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M. thermoresistible (build 8) TH_1102 (aroG)

annotation: Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG (DAHP synthetase, phenylalanine-repressible)
coordinates: 2159576 - 2160961
length: 462

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_1102 aroG - 100% (462) Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG (DAHP synthetase, phenylalanine-repressible)

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2200c aroG 0.0 88.10% (462) 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG
M. gilvum PYR-GCK Mflv_2971 - 0.0 90.00% (470) phospho-2-dehydro-3-deoxyheptonate aldolase
M. tuberculosis H37Rv Rv2178c aroG 0.0 87.88% (462) 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG
M. leprae Br4923 MLBr_00896 aroG 0.0 87.10% (465) 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (DAHP
M. abscessus ATCC 19977 MAB_1987 - 0.0 87.66% (462) 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG
M. marinum M MMAR_3222 aroG 0.0 88.53% (462) 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG
M. avium 104 MAV_2317 - 0.0 88.96% (462) 3-deoxy-7-phosphoheptulonate synthase
M. smegmatis MC2 155 MSMEG_4244 - 0.0 90.95% (464) 3-deoxy-7-phosphoheptulonate synthase
M. ulcerans Agy99 MUL_3533 aroG_1 0.0 88.10% (462) 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase
M. vanbaalenii PYR-1 Mvan_3540 - 0.0 89.29% (467) phospho-2-dehydro-3-deoxyheptonate aldolase

CLUSTAL 2.0.9 multiple sequence alignment


TH_1102|M.thermoresistible__bu      VNWTVDVPIDQLPALPPLPADLRQRLDAALAKPALQQPSWDPDLAKAMRT
MSMEG_4244|M.smegmatis_MC2_155      MNWTVDIPIDQLPPLPPLSDELRQRLDSALAKPAVQQPSWDPDAAKAMRT
Mflv_2971|M.gilvum_PYR-GCK          MNWTVDVPIDQLPALPPLPADLRQRLDAALAKPALQQPSWDAGQAAAMRK
Mvan_3540|M.vanbaalenii_PYR-1       MNWTVDVPIDQLPALPPLPEDLRQRLDAALARPALQQPSWDAGQAAAMRK
MMAR_3222|M.marinum_M               MNWTVDIPIDQLPSLPPLSDELRARLDAALAKPAAQQPSWPVDQATAMRK
MUL_3533|M.ulcerans_Agy99           MNWTVDIPIDQLPSLPPLSDELRARLDAALAKPAAQQPSWPVDQATAMRK
Mb2200c|M.bovis_AF2122/97           MNWTVDIPIDQLPSLPPLPTDLRTRLDAALAKPAAQQPTWPADQALAMRT
Rv2178c|M.tuberculosis_H37Rv        MNWTVDIPIDQLPSLPPLPTDLRTRLDAALAKPAAQQPTWPADQALAMRT
MAV_2317|M.avium_104                MNWTVDIPIDQLPPLPPLPGDLRARLDAALAKPAAQQPSWPTDQATAMRT
MLBr_00896|M.leprae_Br4923          MNWTVDIPIDQLP---PLPADLRARLDAALAKPAAQQPSWPTDQAAAMRT
MAB_1987|M.abscessus_ATCC_1997      MNWTVDVPIDQLPELPPLPADLRERLDAALAKPAAQQPSWPANQAAAMRT
                                    :*****:******   **. :** ***:***:** ***:*  . * ***.

