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TNVSGVDFQLRSVPLLSRVGADRADRLRTDMEAAAAGWPGAALLRVDSRNRVLVANGRVLLGAAIELADK PPPEAVFLGRVEGGRHVWAVRAALQPIADPDIPAEAVDLRGLGRIMDDTSSQLVSSASALLNWHDNARFS ALDGAPTKPARAGWSRVNPITGHEEFPRIDPAVICLVHDGADRAVLARQAAWPERMFSLLAGFVEAGESF EVCVAREIREEIGLTVRDVRYLGSQQWPFPRSLMVGFHALGDPDEEFSFSDGEIAEAAWFTRDEVRAALA AGDWSSASESKLLLPGSISIARVIIESWAACE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3199c | nudC | - | 100% (313) | NADH pyrophosphatase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3224c | nudC | 1e-179 | 99.68% (313) | NADH pyrophosphatase |
| M. gilvum PYR-GCK | Mflv_4662 | nudC | 1e-127 | 69.84% (305) | NADH pyrophosphatase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3513c | nudC | 1e-114 | 64.24% (302) | NADH pyrophosphatase |
| M. marinum M | MMAR_1361 | nudC | 1e-147 | 83.28% (305) | NADH pyrophosphatase NudC |
| M. avium 104 | MAV_4145 | nudC | 1e-150 | 83.99% (306) | NADH pyrophosphatase |
| M. smegmatis MC2 155 | MSMEG_1946 | nudC | 1e-134 | 74.10% (305) | NADH pyrophosphatase |
| M. thermoresistible (build 8) | TH_1137 | - | 1e-99 | 78.57% (224) | PROBABLE NADH PYROPHOSPHATASE NUDC (NAD+ DIPHOSPHATASE) (NAD+ |
| M. ulcerans Agy99 | MUL_2518 | nudC | 1e-147 | 82.74% (307) | NADH pyrophosphatase |
| M. vanbaalenii PYR-1 | Mvan_1805 | nudC | 1e-129 | 71.76% (301) | NADH pyrophosphatase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3199c|M.tuberculosis_H37Rv MTNVSGVDFQLRSVPLLSRVGADRADRLRTDMEAAAAGWPGAALLRVDSR
Mb3224c|M.bovis_AF2122/97 MTNVSGVDFQLRSVPLLSRVGADRADRLRTDMEAAAAGWPGAALLRVDSR
MAV_4145|M.avium_104 ---MAIADFQLRSVPLLSRVGADRADQLRTDVEAAAAGWADAALLRVDSR
MMAR_1361|M.marinum_M ------MDFQLREVPLLSRIGADRADHLRTDVEAAAAGWADAALMRVDSR
MUL_2518|M.ulcerans_Agy99 --MRASVDFQLREVPLLSRIGADRADHLRTDVEAAAAGWADAALMRVDSR
Mflv_4662|M.gilvum_PYR-GCK -----MTPFRLRNIPLLSRVGADRADTLRTDIDAAVAGWSEALLLRVDRR
Mvan_1805|M.vanbaalenii_PYR-1 -----MTAFRLRNVPLLSRVGADRADTLRTDIDAAVAGWPDALLLRVDRR
MSMEG_1946|M.smegmatis_MC2_155 --MSEHRTFGLRNVPLLSRVGADRADTLRTDVDAALAGWPDALVLRVDRR
TH_1137|M.thermoresistible__bu --------------------------------------------------
MAB_3513c|M.abscessus_ATCC_199 ------MTFRLRNIPLLSRVGLDRADELRSNPEELAKGWAEAGLITLDVR
Rv3199c|M.tuberculosis_H37Rv NRVLVANGRVLLGAAIELADKPPPEAVFLGRVEGGRHVWAVRAALQPIAD
