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SDTHVVTNQVPPLDNYNPAGSPVLVEALIREGGQWGLDEVNEVGALSASRQAQRWGELADRNRPILHTHD RNGYRVDEVEYDPAYHELMRTAIAHGLHAAPWADDRPGAHVVRAAKTSVWTVEPGHVCPISMTYAVVPAL RFNPELAKVYEPLLTSREYDPELRVATTKPGITAGMSMTEKQGGSDVRAGTTQAVPNGDGSYRLTGHKWF TSAPMCDIFLVLAQAPGGLSCFLLPRVLPDGTRNRMFLQRLKDKLGNHANASSEVEYDGAVAWLVGEEGR GVPTIIEMVNLTRLDCTLGSATSMRTGLTRAIYHAQHRKAFGAYLIDQPLMRNVLADLAVEAEAATMVAM RMAGATDKAVRGDQREALLRRIGLAASKYWVCKRSTPHAAEALECLGGNGYVEDSGMPRLYREAPLMGIW EGSGNVSALDTLRAMATRPECVEVLFDELAEAAGQDPRLGGHVDRLRADLAELDTIQYRARKVAEDICLA LQGSLLVRHGHPAVAEAFLTTRLDRRWGGAFGTMPDGLDLAPILERALVKG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_4500 | - | - | 100% (542) | putative acyl-CoA dehydrogenase |
M. avium 104 | MAV_0222 | - | 1e-46 | 32.52% (412) | putative acyl-CoA dehydrogenase |
M. avium 104 | MAV_4418 | - | 5e-22 | 33.10% (281) | acyl-CoA dehydrogenase family protein member 8 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0691 | fadE8 | 0.0 | 91.14% (542) | acyl-CoA dehydrogenase FADE8 |
M. gilvum PYR-GCK | Mflv_5086 | - | 0.0 | 83.12% (551) | acyl-CoA dehydrogenase domain-containing protein |
M. tuberculosis H37Rv | Rv0672 | fadE8 | 0.0 | 91.14% (542) | acyl-CoA dehydrogenase FADE8 |
M. leprae Br4923 | MLBr_02563 | fadE5 | 3e-18 | 27.80% (295) | acyl-CoA dehydrogenase |
M. abscessus ATCC 19977 | MAB_3860c | - | 0.0 | 81.33% (541) | acyl-CoA dehydrogenase FadE |
M. marinum M | MMAR_1001 | - | 0.0 | 89.11% (542) | acyl-CoA dehydrogenase |
M. smegmatis MC2 155 | MSMEG_1387 | - | 0.0 | 87.43% (541) | putative acyl-CoA dehydrogenase |
M. thermoresistible (build 8) | TH_1169 | - | 0.0 | 85.40% (541) | putative acyl-CoA dehydrogenase |
M. ulcerans Agy99 | MUL_0753 | - | 0.0 | 88.93% (542) | acyl-CoA dehydrogenase |
M. vanbaalenii PYR-1 | Mvan_1269 | - | 0.0 | 85.03% (541) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_5086|M.gilvum_PYR-GCK -----------MQDTHVVTNQVPPLVDFNPAASPVLAESLVREGGGWGAD Mvan_1269|M.vanbaalenii_PYR-1 -----------MHDTHVVTNQVPPLEDFNPAASPVLAEALIREGGQWGAD Mb0691|M.bovis_AF2122/97 -----------MSDTHVVTNQVPPLENYNPASSPVLIEALIQEGGQWGLD Rv0672|M.tuberculosis_H37Rv -----------MSDTHVVTNQVPPLENYNPASSPVLIEALIQEGGQWGLD MAV_4500|M.avium_104 -----------MSDTHVVTNQVPPLDNYNPAGSPVLVEALIREGGQWGLD