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VIVELIDHTSAIAAAKDRADLVERLRAAKARISDPQIRVVIAGQLKQGKSQLLNSLLNIPVARVGDDEST VLATVVSYGEQASARLVVARPDGAEPELIEIPPSEVTTDLRRAPQASGRQVLRVEVTAPSPLLKGGLAFV DTPGVGGHGQPHLSATLGLLPDADAMLMISDTSQEFTEPEMKFIRQALEICPVAAIVATKTDLYPHWRQI VDANIAHLQRAGLNVPVIPASSVLRSHAISLNDKELNEESNFPAIVKFLSEHVLSRQNDRIRDQIVDEIR SAAEHLLLAVESELSSFNDPGERERLTAELERRKQEAQDALQQTALWQQVLSDGIADLTADVDHDLRHRF RIIAAHTEKVIDGCDPTLHWAEIGAELEDAVATAVGDNFVWAYQRAEALAAEVARTFTEAGLDAVQMPQI DARDMGAGFGELNSLARLEAKPIKIGHKVVTGMRGSYGGVLMFGMLTSFAGLGMFNPLSLGAGFVLGRKA YKEDMENRMLRVRNEAKANVRKFVDDVAFVVGKESRDRLKGIQRQLRDHYREIANQTTRSLNESLQAAIA AAKVEEAERNTRVKELERQQNILKQVVDHAAKLAQDPAPSPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0695 | - | - | 100% (602) | isoniazid inductible protein IniA |
| M. smegmatis MC2 155 | MSMEG_0698 | - | 9e-06 | 25.20% (250) | isoniazid inductible protein IniC |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0349 | iniA | 0.0 | 67.28% (599) | isoniazid inductible gene protein INIA |
| M. gilvum PYR-GCK | Mflv_0273 | - | 0.0 | 80.10% (598) | hypothetical protein Mflv_0273 |
| M. tuberculosis H37Rv | Rv0342 | iniA | 0.0 | 67.61% (599) | isoniazid inductible gene protein INIA |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4283c | - | 0.0 | 63.83% (600) | hypothetical protein MAB_4283c |
| M. marinum M | MMAR_0615 | iniA | 0.0 | 70.28% (599) | hypothetical protein MMAR_0615 |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_1302 | - | 0.0 | 80.13% (594) | ISONIAZID INDUCTIBLE GENE PROTEIN INIA |
| M. ulcerans Agy99 | MUL_0580 | iniA | 0.0 | 70.20% (594) | hypothetical protein MUL_0580 |
| M. vanbaalenii PYR-1 | Mvan_0624 | - | 0.0 | 83.64% (593) | hypothetical protein Mvan_0624 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0349|M.bovis_AF2122/97 MVPAGLCAYRDLRRKRARKWGDTVTQPDDPRR----------------VG
Rv0342|M.tuberculosis_H37Rv MVPAGLCAYRDLRRKRARKWGDTVTQPDDPRR----------------VG
MMAR_0615|M.marinum_M -----------------------MTQPDDPRR----------------VG
