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M. thermoresistible (build 8) TH_1079 ()

annotation: Probable two-component system transcriptional regulator
coordinates: 2117990 - 2118574
length: 195

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1079-100% (195)Probable two-component system transcriptional regulator
M. thermoresistible (build 8)TH_4129-3e-1536.21% (116) PUTATIVE DNA-binding response regulator MtrA
M. thermoresistible (build 8)TH_1732phoP1e-1436.92% (130) DNA-binding response regulator PhoP

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1652-5e-9088.36% (189) two-component system transcriptional regulator
M. gilvum PYR-GCKMflv_3575-4e-8988.24% (187) response regulator receiver/ANTAR domain-containing protein
M. tuberculosis H37RvRv1626-5e-9088.36% (189) two-component system transcriptional regulator
M. leprae Br4923MLBr_01286-5e-8986.77% (189) putative two-component response regulatory protein
M. abscessus ATCC 19977MAB_2627c-2e-8584.95% (186) two-component response regulatory protein
M. marinum MMMAR_2429-1e-8886.24% (189) two-component system transcriptional regulator
M. avium 104MAV_3158-9e-8886.77% (189) response regulator
M. smegmatis MC2 155MSMEG_3246-2e-9087.56% (193) response regulator
M. ulcerans Agy99MUL_1608-7e-8986.24% (189) two-component system transcriptional regulator
M. vanbaalenii PYR-1Mvan_2840-5e-9087.56% (193) response regulator receiver/ANTAR domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_1079|M.thermoresistible__bu      ---------------------------------VLVAEDEALIRLDLAEM
MSMEG_3246|M.smegmatis_MC2_155      ----------------MTGSTTD----ADRPRRVLIAEDEALIRLDLAEM
Mflv_3575|M.gilvum_PYR-GCK          MAPRSPISPAGFTMFSMSSASASPSDAAATPHRVLIAEDEALIRMDLAEM
Mvan_2840|M.vanbaalenii_PYR-1       ----------------MSSASASPSDAAVTPRRVLVAEDEALIRLDLAEM
MMAR_2429|M.marinum_M               ----------------MTGPTTDAD--AAKTRRVLIAEDEALIRMDLAEM
MUL_1608|M.ulcerans_Agy99           -------------MSVMTGPTTDAD--AAKTRRVLIAEDEALIRMDLAEM
Mb1652|M.bovis_AF2122/97            ----------------MTGPTTDAD--AAVPRRVLIAEDEALIRMDLAEM
Rv1626|M.tuberculosis_H37Rv         ----------------MTGPTTDAD--AAVPRRVLIAEDEALIRMDLAEM
MAV_3158|M.avium_104                -------------MSVMTGPTTDTD--AAVPRRVLIAEDEALIRLDLAEM
MLBr_01286|M.leprae_Br4923          ----------------MTGPTTDAD--AATPHRVLIAEDEALIRLDLAEM
MAB_2627c|M.abscessus_ATCC_199      ----------------MTGPQNTEP--AAPARRVLVAEDEALIRLDLVEM
                                                                     **:********:**.**

TH_1079|M.thermoresistible__bu      LRDEGYDVVGEAGDGQEAVELAESLRPDLVIMDVKMPRRDGIDAAREIAA
MSMEG_3246|M.smegmatis_MC2_155      LREEGYEVVGEAGDGQEAVEMAESLRPDLVIMDVKMPRRDGIDAASEIAS
Mflv_3575|M.gilvum_PYR-GCK          LREEGYEIVGEAGDGQEAVDLAESLRPDLVIMDVKMPRRDGIDAASEIAS
Mvan_2840|M.vanbaalenii_PYR-1       LREEGYEIVGEAGDGQEAVELAEALRPDLVIMDVKMPRRDGIDAASEIAS
MMAR_2429|M.marinum_M               LREEGYDIVGEAGDGQEAVELAELHKPDLVIMDVKMPRRDGIDAASEIAT
MUL_1608|M.ulcerans_Agy99           LREEGYDIVGEAGDGQEAVELAELHKPDLVIMDVKMPRRDGIDAASEIAT
Mb1652|M.bovis_AF2122/97            LREEGYEIVGEAGDGQEAVELAELHKPDLVIMDVKMPRRDGIDAASEIAS
Rv1626|M.tuberculosis_H37Rv         LREEGYEIVGEAGDGQEAVELAELHKPDLVIMDVKMPRRDGIDAASEIAS
MAV_3158|M.avium_104                LREEGYEIVGEAGDGQEAVELAERHRPDLVIMDVKMPRRDGIDAASEIAS
MLBr_01286|M.leprae_Br4923          LRDEGYDIVGEAADGQEAVELAERHKPDLVIMDVKMPRRDGIDAASEIAS
MAB_2627c|M.abscessus_ATCC_199      LHEEGYDVVGQAGDGQEAVDLAEELKPDLVIMDVKMPRRDGIDAASEIAT
                                    *::***::**:*.******::**  :******************* ***:

TH_1079|M.thermoresistible__bu      KRIAPVVVLTAFSQRDLVEQARDAGAMAYLVKPFSITDLIPAIEVAVSRF
MSMEG_3246|M.smegmatis_MC2_155      KRIAPIVILTAFSQRELVERARDAGAMAYLVKPFNINDLVPAIEVAVSRF
Mflv_3575|M.gilvum_PYR-GCK          KRIAPIVILTAFSQRELVERARDAGAMAYLVKPFSITDLIPAIEVAVSRF
Mvan_2840|M.vanbaalenii_PYR-1       KRIAPIVILTAFSQRELVERARDAGAMAYLVKPFSITDLIPAIEVAVSRF
MMAR_2429|M.marinum_M               KRIAPIVVLTAFSQRDLVERARDAGAMAYLVKPFTVSDLVPAIELAVSRF
MUL_1608|M.ulcerans_Agy99           KRIAPIVVLTAFSQRDLVERARDAGAMAYLVKPFTVSDLVPAIELAVSRF
Mb1652|M.bovis_AF2122/97            KRIAPIVVLTAFSQRDLVERARDAGAMAYLVKPFSISDLIPAIELAVSRF
Rv1626|M.tuberculosis_H37Rv         KRIAPIVVLTAFSQRDLVERARDAGAMAYLVKPFSISDLIPAIELAVSRF
MAV_3158|M.avium_104                KRIAPIVVLTAFSQRDLVERARDAGAMAYLVKPFTISDLIPAIELAVSRF
MLBr_01286|M.leprae_Br4923          KRIAPIVVLTAFSQRDLVERARDAGAMAYLVKPFTISDLIPAIALAMSRF
MAB_2627c|M.abscessus_ATCC_199      KRIAPIVILTAFSQRDLVEKARDAGAMAYLVKPFSKTDLVPAIEVAVSRF
                                    *****:*:*******:***:**************. .**:*** :*:***

TH_1079|M.thermoresistible__bu      AEITALESEVAELSERLETRKLVERAKGLLQAKHNMTEPEAFKWIQRAAM
MSMEG_3246|M.smegmatis_MC2_155      AELSALETEVATLSERLETRKLVERAKGLLQAKHKMTEPEAFKWIQRAAM
Mflv_3575|M.gilvum_PYR-GCK          SEIAELEKEVATLSDRLETRKLVERAKGLLQAKQGMTEPEAFKWIQRAAM
Mvan_2840|M.vanbaalenii_PYR-1       SEMTELEKEVANLSDRLETRKLVERAKGLLQAKQGMSEPEAFKWIQRAAM
MMAR_2429|M.marinum_M               SEISALENEVATLSDRLETRKLVERAKGLLQAKQGMTEPEAFKWIQRAAM
MUL_1608|M.ulcerans_Agy99           SEISALENEVATLSDRLETRKLVERAKGLLQAKQGMTEPEAFKWIQRAAM
Mb1652|M.bovis_AF2122/97            REITALEGEVATLSERLETRKLVERAKGLLQTKHGMTEPDAFKWIQRAAM
Rv1626|M.tuberculosis_H37Rv         REITALEGEVATLSERLETRKLVERAKGLLQTKHGMTEPDAFKWIQRAAM
MAV_3158|M.avium_104                SEIAELEREVATLSERLETRKLVERAKGLLQTEQGMTEPEAFKWIQRAAM
MLBr_01286|M.leprae_Br4923          SELTALEREVATLADRLETRKLVERAKGLLQVKQGMTEPEAFKWIQRAAM
MAB_2627c|M.abscessus_ATCC_199      GELTALEKEVQTLADRLETRKLVERAKGVLQSTQGLTEPEAFKWIQRAAM
                                     *:: ** **  *::*************:**  : ::**:**********

TH_1079|M.thermoresistible__bu      DRRTTMKRVAEVVLENLDTPKDQTPSN--
MSMEG_3246|M.smegmatis_MC2_155      DRRTTMKRVAEVVLETLDDTKQAPAPEQ-
Mflv_3575|M.gilvum_PYR-GCK          DRRTTMKRVAEVVLETLDPPAASPEPEAT
Mvan_2840|M.vanbaalenii_PYR-1       DRRTTMKRVAEVVLETLDPPADTPAGPGQ
MMAR_2429|M.marinum_M               DRRTTMKRVAEVVLETLDTPDEA------
MUL_1608|M.ulcerans_Agy99           DRRTTMKRVAEVVLETLDTPDEA------
Mb1652|M.bovis_AF2122/97            DRRTTMKRVAEVVLETLGTPKDT------
Rv1626|M.tuberculosis_H37Rv         DRRTTMKRVAEVVLETLGTPKDT------
MAV_3158|M.avium_104                DRRTTMKRVAEVVLETLGTPKE-------
MLBr_01286|M.leprae_Br4923          DRRTTMKRVAEVVLETLDTPKDT------
MAB_2627c|M.abscessus_ATCC_199      DRRTTMKRVAEVVLETLDTDAPS------
                                    ***************.*.