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M. thermoresistible (build 8) TH_1169 (-)

annotation: putative acyl-CoA dehydrogenase
coordinates: 2248481 - 2250124
length: 548

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1169--100% (548)putative acyl-CoA dehydrogenase
M. thermoresistible (build 8)TH_4603-2e-2129.70% (266) PUTATIVE acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_1915fadE152e-1926.39% (341) PROBABLE ACYL-CoA DEHYDROGENASE FADE15

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0691fadE80.084.66% (541) acyl-CoA dehydrogenase FADE8
M. gilvum PYR-GCKMflv_5086-0.084.34% (549) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv0672fadE80.084.66% (541) acyl-CoA dehydrogenase FADE8
M. leprae Br4923MLBr_02563fadE52e-1827.12% (295) acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_3860c-0.080.93% (540) acyl-CoA dehydrogenase FadE
M. marinum MMMAR_1001-0.084.84% (541) acyl-CoA dehydrogenase
M. avium 104MAV_4500-0.085.40% (541) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155MSMEG_1387-0.087.94% (539) putative acyl-CoA dehydrogenase
M. ulcerans Agy99MUL_0753-0.084.29% (541) acyl-CoA dehydrogenase
M. vanbaalenii PYR-1Mvan_1269-0.087.38% (539) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5086|M.gilvum_PYR-GCK          -----------MQDTHVVTNQVPPLVDFNPAASPVLAESLVREGGGWGAD
Mvan_1269|M.vanbaalenii_PYR-1       -----------MHDTHVVTNQVPPLEDFNPAASPVLAEALIREGGQWGAD
Mb0691|M.bovis_AF2122/97            -----------MSDTHVVTNQVPPLENYNPASSPVLIEALIQEGGQWGLD
Rv0672|M.tuberculosis_H37Rv         -----------MSDTHVVTNQVPPLENYNPASSPVLIEALIQEGGQWGLD
MAV_4500|M.avium_104                -----------MSDTHVVTNQVPPLDNYNPAGSPVLVEALIREGGQWGLD
MMAR_1001|M.marinum_M               -----------MSDTHVVTNQVPLLENHNPATSPMLVEALIREGGQWGLE
MUL_0753|M.ulcerans_Agy99           MRLLEKCNIDRMSDTHVVTNQVPLLENHNPATSPMLVEALIREGGQWGLE
TH_1169|M.thermoresistible__bu      --MADRPSFAD---THVVTNQVPPLTDHNPAASPVLTEALIGEGGQWGLD
MSMEG_1387|M.smegmatis_MC2_155      --MAHDLSLLASSGTHAVTNQVPPLEDYNPATSPVLTEALIREGGEWGLD
MAB_3860c|M.abscessus_ATCC_199      -----------MADTHVVTNQVPALRDYNAATSPVLMEALIREGGQWGVD
MLBr_02563|M.leprae_Br4923          ----------MSHYKSNVRDQVFNLFEVLGVDKAFGTDEFSNLDADTAYE
                                                  .  * :**  * :   . ...  : :   ..  . :

Mflv_5086|M.gilvum_PYR-GCK          EVADLGALAGSDRAQRWGDLADRHRPVLHTHDRYGHRVDEVEYDPAYHEL
Mvan_1269|M.vanbaalenii_PYR-1       EVAELGALAGSAAAQRWGELADRNRPVLHTHDRTGHRIDEVEYDPAYHQL
Mb0691|M.bovis_AF2122/97            EVNEVGAISASCQAQRWGELADRNRPILHTHDAYGYRVDEVEYDPAYHEL
Rv0672|M.tuberculosis_H37Rv         EVNEVGAISASCQAQRWGELADRNRPILHTHDAYGYRVDEVEYDPAYHEL
MAV_4500|M.avium_104                EVNEVGALSASRQAQRWGELADRNRPILHTHDRNGYRVDEVEYDPAYHEL
MMAR_1001|M.marinum_M               EVSELGAISGSAQAQRWGELADRNRPILHTHDRVGHRIDEVEFDPAYHEL
MUL_0753|M.ulcerans_Agy99           EVSELGAISGSAQAQRWGELADRNRPILHTHDRVGHRIDEVEFDPAYHEL
TH_1169|M.thermoresistible__bu      EVTELGALAGSAEAQRWGDLANRNRPILHTHDAVGHRIDEVEYDPAYHEL
MSMEG_1387|M.smegmatis_MC2_155      EVHALGALSGSRQAQRWGELADRNRPILHTHDRYGHRIDEVEYDPAYHEL
MAB_3860c|M.abscessus_ATCC_199      EVLEVGALNGTDRMQRAGELANRNRPVLHTHDRWGHRVDEIEFDPAYHEL
MLBr_02563|M.leprae_Br4923          MLTEVSRLAEGPVAASFAE-GDRNPPVFHPETHS------ITLPESFKKS
                                     :  :. :         .: .:*: *::*..         :    :::: 