MUL_0580|M.ulcerans_Agy99 -----------------------MTQPDDPRR----------------VG
MSMEG_0695|M.smegmatis_MC2_155 --------------------------------------------------
TH_1302|M.thermoresistible__bu -----------------------MTQPNEPRPQPVPASRAPAGGPANPVP
Mflv_0273|M.gilvum_PYR-GCK -----------------------MTQPNDPK------------------K
Mvan_0624|M.vanbaalenii_PYR-1 -----------------------MTQPAN--------------------T
MAB_4283c|M.abscessus_ATCC_199 -----------------------MSDTAQDGQQQ--------------LA
Mb0349|M.bovis_AF2122/97 VIVELIDHTIAIAKLNERGDLVQRLTRARQRITDPQVRVVIAGLLKQGKS
Rv0342|M.tuberculosis_H37Rv VIVELIDHTIAIAKLNERGDLVQRLTRARQRITDPQVRVVIAGLLKQGKS
MMAR_0615|M.marinum_M VIVELIDHTIAIAELNERNDLVGRLRRARQRITDPQIRVVIAGQLKQGKS
MUL_0580|M.ulcerans_Agy99 VIVELIDHTIAIAELNERNDLVGRLRRARQRITDPQIRVVIAGQLKQGKS
MSMEG_0695|M.smegmatis_MC2_155 MIVELIDHTSAIAAAKDRADLVERLRAAKARISDPQIRVVIAGQLKQGKS
TH_1302|M.thermoresistible__bu VIVELIDHTSRIAELNQRGDLAERLRRAKARITDPQIRVVIAGHLKQGKS
Mflv_0273|M.gilvum_PYR-GCK VVLELIEHTRKIADTQDRGDLVARLDRAARRVEDPQIRVVIAGQLKQGKS
Mvan_0624|M.vanbaalenii_PYR-1 AILELIDHASRIAQAQDRGDLTDRLARARSRLQDPQIRVVIAGQLKQGKS
MAB_4283c|M.abscessus_ATCC_199 LINELLGHVRKIAGENDRGDLIDRLDRADQLLVDRPLRVVVAGQLKQGKS
: **: *. ** ::* ** ** * : * :***:** ******
Mb0349|M.bovis_AF2122/97 QLLSSLLNLPAARVGDDEATVVITVVSYSAQPSARLVLAAGPD-------
Rv0342|M.tuberculosis_H37Rv QLLNSLLNLPAARVGDDEATVVITVVSYSAQPSARLVLAAGPD-------
MMAR_0615|M.marinum_M QLLNALLNLPVARVGDDEATVVVTVVSYSPQPSARIIVAAGPN-------
MUL_0580|M.ulcerans_Agy99 QLLNALLNLPVARVGDDEATVVVTVVSYSPQPSARIIVAAGPN-------
MSMEG_0695|M.smegmatis_MC2_155 QLLNSLLNIPVARVGDDESTVLATVVSYGEQASARLVVARPDG-------
TH_1302|M.thermoresistible__bu LLLNALLNMPVARVGDDESTVLTTVVSYGDQPSARLVVAQPDG-------
Mflv_0273|M.gilvum_PYR-GCK QLLNSLLNMPVARVGDDESTVVATVVSYGEQPSARLVVAGGDG-------
Mvan_0624|M.vanbaalenii_PYR-1 QLLNSLLNMPVARVGDDESTVLPTVVSYGEQASARLVVARPDG-------
MAB_4283c|M.abscessus_ATCC_199 QLVNSLLNMPVARVGDDETTSVTTVIGYGEQPSAALVVAPAEQYDGGGLA
*:.:***:*.*******:* : **:.*. *.** :::*
