSKESRDRLKGIQRMLRDYYRGI
MSMEG_0695|M.smegmatis_MC2_155      DMENRMLRVRNEAKANVRKFVDDVAFVVGKESRDRLKGIQRQLRDHYREI
Mflv_0273|M.gilvum_PYR-GCK          DMENRLLRVRNDAKTNVRRFVDDVAFAVGKESRDRLKGIQRQLRDHYREI
Mvan_0624|M.vanbaalenii_PYR-1       DMENRMLRVRSEAKANVRRFVDDVAFVVGKESRDRLKGIQRQLRDHYREI
MAB_4283c|M.abscessus_ATCC_199      DMENRMLRIRGEAKTNVRRFLDDVSFVVLKESRDRLRLVQRQLRDHFREI
                                    : :**:** * :** ***:*:**::*.* *:*****: :** ***::* *

Mb0349|M.bovis_AF2122/97            AEEITRSLTESLQATIAAAQVAETERDNRIRELQRQLGILSQVNDNLAGL
Rv0342|M.tuberculosis_H37Rv         AEEITRSLTESLQATIAAAQVAETERDNRIRELQRQLGILSQVNDNLAGL
MMAR_0615|M.marinum_M               ANEITRSLNESLQATVTASHLEEAERDNRVRELERQRNILGQVTDNLLKL
MUL_0580|M.ulcerans_Agy99           ANEITRSLNESLQATVTASHLEEAERDNRVRELERQRNILGQVTDNLLKL
TH_1302|M.thermoresistible__bu      ADQTTRSLNESLQAAIAAAKLEETERDNRVRELERQLNILNQVLDHAERL
MSMEG_0695|M.smegmatis_MC2_155      ANQTTRSLNESLQAAIAAAKVEEAERNTRVKELERQQNILKQVVDHAAKL
Mflv_0273|M.gilvum_PYR-GCK          ANQTTRSLNESLQATLSAAKMEEAERTARVRELDRQLNVLRQVIDHIDHK
Mvan_0624|M.vanbaalenii_PYR-1       ANQTTRSLNESLQATLAAAKLEETERNARVKELERQLNVLRQVLDHTEKL
MAB_4283c|M.abscessus_ATCC_199      ANQTTRSLNESLQAAIASARLEAEDRDARTNEVERQLHILRQVNSHVEGL
                                    *:: ****.*****:::::::   :*  * .*::**  :* ** .:    

Mb0349|M.bovis_AF2122/97            EPTLTPRASLGRA--
Rv0342|M.tuberculosis_H37Rv         EPTLTPRASLGRA--
MMAR_0615|M.marinum_M               GPGVSPRANLGRA--
MUL_0580|M.ulcerans_Agy99           ----SPRANLGRA--
TH_1302|M.thermoresistible__bu      ATSSG----------
MSMEG_0695|M.smegmatis_MC2_155      AQDPAPSPA------
Mflv_0273|M.gilvum_PYR-GCK          LRAPAH---------
Mvan_0624|M.vanbaalenii_PYR-1       AS-------------
MAB_4283c|M.abscessus_ATCC_199      QPADEQVGRRATRDV