TH_1102|M.thermoresistible__bu      VLESVPPITVPSEVERLKSLLGEVARGKAFLLQGGDCAETFVDNTEPHIK
MSMEG_4244|M.smegmatis_MC2_155      VLESVPPVTVPSEIEKLKGLLADVAQGKAFLLQGGDCAETFVDNTEPHIR
Mflv_2971|M.gilvum_PYR-GCK          VLESVPPVTVPSEIERLKGQLADVALGKAFLLQGGDCAETFVDNTEPHIR
Mvan_3540|M.vanbaalenii_PYR-1       VLESVPPVTVPSEIERLKSQLADVARGQAFLLQGGDCAETFVDNTEPHIR
MMAR_3222|M.marinum_M               VLESVPPVTVPSEIIRLQEQLAQVARGEAFLLQGGDCAETFTDNTEPHIR
MUL_3533|M.ulcerans_Agy99           VLESVPPVTVPSEIIRLQEQLAQVAGGEAFLLQGGDCAETFTDNTEPHIR
Mb2200c|M.bovis_AF2122/97           VLESVPPVTVPSEIVRLQEQLAQVAKGEAFLLQGGDCAETFMDNTEPHIR
Rv2178c|M.tuberculosis_H37Rv        VLESVPPVTVPSEIVRLQEQLAQVAKGEAFLLQGGDCAETFMDNTEPHIR
MAV_2317|M.avium_104                VLESVPPVTVPSEIVRLQEQLAQVARGEAFLLQGGDCAETFTENTEPHIR
MLBr_00896|M.leprae_Br4923          VLESVPPVTVPSEIIRLQEQLALVANGKAFLLQGGDCAETFVDNTEPHIR
MAB_1987|M.abscessus_ATCC_1997      VLESVPPITVPAEIQRLQRQLAQVARGEAFLLQGGDCAETFADNTEPHIR
                                    *******:***:*: :*:  *. ** *:************* :******:

TH_1102|M.thermoresistible__bu      ANIRTLLQMAVVLTYGASTPVVKMARIAGQYAKPRSSDTDALGLKSYRGD
MSMEG_4244|M.smegmatis_MC2_155      ANIRTLLQMAVVLTYGASMPVVKVARIAGQYAKPRSSDVDALGLKSYRGD
Mflv_2971|M.gilvum_PYR-GCK          ANIRTLLQMAVVLTYGASMPVVKVARIAGQYAKPRSSDVDALGLKSYRGD
Mvan_3540|M.vanbaalenii_PYR-1       ANIRTLLQMAVVLTYGASMPVVKVARIAGQYAKPRSSDTDALGLKSYRGD
MMAR_3222|M.marinum_M               GNVRTLLQMAVVLTYGSSMPVVKVARIAGQYAKPRSADTDALGLKSYRGD
MUL_3533|M.ulcerans_Agy99           GNVRTLLQMAVVLTYGSSMPVVKVARIAGQYAKPRSADTDALGLKSYRGD
Mb2200c|M.bovis_AF2122/97           GNVRALLQMAVVLTYGASMPVVKVARIAGQYAKPRSADIDALGLRSYRGD
Rv2178c|M.tuberculosis_H37Rv        GNVRALLQMAVVLTYGASMPVVKVARIAGQYAKPRSADIDALGLRSYRGD
MAV_2317|M.avium_104                GNIRTLLQMAVVLTYGASMPVVKVARIAGQYAKPRSADIDALGLKSYRGD
MLBr_00896|M.leprae_Br4923          SNVRTLLQMAVVLTYGASLPVVKVARIAGQYAKPRSADVDALGLKSYRGD
MAB_1987|M.abscessus_ATCC_1997      ANIRALLQMAVVLTYGASMPVVKLARIAGQYAKPRSSDTDALGLKSYRGD
                                    .*:*:***********:* ****:************:* *****:*****