MMAR_1001|M.marinum_M -----------MSDTHVVTNQVPLLENHNPATSPMLVEALIREGGQWGLE MUL_0753|M.ulcerans_Agy99 MRLLEKCNIDRMSDTHVVTNQVPLLENHNPATSPMLVEALIREGGQWGLE MSMEG_1387|M.smegmatis_MC2_155 --MAHDLSLLASSGTHAVTNQVPPLEDYNPATSPVLTEALIREGGEWGLD TH_1169|M.thermoresistible__bu --MADRPSFAD---THVVTNQVPPLTDHNPAASPVLTEALIGEGGQWGLD MAB_3860c|M.abscessus_ATCC_199 -----------MADTHVVTNQVPALRDYNAATSPVLMEALIREGGQWGVD MLBr_02563|M.leprae_Br4923 ----------MSHYKSNVRDQVFNLFEVLGVDKAFGTDEFSNLDADTAYE . * :** * : . ... : : .. . : Mflv_5086|M.gilvum_PYR-GCK EVADLGALAGSDRAQRWGDLADRHRPVLHTHDRYGHRVDEVEYDPAYHEL Mvan_1269|M.vanbaalenii_PYR-1 EVAELGALAGSAAAQRWGELADRNRPVLHTHDRTGHRIDEVEYDPAYHQL Mb0691|M.bovis_AF2122/97 EVNEVGAISASCQAQRWGELADRNRPILHTHDAYGYRVDEVEYDPAYHEL Rv0672|M.tuberculosis_H37Rv EVNEVGAISASCQAQRWGELADRNRPILHTHDAYGYRVDEVEYDPAYHEL MAV_4500|M.avium_104 EVNEVGALSASRQAQRWGELADRNRPILHTHDRNGYRVDEVEYDPAYHEL MMAR_1001|M.marinum_M EVSELGAISGSAQAQRWGELADRNRPILHTHDRVGHRIDEVEFDPAYHEL MUL_0753|M.ulcerans_Agy99 EVSELGAISGSAQAQRWGELADRNRPILHTHDRVGHRIDEVEFDPAYHEL MSMEG_1387|M.smegmatis_MC2_155 EVHALGALSGSRQAQRWGELADRNRPILHTHDRYGHRIDEVEYDPAYHEL TH_1169|M.thermoresistible__bu EVTELGALAGSAEAQRWGDLANRNRPILHTHDAVGHRIDEVEYDPAYHEL MAB_3860c|M.abscessus_ATCC_199 EVLEVGALNGTDRMQRAGELANRNRPVLHTHDRWGHRVDEIEFDPAYHEL MLBr_02563|M.leprae_Br4923 MLTEVSRLAEGPVAASFAE-GDRNPPVFHPETHS------ITLPESFKKS : :. : .: .:*: *::*.. : :::: Mflv_5086|M.gilvum_PYR-GCK MSVAVAHGLHAAPWADDRAGAHVVRAAKTSVWTPEPGHMCPISMTYAVVP Mvan_1269|M.vanbaalenii_PYR-1 MTVAVGHGLHAAPWADDRDGSHVVRAAKTSVWTPEPGHICPISMTYAVVP Mb0691|M.bovis_AF2122/97 MRTAITHGMHAAPWADDRPGAHVVRAAKTSVWTVEPGHICPISMTYAVVP Rv0672|M.tuberculosis_H37Rv MRTAITHGMHAAPWADDRPGAHVVRAAKTSVWTVEPGHICPISMTYAVVP MAV_4500|M.avium_104 MRTAIAHGLHAAPWADDRPGAHVVRAAKTSVWTVEPGHVCPISMTYAVVP MMAR_1001|M.marinum_M MRTAIGHGLHAAPWADDRPGAHVVRAAKTSVWTVEPGHICPISMTYAVVP MUL_0753|M.ulcerans_Agy99 MRTAIGHGLHAAPWADDRPGAHVVRAAKTSVWTVEPGHICPISMTYAVVP MSMEG_1387|M.smegmatis_MC2_155 MSVAVSYGLHAAPWADDRPGAHVVRAAKTSVWTPEPGHICPISMTYAVVP TH_1169|M.thermoresistible__bu MRTAIAHGVHAAPWADERPGAHVVRAAKLSVWTPEPGHVCPISMTYAVVP MAB_3860c|M.abscessus_ATCC_199 MREAVAHGLHGAPWADERPGAHVVRAAKTGVWTADPGHMCPISMTYAVVP MLBr_02563|M.leprae_Br4923 CRAVAEAGWSKAGIDEALGG---TPMPKALLWALHEHLMG----ANPAVW . * * : * . .