Mb3224c|M.bovis_AF2122/97 NRVLVANGRVLLGAAIELADKPPPEAVFLGRVEGGRHVWAVRAALQPIAD
MAV_4145|M.avium_104 NQALVADGRVVLGAAAELGDKPPPEAVFLGRLEDGRHVWAIRGALQAPDD
MMAR_1361|M.marinum_M NRVLVADGRVVLSPAADFAEKPPPEAVFLGCLEGGRHVWAVRAALEAPED
MUL_2518|M.ulcerans_Agy99 NRVLVADGRVVLSPAADFAEKPPPEAVFLGCLEGGRHVWAVRAALEAPED
Mflv_4662|M.gilvum_PYR-GCK NQVLISDGRAVLNRAVSVGPSPPENAVFLGKLDDGRHVWAVRSDLQPPED
Mvan_1805|M.vanbaalenii_PYR-1 NQVLISGGRAVLNSASSAGAAPPEDAVFLGRLDDGRHVWAVRSELEPPED
MSMEG_1946|M.smegmatis_MC2_155 NQVLIANGQVVLGEAGALGDRPPEHAVFLGRLQDGRHVWGIRADLEAPED
TH_1137|M.thermoresistible__bu -------------------------------------VWAVRAALEPPAD
MAB_3513c|M.abscessus_ATCC_199 GRVNIVDGQVVIEDAARIGDQPPEHAVFLGRIPGGRHVWAVRADLD--ED
**.:*. *: *
Rv3199c|M.tuberculosis_H37Rv PDIPAEAVDLRGLGRIMDDTSSQLVSSASALLNWHDNARFSALDGAPTKP
Mb3224c|M.bovis_AF2122/97 PDIPAEAVDLRGLGRIMDDTSSQLVSSASALLNWHDNARFSALDGAPTKP
MAV_4145|M.avium_104 PKVRAEVVNLRSLGPIFDDTSSQLMSSAVALLNWHERSRFSSVDGSPTRP
MMAR_1361|M.marinum_M PGAQSEVADLRKLGSIIDDTSSQLVASAMALLNWHDGSRFSPVDGSPTKP
MUL_2518|M.ulcerans_Agy99 PGAQSEVADLRKLGSIIDDTSSQLVASAMALLNWHDGSRFSPVDGSPTKP
Mflv_4662|M.gilvum_PYR-GCK ETAPVQVLDLRRTGDVFDDVSAQLVATATALLNWHDSARFSPVDGAPTTP
Mvan_1805|M.vanbaalenii_PYR-1 PDAATEVLDLRRTGDVFDDVSAQLVATATALLNWHDHARFSPVDGAPTRP
MSMEG_1946|M.smegmatis_MC2_155 ADLGTEVLDLRRAGQIFDDTSAQLVATATALLNWHDNARHSAIDGAPTRP
TH_1137|M.thermoresistible__bu R-PDATVLDLRRTGHIFDDVSAQLVATATALLNWHDNAKFSAIDGAPTKP
MAB_3513c|M.abscessus_ATCC_199 S---APLLDLRRSGQLFDDTSAALLATAMAMLAWHDNAGYSPVDGSPTIP
:** * ::**.*: *:::* *:* **: : .*.:**:** *
Rv3199c|M.tuberculosis_H37Rv ARAGWSRVNPITGHEEFPRIDPAVICLVHDGADRAVLARQAAWPERMFSL
Mb3224c|M.bovis_AF2122/97 ARAGWSRVNPITGHEEFPRIDPAVICLVHDGADRAVLARQAAWPERMFSL
MAV_4145|M.avium_104 ARAGWSRVNPVTGHEEFPRIDPAVICLVHDGGDRAVLARQAVWPERMFSL
MMAR_1361|M.marinum_M ARAGWSRVNSLTGHEEFPRIDPAVICLVHDGGDRVVLARQAIWPHRMFSL
MUL_2518|M.ulcerans_Agy99 ARAGWSRVNSLTGHEEFPRIDPAVICLVHDGGDRVVLARQAIWPHRMFSL
Mflv_4662|M.gilvum_PYR-GCK IKSGWARINPVTGQEEFPRIDPAVICLVHDGHDRAVLARQTVWPPRLFSI
Mvan_1805|M.vanbaalenii_PYR-1 VKSGWARINPVTGHEEFPRIDPAVICLVHDGHDRAVLARQTAWPPRLFSI
MSMEG_1946|M.smegmatis_MC2_155 AKGGWSRVNPLTGHEEFPRIDPAIICLVHDGHDRAVLARQTLWPERLFSI
TH_1137|M.thermoresistible__bu VNGGWSRVNLVNGHEEFPRIDPAVICLVHDGHDRCVLARQRLWPERFFSL
