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M. thermoresistible (build 8) TH_1137 ()

annotation: PROBABLE NADH PYROPHOSPHATASE NUDC (NAD+ DIPHOSPHATASE) (NAD+ PYROPHOSPHATASE) (NADP PYROPHOSPHATASE)
coordinates: 2206973 - 2207650
length: 226

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1137-100% (226)PROBABLE NADH PYROPHOSPHATASE NUDC (NAD+ DIPHOSPHATASE) (NAD+ PYROPHOSPHATASE) (NADP PYROPHOSPHATASE)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3224cnudC1e-10179.02% (224) NADH pyrophosphatase
M. gilvum PYR-GCKMflv_4662nudC1e-10881.42% (226) NADH pyrophosphatase
M. tuberculosis H37RvRv3199cnudC1e-10078.57% (224) NADH pyrophosphatase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3513cnudC3e-9471.62% (222) NADH pyrophosphatase
M. marinum MMMAR_1361nudC9e-9876.23% (223) NADH pyrophosphatase NudC
M. avium 104MAV_4145nudC1e-9874.78% (226) NADH pyrophosphatase
M. smegmatis MC2 155MSMEG_1946nudC1e-10881.42% (226) NADH pyrophosphatase
M. ulcerans Agy99MUL_2518nudC6e-9876.23% (223) NADH pyrophosphatase
M. vanbaalenii PYR-1Mvan_1805nudC1e-10981.86% (226) NADH pyrophosphatase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3224c|M.bovis_AF2122/97           MTNVSGVDFQLRSVPLLSRVGADRADRLRTDMEAAAAGWPGAALLRVDSR
Rv3199c|M.tuberculosis_H37Rv        MTNVSGVDFQLRSVPLLSRVGADRADRLRTDMEAAAAGWPGAALLRVDSR
MAV_4145|M.avium_104                ---MAIADFQLRSVPLLSRVGADRADQLRTDVEAAAAGWADAALLRVDSR
MMAR_1361|M.marinum_M               ------MDFQLREVPLLSRIGADRADHLRTDVEAAAAGWADAALMRVDSR
MUL_2518|M.ulcerans_Agy99           --MRASVDFQLREVPLLSRIGADRADHLRTDVEAAAAGWADAALMRVDSR
Mflv_4662|M.gilvum_PYR-GCK          -----MTPFRLRNIPLLSRVGADRADTLRTDIDAAVAGWSEALLLRVDRR
Mvan_1805|M.vanbaalenii_PYR-1       -----MTAFRLRNVPLLSRVGADRADTLRTDIDAAVAGWPDALLLRVDRR
MSMEG_1946|M.smegmatis_MC2_155      --MSEHRTFGLRNVPLLSRVGADRADTLRTDVDAALAGWPDALVLRVDRR
TH_1137|M.thermoresistible__bu      --------------------------------------------------
MAB_3513c|M.abscessus_ATCC_199      ------MTFRLRNIPLLSRVGLDRADELRSNPEELAKGWAEAGLITLDVR
                                                                                      

Mb3224c|M.bovis_AF2122/97           NRVLVANGRVLLGAAIELADKPPPEAVFLGRVEGGRHVWAVRAALQPIAD
Rv3199c|M.tuberculosis_H37Rv        NRVLVANGRVLLGAAIELADKPPPEAVFLGRVEGGRHVWAVRAALQPIAD
MAV_4145|M.avium_104                NQALVADGRVVLGAAAELGDKPPPEAVFLGRLEDGRHVWAIRGALQAPDD
MMAR_1361|M.marinum_M               NRVLVADGRVVLSPAADFAEKPPPEAVFLGCLEGGRHVWAVRAALEAPED
MUL_2518|M.ulcerans_Agy99           NRVLVADGRVVLSPAADFAEKPPPEAVFLGCLEGGRHVWAVRAALEAPED
Mflv_4662|M.gilvum_PYR-GCK          NQVLISDGRAVLNRAVSVGPSPPENAVFLGKLDDGRHVWAVRSDLQPPED
Mvan_1805|M.vanbaalenii_PYR-1       NQVLISGGRAVLNSASSAGAAPPEDAVFLGRLDDGRHVWAVRSELEPPED
MSMEG_1946|M.smegmatis_MC2_155      NQVLIANGQVVLGEAGALGDRPPEHAVFLGRLQDGRHVWGIRADLEAPED
TH_1137|M.thermoresistible__bu      -------------------------------------VWAVRAALEPPAD
MAB_3513c|M.abscessus_ATCC_199      GRVNIVDGQVVIEDAARIGDQPPEHAVFLGRIPGGRHVWAVRADLD--ED
                                                                         **.:*. *:   *