* :*: . : : ..* Mflv_5086|M.gilvum_PYR-GCK ALRHNPELAAIYEPLLTSRDYDPELKLPTTKAGITAGMSMTEKQGGSDVR Mvan_1269|M.vanbaalenii_PYR-1 ALRHNPELAAVYEPLLTSRVYDPELAVPSAKPGITAGMSMTEKQGGSDVR Mb0691|M.bovis_AF2122/97 ALRYNSELAAVYEPLLTSREYDPELKPATTKAGITAGMSMTEKQGGSDVR Rv0672|M.tuberculosis_H37Rv ALRYNSELAAVYEPLLTSREYDPELKPATTKAGITAGMSMTEKQGGSDVR MAV_4500|M.avium_104 ALRFNPELAKVYEPLLTSREYDPELRVATTKPGITAGMSMTEKQGGSDVR MMAR_1001|M.marinum_M ALRYNPELAAVYEPLLTSREYDPELRLASTKPGITAGMSMTEKQGGSDVR MUL_0753|M.ulcerans_Agy99 ALRYNPELAAVYEPLLTSREYDPELRLASTKPGITAGMSMTEKQGGSDVR MSMEG_1387|M.smegmatis_MC2_155 ALRFNPELAKIYEPLLTSRVYDPELKIPTTKLGITAGMSMTEKQGGSDVR TH_1169|M.thermoresistible__bu ALRHNPELAATYEPLLTSRHYDPELKVPTTKAGITAGMSMTEKQGGSDVR MAB_3860c|M.abscessus_ATCC_199 ALRANPELAAVYEPLLSSRVYDPVLAVPTAKAGLTAGMSMTEKQGGSDVR MLBr_02563|M.leprae_Br4923 IYAGGAGFANILYHLGTEKQKK--WAVWAAERNWGSTMVLTEPDAGSDVG .. :* * :.: . ::: . : * :** :.**** Mflv_5086|M.gilvum_PYR-GCK AGTTQATPNGDGSYSLRGHKWFTSAPMCD------VFLVLAQAAGRGERS Mvan_1269|M.vanbaalenii_PYR-1 AGTTEATPNGDGTYSLRGHKWFTSAPMCD------IFLVLAQAPG----- Mb0691|M.bovis_AF2122/97 AGTTQATPNADGSYSLTGHKWFTSAPMCD------IFLVLAQAPD----- Rv0672|M.tuberculosis_H37Rv AGTTQATPNADGSYSLTGHKWFTSAPMCD------IFLVLAQAPD----- MAV_4500|M.avium_104 AGTTQAVPNGDGSYRLTGHKWFTSAPMCD------IFLVLAQAPG----- MMAR_1001|M.marinum_M AGTTEATPNSDGTYRLTGHKWFTSAPMCD------IFLVLAQAPG----- MUL_0753|M.ulcerans_Agy99 AGTTQATPNSDGTYRLTGHKWFTSAPMCD------IFLVLAQAPG----- MSMEG_1387|M.smegmatis_MC2_155 AGTTQATPNGDGSYTLTGHKWFTSAPMCD------IFLVLAQAPG----- TH_1169|M.thermoresistible__bu ANTTEATPNGDGSYTLVGHKWFTSAPMCD------IFLVLAQAPG----- MAB_3860c|M.abscessus_ATCC_199 AGTTTATPSADGSYTLVGHKWFTSAPMCD------VFLVLAQAPG----- MLBr_02563|M.leprae_Br4923 AGRTKAVHQEDDSWHIDGVKRFITSGDSDDLFENIFHLVLARPEGAG--- *. * *. . *.:: : * * * :: .* ..****:. . Mflv_5086|M.gilvum_PYR-GCK DGGSGGLSCFFLPRILPD------GTRNRMFLQRLKDKLGNHANASSEVE Mvan_1269|M.vanbaalenii_PYR-1 -----GLSCFFLPRILPD------GSRNRMFLQRLKDKLGNHANASSEVE Mb0691|M.bovis_AF2122/97 -----GLSCFLLPRVLPD------GTRNRMFLQRLKDKLGNHANASSEVE Rv0672|M.tuberculosis_H37Rv -----GLSCFLLPRVLPD------GTRNRMFLQRLKDKLGNHANASSEVE MAV_4500|M.avium_104 -----GLSCFLLPRVLPD------GTRNRMFLQRLKDKLGNHANASSEVE