TH_1102|M.thermoresistible__bu      MINGFAPDASAREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDW
MSMEG_4244|M.smegmatis_MC2_155      MINGFAPDAAAREHDPSRLVRAYANASAAMNLMRALTSSGLASLHLVHEW
Mflv_2971|M.gilvum_PYR-GCK          MVNGFAPDAAVRDHDPSRLVRAYANASAAMNLVRALTSSGMASLHQVHDW
Mvan_3540|M.vanbaalenii_PYR-1       MVNGFAPDAAVREHDPSRLVRAYANASAAMNLVRALTSSGMASLHQVHDW
MMAR_3222|M.marinum_M               MINGFPPDAAAREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDW
MUL_3533|M.ulcerans_Agy99           MINGFPPDAAAREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDW
Mb2200c|M.bovis_AF2122/97           MINGFAPDAAAREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDW
Rv2178c|M.tuberculosis_H37Rv        MINGFAPDAAAREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDW
MAV_2317|M.avium_104                MINGFAPNAAVREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDW
MLBr_00896|M.leprae_Br4923          MINGFAPDAAAREHDPSRLVRAYANSSAAMNLVRALTSSGLASLHLVHDW
MAB_1987|M.abscessus_ATCC_1997      MVNGFAPDATLREHDPSRLVRAYANASAAMNLVRALTGSGMASLALVHDW
                                    *:***.*:*: *:************:******:****.**:***  **:*

TH_1102|M.thermoresistible__bu      NREFVRTSPAGARYEALAGEIDRGLRFMSACGVADRNLQTAEIYASHEAL
MSMEG_4244|M.smegmatis_MC2_155      NREFVRTSPAGARYEALAGEIDRGLNFMSACGVADRNLQTAEIFASHEAL
Mflv_2971|M.gilvum_PYR-GCK          NREFVRTSPAGARYEALAGEIDRGLRFMSACRVDDRNLDTAEIYASHEAL
Mvan_3540|M.vanbaalenii_PYR-1       NREFVRTSPAGARYEALAGEIDRGLRFMSACRVDDRNLDTAEIYASHEAL
MMAR_3222|M.marinum_M               NREFVRTSPAGARYEALANEIDRGLRFMSACGVADRNLQTAEIYASHEAL
MUL_3533|M.ulcerans_Agy99           NREFVRTSPAGARYEALANEIDRGLRFMSACGVADRNLQTAEIYASHEAL
Mb2200c|M.bovis_AF2122/97           NREFVRTSPAGARYEALATEIDRGLRFMSACGVADRNLQTAEIYASHEAL
Rv2178c|M.tuberculosis_H37Rv        NREFVRTSPAGARYEALATEIDRGLRFMSACGVADRNLQTAEIYASHEAL
MAV_2317|M.avium_104                NREFVRTSPAGARYEALATEIDRGLRFMSACGVADRNLQTAEIYASHEAL
MLBr_00896|M.leprae_Br4923          NREFVRTSPAGARYEALAGEIGRGLAFMSACGVADRNLQTAEIYASHEAL
MAB_1987|M.abscessus_ATCC_1997      NREFVRTSPAGARYEALAGEIDRGLKFMSACGVVDSNLDTAEIYASHEAL
                                    ****************** **.*** ***** * * **:****:******

TH_1102|M.thermoresistible__bu      VLDYERAMLRLS---EETGE----PKLYDLSAHYLWIGERTRQLDGAHIA
MSMEG_4244|M.smegmatis_MC2_155      VLDYERAMLRLSNPAETDGA----AKLYDQSAHYLWIGERTRQLDGAHVA
Mflv_2971|M.gilvum_PYR-GCK          VLDYERAMLRMETGDLADPALSSEPKLYDLSAHYVWIGERTRQLDGAHVA
Mvan_3540|M.vanbaalenii_PYR-1       VLDYERAMLRMNIADSADPASDGPPKLYDLSAHYVWIGERTRQLDGAHVA
MMAR_3222|M.marinum_M               VLDYERAMLRLG---EGENG---EPQLYDLSAHTVWIGERTRQLDGAHVA
MUL_3533|M.ulcerans_Agy99           VLDYERVMLRLG---EGENG---EPQLYDLSAHTVWIGERTRQLDGAHVA
Mb2200c|M.bovis_AF2122/97           VLDYERAMLRLS---DGEDG---EPQLFDLSAHTVWIGERTRQIDGAHIA
Rv2178c|M.tuberculosis_H37Rv        VLDYERAMLRLS---DGDDG---EPQLFDLSAHTVWIGERTRQIDGAHIA
MAV_2317|M.avium_104                VLDYERAMLRLS---DSDAG---EPQLYDLSAHTVWIGERTRQLDGAHIA
MLBr_00896|M.leprae_Br4923          VLDYERAMLRLAGAPEGPDD---GLQLYDLSAHTVWIGERTRQLDGAHVA
MAB_1987|M.abscessus_ATCC_1997      VLDYERAMLRLG---EDENG---EPALYDLSAHYLWIGDRTRQLDHAHVA
                                    ******.***:               *:* *** :***:****:* **:*