Mb0349|M.bovis_AF2122/97 GTTAAVDIPVDDISTDVRRAPHAGGREVLRVEVGAPSPLLRGGLAFIDTP
Rv0342|M.tuberculosis_H37Rv GTTAAVDIPVDDISTDVRRAPHAGGREVLRVEVGAPSPLLRGGLAFIDTP
MMAR_0615|M.marinum_M GETTSIDVPVDDINTDLRRAPQAGGREVLRVEIGAPSPLLQGGLAFIDTP
MUL_0580|M.ulcerans_Agy99 GETTSIDVPVDDINTDLRRAPQAGGREVLRVEIGAPSPLLQGGLAFIDTP
MSMEG_0695|M.smegmatis_MC2_155 AEPELIEIPPSEVTTDLRRAPQASGRQVLRVEVTAPSPLLKGGLAFVDTP
TH_1302|M.thermoresistible__bu AEPEVVEIPTTELKNDLRRAPQARGRQVLRVEVTAPSPILKSGLAFVDTP
Mflv_0273|M.gilvum_PYR-GCK REPELIEIPTADLRNDLRRAPQAGGREVLRVEVTAPSPLLKGGLAFIDTP
Mvan_0624|M.vanbaalenii_PYR-1 EEPELVEIPTADLRNDLRRAPQAGGREVLRVEVNAPSPLLKGGLAFIDTP
MAB_4283c|M.abscessus_ATCC_199 GEPEIIPIPVADIGKDLKRAPQAQGREVLRVEVKVASPILKSGLCLVDTP
. : :* :: .*::***:* **:*****: ..**:*:.**.::***
Mb0349|M.bovis_AF2122/97 GVGGLGQPHLSATLGLLPEADAVLVVSDTSQEFTEPEMWFVRQAHQICPV
Rv0342|M.tuberculosis_H37Rv GVGGLGQPHLSATLGLLPEADAVLVVSDTSQEFTEPEMWFVRQAHQICPV
MMAR_0615|M.marinum_M GVGGHGQPHLSATLGLLPDADAMLMVSDASQEFTEPEMWFLRKAHQLCPA
MUL_0580|M.ulcerans_Agy99 GVGGHGQPHLSATLGLLPDADAMLMVSDASQEFTEPEMWFLRKAHQLCPA
MSMEG_0695|M.smegmatis_MC2_155 GVGGHGQPHLSATLGLLPDADAMLMISDTSQEFTEPEMKFIRQALEICPV
TH_1302|M.thermoresistible__bu GVGGHGQPHLSATLGLLPDADALLMISDTSQEFTEPEMRFIRQALEICPL
Mflv_0273|M.gilvum_PYR-GCK GVGGHGQPHLSATLGLLPDADAMLMISDVSQEFTEPEMTFMRQALDICPV
Mvan_0624|M.vanbaalenii_PYR-1 GVGGHGQPHLSATLGLLPDADAMLMISDTSQEFTEPEMTFIRQALEVCPV
MAB_4283c|M.abscessus_ATCC_199 GVGGFGQPHLSSTLGLLPDADVMLMVSDLSSEFTEPELVFIQQALDLCPV
**** ******:******:**.:*::** *.******: *:::* ::**
Mb0349|M.bovis_AF2122/97 GAVVATKTDLYPRWREIVNANAAHLQRARVPMPIIAVSSLLRSHAVTLND
Rv0342|M.tuberculosis_H37Rv GAVVATKTDLYPRWREIVNANAAHLQRARVPMPIIAVSSLLRSHAVTLND
MMAR_0615|M.marinum_M GVVVATKTDLYPHWREIVNTNAAHLQRARVPMPIIPVSSLLRSHAVTLND
MUL_0580|M.ulcerans_Agy99 GVVVATKTDLYPHWREIVNSNAAHLQRARVPMPIIPVSSLLRSHAVTLSE
MSMEG_0695|M.smegmatis_MC2_155 AAIVATKTDLYPHWRQIVDANIAHLQRAGLNVPVIPASSVLRSHAISLND
TH_1302|M.thermoresistible__bu ALIVATKIDLYPHWRDIMRANAEHLRRAGITTPMVPASSVLRSHAVQLND