MMAR_1001|M.marinum_M -----GLSCFMLPRILPD------GTRNRMFLQRLKDKLGNHANASSEVE MUL_0753|M.ulcerans_Agy99 -----GLSCFMLPHILPD------GTRNRMFLQRLKDKLGNHANASSEVE MSMEG_1387|M.smegmatis_MC2_155 -----GLSCFFLPRILPD------GRRNRMFLQRLKDKLGNHANASSEVE TH_1169|M.thermoresistible__bu -----GLSCFFLPRILPD------GTRNRMRLQRLKDKLGNHANASSEVE MAB_3860c|M.abscessus_ATCC_199 -----GLSCFFLPRVLPD------GSRNRMRLQRLKDKLGNHSNASSEVE MLBr_02563|M.leprae_Br4923 -PGTKGLSLFFVPKFLFDFETGELGERNGVFVTNVEHKMGLKVSATCELS *** *::*:.* * * ** : : .::.*:* : .*:.*:. Mflv_5086|M.gilvum_PYR-GCK YDG----ATAWLVGEEGRGVATIIEMVNLTRLDCTLGSATSMRNGLMRAA Mvan_1269|M.vanbaalenii_PYR-1 YDG----ATAWLVGEEGRGVPTIIEMVNLTRLDCALGSATSMRNGLMRAT Mb0691|M.bovis_AF2122/97 YDG----AVAWLVGEEGRGVPTIIEMVNLTRLDCALGSATSMRTGLTRAV Rv0672|M.tuberculosis_H37Rv YDG----AVAWLVGEEGRGVPTIIEMVNLTRLDCALGSATSMRTGLTRAV MAV_4500|M.avium_104 YDG----AVAWLVGEEGRGVPTIIEMVNLTRLDCTLGSATSMRTGLTRAI MMAR_1001|M.marinum_M YDG----ATAWLVGEEGRGVPTIIEMVNLTRLDCTLGSATSMRSGLTRAM MUL_0753|M.ulcerans_Agy99 YDG----ATAWLVGEEGRGVPTIIEMVNLTRLDCTLGSATSMRSGLTRAM MSMEG_1387|M.smegmatis_MC2_155 YDG----ATAWLVGEEGRGVPTIIEMVNLTRLDCTLGSATSMRNGLSRAV TH_1169|M.thermoresistible__bu YAG----ATAWLVGEEGRGVPTIIEMVNLTRLDCTLASATSMRTGLARAI MAB_3860c|M.abscessus_ATCC_199 YDE----ATAWLVGEEGKGVKTIIEMVNMTRLDCTLGSATSMRTGVALAM MLBr_02563|M.leprae_Br4923 FGQHGVPAKGWLVGDVHDGIAQMFEVIEQARMMVGTKAIATLSTGYLNAL : * .****: *: ::*::: :*: : ::: .* * Mflv_5086|M.gilvum_PYR-GCK HHAQH------------RSAFGAYLIDQPLMRNVLADLAVEAEAATMLAM Mvan_1269|M.vanbaalenii_PYR-1 HHAQH------------RKAFGAYLIDQPLMRNVLADLAVEAEAATMLAM Mb0691|M.bovis_AF2122/97 HHAQH------------RKAFGAYLIDQPLMRNVLADLAVEAEAATIVAM Rv0672|M.tuberculosis_H37Rv HHAQH------------RKAFGAYLIDQPLMRNVLADLAVEAEAATIVAM MAV_4500|M.avium_104 YHAQH------------RKAFGAYLIDQPLMRNVLADLAVEAEAATMVAM MMAR_1001|M.marinum_M HHAQH------------RKAFGAYLIDQPLMRNVLADLAVEAEAATTVAM MUL_0753|M.ulcerans_Agy99 HHAQH------------RKAFGAYLIDQPLMRNVLADLAVEAEAATTVAM MSMEG_1387|M.smegmatis_MC2_155 HHAQH------------RKAFGAYLIDQPLMRNVLADLAIEAEAATMLAM TH_1169|M.thermoresistible__bu HHAQH------------RKAFGAYLIDQPLMRNVLADLAVEAEAATVLAM MAB_3860c|M.abscessus_ATCC_199 HHAQH------------RKAFGEYLIDQPLMRNVLADLAIEAEAATMVAM MLBr_02563|M.leprae_Br4923 EYAKSRVQGADLTQMTDKTAPRVTITHHPDVRRSLMTQKAYAEGLRALYL :*: :.