Mflv_5086|M.gilvum_PYR-GCK          MSVAVAHGLHAAPWADDRAGAHVVRAAKTSVWTPEPGHMCPISMTYAVVP
Mvan_1269|M.vanbaalenii_PYR-1       MTVAVGHGLHAAPWADDRDGSHVVRAAKTSVWTPEPGHICPISMTYAVVP
Mb0691|M.bovis_AF2122/97            MRTAITHGMHAAPWADDRPGAHVVRAAKTSVWTVEPGHICPISMTYAVVP
Rv0672|M.tuberculosis_H37Rv         MRTAITHGMHAAPWADDRPGAHVVRAAKTSVWTVEPGHICPISMTYAVVP
MAV_4500|M.avium_104                MRTAIAHGLHAAPWADDRPGAHVVRAAKTSVWTVEPGHVCPISMTYAVVP
MMAR_1001|M.marinum_M               MRTAIGHGLHAAPWADDRPGAHVVRAAKTSVWTVEPGHICPISMTYAVVP
MUL_0753|M.ulcerans_Agy99           MRTAIGHGLHAAPWADDRPGAHVVRAAKTSVWTVEPGHICPISMTYAVVP
TH_1169|M.thermoresistible__bu      MRTAIAHGVHAAPWADERPGAHVVRAAKLSVWTPEPGHVCPISMTYAVVP
MSMEG_1387|M.smegmatis_MC2_155      MSVAVSYGLHAAPWADDRPGAHVVRAAKTSVWTPEPGHICPISMTYAVVP
MAB_3860c|M.abscessus_ATCC_199      MREAVAHGLHGAPWADERPGAHVVRAAKTGVWTADPGHMCPISMTYAVVP
MLBr_02563|M.leprae_Br4923          CRAVAEAGWSKAGIDEALGG---TPMPKALLWALHEHLMG----ANPAVW
                                       .   *   *   :   *   .  .*  :*: .   :     : ..* 

Mflv_5086|M.gilvum_PYR-GCK          ALRHNPELAAIYEPLLTSRDYDPELKLPTTKAGITAGMSMTEKQGGSDVR
Mvan_1269|M.vanbaalenii_PYR-1       ALRHNPELAAVYEPLLTSRVYDPELAVPSAKPGITAGMSMTEKQGGSDVR
Mb0691|M.bovis_AF2122/97            ALRYNSELAAVYEPLLTSREYDPELKPATTKAGITAGMSMTEKQGGSDVR
Rv0672|M.tuberculosis_H37Rv         ALRYNSELAAVYEPLLTSREYDPELKPATTKAGITAGMSMTEKQGGSDVR
MAV_4500|M.avium_104                ALRFNPELAKVYEPLLTSREYDPELRVATTKPGITAGMSMTEKQGGSDVR
MMAR_1001|M.marinum_M               ALRYNPELAAVYEPLLTSREYDPELRLASTKPGITAGMSMTEKQGGSDVR
MUL_0753|M.ulcerans_Agy99           ALRYNPELAAVYEPLLTSREYDPELRLASTKPGITAGMSMTEKQGGSDVR
TH_1169|M.thermoresistible__bu      ALRHNPELAATYEPLLTSRHYDPELKVPTTKAGITAGMSMTEKQGGSDVR
MSMEG_1387|M.smegmatis_MC2_155      ALRFNPELAKIYEPLLTSRVYDPELKIPTTKLGITAGMSMTEKQGGSDVR
MAB_3860c|M.abscessus_ATCC_199      ALRANPELAAVYEPLLSSRVYDPVLAVPTAKAGLTAGMSMTEKQGGSDVR
MLBr_02563|M.leprae_Br4923          IYAGGAGFANILYHLGTEKQKK--WAVWAAERNWGSTMVLTEPDAGSDVG
                                        .. :*     * :.:  .      ::: .  : * :** :.**** 