Mflv_0273|M.gilvum_PYR-GCK AVIAATKTDLYPHWRRVVEANAAHLRRAGITTPMVPVSSTLRSHAVALND
Mvan_0624|M.vanbaalenii_PYR-1 ALIVGTKTDLYPHWRQVVDANRAHLQRAGVTAPLIPVSSTLRSHAVALND
MAB_4283c|M.abscessus_ATCC_199 AAIVNTKTDLYPHWRAVVAANSAHLQRAKIAVPAIAVSSALRSHALQLND
. :. ** ****:** :: :* **:** : * :..** *****: *.:
Mb0349|M.bovis_AF2122/97 KELNEESNFPAIVKFLSEQVLSRATERVRAGVLGEIRSATEQLAVSLGSE
Rv0342|M.tuberculosis_H37Rv KELNEESNFPAIVKFLSEQVLSRATERVRAGVLGEIRSATEQLAVSLGSE
MMAR_0615|M.marinum_M KELNEESNFPAIVKFLSEKVLSRETDRVRDEVLREIRSAAEQLTISVDSE
MUL_0580|M.ulcerans_Agy99 KELNEESNFPAIVKFLSEKVLSRETDRVRDEVLREIRSAAEQLTISVDSE
MSMEG_0695|M.smegmatis_MC2_155 KELNEESNFPAIVKFLSEHVLSRQNDRIRDQIVDEIRSAAEHLLLAVESE
TH_1302|M.thermoresistible__bu KELNEESNFPAIVKFLSEQVLSGAKIRVRDQVLSDIRSAAEHLKLSIESE
Mflv_0273|M.gilvum_PYR-GCK KELNEESNFPAIVKFLSDEVLSRHNGGVREQVVAEIRAAAEHLTLAAESE
Mvan_0624|M.vanbaalenii_PYR-1 KELNEESNFPAIVKFLSEEVLASQRGRVRDQVVGEIRSAAEHLRMSVQSE
MAB_4283c|M.abscessus_ATCC_199 KELNTESNFPALVTFLSNAIADQQAS-TRQQAIAEIGSASEHLTLTLEAE
**** ******:*.***: : * : :* :*:*:* :: :*
Mb0349|M.bovis_AF2122/97 LSVVNDPNLRDRLASDLERRKREAQQAVQQTALWQQVLGDGFNDLTADVD
Rv0342|M.tuberculosis_H37Rv LSVVNDPNLRDRLASDLERRKREAQQAVQQTALWQQVLGDGFNDLTADVD
MMAR_0615|M.marinum_M LAVINDPALRDRLASDLERRKREANDALQQTALWQQVLNDGFTDLSTDVD
MUL_0580|M.ulcerans_Agy99 LAVINDPALRDRLAGDLERRKREANDALQQTALWQQVLNDGFTDLSTDVD
MSMEG_0695|M.smegmatis_MC2_155 LSSFNDPGERERLTAELERRKQEAQDALQQTALWQQVLSDGIADLTADVD
TH_1302|M.thermoresistible__bu LSSLNDPEARERLTEELERRKREAQDALQQTALWQQVLNDGIADLTADVD
Mflv_0273|M.gilvum_PYR-GCK RSALTDPHTRQRLTADLEARKQEAQDALQQTALWQQVLNDGIADLTADVD
Mvan_0624|M.vanbaalenii_PYR-1 LSALNDPTAREQLTADLERRKQEAQEALQHTALWQQVLNDGIADLTADVD
MAB_4283c|M.abscessus_ATCC_199 LSALQDPQSRDELTSDLERRKREAEEALAHTALWQQVLGDGITDVSTDVE
: . ** *:.*: :** **:**::*: :********.**: *:::**:
Mb0349|M.bovis_AF2122/97 HDLRTRFRTVTEDAERQIDSCDPTAHWAEIGNDVENAIATAVGDNFVWAY
Rv0342|M.tuberculosis_H37Rv HDLRTRFRTVTEDAERQIDSCDPTAHWAEIGNDVENAIATAVGDNFVWAY
MMAR_0615|M.marinum_M HDLRARFRAVTEDAERQIDSCDPTLHWAEIGTDVENAIATAVGDNFVWAY
