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M. thermoresistible (build 8) TH_1074 (trpA)

annotation: Probable tryptophan synthase, alpha subunit trpA
coordinates: 2109143 - 2109931
length: 263

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_1074 trpA - 100% (263) Probable tryptophan synthase, alpha subunit trpA

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1639 trpA 1e-117 80.46% (261) tryptophan synthase subunit alpha
M. gilvum PYR-GCK Mflv_3598 trpA 1e-121 83.21% (262) tryptophan synthase subunit alpha
M. tuberculosis H37Rv Rv1613 trpA 1e-117 80.46% (261) tryptophan synthase subunit alpha
M. leprae Br4923 MLBr_01273 trpA 1e-111 76.74% (258) tryptophan synthase subunit alpha
M. abscessus ATCC 19977 MAB_2643c trpA 1e-103 72.27% (256) tryptophan synthase subunit alpha
M. marinum M MMAR_2415 trpA 1e-115 79.46% (258) tryptophan synthase, alpha subunit TrpA
M. avium 104 MAV_3173 trpA 1e-116 80.53% (262) tryptophan synthase subunit alpha
M. smegmatis MC2 155 MSMEG_3221 trpA 1e-120 82.06% (262) tryptophan synthase subunit alpha
M. ulcerans Agy99 MUL_1593 trpA 1e-115 79.46% (258) tryptophan synthase subunit alpha
M. vanbaalenii PYR-1 Mvan_2818 trpA 1e-123 83.59% (262) tryptophan synthase subunit alpha

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3598|M.gilvum_PYR-GCK          --------MSRLAGLFDSCRAEGRSGLIGYLPTGFPDVDTSIQAMVALVE
Mvan_2818|M.vanbaalenii_PYR-1       --------MSRLAGLFDSCRAEGRSALIGYLPTGFPDVETSIAAMVALVE
TH_1074|M.thermoresistible__bu      --------MSRLAPLFESCRGEQRAALIGYLPTGFPDVATSISAMTALVE
MSMEG_3221|M.smegmatis_MC2_155      --------MSRLGAMFDSCRAEDRAALIGYLPTGFPDVPTSIAAMTALVE
Mb1639|M.bovis_AF2122/97            MVAVEQSEASRLGPVFDSCRANNRAALIGYLPTGYPDVPASVAAMTALVE
Rv1613|M.tuberculosis_H37Rv         MVAVEQSEASRLGPVFDSCRANNRAALIGYLPTGYPDVPASVAAMTALVE
MLBr_01273|M.leprae_Br4923          MMVLEQSETSRLGPVFDSCRADNRAALIGYLPTGYPDVPTSVDAMIELVE
MMAR_2415|M.marinum_M               -MTVEQREASRLGPLFDSCRAENRAALIGYLPTGYPDVNTSVRAMTELVE
MUL_1593|M.ulcerans_Agy99           -MTVEQREASRLGPLFDSCRAENRAALIGYLPTGYPDVNTSVRAMTELVE
MAV_3173|M.avium_104                -MTVKQSQASRLGPIFEACRDDDRAALIGYLPTGYPDVPTSVQAMVALVE
MAB_2643c|M.abscessus_ATCC_199      -----MTQPGRLTEVFDKCRAEERAALIGYLPNGYPDLDTSIELMTTLVR
                                             .**  :*: ** : *:.******.*:**: :*:  *  **.