Mflv_5086|M.gilvum_PYR-GCK          AGTTQATPNGDGSYSLRGHKWFTSAPMCD------VFLVLAQAAGRGERS
Mvan_1269|M.vanbaalenii_PYR-1       AGTTEATPNGDGTYSLRGHKWFTSAPMCD------IFLVLAQAPG-----
Mb0691|M.bovis_AF2122/97            AGTTQATPNADGSYSLTGHKWFTSAPMCD------IFLVLAQAPD-----
Rv0672|M.tuberculosis_H37Rv         AGTTQATPNADGSYSLTGHKWFTSAPMCD------IFLVLAQAPD-----
MAV_4500|M.avium_104                AGTTQAVPNGDGSYRLTGHKWFTSAPMCD------IFLVLAQAPG-----
MMAR_1001|M.marinum_M               AGTTEATPNSDGTYRLTGHKWFTSAPMCD------IFLVLAQAPG-----
MUL_0753|M.ulcerans_Agy99           AGTTQATPNSDGTYRLTGHKWFTSAPMCD------IFLVLAQAPG-----
TH_1169|M.thermoresistible__bu      ANTTEATPNGDGSYTLVGHKWFTSAPMCD------IFLVLAQAPG-----
MSMEG_1387|M.smegmatis_MC2_155      AGTTQATPNGDGSYTLTGHKWFTSAPMCD------IFLVLAQAPG-----
MAB_3860c|M.abscessus_ATCC_199      AGTTTATPSADGSYTLVGHKWFTSAPMCD------VFLVLAQAPG-----
MLBr_02563|M.leprae_Br4923          AGRTKAVHQEDDSWHIDGVKRFITSGDSDDLFENIFHLVLARPEGAG---
                                    *. * *. . *.:: : * * * ::  .*      ..****:. .     

Mflv_5086|M.gilvum_PYR-GCK          DGGSGGLSCFFLPRILPD------GTRNRMFLQRLKDKLGNHANASSEVE
Mvan_1269|M.vanbaalenii_PYR-1       -----GLSCFFLPRILPD------GSRNRMFLQRLKDKLGNHANASSEVE
Mb0691|M.bovis_AF2122/97            -----GLSCFLLPRVLPD------GTRNRMFLQRLKDKLGNHANASSEVE
Rv0672|M.tuberculosis_H37Rv         -----GLSCFLLPRVLPD------GTRNRMFLQRLKDKLGNHANASSEVE
MAV_4500|M.avium_104                -----GLSCFLLPRVLPD------GTRNRMFLQRLKDKLGNHANASSEVE
MMAR_1001|M.marinum_M               -----GLSCFMLPRILPD------GTRNRMFLQRLKDKLGNHANASSEVE
MUL_0753|M.ulcerans_Agy99           -----GLSCFMLPHILPD------GTRNRMFLQRLKDKLGNHANASSEVE
TH_1169|M.thermoresistible__bu      -----GLSCFFLPRILPD------GTRNRMRLQRLKDKLGNHANASSEVE
MSMEG_1387|M.smegmatis_MC2_155      -----GLSCFFLPRILPD------GRRNRMFLQRLKDKLGNHANASSEVE
MAB_3860c|M.abscessus_ATCC_199      -----GLSCFFLPRVLPD------GSRNRMRLQRLKDKLGNHSNASSEVE
MLBr_02563|M.leprae_Br4923          -PGTKGLSLFFVPKFLFDFETGELGERNGVFVTNVEHKMGLKVSATCELS
                                         *** *::*:.* *      * ** : : .::.*:* : .*:.*:.

