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M. thermoresistible (build 8) TH_1035 (-)

annotation: PROBABLE MACROLIDE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER
coordinates: 2039261 - 2040937
length: 559

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1035--100% (559)PROBABLE MACROLIDE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER
M. thermoresistible (build 8)TH_4108-2e-7234.05% (514) PUTATIVE ABC transporter related
M. thermoresistible (build 8)TH_3270-6e-6331.85% (540) PUTATIVE ABC transporter-related protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2504c-0.090.31% (557) putative ABC transporter ATP-binding protein
M. gilvum PYR-GCKMflv_2568-0.089.96% (558) putative ABC transporter ATP-binding protein
M. tuberculosis H37RvRv2477c-0.090.31% (557) putative ABC transporter ATP-binding protein
M. leprae Br4923MLBr_01248-0.088.89% (558) putative ABC transporter ATP-binding protein
M. abscessus ATCC 19977MAB_1560-0.089.25% (558) putative ABC transporter ATP-binding protein
M. marinum MMMAR_3830-0.091.04% (558) ATP-binding component of an ABC transporter
M. avium 104MAV_1695-0.091.94% (558) putative ABC transporter ATP-binding protein
M. smegmatis MC2 155MSMEG_4700-0.090.68% (558) putative ABC transporter ATP-binding protein
M. ulcerans Agy99MUL_3757-0.090.32% (558) putative ABC transporter ATP-binding protein
M. vanbaalenii PYR-1Mvan_4070-0.091.20% (557) putative ABC transporter ATP-binding protein

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_3830|M.marinum_M               MAEFIYTMKKVRKAHGDKVILDDVTLSFYPGAKIGVVGPNGAGKSSVLRI
MUL_3757|M.ulcerans_Agy99           MAEFIYTMKKVRKAHGDKVILDDVTLSFYPGAKIGVVGPNGAGKSSVLRI
MAV_1695|M.avium_104                MAEFIYTMKKVRKAHGDKVILDDVTLSFYPGAKIGVVGPNGAGKSSVLRI
Mb2504c|M.bovis_AF2122/97           MAEFIYTMKKVRKAHGDKVILDDVTLSFYPGAKIGVVGPNGAGKSSVLRI
Rv2477c|M.tuberculosis_H37Rv        MAEFIYTMKKVRKAHGDKVILDDVTLSFYPGAKIGVVGPNGAGKSSVLRI
MLBr_01248|M.leprae_Br4923          MAEFIYTMKKVRKAHGDKVILDDVTLNFFPGAKIGVVGPNGAGKSSVLRI
TH_1035|M.thermoresistible__bu      MAEFIYTMRKVRKAHGDKVILDDVSLNFLPGAKIGVVGPNGAGKSSVLRI
Mflv_2568|M.gilvum_PYR-GCK          MAEFIYTMRKVRKAHGDKVILDDVTLNFLPGAKIGVVGPNGAGKSSVLRI
Mvan_4070|M.vanbaalenii_PYR-1       MAEFIYTMRKVRKAHGDKVILDDVTLNFLPGAKIGVVGPNGAGKSSVLRI
MSMEG_4700|M.smegmatis_MC2_155      MAEFIYTMRKVRKAHGDKVILDDVTLNFLPGAKIGVVGPNGAGKSSVLRI
MAB_1560|M.abscessus_ATCC_1997      MAEYIYTMMKVRKAHGDKVILDDVTLNFLPGAKIGVVGPNGAGKSSVLKI
                                    ***:**** ***************:*.* *******************:*

MMAR_3830|M.marinum_M               MAGLDKPNNGDAFLATGATVGILLQEPPLNEEKTVRGNVEEGLGDIKVKL
MUL_3757|M.ulcerans_Agy99           IAGLDKPNNGDAFLATGATVGILLQEPPLNEEKTVRGNVEEGLGDIKVKL
MAV_1695|M.avium_104                MAGLDKPNNGEAFLATDATVGILQQEPPLNEEKTVRGNVEEGLGEIKVKL
Mb2504c|M.bovis_AF2122/97           MAGLDKPNNGDAFLATGATVGILQQEPPLNEDKTVRGNVEEGMGDIKIKL
Rv2477c|M.tuberculosis_H37Rv        MAGLDKPNNGDAFLATGATVGILQQEPPLNEDKTVRGNVEEGMGDIKIKL
MLBr_01248|M.leprae_Br4923          MAGMDKPNNGDAFLATGASVGILQQEPPLNEEKTVRGNVEEGLGDIKIKL
TH_1035|M.thermoresistible__bu      MAGLDQPNNGEAFLQPGATVGILLQEPPLNEEKTVRGNVEEGLGEIKVKL
Mflv_2568|M.gilvum_PYR-GCK          MAGLDQPNNGDAFLQPGATVGILMQEPQLDETKTVRENVEDGV-AIKGKL
Mvan_4070|M.vanbaalenii_PYR-1       MAGLDQPNNGDAFLAPGATVGILLQEPELDETKTVRENVEEGV-AIKAKL
MSMEG_4700|M.smegmatis_MC2_155      MAGLDQPNNGDAFLAPDATVGILMQEPQLDETKTVRENVEDGV-AIKGKL
MAB_1560|M.abscessus_ATCC_1997      MAGLDKPNNGEAFLANGASVGILQQEPPLDETKTVRENVEDGV-AVKAKL
                                    :**:*:****:***  .*:**** *** *:* **** ***:*:  :* **