TH_1102|M.thermoresistible__bu      FAEVIANPIGVKIGPTTTPEVAAEYVERLDPNNEPGRLTLVSRLGNHKVR
MSMEG_4244|M.smegmatis_MC2_155      FAEVIANPIGVKLGPTTTPELAVEYVERLDPNNEPGRLTLVTRMGNNKVR
Mflv_2971|M.gilvum_PYR-GCK          FAEVIANPIGIKIGPTTSPELAVEYVERLDPNNEPGRLTLVSRMGNHKVR
Mvan_3540|M.vanbaalenii_PYR-1       FAEVIANPVGIKIGPTTSPELAVEYVERLDPNNEPGRLTLVSRMGNHKVR
MMAR_3222|M.marinum_M               FAEVIANPIGVKIGPTMTPELAVEYVERLDPHNKAGRLTLVSRLGNNKVR
MUL_3533|M.ulcerans_Agy99           FAEVIANPIGVKIGPTMTPELAVEYVERLDPHNKAGRLTLVSRLGNNKVR
Mb2200c|M.bovis_AF2122/97           FAQVIANPVGVKLGPNMTPELAVEYVERLDPHNKPGRLTLVSRMGNHKVR
Rv2178c|M.tuberculosis_H37Rv        FAQVIANPVGVKLGPNMTPELAVEYVERLDPHNKPGRLTLVSRMGNHKVR
MAV_2317|M.avium_104                FAEVIANPIGVKIGPTITPELAVEYVERLDPHNKPGRLTLVSRMGNSKVR
MLBr_00896|M.leprae_Br4923          FAEVIANPIGVKMGATMTPELAVEYVERLDPHNKPGRLTLVSRLGNNKVR
MAB_1987|M.abscessus_ATCC_1997      FAEIIANPIGMKIGPTTTPDQAVEYVERLDPHNKPGRLTFVSRMGNSKVR
                                    **::****:*:*:*.. :*: *.********:*:.****:*:*:** ***

TH_1102|M.thermoresistible__bu      DLLPPIIEKVQATGHTVIWQCDPMHGNTHESSTGYKTRHFDRIVDEVQGF
MSMEG_4244|M.smegmatis_MC2_155      DLLPPIIEKVQATGHQVIWQCDPMHGNTHESSTGYKTRHFDRIVDEVQGF
Mflv_2971|M.gilvum_PYR-GCK          DVLPPIIEKVQASGHRVIWQCDPMHGNTHESSTGYKTRHFDRIVDEVQGF
Mvan_3540|M.vanbaalenii_PYR-1       DVLPPIIEKVQASGHQVVWQCDPMHGNTHESSTGYKTRHFDRIVDEVQGF
MMAR_3222|M.marinum_M               DLLPPIVEKVQAAGHQVIWQCDPMHGNTHESSTGYKTRHFDRIVDEVQGF
MUL_3533|M.ulcerans_Agy99           DLLPPIVEKVQAAGHQVIWQCDPMHGNTHESSTGYKTRHFDRIVDEVQGF
Mb2200c|M.bovis_AF2122/97           DLLPPIVEKVQATGHQVIWQCDPMHGNTHESSTGFKTRHFDRIVDEVQGF
Rv2178c|M.tuberculosis_H37Rv        DLLPPIVEKVQATGHQVIWQCDPMHGNTHESSTGFKTRHFDRIVDEVQGF
MAV_2317|M.avium_104                DLLPPIVEKVQATGHQVIWQCDPMHGNTHESSNGYKTRHFDRIVDEVQGF
MLBr_00896|M.leprae_Br4923          DVLPPIVEKVKATGHQVIWQCDPMHGNTHESSTGYKTRHFDRVVDEVQGF
MAB_1987|M.abscessus_ATCC_1997      DLLPPIIEKVRATGHQVVWQCDPMHGNTHESPSGYKTRHFDRIVDEVQGY
                                    *:****:***:*:** *:*************..*:*******:******:

TH_1102|M.thermoresistible__bu      FEVHRALGTHPGGIHVEITGENVTECLGGAQDISDTDLAGRYETACDPRL
MSMEG_4244|M.smegmatis_MC2_155      FEVHHALGTHPGGIHVEITGENVTECLGGAQDISDSDLAGRYETACDPRL
Mflv_2971|M.gilvum_PYR-GCK          FEVHRALGTHPGGIHVEITGENVTECLGGAQDISDTDLAGRYETACDPRL
Mvan_3540|M.vanbaalenii_PYR-1       FEVHHALGTHPGGIHVEITGENVTECLGGAQDISDTDLAGRYETACDPRL
MMAR_3222|M.marinum_M               FEVHRGLGTHPGGIHVEITGENVTECLGGAQDISDSDLSGRYETACDPRL
MUL_3533|M.ulcerans_Agy99           FEVHRGLGTHPGGIHVEITGENVTECLGGAQDISDSDLSGRYETACDPRL
Mb2200c|M.bovis_AF2122/97           FEVHRALGTHPGGIHVEITGENVTECLGGAQDISETDLAGRYETACDPRL
Rv2178c|M.tuberculosis_H37Rv        FEVHRALGTHPGGIHVEITGENVTECLGGAQDISETDLAGRYETACDPRL
MAV_2317|M.avium_104                FEVHRALGTHPGGIHVEITGDNVTECLGGAQDISDMDLVGRYETACDPRL
MLBr_00896|M.leprae_Br4923          FEVHRALGTYPGGIHVEITGEDVTECLGGAQDISDTDLAGRYETACDPRL
MAB_1987|M.abscessus_ATCC_1997      FEVHNALGTHPGGIHVEITGENVTECLGGAQDISDDDLAGRYETACDPRL
                                    ****..***:**********::************: ** ***********

TH_1102|M.thermoresistible__bu      NTQQSLELAFLVAEMLRD
MSMEG_4244|M.smegmatis_MC2_155      NTQQSLELAFLVAEMLRD
Mflv_2971|M.gilvum_PYR-GCK          NTQQSLELAFLVAEMLRD
Mvan_3540|M.vanbaalenii_PYR-1       NTQQSLELAFLVAEMLRG
MMAR_3222|M.marinum_M               NTQQSLELAFLVAEMLRD
MUL_3533|M.ulcerans_Agy99           NTQQSLELAFLVAEMLRD
Mb2200c|M.bovis_AF2122/97           NTQQSLELAFLVAEMLRD
Rv2178c|M.tuberculosis_H37Rv        NTQQSLELAFLVAEMLRD
MAV_2317|M.avium_104                NTQQSLELAFLVAEMLRD
MLBr_00896|M.leprae_Br4923          NTQQSLELAFLVAEMLRD
MAB_1987|M.abscessus_ATCC_1997      NTQQSLELAFLVAEMLRD
                                    *****************.

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_1102	aroG	-	100% (462)	Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG (DAHP synthetase, phenylalanine-repressible)