Mflv_5086|M.gilvum_PYR-GCK          YDG----ATAWLVGEEGRGVATIIEMVNLTRLDCTLGSATSMRNGLMRAA
Mvan_1269|M.vanbaalenii_PYR-1       YDG----ATAWLVGEEGRGVPTIIEMVNLTRLDCALGSATSMRNGLMRAT
Mb0691|M.bovis_AF2122/97            YDG----AVAWLVGEEGRGVPTIIEMVNLTRLDCALGSATSMRTGLTRAV
Rv0672|M.tuberculosis_H37Rv         YDG----AVAWLVGEEGRGVPTIIEMVNLTRLDCALGSATSMRTGLTRAV
MAV_4500|M.avium_104                YDG----AVAWLVGEEGRGVPTIIEMVNLTRLDCTLGSATSMRTGLTRAI
MMAR_1001|M.marinum_M               YDG----ATAWLVGEEGRGVPTIIEMVNLTRLDCTLGSATSMRSGLTRAM
MUL_0753|M.ulcerans_Agy99           YDG----ATAWLVGEEGRGVPTIIEMVNLTRLDCTLGSATSMRSGLTRAM
TH_1169|M.thermoresistible__bu      YAG----ATAWLVGEEGRGVPTIIEMVNLTRLDCTLASATSMRTGLARAI
MSMEG_1387|M.smegmatis_MC2_155      YDG----ATAWLVGEEGRGVPTIIEMVNLTRLDCTLGSATSMRNGLSRAV
MAB_3860c|M.abscessus_ATCC_199      YDE----ATAWLVGEEGKGVKTIIEMVNMTRLDCTLGSATSMRTGVALAM
MLBr_02563|M.leprae_Br4923          FGQHGVPAKGWLVGDVHDGIAQMFEVIEQARMMVGTKAIATLSTGYLNAL
                                    :      * .****:   *:  ::*::: :*:     : ::: .*   * 

Mflv_5086|M.gilvum_PYR-GCK          HHAQH------------RSAFGAYLIDQPLMRNVLADLAVEAEAATMLAM
Mvan_1269|M.vanbaalenii_PYR-1       HHAQH------------RKAFGAYLIDQPLMRNVLADLAVEAEAATMLAM
Mb0691|M.bovis_AF2122/97            HHAQH------------RKAFGAYLIDQPLMRNVLADLAVEAEAATIVAM
Rv0672|M.tuberculosis_H37Rv         HHAQH------------RKAFGAYLIDQPLMRNVLADLAVEAEAATIVAM
MAV_4500|M.avium_104                YHAQH------------RKAFGAYLIDQPLMRNVLADLAVEAEAATMVAM
MMAR_1001|M.marinum_M               HHAQH------------RKAFGAYLIDQPLMRNVLADLAVEAEAATTVAM
MUL_0753|M.ulcerans_Agy99           HHAQH------------RKAFGAYLIDQPLMRNVLADLAVEAEAATTVAM
TH_1169|M.thermoresistible__bu      HHAQH------------RKAFGAYLIDQPLMRNVLADLAVEAEAATVLAM
MSMEG_1387|M.smegmatis_MC2_155      HHAQH------------RKAFGAYLIDQPLMRNVLADLAIEAEAATMLAM
MAB_3860c|M.abscessus_ATCC_199      HHAQH------------RKAFGEYLIDQPLMRNVLADLAIEAEAATMVAM
MLBr_02563|M.leprae_Br4923          EYAKSRVQGADLTQMTDKTAPRVTITHHPDVRRSLMTQKAYAEGLRALYL
                                     :*:             :.*    : .:* :*. *      **.   : :