Mflv_3598|M.gilvum_PYR-GCK          SGCDIVEVGVAYSDPGMDGPVIAAATEVALRGGVRVHDAFRAVEAISNAG
Mvan_2818|M.vanbaalenii_PYR-1       SGCDLIEVGIAYSDPGMDGPTIAAATEVALRGGVRVRDTFRAVEAITNAG
TH_1074|M.thermoresistible__bu      SGCDLVEVGVPYSDPGMDGPTVAAATDVALRGGVRVRDSLAAVEAISNAG
MSMEG_3221|M.smegmatis_MC2_155      SGCDLVEVGVPYSDPGMDGPTIAAATETALAGGVKVRDTLTAVEAISNAG
Mb1639|M.bovis_AF2122/97            SGCDIIEVGVPYSDPGMDGPTIARATEAALRGGVRVRDTLAAVEAISIAG
Rv1613|M.tuberculosis_H37Rv         SGCDIIEVGVPYSDPGMDGPTIARATEAALRGGVRVRDTLAAVEAISIAG
MLBr_01273|M.leprae_Br4923          SGCDIIEVGVPYSDPGMDGPTIARATEVALRGGVRVRDTLAAVEAISQAG
MMAR_2415|M.marinum_M               SGCDIVEVGVPYSDPGMDGPTIQRATEAALSGGVRVRDALTAVESISKAG
MUL_1593|M.ulcerans_Agy99           SGCDIVEVGVPYSDPGMDGPTIQRATEAALSGGVRVRDALTAVESISKAG
MAV_3173|M.avium_104                SGCDIVEVGVPYSDPGMDGPTIARATEAALHGGVRVRDTLAAVEAISAAG
MAB_2643c|M.abscessus_ATCC_199      GGCDIIEVGIAYSDPMMDGPMIAAAAETALANGVRVADVFTTVRAITDAG
                                    .***::***:.**** **** :  *::.** .**:* * : :*.:*: **

Mflv_3598|M.gilvum_PYR-GCK          GKAVVMTYWNPVLRKGVDTFARDLASAGGLGLITPDLIPDEADDWFAASE
Mvan_2818|M.vanbaalenii_PYR-1       GRAVVMTYWNPVLSKGVDAFARDLASAGGLGLITPDLIPDEADEWLAASE
TH_1074|M.thermoresistible__bu      GKAVVMSYWNPVLRWGVDAFARDLASAGGLGLITPDLIPDEADEWMAASE
MSMEG_3221|M.smegmatis_MC2_155      GRAVVMTYWNPVLRKGVDAFARDLANAGGYGLITPDLIPEEADEWMAASE
Mb1639|M.bovis_AF2122/97            GRAVVMTYWNPVLRYGVDAFARDLAAAGGLGLITPDLIPDEAQQWLAASE
Rv1613|M.tuberculosis_H37Rv         GRAVVMTYWNPVLRYGVDAFARDLAAAGGLGLITPDLIPDEAQQWLAASE
MLBr_01273|M.leprae_Br4923          GRAVVMTYWNPVLRYGVCAFARDLESAGGHGLVTPDLIPDEARQWIAASE
MMAR_2415|M.marinum_M               GRAVVMTYWNPVLRYGVDAFARDLAAAGGHGLITPDLIPDEAQQWLAASD
MUL_1593|M.ulcerans_Agy99           GRAVVMTYWNPVLRYGGDAFARDLAAAGGHGLITPDLIPDEAQQWLAASD
MAV_3173|M.avium_104                GRAVVMTYWNPVLRYGVDAFARDLAAAGGYGLITPDLIPDEAGQWLAASE
MAB_2643c|M.abscessus_ATCC_199      GHAVVMSYWNPVLRYGVDAFARELAAAGGLGIITPDLIPDEADDWIAASD
                                    *:****:******  *  :***:*  *** *::******:** :*:***:

Mflv_3598|M.gilvum_PYR-GCK          AHDLDRIFLVAPSSTPERLAETVQASRGFVYAASTMGVTGARDAVSNAAP
Mvan_2818|M.vanbaalenii_PYR-1       AHDLDRIFVVAPSSTPQRLAETVQASRGFVYAASTMGVTGARDAVSNAAP
TH_1074|M.thermoresistible__bu      AHDLDRIFLVAPSSTPERLAMTVKASRGFVYAASTMGVTGARDAVSSAAP
MSMEG_3221|M.smegmatis_MC2_155      ANDLDRIFLVAPSSTHERLAKTIEVSRGFVYAASTMGVTGARDAVSSSAP
Mb1639|M.bovis_AF2122/97            EHRLDRIFLVAPSSTPERLAATVEASRGFVYAASTMGVTGARDAVSQAAP
Rv1613|M.tuberculosis_H37Rv         EHRLDRIFLVAPSSTPERLAATVEASRGFVYAASTMGVTGARDAVSQAAP
MLBr_01273|M.leprae_Br4923          KHRLDRIFLVAPSSTPHRLVTTVGASRGFVYAVSVMGVTGARDAVSQVVP
MMAR_2415|M.marinum_M               EHGLDRIFLVAPSSTPERLANTVAASRGFVYAASTMGVTGARDAVSNAAP
MUL_1593|M.ulcerans_Agy99           AHGLDRIFLVAPSSTPERLANTVAASRGFVYAASTMGVTGARDAVSNAAP
MAV_3173|M.avium_104                RHGLDRIFLVAPSSTPQRLALTVEASRGFVYAASTMGVTGARDAVSHAAP
MAB_2643c|M.abscessus_ATCC_199      AHDLDRIFLVAPSSTPERLERTIGACRGFVYAASTMGVTGARDAVSNAAP
                                     : *****:****** .**  *: ..******.*.***********  .*