MMAR_3830|M.marinum_M               DRFNEVAELMATDYSDELMEEMGRLQEDLDHADAWDIDSQLEQAMDALRC
MUL_3757|M.ulcerans_Agy99           DRFNEVAELMATDYSDELMEEMGRLQEDLDHADAWDIDSQLEQAMDALRC
MAV_1695|M.avium_104                DRFNEVAELMATDYSDELMEEMGRLQEELDHADAWDLDSQLEQAMDALRC
Mb2504c|M.bovis_AF2122/97           DRFNEVAELMATDYTDELMEEMGRLQEELDHADAWDLDAQLEQAMDALRC
Rv2477c|M.tuberculosis_H37Rv        DRFNEVAELMATDYTDELMEEMGRLQEELDHADAWDLDAQLEQAMDALRC
MLBr_01248|M.leprae_Br4923          DRFSEVAELMATDSSSELMEEMGRLQEELDHADAWDLDSQLEQAMDVLRC
TH_1035|M.thermoresistible__bu      DRFNEVAELMATDYSDELMEEMGRLQEELDHADAWDLDSQLEQAMDALRC
Mflv_2568|M.gilvum_PYR-GCK          NRYNEVAELMATDYTDELMDEMGKLQEELDAADAWDIDSQLEQAMDALRC
Mvan_4070|M.vanbaalenii_PYR-1       NRYNEVAELMATDYTDELMEEMGKLQEELDAADAWDIDSQLEQAMDALRC
MSMEG_4700|M.smegmatis_MC2_155      NRYNEVAELMATDYSDELMEEMGKLQEELDAADAWDIDSQLEQAMDALRC
MAB_1560|M.abscessus_ATCC_1997      NRYNEVAELMATDYSDELMEEMGKLQEELDAADAWDIDSQLEQAMDALRC
                                    :*:.********* :.***:***:***:** *****:*:*******.***

MMAR_3830|M.marinum_M               PPPEEPVANLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVQWLEQ
MUL_3757|M.ulcerans_Agy99           PPPEEPVANLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVQWLEQ
MAV_1695|M.avium_104                PPPDDPVTNLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVQWLEQ
Mb2504c|M.bovis_AF2122/97           PPADEPVTNLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVQWLEQ
Rv2477c|M.tuberculosis_H37Rv        PPADEPVTNLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVQWLEQ
MLBr_01248|M.leprae_Br4923          PPPDEPVTNLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVQWLEQ
TH_1035|M.thermoresistible__bu      PPPDEPVTHLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVLWLEQ
Mflv_2568|M.gilvum_PYR-GCK          PPPDEPVTHLSGGEKRRVALCKLLLSKPDLLLLDEPTNHLDAESVLWLEQ
Mvan_4070|M.vanbaalenii_PYR-1       PPPDEPVTHLSGGEKRRVALCKLLLSKPDLLLLDEPTNHLDAESVLWLEQ
MSMEG_4700|M.smegmatis_MC2_155      PPPDEPVTHLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVLWLEQ
MAB_1560|M.abscessus_ATCC_1997      PPPDEPVTHLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVLWLEQ
                                    **.::**::*****:****************************** ****