Mb3224c|M.bovis_AF2122/97           PDIPAEAVDLRGLGRIMDDTSSQLVSSASALLNWHDNARFSALDGAPTKP
Rv3199c|M.tuberculosis_H37Rv        PDIPAEAVDLRGLGRIMDDTSSQLVSSASALLNWHDNARFSALDGAPTKP
MAV_4145|M.avium_104                PKVRAEVVNLRSLGPIFDDTSSQLMSSAVALLNWHERSRFSSVDGSPTRP
MMAR_1361|M.marinum_M               PGAQSEVADLRKLGSIIDDTSSQLVASAMALLNWHDGSRFSPVDGSPTKP
MUL_2518|M.ulcerans_Agy99           PGAQSEVADLRKLGSIIDDTSSQLVASAMALLNWHDGSRFSPVDGSPTKP
Mflv_4662|M.gilvum_PYR-GCK          ETAPVQVLDLRRTGDVFDDVSAQLVATATALLNWHDSARFSPVDGAPTTP
Mvan_1805|M.vanbaalenii_PYR-1       PDAATEVLDLRRTGDVFDDVSAQLVATATALLNWHDHARFSPVDGAPTRP
MSMEG_1946|M.smegmatis_MC2_155      ADLGTEVLDLRRAGQIFDDTSAQLVATATALLNWHDNARHSAIDGAPTRP
TH_1137|M.thermoresistible__bu      R-PDATVLDLRRTGHIFDDVSAQLVATATALLNWHDNAKFSAIDGAPTKP
MAB_3513c|M.abscessus_ATCC_199      S---APLLDLRRSGQLFDDTSAALLATAMAMLAWHDNAGYSPVDGSPTIP
                                            :**  * ::**.*: *:::* *:* **: : .*.:**:** *

Mb3224c|M.bovis_AF2122/97           ARAGWSRVNPITGHEEFPRIDPAVICLVHDGADRAVLARQAAWPERMFSL
Rv3199c|M.tuberculosis_H37Rv        ARAGWSRVNPITGHEEFPRIDPAVICLVHDGADRAVLARQAAWPERMFSL
MAV_4145|M.avium_104                ARAGWSRVNPVTGHEEFPRIDPAVICLVHDGGDRAVLARQAVWPERMFSL
MMAR_1361|M.marinum_M               ARAGWSRVNSLTGHEEFPRIDPAVICLVHDGGDRVVLARQAIWPHRMFSL
MUL_2518|M.ulcerans_Agy99           ARAGWSRVNSLTGHEEFPRIDPAVICLVHDGGDRVVLARQAIWPHRMFSL
Mflv_4662|M.gilvum_PYR-GCK          IKSGWARINPVTGQEEFPRIDPAVICLVHDGHDRAVLARQTVWPPRLFSI
Mvan_1805|M.vanbaalenii_PYR-1       VKSGWARINPVTGHEEFPRIDPAVICLVHDGHDRAVLARQTAWPPRLFSI
MSMEG_1946|M.smegmatis_MC2_155      AKGGWSRVNPLTGHEEFPRIDPAIICLVHDGHDRAVLARQTLWPERLFSI
TH_1137|M.thermoresistible__bu      VNGGWSRVNLVNGHEEFPRIDPAVICLVHDGHDRCVLARQRLWPERFFSL
MAB_3513c|M.abscessus_ATCC_199      AKGGWVRVNSATGQEEFPRTDPAIICLVHDGGDRAVLGRQKFWPERMFSL
                                     ..** *:*  .*:***** ***:******* ** **.**  ** *:**:

Mb3224c|M.bovis_AF2122/97           LAGFVEAGESFEVCVAREIREEIGLTVRDVRYLGSQPWPFPRSLMVGFHA
Rv3199c|M.tuberculosis_H37Rv        LAGFVEAGESFEVCVAREIREEIGLTVRDVRYLGSQQWPFPRSLMVGFHA
MAV_4145|M.avium_104                LAGFVEAGESFEVCVAREVREEIGLTVRDVRYLGSQPWPFPRSLMVGFHA
MMAR_1361|M.marinum_M               LAGFVEAGESFEVCVAREIREEIGLTVRDVRYLGSQPWPLPRSLMVGFHA
MUL_2518|M.ulcerans_Agy99           LAGFVEAGESFEVCVAREIREEIGLTVRDVRYLGSQPWPLPRSLMVGFHA
Mflv_4662|M.gilvum_PYR-GCK          LAGFVEAGESFESCVVREIAEEIGLTVTDVEYLGSQPWPFPRSLMVGFHA
Mvan_1805|M.vanbaalenii_PYR-1       LAGFVEAGESFESCVVREIAEEIGLTVTDVEYLGSQPWPFPRSLMVGFHA
MSMEG_1946|M.smegmatis_MC2_155      LAGFVEAGESFETCVQREIAEEIGLTVTDVQYLGSQPWPFPRSLMVGFHA
TH_1137|M.thermoresistible__bu      VAGFVEAGESFESCVVREIAEELGLTVTDVEYLGSQPWPFPRSLMVGFHA
MAB_3513c|M.abscessus_ATCC_199      LAGFVEAGESLEACVAREVAEEVGLTVTDVQYLGSQPWPFPRSIMLGFHA
                                    :*********:* ** **: **:**** **.***** **:***:*:****

Mb3224c|M.bovis_AF2122/97           LGDPDEEFSFSDGEIAEAAWFTRDEVRAALAAGDWSSASESKLLLPGSIS
Rv3199c|M.tuberculosis_H37Rv        LGDPDEEFSFSDGEIAEAAWFTRDEVRAALAAGDWSSASESKLLLPGSIS
MAV_4145|M.avium_104                VADPAQDFAFNDGEIAEAAWFTRDEVRAALAAGDWSSDSESKLLLPGSIS
MMAR_1361|M.marinum_M               VGDPDEDFSFNDGEIAEAAWFTRDEVRAALAVGDWTSASDSKLLLPGSIS
MUL_2518|M.ulcerans_Agy99           VGDPDEDFSFNDGEIAEAAWFTRDEVRAALAVGDWTSASDSKLLLPGSIS
Mflv_4662|M.gilvum_PYR-GCK          VGDPEQPFSFNDGEIAEAQWFTRAEIRDALDQGDWSSDSSSRLLLPGSIS
Mvan_1805|M.vanbaalenii_PYR-1       IGDPEQPFAFNDGEIAEAAWFTRAEIREALAQGDWGSGGTSRLLLPGSIS
MSMEG_1946|M.smegmatis_MC2_155      IGDPEQPFSYNDGEIAEAAWFTRDEIRAALDQGDWNSDSPSRLLLPGSIS
TH_1137|M.thermoresistible__bu      VGDPDQPFSFNDGEIVEAAWFTRDEVREALAAGDWSSDSSSRLLLPGSIS
MAB_3513c|M.abscessus_ATCC_199      IGDPSQPFAFNDGEIAEADWFTRAEVRSALEAGDWTTASDSRLMLPGSIS
                                    :.** : *::.****.** **** *:* **  *** : . *:*:******

Mb3224c|M.bovis_AF2122/97           IARVIIESWAACE--------
Rv3199c|M.tuberculosis_H37Rv        IARVIIESWAACE--------
MAV_4145|M.avium_104                IARVIIESWAALD--------
MMAR_1361|M.marinum_M               IARVIIESWAAARD-------
MUL_2518|M.ulcerans_Agy99           IARVIIESWAAARD-------
Mflv_4662|M.gilvum_PYR-GCK          IAREIIESWAALD--------
Mvan_1805|M.vanbaalenii_PYR-1       IAREIIESWVERD--------
MSMEG_1946|M.smegmatis_MC2_155      IAREIIESWAALD--------
TH_1137|M.thermoresistible__bu      IAREIIESWAELD--------
MAB_3513c|M.abscessus_ATCC_199      IAREIVESWAYAGEEPPAGRP
                                    *** *:***.