MUL_0580|M.ulcerans_Agy99 HDLRARFRAVTEDAERQIDSCDPTLHWAEIGTDVENAIATAVGDNFVWAY
MSMEG_0695|M.smegmatis_MC2_155 HDLRHRFRIIAAHTEKVIDGCDPTLHWAEIGAELEDAVATAVGDNFVWAY
TH_1302|M.thermoresistible__bu HDLRQRFRNITNYTEQVIDSCDPTNHWAEIATELENAVATAVGDNFVWAY
Mflv_0273|M.gilvum_PYR-GCK HDLRERFRNITFHTERVIETGDPTLHWAEIGAELEDAVATAVGDNFVWAY
Mvan_0624|M.vanbaalenii_PYR-1 HDLRHRFRNITFHAEEVIDSSDPTQNWAAIGAELEDAIATAVGDNFVWAY
MAB_4283c|M.abscessus_ATCC_199 HDLQSRFRRILQRTEEVIDRTDPTKNWAEVGAKLEQAVANSVGNNFVWAH
***: *** : :*. *: *** :** :. .:*:*:*.:**:*****:
Mb0349|M.bovis_AF2122/97 QRSEALADDVARSFADAGLDSVLSAELSPHVMGTDFGRLKALGRMESKPL
Rv0342|M.tuberculosis_H37Rv QRSEALADDVARSFADAGLDSVLSAELSPHVMGTDFGRLKALGRMESKPL
MMAR_0615|M.marinum_M QRGEALADDVARSFADAGLDSVLSPELSKRAMGAEFGQLKAPAQLEAKPA
MUL_0580|M.ulcerans_Agy99 QRGEALADDVAKSFADAGLDSVLSPELSKRAMGAEFGQLKAPAQLEAKPA
MSMEG_0695|M.smegmatis_MC2_155 QRAEALAAEVARTFTEAGLDAVQMPQIDARDMGAGFGELNSLARLEAKPI
TH_1302|M.thermoresistible__bu QRAEALAREVARTFVEAGLDAVPMPKIDARQMGAELGDLKSLNQLEAKPI
Mflv_0273|M.gilvum_PYR-GCK QRAEALAADVARTFTEAGLDAVRIPSLNARDMGADLGEFRSLAQLEAKPL
Mvan_0624|M.vanbaalenii_PYR-1 QRAEALAAEVARTFREAGLDAVRMPAIDAREMGADFGEFKSLAQLEAKPL
MAB_4283c|M.abscessus_ATCC_199 QRAMHLAAQVAETFAIDGLESIKMPRLRASEMGADLSDLKSLSKLEAKQI
**. ** :**.:* **::: . : **: :. :.: ::*:*
Mb0349|M.bovis_AF2122/97 RRGQKMIIGMRGSYGGVVMIGMLSSVVGLGLFNPLSVGAGLILGRMAYKE
Rv0342|M.tuberculosis_H37Rv RRGHKMIIGMRGSYGGVVMIGMLSSVVGLGLFNPLSVGAGLILGRMAYKE
MMAR_0615|M.marinum_M GKAQKVVTGLRGSYGGVVMIGMLSSVAGLGLFNPVSVGAGLILGRMAYKE
MUL_0580|M.ulcerans_Agy99 GKAQKVVTGLRGSYGGVVMIGMLSSVAGLGLFNPVSVGAGLILGRMAYKE
MSMEG_0695|M.smegmatis_MC2_155 KIGHKVVTGMRGSYGGVLMFGMLTSFAGLGMFNPLSLGAGFVLGRKAYKE
TH_1302|M.thermoresistible__bu RFGDRAVSGLRGSFGGVLMFGMLSSFAGLGMFNPLSLGAGLLMGRKTYKE
Mflv_0273|M.gilvum_PYR-GCK KFGHKVVTGMRGSYGGVLIFGMLTSFAGLGMFNPLSLGAGFVLGRKAYKE
Mvan_0624|M.vanbaalenii_PYR-1 KFGHKVVTGMRGSYGGVLMFGMLTSFAGLGMFNPLSLGAGFVLGRKAYKE
MAB_4283c|M.abscessus_ATCC_199 KLGHKAITGLRGSYGGVIMFGMLTSVAGLGMFNLISLGAGAMLGKKTYNE