MMAR_3830|M.marinum_M               HLASYAGAVLAVTHDRYFLDNVAEWILELDRGRAYPYEGNYSTYLEKKAD
MUL_3757|M.ulcerans_Agy99           HLASYAGAVLAVTHDRYFLDNVAEWILELDRGRTYPYEGNYSTYLEKKAD
MAV_1695|M.avium_104                HLAAYAGAVLAVTHDRYFLDNVAQWILELDRGRAYPYEGNYSTYLEKKAD
Mb2504c|M.bovis_AF2122/97           HLASYPGAILAVTHDRYFLDNVAEWILELDRGRAYPYEGNYSTYLEKKAE
Rv2477c|M.tuberculosis_H37Rv        HLASYPGAILAVTHDRYFLDNVAEWILELDRGRAYPYEGNYSTYLEKKAE
MLBr_01248|M.leprae_Br4923          HLAGYAGAVLAVTHDRYFLDNVAEWILELDRGRAYPYEGNYSTYLEKKAE
TH_1035|M.thermoresistible__bu      HLAEYKGAVLAVTHDRYFLDNVAEWILELDRGRAYPYEGNYSTYLEKKAE
Mflv_2568|M.gilvum_PYR-GCK          HLAEYKGAILAVTHDRYFLDNVAEWILELDRGRAYPYEGNYSTYLEKKAE
Mvan_4070|M.vanbaalenii_PYR-1       HLAEYKGAVLAVTHDRYFLDNVAEWILELDRGRAFPYEGNYSTYLEKKAE
MSMEG_4700|M.smegmatis_MC2_155      HLASYPGAILAVTHDRYFLDNVAEWILELDRGRAYPYEGNYSTYLEKKAE
MAB_1560|M.abscessus_ATCC_1997      HLATYPGAILAVTHDRYFLDNVAEWILELDRGRAYPYEGNYSTYLEKKAE
                                    *** * **:**************:*********::**************:

MMAR_3830|M.marinum_M               RLAVQGRKDAKLQKRLQEELAWVRSGAKARQAKSKARLQRYEEMVAEAEK
MUL_3757|M.ulcerans_Agy99           RLAVQGRKDAKLQKRLQEELAWVRSGAKARQAKSKARLQRYEEMVAEAEK
MAV_1695|M.avium_104                RLAVQGRKDAKLQKRLSEELAWVRSGAKARQAKSKARLQRYEEMAAEAEK
Mb2504c|M.bovis_AF2122/97           RLAVQGRKDAKLQKRLTEELAWVRSGAKARQAKSKARLQRYEEMAAEAEK
Rv2477c|M.tuberculosis_H37Rv        RLAVQGRKDAKLQKRLTEELAWVRSGAKARQAKSKARLQRYEEMAAEAEK
MLBr_01248|M.leprae_Br4923          RLTTQGRKDAKLQKRLTDELAWVRSGAKARQAKSKARLQRYEEMAAEAEK
TH_1035|M.thermoresistible__bu      RLEVQGRKDAKLHKRLKEELAWVRSGTKARQAKGKARLQRYEEMAAEAEK
Mflv_2568|M.gilvum_PYR-GCK          RIAVTGRKDAKLQKRLKDELEWVRSGAKARQAKNKARLQRYEEMAAEAEK
Mvan_4070|M.vanbaalenii_PYR-1       RIAVQGRKDAKLQKRLKDELDWVRSGAKARQAKSKARLQRYEEMAAEAEK
MSMEG_4700|M.smegmatis_MC2_155      RLEVQGKKDQKLQKRLKEELAWVRSGAKARQAKNKARLDRYEEMVAEAEK
MAB_1560|M.abscessus_ATCC_1997      RIAVQGRKDAKLHKRLQEELAWVRSGAKARQAKNKARLQRYEEMVTEAEK
                                    *: . *:** **:*** :** *****:******.****:*****.:****

MMAR_3830|M.marinum_M               TRKLDFEEIQIPVGPRLGSVVVEVEHLDKGFGGRTLIKDLSFTLPRNGIV
MUL_3757|M.ulcerans_Agy99           TRKLDFEEIQIPVGPRLGSVVVEVEHLDKGFGGRTLIKDLSFTLPRNGTV
MAV_1695|M.avium_104                TRKLDFEEIQIPVGPRLGNVVVEVEHLDKGYDGRTLIKDLSFTLPRNGIV
Mb2504c|M.bovis_AF2122/97           TRKLDFEEIQIPVGPRLGNVVVEVDHLDKGYDGRALIKDLSFSLPRNGIV
Rv2477c|M.tuberculosis_H37Rv        TRKLDFEEIQIPVGPRLGNVVVEVDHLDKGYDGRALIKDLSFSLPRNGIV
MLBr_01248|M.leprae_Br4923          NRKFDFEEIQIPVGPRLGNMVVEVEHLDKGYGGRTLIKDLSFTLPRNGIV
TH_1035|M.thermoresistible__bu      SRKLDFEEIQIPTPPRLGNVVVEVKNLDKGYDGRPLIKDLSFTLPRNGIV
Mflv_2568|M.gilvum_PYR-GCK          TRKLDFEEIQIPVGPRLGNVVVEVEHLDKGFDGRLLIKDLSFTLPRNGIV
Mvan_4070|M.vanbaalenii_PYR-1       TRKLDFEEIQIPTGPRLGNVVVEVEHLDKGFGGRQLIKDLSFTLPRNGIV
MSMEG_4700|M.smegmatis_MC2_155      TRKLDFEEIQIPTPPRLGSVVVEVEHLDKGFNGRTLIKDLSFTLPRNGIV
MAB_1560|M.abscessus_ATCC_1997      TRKLDFEEIQIPTGPRLGNVVVEVEHLDKGFEGRALIKDLSFTLPRNGIV
                                    .**:********. ****.:****.:****: ** *******:***** *