Mflv_5086|M.gilvum_PYR-GCK          RMAGATDHAVRGDER------ETLLRRIGLAAAKYWVCKRATPHAAEAME
Mvan_1269|M.vanbaalenii_PYR-1       RMAGATDRAVRGDER------ETLLRRIGLAAAKYWVCKRATPHAAEAME
Mb0691|M.bovis_AF2122/97            RMAGATDNAVRGNET------EALLRRIGLAAAKYWVCKRSTAHAAEALE
Rv0672|M.tuberculosis_H37Rv         RMAGATDNAVRGNET------EALLRRIGLAAAKYWVCKRSTAHAAEALE
MAV_4500|M.avium_104                RMAGATDKAVRGDQR------EALLRRIGLAASKYWVCKRSTPHAAEALE
MMAR_1001|M.marinum_M               RMAGATDKAVRGDQT------EALFRRIGLAASKYWVCKRSTPHAAEALE
MUL_0753|M.ulcerans_Agy99           RMAGATDKAVRGDQT------EALFRGIGLAASKYWVCKRSTPHAAEALE
TH_1169|M.thermoresistible__bu      RMAGATDAAARGDER------ETLLRRIGLPAAKYWVCKRATPHAAEAME
MSMEG_1387|M.smegmatis_MC2_155      RMAGATDKAVHGDER------EKLLRRIGLAAGKYWVCKRATPHAAEAME
MAB_3860c|M.abscessus_ATCC_199      RMAGATDRATRGDET------ESLLRRIGLAASKYWVCKRATPHAGEAME
MLBr_02563|M.leprae_Br4923          YTATFQDAAVAEAVHGVDAKLAVKINDLMLPLVKGVGSEQAYAKLTESLQ
                                      *   * *.              :. : *.  *   .::: .:  *:::

Mflv_5086|M.gilvum_PYR-GCK          CFGGNGYVEDSGMPRLYREAPLMGIWEGSGNVSALDTLRAMATRP-----
Mvan_1269|M.vanbaalenii_PYR-1       CLGGNGYVEDSGMPRLYREAPLMGIWEGSGNVSALDTLRAMATRP-----
Mb0691|M.bovis_AF2122/97            CLGGNGYVEDSGMPRLYREAPLMGIWEGSGNVSALDTLRAMATRP-----
Rv0672|M.tuberculosis_H37Rv         CLGGNGYVEDSGMPRLYREAPLMGIWEGSGNVSALDTLRAMATRP-----
MAV_4500|M.avium_104                CLGGNGYVEDSGMPRLYREAPLMGIWEGSGNVSALDTLRAMATRP-----
MMAR_1001|M.marinum_M               CLGGNGYVEESGMPRLYREAPLMGIWEGSGNVSALDTLRAMATKP-----
MUL_0753|M.ulcerans_Agy99           CLGGNGYVEESGMPRLYREAPLMGIWEGSGNVSALDTLRAMATKP-----
TH_1169|M.thermoresistible__bu      CLGGNGYVEDSGMPRLYREAPLMGIWEGSGNVSALDTLRAMATRP-----
MSMEG_1387|M.smegmatis_MC2_155      CLGGNGYVEDSGMPRLYREAPLMGIWEGSGNVSALDTLRAMATRP-----
MAB_3860c|M.abscessus_ATCC_199      CLGGNGYVEDSGLPRLYREAPLMGIWEGSGNVSALDTLRAMATKP-----
MLBr_02563|M.leprae_Br4923          TLGGSGFLQDYPIEQYIRDAKIDSLYEGTTAIQAQDFFFRKIVRDKGVAL
                                     :**.*::::  : :  *:* : .::**:  :.* * :    .:      

Mflv_5086|M.gilvum_PYR-GCK          ---------------------ECVDVLFDELGIATGHDPRLDRHVAGLRP
Mvan_1269|M.vanbaalenii_PYR-1       ---------------------ECIDVLFDELAATDGHDARLDAHVQGLRP
Mb0691|M.bovis_AF2122/97            ---------------------ACVEVLFDELARSAGQDPRLDGHVERLRP
Rv0672|M.tuberculosis_H37Rv         ---------------------ACVEVLFDELARSAGQDPRLDGHVERLRP
MAV_4500|M.avium_104                ---------------------ECVEVLFDELAEAAGQDPRLGGHVDRLRA
MMAR_1001|M.marinum_M               ---------------------ECVEVLFDELAHSAGQDARQDNHVEGLRR
MUL_0753|M.ulcerans_Agy99           ---------------------ECVEVLFDELAHSAGQDARQDNHVEGLRR
TH_1169|M.thermoresistible__bu      ---------------------ECVEVLFDELSRTAGQDARLDAFVATLQR
MSMEG_1387|M.smegmatis_MC2_155      ---------------------ECVEVLFDELGQTAGHDERLDAHVATLQR
MAB_3860c|M.abscessus_ATCC_199      ---------------------ECVEVLFKELALAQGQDERLDRHINGLHS
MLBr_02563|M.leprae_Br4923          SYVSGQIQQFVDSETGNGRLKSERELLAKALTDIQGMEASLTGYLMAAQQ
                                                            ::* . *    * :     .:   : 