* : .:* :*. * **. : : Mflv_5086|M.gilvum_PYR-GCK RMAGATDHAVRGDER------ETLLRRIGLAAAKYWVCKRATPHAAEAME Mvan_1269|M.vanbaalenii_PYR-1 RMAGATDRAVRGDER------ETLLRRIGLAAAKYWVCKRATPHAAEAME Mb0691|M.bovis_AF2122/97 RMAGATDNAVRGNET------EALLRRIGLAAAKYWVCKRSTAHAAEALE Rv0672|M.tuberculosis_H37Rv RMAGATDNAVRGNET------EALLRRIGLAAAKYWVCKRSTAHAAEALE MAV_4500|M.avium_104 RMAGATDKAVRGDQR------EALLRRIGLAASKYWVCKRSTPHAAEALE MMAR_1001|M.marinum_M RMAGATDKAVRGDQT------EALFRRIGLAASKYWVCKRSTPHAAEALE MUL_0753|M.ulcerans_Agy99 RMAGATDKAVRGDQT------EALFRGIGLAASKYWVCKRSTPHAAEALE MSMEG_1387|M.smegmatis_MC2_155 RMAGATDKAVHGDER------EKLLRRIGLAAGKYWVCKRATPHAAEAME TH_1169|M.thermoresistible__bu RMAGATDAAARGDER------ETLLRRIGLPAAKYWVCKRATPHAAEAME MAB_3860c|M.abscessus_ATCC_199 RMAGATDRATRGDET------ESLLRRIGLAASKYWVCKRATPHAGEAME MLBr_02563|M.leprae_Br4923 YTATFQDAAVAEAVHGVDAKLAVKINDLMLPLVKGVGSEQAYAKLTESLQ * * *. :. : *. * .::: .: *::: Mflv_5086|M.gilvum_PYR-GCK CFGGNGYVEDSGMPRLYREAPLMGIWEGSGNVSALDTLRAMATRP----- Mvan_1269|M.vanbaalenii_PYR-1 CLGGNGYVEDSGMPRLYREAPLMGIWEGSGNVSALDTLRAMATRP----- Mb0691|M.bovis_AF2122/97 CLGGNGYVEDSGMPRLYREAPLMGIWEGSGNVSALDTLRAMATRP----- Rv0672|M.tuberculosis_H37Rv CLGGNGYVEDSGMPRLYREAPLMGIWEGSGNVSALDTLRAMATRP----- MAV_4500|M.avium_104 CLGGNGYVEDSGMPRLYREAPLMGIWEGSGNVSALDTLRAMATRP----- MMAR_1001|M.marinum_M CLGGNGYVEESGMPRLYREAPLMGIWEGSGNVSALDTLRAMATKP----- MUL_0753|M.ulcerans_Agy99 CLGGNGYVEESGMPRLYREAPLMGIWEGSGNVSALDTLRAMATKP----- MSMEG_1387|M.smegmatis_MC2_155 CLGGNGYVEDSGMPRLYREAPLMGIWEGSGNVSALDTLRAMATRP----- TH_1169|M.thermoresistible__bu CLGGNGYVEDSGMPRLYREAPLMGIWEGSGNVSALDTLRAMATRP----- MAB_3860c|M.abscessus_ATCC_199 CLGGNGYVEDSGLPRLYREAPLMGIWEGSGNVSALDTLRAMATKP----- MLBr_02563|M.leprae_Br4923 TLGGSGFLQDYPIEQYIRDAKIDSLYEGTTAIQAQDFFFRKIVRDKGVAL :**.*:::: : : *:* : .::**: :.* * : .: Mflv_5086|M.gilvum_PYR-GCK ---------------------ECVDVLFDELGIATGHDPRLDRHVAGLRP Mvan_1269|M.vanbaalenii_PYR-1 ---------------------ECIDVLFDELAATDGHDARLDAHVQGLRP Mb0691|M.bovis_AF2122/97 ---------------------ACVEVLFDELARSAGQDPRLDGHVERLRP Rv0672|M.tuberculosis_H37Rv ---------------------ACVEVLFDELARSAGQDPRLDGHVERLRP MAV_4500|M.avium_104 ---------------------ECVEVLFDELAEAAGQDPRLGGHVDRLRA