MMAR_3830|M.marinum_M               GVIGPNGVGKTTLFKTIVGLEEPDSGTVKVGETVKLSYVDQTRAGIDPKK
MUL_3757|M.ulcerans_Agy99           GVIGPNGVGKTTLFKTIVGLEEPDSGTVKVGETVKLSYVDQTRAGIDPKK
MAV_1695|M.avium_104                GVIGPNGVGKTTLFKTIVGLEQPDSGTVKVGETVKLSYVDQARAGIDPKK
Mb2504c|M.bovis_AF2122/97           GVIGPNGVGKTTLFKTIVGLETPDSGSVKVGETVKLSYVDQARAGIDPRK
Rv2477c|M.tuberculosis_H37Rv        GVIGPNGVGKTTLFKTIVGLETPDSGSVKVGETVKLSYVDQARAGIDPRK
MLBr_01248|M.leprae_Br4923          GIIGPNGVGKTTLFKTIVGLEQPDGGAVKIGETVKLSYVDQTRAGIDPKK
TH_1035|M.thermoresistible__bu      GVIGPNGVGKTTLFKTIVGLEEPDSGTVKIGETVKLSYVDQTRAGIDPNK
Mflv_2568|M.gilvum_PYR-GCK          GVIGPNGVGKTTLFKTIVGLEEPDSGTVKVGETVKLSYVDQTRGGIDPKK
Mvan_4070|M.vanbaalenii_PYR-1       GVIGPNGVGKTTLFKTIVGLEQPDSGTVKIGETVKLSYVDQSRAGIDPKK
MSMEG_4700|M.smegmatis_MC2_155      GVIGPNGVGKTTLFKTIVGLEQPDSGTVKIGETVKLSYVDQTRAGIDPKK
MAB_1560|M.abscessus_ATCC_1997      GVIGPNGVGKTTLFKTIVGLENPDGGEVKVGETVKLSYVDQSRAGIDPKK
                                    *:******************* **.* **:***********:*.****.*

MMAR_3830|M.marinum_M               TVWEVVSDGLDYIEVGQSEVPSRAYVSAFGFKGPDQQKPAGVLSGGERNR
MUL_3757|M.ulcerans_Agy99           TVWEVVSDGLDSIEVGQSEVPSRAYVSAFGFKGPDQQKPAGVLSGGERNR
MAV_1695|M.avium_104                TVWEVVSDGLDYIEVGQNEVPSRAYVSAFGFKGPDQQKPAGVLSGGERNR
Mb2504c|M.bovis_AF2122/97           TVWEVVSDGLDYIQVGQTEVPSRAYVSAFGFKGPDQQKPAGVLSGGERNR
Rv2477c|M.tuberculosis_H37Rv        TVWEVVSDGLDYIQVGQTEVPSRAYVSAFGFKGPDQQKPAGVLSGGERNR
MLBr_01248|M.leprae_Br4923          IVWEVVSDGLDHIQVGQTEVSSRAYVSAFGFKGPDQQKLAGVLSGGERNR
TH_1035|M.thermoresistible__bu      TVWEVVSDGLDYIEVGQNEIPSRAYVSAFGFKGPDQQKPAGVLSGGERNR
Mflv_2568|M.gilvum_PYR-GCK          TVWEVVSDGLDFIEVGQNEVPSRAYVSAFGFKGPDQQKPAGVLSGGERNR
Mvan_4070|M.vanbaalenii_PYR-1       TVWEVVSDGLDYIEVGQNEIPSRAYVSAFGFKGPDQQKPAGVLSGGERNR
MSMEG_4700|M.smegmatis_MC2_155      TVWQVVSDGLDYIEVGQNEIPSRAYVSAFGFKGPDQQKPAGVLSGGERNR
MAB_1560|M.abscessus_ATCC_1997      NVWEVVSDGLDHIVVGQNEMPSRAYVSAFGFKGPDQQKPAGVLSGGERNR
                                     **:******* * ***.*:.***************** ***********