Mflv_5086|M.gilvum_PYR-GCK          QFDDLESIQYRARQVAEDISLALQGSLLVRHGHPAVAEAFLASR------
Mvan_1269|M.vanbaalenii_PYR-1       QLGDPETIQYRARQVAEDISLALQGSLLVRHGHPAVAEAFLASR------
Mb0691|M.bovis_AF2122/97            QLGDLDTIGYRARKIAEDICLALQGSLLVRHGHPAVAEAFLATR------
Rv0672|M.tuberculosis_H37Rv         QLGDLDTIGYRARKIAEDICLALQGSLLVRHGHPAVAEAFLATR------
MAV_4500|M.avium_104                DLAELDTIQYRARKVAEDICLALQGSLLVRHGHPAVAEAFLTTR------
MMAR_1001|M.marinum_M               QLGDLETIGYRARKIAEDICLALQGSLLIRHGHPAVTEAFLATR------
MUL_0753|M.ulcerans_Agy99           QLGDLETIGYRARKIAEDICLALQGSLLIRHGHPAVTEAFLATR------
TH_1169|M.thermoresistible__bu      DLGEPD-LSYRARRVAEDIGLALQASLLVRHGHPAVTEAFLTSR------
MSMEG_1387|M.smegmatis_MC2_155      DLGELETIQYRARKVAEDISLALQGSLLVRHGHPAVAEAFLASR------
MAB_3860c|M.abscessus_ATCC_199      QLSDLESVTYRARKVAEDICLALQGALLVRHGHPAVAQAFLATR------
MLBr_02563|M.leprae_Br4923          DVTSLYKVGLGSVRFLMSVGDLIIGWLLQRQAAVAVQALDAGASSAERSF
                                    :. .   :   : :.  .:   : . ** *:.  **      :       

Mflv_5086|M.gilvum_PYR-GCK          ------LDGQWGGAFGTLPTG-LDLAPILDRALVKA---------
Mvan_1269|M.vanbaalenii_PYR-1       ------LGGQWGGAFGTLPTG-LDLAPIIERALVKAPDARRTDNR
Mb0691|M.bovis_AF2122/97            ------LGGQWGGAYGTMPAG-LDLAPILERALVKG---------
Rv0672|M.tuberculosis_H37Rv         ------LGGQWGGAYGTMPAG-LDLAPILERALVKG---------
MAV_4500|M.avium_104                ------LDRRWGGAFGTMPDG-LDLAPILERALVKG---------
MMAR_1001|M.marinum_M               ------IGGQWGGAFGTMPTG-LDLAPILERALVKG---------
MUL_0753|M.ulcerans_Agy99           ------IGGQWGGAFGTMPTG-LDLAPILERALVKG---------
TH_1169|M.thermoresistible__bu      ------LGGQWGGAFGTLPTG-LDLAPILERALVKG---------
MSMEG_1387|M.smegmatis_MC2_155      ------LGGQWGSAFGTLPTG-LDLAPIIERALVKG---------
MAB_3860c|M.abscessus_ATCC_199      ------LAGDWGGAFGTLPTG-LDLSPILERATVKSGD-------
MLBr_02563|M.leprae_Br4923          YEGKVAVSSFFAKNFLPLLTSTREVLEVLDNDIMELDEAAF----
                                          :   :.  : .:  .  ::  :::.  ::