..: : *:***:***:::***:*..***:** :*:*** ::*: :*:*
Mb0349|M.bovis_AF2122/97 DKQNRLLRVRSEAKANVRRFVDDISFVVSKQSRDRLKMIQRLLRDHYREI
Rv0342|M.tuberculosis_H37Rv DKQNRLLRVRSEAKANVRRFVDDISFVVSKQSRDRLKMIQRLLRDHYREI
MMAR_0615|M.marinum_M DRENRLLRARAEAKTNVRRFVDDVSFVVGKESRDRLKMIQRTLRDHYREI
MUL_0580|M.ulcerans_Agy99 DRENRLLRARAEAKTNVRRFVDDVSFVVGKESRDRLKMIQRTLRDHYREI
MSMEG_0695|M.smegmatis_MC2_155 DMENRMLRVRNEAKANVRKFVDDVAFVVGKESRDRLKGIQRQLRDHYREI
TH_1302|M.thermoresistible__bu EMENRILRIRNEAKMNVRKFVDDVAFVVSKESRDRLKGIQRMLRDYYRGI
Mflv_0273|M.gilvum_PYR-GCK DMENRLLRVRNDAKTNVRRFVDDVAFAVGKESRDRLKGIQRQLRDHYREI
Mvan_0624|M.vanbaalenii_PYR-1 DMENRMLRVRSEAKANVRRFVDDVAFVVGKESRDRLKGIQRQLRDHYREI
MAB_4283c|M.abscessus_ATCC_199 DMENRMLRIRGEAKTNVRRFLDDVSFVVLKESRDRLRLVQRQLRDHFREI
: :**:** * :** ***:*:**::*.* *:*****: :** ***::* *
Mb0349|M.bovis_AF2122/97 AEEITRSLTESLQATIAAAQVAETERDNRIRELQRQLGILSQVNDNLAGL
Rv0342|M.tuberculosis_H37Rv AEEITRSLTESLQATIAAAQVAETERDNRIRELQRQLGILSQVNDNLAGL
MMAR_0615|M.marinum_M ANEITRSLNESLQATVTASHLEEAERDNRVRELERQRNILGQVTDNLLKL
MUL_0580|M.ulcerans_Agy99 ANEITRSLNESLQATVTASHLEEAERDNRVRELERQRNILGQVTDNLLKL
MSMEG_0695|M.smegmatis_MC2_155 ANQTTRSLNESLQAAIAAAKVEEAERNTRVKELERQQNILKQVVDHAAKL
TH_1302|M.thermoresistible__bu ADQTTRSLNESLQAAIAAAKLEETERDNRVRELERQLNILNQVLDHAERL
Mflv_0273|M.gilvum_PYR-GCK ANQTTRSLNESLQATLSAAKMEEAERTARVRELDRQLNVLRQVIDHIDHK
Mvan_0624|M.vanbaalenii_PYR-1 ANQTTRSLNESLQATLAAAKLEETERNARVKELERQLNVLRQVLDHTEKL
MAB_4283c|M.abscessus_ATCC_199 ANQTTRSLNESLQAAIASARLEAEDRDARTNEVERQLHILRQVNSHVEGL
*:: ****.*****::::::: :* * .*::** :* ** .:
Mb0349|M.bovis_AF2122/97 EPTLTPRASLGRA--
Rv0342|M.tuberculosis_H37Rv EPTLTPRASLGRA--
MMAR_0615|M.marinum_M GPGVSPRANLGRA--
MUL_0580|M.ulcerans_Agy99 ----SPRANLGRA--
MSMEG_0695|M.smegmatis_MC2_155 AQDPAPSPA------
TH_1302|M.thermoresistible__bu ATSSG----------
Mflv_0273|M.gilvum_PYR-GCK LRAPAH---------
Mvan_0624|M.vanbaalenii_PYR-1 AS-------------
MAB_4283c|M.abscessus_ATCC_199 QPADEQVGRRATRDV