Mflv_3598|M.gilvum_PYR-GCK          ELVARVKAISDIPVGVGLGVRSREQAAEIGAYADGVIVGSALVSALKEG-
Mvan_2818|M.vanbaalenii_PYR-1       ELVRRIKGISDIPVGVGLGVRSREQAAEIASYADGVIVGSALVSALKEG-
TH_1074|M.thermoresistible__bu      ELVRRVREISQIPVGVGLGVRTAEHAAEIASYADGVIVGSALVTALTDG-
MSMEG_3221|M.smegmatis_MC2_155      ELVRRIREVSDIPVGVGLGVRSGEQAAQIGSYSDGVIVGSALVAALQDG-
Mb1639|M.bovis_AF2122/97            ELVGRVKAVSDIPVGVGLGVRSRAQAAQIAQYADGVIVGSALVTALTEG-
Rv1613|M.tuberculosis_H37Rv         ELVGRVKAVSDIPVGVGLGVRSRAQAAQIAQYADGVIVGSALVTALTEG-
MLBr_01273|M.leprae_Br4923          ELVARVKAVSDIAVGVGLGVRSREQAAQIGGYADGVIVGSALVSALGDG-
MMAR_2415|M.marinum_M               DLVARVKAVSDIPVGVGLGVRSREQAAEIGRYADGVIVGSALVSALGDG-
MUL_1593|M.ulcerans_Agy99           DLVARVKAVSDIPVGVGLGVRSREQAAEIGRYADGVIVGSALVSALGDG-
MAV_3173|M.avium_104                ELVSRVREISDIPVGVGLGVRSREQAAQIGGYADGVIVGSALVSALGDGG
MAB_2643c|M.abscessus_ATCC_199      ALVSRVREVSDIAVGVGLGVRSGAQAAEIAAYADGVIVGSALVAAAPQG-
                                     ** *:: :*:*.********:  :**:*. *:**********:*  :* 

Mflv_3598|M.gilvum_PYR-GCK          IPAVRSLTAELADGVRQRITA-
Mvan_2818|M.vanbaalenii_PYR-1       IPAVRSLTEELADGVRQRITA-
TH_1074|M.thermoresistible__bu      TPALRALTTELADGVRRRVTA-
MSMEG_3221|M.smegmatis_MC2_155      VDAVSRLTEELAGGVRRRVSA-
Mb1639|M.bovis_AF2122/97            LPRLRALTGELAAGVRLGMSA-
Rv1613|M.tuberculosis_H37Rv         LPRLRALTGELAAGVRLGMSA-
MLBr_01273|M.leprae_Br4923          LPRLRALAEELAAGVRQRTFM-
MMAR_2415|M.marinum_M               LPSLRSLTEELAAGVRQRNSP-
MUL_1593|M.ulcerans_Agy99           LPSLRSLTEELAAGVRQRKSP-
MAV_3173|M.avium_104                LTALRALTEELAAGVRQRAAAS
MAB_2643c|M.abscessus_ATCC_199      PAAVRSLAEELATGVRRA----
                                       :  *: *** ***

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_1074	trpA	-	100% (263)	Probable tryptophan synthase, alpha subunit trpA