MMAR_1001|M.marinum_M ---------------------ECVEVLFDELAHSAGQDARQDNHVEGLRR MUL_0753|M.ulcerans_Agy99 ---------------------ECVEVLFDELAHSAGQDARQDNHVEGLRR MSMEG_1387|M.smegmatis_MC2_155 ---------------------ECVEVLFDELGQTAGHDERLDAHVATLQR TH_1169|M.thermoresistible__bu ---------------------ECVEVLFDELSRTAGQDARLDAFVATLQR MAB_3860c|M.abscessus_ATCC_199 ---------------------ECVEVLFKELALAQGQDERLDRHINGLHS MLBr_02563|M.leprae_Br4923 SYVSGQIQQFVDSETGNGRLKSERELLAKALTDIQGMEASLTGYLMAAQQ ::* . * * : .: : Mflv_5086|M.gilvum_PYR-GCK QFDDLESIQYRARQVAEDISLALQGSLLVRHGHPAVAEAFLASR------ Mvan_1269|M.vanbaalenii_PYR-1 QLGDPETIQYRARQVAEDISLALQGSLLVRHGHPAVAEAFLASR------ Mb0691|M.bovis_AF2122/97 QLGDLDTIGYRARKIAEDICLALQGSLLVRHGHPAVAEAFLATR------ Rv0672|M.tuberculosis_H37Rv QLGDLDTIGYRARKIAEDICLALQGSLLVRHGHPAVAEAFLATR------ MAV_4500|M.avium_104 DLAELDTIQYRARKVAEDICLALQGSLLVRHGHPAVAEAFLTTR------ MMAR_1001|M.marinum_M QLGDLETIGYRARKIAEDICLALQGSLLIRHGHPAVTEAFLATR------ MUL_0753|M.ulcerans_Agy99 QLGDLETIGYRARKIAEDICLALQGSLLIRHGHPAVTEAFLATR------ MSMEG_1387|M.smegmatis_MC2_155 DLGELETIQYRARKVAEDISLALQGSLLVRHGHPAVAEAFLASR------ TH_1169|M.thermoresistible__bu DLGEPD-LSYRARRVAEDIGLALQASLLVRHGHPAVTEAFLTSR------ MAB_3860c|M.abscessus_ATCC_199 QLSDLESVTYRARKVAEDICLALQGALLVRHGHPAVAQAFLATR------ MLBr_02563|M.leprae_Br4923 DVTSLYKVGLGSVRFLMSVGDLIIGWLLQRQAAVAVQALDAGASSAERSF :. . : : :. .: : . ** *:. ** : Mflv_5086|M.gilvum_PYR-GCK ------LDGQWGGAFGTLPTG-LDLAPILDRALVKA--------- Mvan_1269|M.vanbaalenii_PYR-1 ------LGGQWGGAFGTLPTG-LDLAPIIERALVKAPDARRTDNR Mb0691|M.bovis_AF2122/97 ------LGGQWGGAYGTMPAG-LDLAPILERALVKG--------- Rv0672|M.tuberculosis_H37Rv ------LGGQWGGAYGTMPAG-LDLAPILERALVKG--------- MAV_4500|M.avium_104 ------LDRRWGGAFGTMPDG-LDLAPILERALVKG--------- MMAR_1001|M.marinum_M ------IGGQWGGAFGTMPTG-LDLAPILERALVKG--------- MUL_0753|M.ulcerans_Agy99 ------IGGQWGGAFGTMPTG-LDLAPILERALVKG--------- MSMEG_1387|M.smegmatis_MC2_155 ------LGGQWGSAFGTLPTG-LDLAPIIERALVKG--------- TH_1169|M.thermoresistible__bu ------LGGQWGGAFGTLPTG-LDLAPILERALVKG--------- MAB_3860c|M.abscessus_ATCC_199 ------LAGDWGGAFGTLPTG-LDLSPILERATVKSGD------- MLBr_02563|M.leprae_Br4923 YEGKVAVSSFFAKNFLPLLTSTREVLEVLDNDIMELDEAAF---- : :. : .: . :: :::. ::