MMAR_3830|M.marinum_M               LNLALTLKQGGNLILLDEPTNDLDVETLSSLENALVNFPGCAVVISHDRW
MUL_3757|M.ulcerans_Agy99           LNLALTLKQGGNLILLDEPTNDLDVETLSSLENALVNFPGCAVVISHDRW
MAV_1695|M.avium_104                LNLALTLKQGGNLILLDEPTNDLDVETLGSLENALVNFPGCAVVISHDRW
Mb2504c|M.bovis_AF2122/97           LNLALTLKQGGNLILLDEPTNDLDVETLGSLENALLNFPGCAVVISHDRW
Rv2477c|M.tuberculosis_H37Rv        LNLALTLKQGGNLILLDEPTNDLDVETLGSLENALLNFPGCAVVISHDRW
MLBr_01248|M.leprae_Br4923          LNLALTLKQGGNLILLDEPTNDLDVETLGSLENALVNFPGCAVVISHDRW
TH_1035|M.thermoresistible__bu      LNLALTLKEGGNLILLDEPTNDLDVETLGSLENALEKFPGCAVVISHDRW
Mflv_2568|M.gilvum_PYR-GCK          LNLALTLKEGGNLILLDEPTNDLDVETLSSLENALQNFPGCAVVISHDRW
Mvan_4070|M.vanbaalenii_PYR-1       LNLALTLKEGGNLLLLDEPTNDLDVETLSSLENALEKFPGCAVVISHDRW
MSMEG_4700|M.smegmatis_MC2_155      LNLALTLKEGGNLILLDEPTNDLDVETLSSLENALQQFPGCAVVISHDRW
MAB_1560|M.abscessus_ATCC_1997      LNLALTLKQGGNLILLDEPTNDLDVETLGSLENALEQFPGCAVVISHDRW
                                    ********:****:**************.****** :*************

MMAR_3830|M.marinum_M               FLDRTCTHILAWEGDADSEAKWFWFEGNFGAYEENKVERLGVEAARPHRV
MUL_3757|M.ulcerans_Agy99           FLDRTCTHILAWEGDADSEAKWFWFEGNFGAYEENKVERLGVEAARPHRV
MAV_1695|M.avium_104                FLDRTCTHILAWEGDDDNEAKWFWFEGNFGAYEENKIERLGAEAARPHRV
Mb2504c|M.bovis_AF2122/97           FLDRTCTHILAWEGDDDNEAKWFWFEGNFGAYEENKVERLGVDAARPHRV
Rv2477c|M.tuberculosis_H37Rv        FLDRTCTHILAWEGDDDNEAKWFWFEGNFGAYEENKVERLGVDAARPHRV
MLBr_01248|M.leprae_Br4923          FLDRTCTHILAWEGDD--EGKWFWFEGNFGAYEENKVERLGAEAARPHRV
TH_1035|M.thermoresistible__bu      FLDRVCTHILAWEGTEDNPAQWFWFEGNFAAYEENKVARLGPEAARPHRV
Mflv_2568|M.gilvum_PYR-GCK          FLDRTCTHILAWEGDSDNEAKWFWFEGNFGGYEENKIERLGADAARPHRV
Mvan_4070|M.vanbaalenii_PYR-1       FLDRTCTHILAWEGDADNEAKWFWFEGNFGGYEENKIERLGAEAARPHRV
MSMEG_4700|M.smegmatis_MC2_155      FLDRTCTHILAWEGDDDNEAKWFWFEGNFGAYEENKIQRMGAEAARPHRV
MAB_1560|M.abscessus_ATCC_1997      FLDRTCTHILAWEGSDDNPASWFWFEGNFQAYEENKVERLGIDAARPHRV
                                    ****.*********     ..******** .*****: *:* :*******

MMAR_3830|M.marinum_M               THRRLTRD
MUL_3757|M.ulcerans_Agy99           THRRLTRD
MAV_1695|M.avium_104                THRKLTRD
Mb2504c|M.bovis_AF2122/97           THRKLTRG
Rv2477c|M.tuberculosis_H37Rv        THRKLTRG
MLBr_01248|M.leprae_Br4923          THRKLTRD
TH_1035|M.thermoresistible__bu      THRRLTRD
Mflv_2568|M.gilvum_PYR-GCK          THRKLTRD
Mvan_4070|M.vanbaalenii_PYR-1       THRKLTRG
MSMEG_4700|M.smegmatis_MC2_155      THRRLTRD
MAB_1560|M.abscessus_ATCC_1997      THRRLTRD
                                    ***:***.