MAB_3513c|M.abscessus_ATCC_199 AKGGWVRVNSATGQEEFPRTDPAIICLVHDGGDRAVLGRQKFWPERMFSL
..** *:* .*:***** ***:******* ** **.** ** *:**:
Rv3199c|M.tuberculosis_H37Rv LAGFVEAGESFEVCVAREIREEIGLTVRDVRYLGSQQWPFPRSLMVGFHA
Mb3224c|M.bovis_AF2122/97 LAGFVEAGESFEVCVAREIREEIGLTVRDVRYLGSQPWPFPRSLMVGFHA
MAV_4145|M.avium_104 LAGFVEAGESFEVCVAREVREEIGLTVRDVRYLGSQPWPFPRSLMVGFHA
MMAR_1361|M.marinum_M LAGFVEAGESFEVCVAREIREEIGLTVRDVRYLGSQPWPLPRSLMVGFHA
MUL_2518|M.ulcerans_Agy99 LAGFVEAGESFEVCVAREIREEIGLTVRDVRYLGSQPWPLPRSLMVGFHA
Mflv_4662|M.gilvum_PYR-GCK LAGFVEAGESFESCVVREIAEEIGLTVTDVEYLGSQPWPFPRSLMVGFHA
Mvan_1805|M.vanbaalenii_PYR-1 LAGFVEAGESFESCVVREIAEEIGLTVTDVEYLGSQPWPFPRSLMVGFHA
MSMEG_1946|M.smegmatis_MC2_155 LAGFVEAGESFETCVQREIAEEIGLTVTDVQYLGSQPWPFPRSLMVGFHA
TH_1137|M.thermoresistible__bu VAGFVEAGESFESCVVREIAEELGLTVTDVEYLGSQPWPFPRSLMVGFHA
MAB_3513c|M.abscessus_ATCC_199 LAGFVEAGESLEACVAREVAEEVGLTVTDVQYLGSQPWPFPRSIMLGFHA
:*********:* ** **: **:**** **.***** **:***:*:****
Rv3199c|M.tuberculosis_H37Rv LGDPDEEFSFSDGEIAEAAWFTRDEVRAALAAGDWSSASESKLLLPGSIS
Mb3224c|M.bovis_AF2122/97 LGDPDEEFSFSDGEIAEAAWFTRDEVRAALAAGDWSSASESKLLLPGSIS
MAV_4145|M.avium_104 VADPAQDFAFNDGEIAEAAWFTRDEVRAALAAGDWSSDSESKLLLPGSIS
MMAR_1361|M.marinum_M VGDPDEDFSFNDGEIAEAAWFTRDEVRAALAVGDWTSASDSKLLLPGSIS
MUL_2518|M.ulcerans_Agy99 VGDPDEDFSFNDGEIAEAAWFTRDEVRAALAVGDWTSASDSKLLLPGSIS
Mflv_4662|M.gilvum_PYR-GCK VGDPEQPFSFNDGEIAEAQWFTRAEIRDALDQGDWSSDSSSRLLLPGSIS
Mvan_1805|M.vanbaalenii_PYR-1 IGDPEQPFAFNDGEIAEAAWFTRAEIREALAQGDWGSGGTSRLLLPGSIS
MSMEG_1946|M.smegmatis_MC2_155 IGDPEQPFSYNDGEIAEAAWFTRDEIRAALDQGDWNSDSPSRLLLPGSIS
TH_1137|M.thermoresistible__bu VGDPDQPFSFNDGEIVEAAWFTRDEVREALAAGDWSSDSSSRLLLPGSIS
MAB_3513c|M.abscessus_ATCC_199 IGDPSQPFAFNDGEIAEADWFTRAEVRSALEAGDWTTASDSRLMLPGSIS
:.** : *::.****.** **** *:* ** *** : . *:*:******
Rv3199c|M.tuberculosis_H37Rv IARVIIESWAACE--------
Mb3224c|M.bovis_AF2122/97 IARVIIESWAACE--------
MAV_4145|M.avium_104 IARVIIESWAALD--------
MMAR_1361|M.marinum_M IARVIIESWAAARD-------
MUL_2518|M.ulcerans_Agy99 IARVIIESWAAARD-------
Mflv_4662|M.gilvum_PYR-GCK IAREIIESWAALD--------
Mvan_1805|M.vanbaalenii_PYR-1 IAREIIESWVERD--------
MSMEG_1946|M.smegmatis_MC2_155 IAREIIESWAALD--------
TH_1137|M.thermoresistible__bu IAREIIESWAELD--------
MAB_3513c|M.abscessus_ATCC_199 IAREIVESWAYAGEEPPAGRP
*** *:***.